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TCRB
TCRB may refer to: Biology * T-cell receptor beta locus (TCRB, TCRb, TCR𝛽, Tcrb, Tcr𝛽), a location on the T-cell receptor * TRCB gene and protein, also known as the T cell receptor beta constant 1 (TCRB1, TRCBC1) * T-cell-rich B-cell lymphoma (TCRB, TCRB-NHL), a type of large-cell lymphoma Other uses * T Coronae Borealis (T CrB), a recurrent nova variable star system * TCR Benelux Series (TCR-B, TCR-BNL), a racing car championship See also * {{dab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T-cell Receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR. The TCR is composed of two different protein chains (that is, it is a hetero dimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a beta (β) chain (encoded by ''TRA'' and ''TRB'', respectively), whereas in 5% of T cells the TCR consists of gamma and delta (γ/δ) chains (encoded by '' TRG'' and '' TRD'', respectively). This ratio changes during ontogeny and in diseased states (such as leukemia). It also differs between species. Orthologues of the 4 loci have been mapped in various species. Each locus can produce a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Cell Receptor Beta Constant 1
T cell receptor beta constant 1 is a protein that in humans is encoded by the TRBC1 gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b .... References External links * {{gene-7-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Large-cell Lymphoma
The large-cell lymphomas have large cells. One classification system for lymphomas divides the diseases according to the size of the white blood cells that have turned cancerous. A large cell, in this context, has a diameter of 17 to 20 μm. Other groups of lymphomas in this system are the small-cell lymphomas and mixed-cell lymphomas. Types B cell Diffuse large B-cell lymphoma is the most common of the large-cell lymphomas. MeSH now classifies the phrase "large-cell lymphoma" under "Diffuse large B cell lymphoma". Many other B-cell lymphomas feature large cells: * Angiocentric lymphoma * Burkitt's lymphoma * Follicular large-cell lymphoma * Immunoblastic lymphoma * Intravascular large-cell lymphoma * Primary mediastinal B-cell lymphoma * T-cell–rich B-cell lymphoma * Primary splenic lymphoma (rare) * Primary central nervous system lymphomas, which are often diffuse large-B-cell lymphomas * Richter's transformation: Diffuse Large B-cell Variant *1) ABC subtype (common) * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Coronae Borealis
T Coronae Borealis (''T CrB''), is a recurring nova in the constellation Corona Borealis. It was first discovered in outburst in 1866 by John Birmingham, although it had been observed earlier as a 10th magnitude star. Description T CrB normally has a magnitude of about 10, which is near the limit of typical binoculars. It has been seen to outburst twice, reaching magnitude 2.0 on May 12, 1866 and magnitude 3.0 on February 9, 1946, although a more recent paper shows the 1866 outburst with a possible peak range of magnitude 2.5 ± 0.5. Even when at peak magnitude of 2.5, this recurrent nova is dimmer than about 120 stars in the night sky. It is sometimes nicknamed the ''Blaze Star''. 34. Unusual Stellar Spectra III: two emission-line star ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
