V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains; in several T-cell receptors such as
CD2
CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells.
It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette rece ...
(Cluster of Differentiation 2),
CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic ce ...
,
CD80
The Cluster of differentiation 80 (also CD80 and B7-1) is a B7, type I membrane protein in the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is cl ...
, and
CD86
Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein constitutively expressed on dendritic cells, Langerhans cells, macrophages, B-cells (including memory B-cells), and on other antigen-presenting cells. Along with CD80, CD ...
; in
myelin
Myelin is a lipid-rich material that surrounds nerve cell axons (the nervous system's "wires") to insulate them and increase the rate at which electrical impulses (called action potentials) are passed along the axon. The myelinated axon can be l ...
membrane adhesion molecules; in
junctional adhesion molecule
A junctional adhesion molecule (JAM) is a protein that is a member of the immunoglobulin superfamily, and is expressed in a variety of different tissues, such as leukocytes, platelets, and epithelial and endothelial cells. They have been shown to ...
s (JAM); in
tyrosine-protein kinase receptors; and in the
programmed cell death protein 1
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein on the surface of T and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regula ...
(PD1).
Subfamilies
*
Immunoglobulin V-set, subgroup
*
T-cell surface antigen CD2
Human proteins containing this domain
ACAM;
ACAN;
ADAMTSL1;
AGC1;
AMICA1;
BCAM BCAM may stand for:
* Basal cell adhesion molecule
* Basque Center for Applied Mathematics
* Breast Cancer Awareness Month
Breast Cancer Awareness Month (BCAM), also referred to in the United States as National Breast Cancer Awareness Month (NB ...
;
BCAN
Brevican core protein is a protein that in humans is encoded by the ''BCAN'' gene. Brevican is a member of the lectican protein family.
Brevican is localised to the surface of neurons in the brain. In melanocytic cells, BCAN gene expression ...
;
BGP;
BGPc;
BT3.3;
BTN1A1
Butyrophilin subfamily 1 member A1 is a protein that in humans is encoded by the ''BTN1A1'' gene.
Butyrophilin (BTN) is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a ...
;
BTN2A1;
BTN2A2;
BTN2A3;
BTN3A1
Butyrophilin subfamily 3 member A1 is a protein that in humans is encoded by the ''BTN3A1'' gene.
References
External links
*
Further reading
*
*
*
*
*
*
*
{{gene-6-stub ...
;
BTN3A2;
BTN3A3
Butyrophilin subfamily 3 member A3 is a protein that in humans is encoded by the ''BTN3A3'' gene.
References
Further reading
*
*
*
*
External links
*
*
*
*
{{gene-6-stub ...
;
BTNL2
Butyrophilin-like protein 2 is a protein that in humans is encoded by the ''BTNL2'' gene.
Because it is associated with the immune system and the major histocompatibility complex, it has been implicated in many diseases (see further reading li ...
;
BTNL3;
BTNL8;
BTNL9;
C10orf54
V-domain Ig suppressor of T cell activation (VISTA) is a type I transmembrane protein that functions as an immune checkpoint and is encoded by the ''C10orf54'' gene.
Structure and function
VISTA is approximately 50k Da and belongs to the i ...
;
C1orf32;
C9orf94;
CADM1
Cell adhesion molecule 1 is a protein that, in humans, is encoded by the ''CADM1'' gene.
Model organisms
Model organisms have been used in the study of CADM1 function. A conditional knockout mouse line, called ''Cadm1tm1.2Brd'' was generated. M ...
;
CADM2;
CADM3;
CADM4;
CD2
CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells.
It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette rece ...
;
CD226;
CD274
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the ''CD274'' gene.
Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protei ...
;
CD276
Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the gene.
Structure
B7-H3 is a 316 amino acid-long type I transmembrane protein, existing in two isoforms determined by its extracellular domain. In m ...
;
CD300A;
CD300C;
CD300D;
CD300E;
CD300LB;
CD300LF
CMRF35-like molecule 1, also known as CD300lf, is a protein that in humans is encoded by the CD''300LF'' gene. CD300lf belongs to the protein family of CD300. CD300lf is a membrane glycoprotein that contains an immunoglobulin domain and is express ...
;
CD300LG;
CD33
CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.
...
;
CD3G
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the ''CD3G'' gene.
T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the fo ...
;
CD7
CD7 (Cluster of Differentiation 7) is a protein that in humans is encoded by the ''CD7'' gene.
Function
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and matur ...
;
CD79A
Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.
The CD79a protein together with the related C ...
;
CD79B
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.
It is associated with agammaglobulinemia-6.
The B lymphocyte antigen receptor is a multimeric complex that includes the antige ...
;
CD80
The Cluster of differentiation 80 (also CD80 and B7-1) is a B7, type I membrane protein in the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is cl ...
;
CD83
CD83 (Cluster of Differentiation 83) is a human protein encoded by the gene.
Structure
The membrane-bound form of CD83 consists of an extracellular V-type immunoglobulin-like domain, a transmembrane domain and a cytoplasmic signaling tail. A ...
;
CD86
Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein constitutively expressed on dendritic cells, Langerhans cells, macrophages, B-cells (including memory B-cells), and on other antigen-presenting cells. Along with CD80, CD ...
;
CD8A
CD8a (Cluster of Differentiation 8a), is a human gene.
Function
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, act ...
;
CD8B;
CD8B1;
CD96;
CEACAM1
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.
Function
...
;
CEACAM16;
CEACAM19;
CEACAM21;
CEACAM3
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a member of the carcinoembryonic antigen (CEA) gene family..
This gene encodes a member of the family of carcinoembryonic ...
;
CEACAM4;
CEACAM5;
CEACAM6
Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen (CEA) gene family..
See also
* Cluster of ...
;
CEACAM7;
CEACAM8
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), is a member of the carcinoembryonic antigen (CEA) gene family. Its main function is cell adhesion, cell migration, and pathog ...
;
CHL1
Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the ''CHL1'' gene.
CHL1 is a cell adhesion molecule
Cell adhesion molecules (CAMs) are a subset of cell surface pr ...
;
CREA7-4;
CRTAM;
CSF1R
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human ''CSF1R'' gene (known also as c-FMS). CS ...
;
CTLA4
CTLA-4 or CTLA4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA-4 is constitutively expr ...
;
CXADR
Coxsackievirus and adenovirus receptor (CAR) is a protein that in humans is encoded by the ''CXADR'' gene. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. CAR protein is ...
;
ERMAP;
ESAM;
F11R
Junctional adhesion molecule A is a protein that in humans is encoded by the ''F11R'' gene. It has also been designated as CD321 ( cluster of differentiation 321).
Function
Tight junctions represent one mode of cell-to-cell adhesion in epithe ...
;
FCAMR;
FCRL2
Fc receptor-like protein 2 is a protein that in humans is encoded by the ''FCRL2'' gene.
References
Further reading
*
*
*
*
*
*
*
*
*
Fc receptors
{{gene-1-stub ...
;
FKSG87;
GLUDP5
Glutamate dehydrogenase pseudogene 5, also known as GLUDP5, is a human gene.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
Pseudogenes
{{protein-stub ...
;
GPA33;
HAPLN1
Hyaluronan and proteoglycan link protein 1 is a protein that in humans is encoded by the ''HAPLN1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meanin ...
;
HAPLN2
Hyaluronan and proteoglycan link protein 2 (HAPLN2) also known as brain link protein 1 (BRAL1) is a protein that in humans is encoded by the ''HAPLN2'' gene. HAPLN1 codes for a related link protein that is expressed in cartilage while Bral1 is e ...
;
HAPLN3;
HAPLN4;
HAVCR1
Hepatitis A virus cellular receptor 1 (HAVcr-1) also known as T-cell immunoglobulin and mucin domain 1 (TIM-1) is a protein that in humans is encoded by the ''HAVCR1'' gene.
It is also known as KIM-1 Kidney Injury Molecule -1, which is a protein ...
;
HEPACAM
Gene HEPACAM*, named based on its original site of identification - hepatocytes and the nature of its protein product - a cell adhesion molecule (CAM), was first discovered and characterised in human liver and reported by Shali Shen (MD, PhD) in ...
;
HHLA2;
HSPG2
Perlecan (PLC) also known as basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) or heparan sulfate proteoglycan 2 (HSPG2), is a protein that in humans is encoded by the ''HSPG2'' gene. The HSPG2 gene codes for a 4,391 amin ...
;
ICOSLG
ICOS ligand (ICOSLG, ICOSL or GL50) is a protein that in humans is encoded by the ''ICOSLG'' gene located at chromosome 21. ICOSLG has also been designated as CD275 (cluster of differentiation 275).
ICOSLG is glycosylated transmembrane structure, ...
;
IGHA1;
IGHA2
Ig alpha-2 chain C region is a protein that in humans is encoded by the ''IGHA2'' gene.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
{{protein-stub
Proteins ...
;
IGHD
Ig delta chain C region is a protein that in humans is encoded by the ''IGHD'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ...
;
IGHG1
Ig gamma-1 chain C region is a protein that in humans is encoded by the ''IGHG1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' o ...
;
IGHG3
Ig gamma-3 chain C region is a protein that in humans is encoded by the ''IGHG3'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' ...
;
IGHM
Ig mu chain C region is a protein that in humans is encoded by the ''IGHM'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''b ...
;
IGHV1-69;
IGHV4-31;
IGHV7-81;
IGKC;
IGKV1-5;
IGKV2-24;
IGL@
Immunoglobulin lambda locus, also known as IGL@, is a region on the q arm of human chromosome 22, region 11.22 (22q11.22) that contains genes for the lambda light chains of antibodies (or immunoglobulins).
Function
Immunoglobulins recogniz ...
;
IGLC1;
IGLV2-14;
IGLV3-21;
IGLV3-25;
IGLV4-3;
IGLV5-52;
IGLV6-57;
IGSF11;
IGSF2
Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene.
See also
* Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification de ...
;
IGSF3;
IGSF6;
IGSF8;
IGSF9;
IL18R1
The interleukin-18 receptor 1 (IL-18R1) is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is its human gene. IL18R1 is also known as CDw218a (cluster of differentiation w218a).
The protein encoded by this gene is a cytokine rec ...
;
IREM2;
IREM3;
JAM2
Junctional adhesion molecule B is a protein that in humans is encoded by the ''JAM2'' gene. JAM2 has also been designated as CD322 (cluster of differentiation 322).
Function
Tight junctions represent one mode of cell-to-cell adhesion in endoth ...
;
JAM3
Junctional adhesion molecule C is a protein that in humans is encoded by the ''JAM3'' gene.
Gene
This gene is located on the long arm of chromosome 11 (11q25) on the Watson strand. It is 83,077 bases in length. The encoded protein is 310 amino ...
;
KDR;
KIRREL
Kin of IRRE-like protein 1, also known as NEPH1, is a protein that in humans is encoded by the ''KIRREL'' gene.
Function
NEPH1 is a member of the NEPH protein family, which includes NEPH2 ( KIRREL3, MIMbr>607761 and NEPH3 ( KIRREL2, MIMbr>60 ...
;
KIRREL2
Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the ''KIRREL2'' gene. It is primarily expressed in β cells of the pancreatic islets.
KIRREL2 is a member of the NEPH protein family, which includes NEPH1 ...
;
KIRREL3
Kin of IRRE-like protein 3 (KIRREL3) also known as kin of irregular chiasm-like protein 3 or NEPH2 is a protein that in humans is encoded by the ''KIRREL3'' gene.
NEPH2 is a member of the NEPH protein family of transmembrane proteins, which inc ...
;
LAG3
Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the ''LAG3'' gene. LAG3, which was discovered in 1990 and was designated CD223 ( cluster of differentiation 223) after the Seventh Human Leucocyte Dif ...
;
LOC253012
LOC, L.O.C., Loc, LoC, or locs may refer to:
Places
* Lóc, a village in Sângeorgiu de Pădure, Mureș County, Romania
* Lócs, a village in Vas county, Hungary
* Line of Contact, meeting place of Western and Eastern Allied forces at the end ...
;
LOC402482;
MAG;
MGC33530;
MOG
Mog may refer to:
Entertainment Characters
* Mog (''Final Fantasy VI''), in the game
* Mog (Judith Kerr), a cat in Kerr's children's books
* Mog, a half-man/half-dog in the film ''Spaceballs''
* A cat in the Meg and Mog children's books by Helen ...
;
MPZ MPZ or mpz may refer to:
* Myelin protein zero, a single membrane glycoprotein which in humans is encoded by the MPZ gene
* MPZ, the DS100 code for Penzberg station, Bavaria, Germany
* MPZ, the IATA and FAA LID code for Mount Pleasant Municipal Ai ...
;
MPZL1;
MPZL2;
MXRA8
Matrix remodeling-associated protein 8 is a protein that in humans is encoded by the ''MXRA8'' gene.
MXRA8 protein is a receptor for multiple arthritogenic alphaviruses, including chikungunya, Ross River, Mayaro and O'nyong nyong viruses.
...
;
MYBPC3
The myosin-binding protein C, cardiac-type is a protein that in humans is encoded by the ''MYBPC3'' gene. This isoform is expressed exclusively in heart muscle during human and mouse development, and is distinct from those expressed in slow skelet ...
;
NCA
NCA may refer to:
Businessses and organisations Australia
* National Capital Authority, a government authority for development planning of the Capital Territory
* National Crime Authority, defunct investigative agency
India
* Nuclear Command Aut ...
;
NCR2
Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the ''NCR2'' gene. NCR2 has also been designated as CD336 (cluster of differentiation
The cluster of differentiation (also known as cluster of designation or cla ...
;
NCR3
Natural cytotoxicity triggering receptor 3 is a protein that in humans is encoded by the ''NCR3'' gene. NCR3 has also been designated as CD337 (cluster of differentiation 337) and as NKp30. NCR3 belongs to the family of NCR membrane receptors toget ...
;
NPHS1
Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. The renal filtration barrier consists of fenestrated endothelial cells, the glomerular basement membrane, and the podocytes of epithelial cells. Nephrin is ...
;
OBSL1;
OPCML;
P0;
PDCD1;
PIGR
Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the ''PIGR'' gene. It is an Fc receptor which facilitates the transcytosis of the soluble polymeric isoforms of immunoglobulin A and immunoglobuli ...
;
PILRA
Paired immunoglobin like type 2 receptor alpha is a protein that in humans is encoded by the PILRA gene.
Function
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosp ...
;
PILRB
Paired immunoglobulin-like type 2 receptor beta is a protein that in humans is encoded by the ''PILRB'' gene.
Function
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephos ...
;
PRODH2;
PSG1;
PSG10
Pregnancy-specific beta-1-glycoprotein 10 is a protein that in humans is encoded by the ''PSG10'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ' ...
;
PSG11;
PSG11s';
PSG2;
PSG3
Pregnancy-specific beta-1-glycoprotein 3 is a protein that in humans is encoded by the ''PSG3'' gene.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
{{gene-19-stub ...
;
PSG4;
PSG5
Pregnancy-specific beta-1-glycoprotein 5 is a protein that in humans is encoded by the ''PSG5'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''g ...
;
PSG6;
PSG7;
PSG8;
PSG9
Pregnancy-specific beta-1-glycoprotein 9 is a protein that in humans is encoded by the ''PSG9'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning '' ...
;
PTGFRN
Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the ''PTGFRN'' gene. PTGFRN has also been designated as CD315 ( cluster of differentiation 315).
Interactions
PTGFRN has been shown to interact with CD9 a ...
;
PTPN1L;
PVR;
PVRL1
Poliovirus receptor-related 1 (PVRL1), also known as nectin-1 and CD111 (formerly herpesvirus entry mediator C, HVEC) is a human protein of the immunoglobulin superfamily (IgSF), also considered a member of the nectins. It is a membrane protein ...
;
PVRL2
Poliovirus receptor-related 2 (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a human plasma membrane glycoprotein.
Function
This gene encodes a single-pass type I membrane glycoprotein with two Ig-lik ...
;
PVRL3
Nectin-3, also known as nectin cell adhesion molecule 3, is a protein that in humans is encoded by the ''NECTIN3'' gene.
Nectin-3 belongs to the family of immunoglobulin(Ig)-like cellular adhesion molecules involved in Ca2+-independent cellular ...
;
PVRL4;
SCN2B
Sodium channel subunit beta-2 is a protein that in humans is encoded by the ''SCN2B'' gene.
See also
* Sodium channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. ...
;
SCN3B
Sodium channel subunit beta-3 is a protein that in humans is encoded by the ''SCN3B'' gene. Two alternatively spliced variants, encoding the same protein, have been identified.
Function
Voltage-gated sodium channels are transmembrane glycoprote ...
;
SCN4B
Sodium channel β-subunit 4, also known as SCN4B or Naβ4, is an auxiliary sodium channel subunit that can alter the kinetics of sodium channels. The protein is encoded by the ''SCN4B'' gene. Mutations in the ''SCN4B'' are associated with long QT s ...
;
SEMA3D;
SIGLEC1;
SIGLEC10;
SIGLEC11;
SIGLEC12
Sialic acid-binding Ig-like lectin 12, or Siglec-XII, is a protein that in humans, is encoded by the ''SIGLEC12'' gene.
Sialic acid-binding immunoglobulin-like lectins ( SIGLECs) are a family of cell surface proteins belonging to the immunoglobul ...
;
SIGLEC14;
SIGLEC15;
SIGLEC6
Sialic acid-binding Ig-like lectin 6 is a protein that in humans is encoded by the ''SIGLEC6'' gene. The gene was originally named CD33L (CD33-like) due to similarities between these genes but later became known as OB-BP1 ( OB eptinbinding protei ...
;
SIGLEC7;
SIGLEC8;
SIGLEC9;
SIRPA;
SIRPB1;
SIRPD;
SIRPG;
SISP1;
SLAMF6
SLAM family member 6 is a protein that in humans is encoded by the ''SLAMF6'' gene.
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is ...
;
SLAMF7
SLAM family member 7 is a protein that in humans is encoded by the ''SLAMF7'' gene.
The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant plasma cells in multiple myeloma. In contrast to CD138 (the traditional ...
;
TAPBPL;
TCRA;
TCRB;
TIMD4
T-cell immunoglobulin and mucin domain containing 4 (TIMD-4) also known as T-cell membrane protein 4 (TIM-4) is a protein in humans that is encoded by the TIMD4 gene. TIM-4 genes are in mouse present on chromosome 11B1.1 and in humans on chromoso ...
;
TRA@
Female-specific protein transformer is a protein that in ''Drosophila melanogaster'' is encoded by the tra gene. Unlike the related tra2 protein, it is only produced in females.
The transformer protein controls female somatic sexual differe ...
;
TRAV20;
TRBC1;
TRBV19;
TRBV3-1;
TRBV5-4;
TRBV7-2;
TRDV2;
TREM1
Triggering receptor expressed on myeloid cells 1 (TREM1) an immunoglobulin (Ig) superfamily transmembrane protein that, in humans, is encoded by the TREM1' gene. TREM1 is constitutively expressed on the surface of peripheral blood monocytes and ne ...
;
TREM2
Triggering receptor expressed on myeloid cells 2 (TREM2) is a protein that in humans is encoded by the ''TREM2'' gene. TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia, which are immune cells ...
;
TREML1;
TREML2;
TREML4;
TRGV3;
TRGV5;
TRGV7;
TRGV9;
VCAM1
Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the ''VCAM1'' gene. VCAM-1 functions as a cell adhesion molecule.
Stru ...
;
VCAN;
VPREB1
Immunoglobulin iota chain is a protein that in humans is encoded by the ''VPREB1'' gene. VPREB1 has also recently been designated CD179A ( cluster of differentiation 179A).
Function
CD179a (VpreB) is a 126 aa-long polypeptide with apparent M ...
;
VPREB3;
VSIG1;
VSIG2;
VSIG4
V-set and immunoglobulin domain containing 4 is a protein that in humans is encoded by the VSIG4 gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ' ...
;
VSIG9;
VSIG10;
VSTM1;
VSTM2;
VTCN1
V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the ''VTCN1'' gene.
Function
B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the su ...
;
References
Protein domains
Single-pass transmembrane proteins
{{membrane-protein-stub