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Interstate 81 (I-81) is a north–south (physically northeast–southwest)
Interstate Highway The Dwight D. Eisenhower National System of Interstate and Defense Highways, commonly known as the Interstate Highway System, or the Eisenhower Interstate System, is a network of controlled-access highways that forms part of the National Hi ...
in the eastern part of the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
. Its southern terminus is at
I-40 Interstate 40 (I-40) is a major east–west transcontinental Interstate Highway in the southeastern and southwestern portions of the United States. At a length of , it is the third-longest Interstate Highway in the country, after I-90 and ...
in Dandridge, Tennessee; its northern terminus is on
Wellesley Island Wellesley Island is an island in Jefferson County, New York, the island is partially in the Town of Orleans and partially in the Town of Alexandria. History The island was named Wells Island but during his 1815 survey of the US-Canada borde ...
, New York at the
Canadian border The borders of Canada include: * To the south and west: An international boundary with the United States, forming the Canada–United States border, longest shared border in the world, ; (Informally referred as the 49th parallel north which make ...
, where the
Thousand Islands Bridge The Thousand Islands International Bridge () is an American-maintained international bridge system over the Saint Lawrence River connecting northern New York in the United States with southeastern Ontario in Canada. Constructed in 1937, with add ...
connects it to Highway 137 and ultimately to
Highway 401 King's Highway 401, commonly referred to as Highway 401 and also known by its official name as the Macdonald–Cartier Freeway or colloquially referred to as the four-oh-one, is a controlled-access 400-series highway in the Canadian provi ...
, the main
Ontario Ontario is the southernmost Provinces and territories of Canada, province of Canada. Located in Central Canada, Ontario is the Population of Canada by province and territory, country's most populous province. As of the 2021 Canadian census, it ...
freeway connecting
Detroit Detroit ( , ) is the List of municipalities in Michigan, most populous city in the U.S. state of Michigan. It is situated on the bank of the Detroit River across from Windsor, Ontario. It had a population of 639,111 at the 2020 United State ...
via
Toronto Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a p ...
to
Montreal Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cit ...
. The major metropolitan areas along the route of I-81 include the Tri-Cities of Tennessee;
Roanoke Roanoke may refer to: Places *Roanoke Colony, a former English colony that mysteriously disappeared *Roanoke Island, the location of the Roanoke colony in present-day North Carolina *Roanoke River, flowing through Virginia and North Carolina and ...
in
Virginia Virginia, officially the Commonwealth of Virginia, is a U.S. state, state in the Southeastern United States, Southeastern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States between the East Coast of the United States ...
;
Hagerstown Hagerstown is a city in Washington County, Maryland, United States, and its county seat. The population was 43,527 at the 2020 census. Hagerstown ranks as Maryland's sixth-most populous incorporated city and is the most populous city in the ...
in Maryland;
Harrisburg Harrisburg ( ; ) is the List of capitals in the United States, capital city of the Commonwealth (U.S. state), U.S. commonwealth of Pennsylvania and the county seat, seat of Dauphin County, Pennsylvania, Dauphin County. With a population of 50, ...
and the
Wyoming Valley The Wyoming Valley is a historic industrialized region of Northeastern Pennsylvania. The region is historically notable for its influence in helping fuel the American Industrial Revolution with its many anthracite coal mines. As a metropolitan ar ...
in
Pennsylvania Pennsylvania, officially the Commonwealth of Pennsylvania, is a U.S. state, state spanning the Mid-Atlantic (United States), Mid-Atlantic, Northeastern United States, Northeastern, Appalachian, and Great Lakes region, Great Lakes regions o ...
; and
Binghamton Binghamton ( ) is a city in the U.S. state of New York, and serves as the county seat of Broome County. Surrounded by rolling hills, it lies in the state's Southern Tier region near the Pennsylvania border, in a bowl-shaped valley at the con ...
and
Syracuse Syracuse most commonly refers to: * Syracuse, Sicily, Italy; in the province of Syracuse * Syracuse, New York, USA; in the Syracuse metropolitan area Syracuse may also refer to: Places * Syracuse railway station (disambiguation) Italy * Provi ...
in New York. I-81 largely traces the paths created down the length of the
Appalachian Mountains The Appalachian Mountains, often called the Appalachians, are a mountain range in eastern to northeastern North America. The term "Appalachian" refers to several different regions associated with the mountain range, and its surrounding terrain ...
through the
Great Appalachian Valley The Great Appalachian Valley, also called The Great Valley or Great Valley Region, is one of the major landform features of eastern North America. It is a gigantic trough, including a chain of valley lowlands, and the central feature of the Appal ...
by migrating animals,
indigenous peoples There is no generally accepted definition of Indigenous peoples, although in the 21st century the focus has been on self-identification, cultural difference from other groups in a state, a special relationship with their traditional territ ...
, and early settlers. It also follows a major corridor for troop movements during the
Civil War A civil war is a war between organized groups within the same Sovereign state, state (or country). The aim of one side may be to take control of the country or a region, to achieve independence for a region, or to change government policies.J ...
. These trails and roadways gradually evolved into US Route 11 (US 11); I-81 parallels much of the older US 11. Being mostly rural in nature, I-81 is heavily used as a trucking corridor and is often used as a bypass of busier and more congested Interstates to the east such as
I-95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from U.S. Route 1 (US 1) in Miami, Florida, north to the Houlton–Woodstock Border Crossing between Maine and the ...
; for this reason, it is also used heavily by
drug A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...
and
human trafficker Human trafficking is the act of recruiting, transporting, transferring, harboring, or receiving individuals through force, fraud, or coercion for the purpose of exploitation. This exploitation may include forced labor, sexual slavery, or oth ...
s, as it is less monitored by
law enforcement Law enforcement is the activity of some members of the government or other social institutions who act in an organized manner to enforce the law by investigating, deterring, rehabilitating, or punishing people who violate the rules and norms gove ...
than I-95. This led to the
Federal Bureau of Investigation The Federal Bureau of Investigation (FBI) is the domestic Intelligence agency, intelligence and Security agency, security service of the United States and Federal law enforcement in the United States, its principal federal law enforcement ag ...
(FBI) forming a taskforce to combat the issue in 2017. The I-81 Corridor Coalition, a six-state coalition, was organized to handle issues along I-81, such as truck traffic and
air pollution Air pollution is the presence of substances in the Atmosphere of Earth, air that are harmful to humans, other living beings or the environment. Pollutants can be Gas, gases like Ground-level ozone, ozone or nitrogen oxides or small particles li ...
; the commission meets annually. I-81 is part of the fastest route between the
capital Capital and its variations may refer to: Common uses * Capital city, a municipality of primary status ** Capital region, a metropolitan region containing the capital ** List of national capitals * Capital letter, an upper-case letter Econom ...
of the US (
Washington, D.C. Washington, D.C., formally the District of Columbia and commonly known as Washington or D.C., is the capital city and federal district of the United States. The city is on the Potomac River, across from Virginia, and shares land borders with ...
) and the capital of
Canada Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of coun ...
(
Ottawa Ottawa is the capital city of Canada. It is located in the southern Ontario, southern portion of the province of Ontario, at the confluence of the Ottawa River and the Rideau River. Ottawa borders Gatineau, Gatineau, Quebec, and forms the cor ...
).


Route description

I-81 is part of the National Highway System, a network of highways that are considered essential to the country's economy, defense, and mobility by the
Federal Highway Administration The Federal Highway Administration (FHWA) is a division of the United States Department of Transportation that specializes in highway transportation. The agency's major activities are grouped into two programs, the Federal-aid Highway Program a ...
(FHWA). , - , TN , , , - , VA , , , - , WV , , , - , MD , , , - , PA , , , - , NY , , , - , Total , ,


Tennessee

I-81 begins in Tennessee at
I-40 Interstate 40 (I-40) is a major east–west transcontinental Interstate Highway in the southeastern and southwestern portions of the United States. At a length of , it is the third-longest Interstate Highway in the country, after I-90 and ...
in Dandridge, a route that connects to
Knoxville Knoxville is a city in Knox County, Tennessee, United States, and its county seat. It is located on the Tennessee River and had a population of 190,740 at the 2020 United States census. It is the largest city in the East Tennessee Grand Division ...
to the west and
Asheville Asheville ( ) is a city in Buncombe County, North Carolina, United States. Located at the confluence of the French Broad and Swannanoa rivers, it is the county seat of Buncombe County. It is the most populous city in Western North Carolina a ...
to the east. I-81 meets I-26 and US 23, which go to
Kingsport Kingsport is a city in Sullivan and Hawkins counties in the U.S. state of Tennessee. It lies along the Holston River and had a population of 55,442 at the 2020 census. It is the largest city in the Kingsport–Bristol metropolitan area, w ...
and Johnson City. At milemarker 75, I-81 leaves Tennessee and enters Virginia.


Virginia

I-81 in Virginia is largely a rural route with brief concurrencies with
I-77 Interstate 77 (I-77) is a north–south Interstate Highway in the Eastern United States. It traverses diverse terrain, from the mountainous state of West Virginia to the rolling farmlands of North Carolina and Ohio. It largely supplants the ...
and
I-64 Interstate 64 (I-64) is an east–west Interstate Highway in the Eastern United States. Its western terminus is at I-70, U.S. Route 40 (US 40), and US 61 in Wentzville, Missouri. Its eastern terminus is at the Bowers Hill ...
. The route parallels the Appalachian Mountains for much of its route through Tennessee and Virginia, serving such cities as the
twin cities Twin cities are a special case of two neighboring cities or urban centres that grow into a single conurbation – or narrowly separated urban areas – over time. There are no formal criteria, but twin cities are generally comparable in stat ...
of Bristol,
Tennessee Tennessee (, ), officially the State of Tennessee, is a landlocked U.S. state, state in the Southeastern United States, Southeastern region of the United States. It borders Kentucky to the north, Virginia to the northeast, North Carolina t ...
and
Virginia Virginia, officially the Commonwealth of Virginia, is a U.S. state, state in the Southeastern United States, Southeastern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States between the East Coast of the United States ...
; Wytheville;
Roanoke Roanoke may refer to: Places *Roanoke Colony, a former English colony that mysteriously disappeared *Roanoke Island, the location of the Roanoke colony in present-day North Carolina *Roanoke River, flowing through Virginia and North Carolina and ...
; Christiansburg; Lexington; Staunton; Harrisonburg; and
Winchester Winchester (, ) is a City status in the United Kingdom, cathedral city in Hampshire, England. The city lies at the heart of the wider City of Winchester, a local government Districts of England, district, at the western end of the South Downs N ...
. In Harrisonburg, I-81 cuts through
James Madison University James Madison University (JMU, Madison, or James Madison) is a public university, public research university in Harrisonburg, Virginia, United States. Founded in 1908, the institution was renamed in 1938 in honor of the fourth president of the ...
. It parallels its older counterpart, US 11, for its entire length in Virginia.


West Virginia

I-81 briefly enters the Eastern Panhandle of West Virginia for about , serving the city of Martinsburg. The entire routing is in Berkeley County and serves the
Eastern WV Regional Airport Eastern West Virginia Regional Airport , also known as Shepherd Field, is a civilian-owned, public use airport located four nautical miles (5  mi, 7  km) south of the central business district of Martinsburg, a city in Berkeley C ...
. The
West Virginia West Virginia is a mountainous U.S. state, state in the Southern United States, Southern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States.The United States Census Bureau, Census Bureau and the Association of American ...
segment was completed in 1966 and there have been no realignments since.


Maryland

In
Maryland Maryland ( ) is a U.S. state, state in the Mid-Atlantic (United States), Mid-Atlantic region of the United States. It borders the states of Virginia to its south, West Virginia to its west, Pennsylvania to its north, and Delaware to its east ...
, the Interstate Highway runs from the
West Virginia West Virginia is a mountainous U.S. state, state in the Southern United States, Southern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States.The United States Census Bureau, Census Bureau and the Association of American ...
state line at the
Potomac River The Potomac River () is in the Mid-Atlantic (United States), Mid-Atlantic region of the United States and flows from the Potomac Highlands in West Virginia to Chesapeake Bay in Maryland. It is long,U.S. Geological Survey. National Hydrography D ...
in Williamsport north to the
Pennsylvania Pennsylvania, officially the Commonwealth of Pennsylvania, is a U.S. state, state spanning the Mid-Atlantic (United States), Mid-Atlantic, Northeastern United States, Northeastern, Appalachian, and Great Lakes region, Great Lakes regions o ...
state line near Maugansville. I-81 is the primary north–south Interstate Highway in Washington County, connecting
Hagerstown Hagerstown is a city in Washington County, Maryland, United States, and its county seat. The population was 43,527 at the 2020 census. Hagerstown ranks as Maryland's sixth-most populous incorporated city and is the most populous city in the ...
with
Chambersburg Chambersburg is a borough in and the county seat of Franklin County, in the South Central region of Pennsylvania, United States. It is in the Cumberland Valley, which is part of the Great Appalachian Valley, and north of Maryland and the Ma ...
and
Harrisburg Harrisburg ( ; ) is the List of capitals in the United States, capital city of the Commonwealth (U.S. state), U.S. commonwealth of Pennsylvania and the county seat, seat of Dauphin County, Pennsylvania, Dauphin County. With a population of 50, ...
to the north and Martinsburg,
Winchester Winchester (, ) is a City status in the United Kingdom, cathedral city in Hampshire, England. The city lies at the heart of the wider City of Winchester, a local government Districts of England, district, at the western end of the South Downs N ...
, and
Roanoke Roanoke may refer to: Places *Roanoke Colony, a former English colony that mysteriously disappeared *Roanoke Island, the location of the Roanoke colony in present-day North Carolina *Roanoke River, flowing through Virginia and North Carolina and ...
to the south. It is the shortest mainline Interstate in Maryland and contains the shortest portion of I-81 of all six states through which the Interstate highway passes. The Interstate was dedicated as Maryland Veterans Memorial Highway in 1987. I-81 passes through the state of Maryland at one of its narrowest points, the "Hub City" of
Hagerstown Hagerstown is a city in Washington County, Maryland, United States, and its county seat. The population was 43,527 at the 2020 census. Hagerstown ranks as Maryland's sixth-most populous incorporated city and is the most populous city in the ...
where it intersects with a large number of other routes, most notably
I-70 Interstate 70 (I-70) is a major east–west Interstate Highway in the United States that runs from I-15 near Cove Fort, Utah, to I-695 and Maryland Route 570 (MD 570) in Woodlawn, just outside Baltimore, Maryland. I-70 appr ...
.
Hagerstown Regional Airport Hagerstown Regional Airport (Richard A. Henson Field) is in Washington County, Maryland, Washington County, Maryland, five miles north of Hagerstown, Maryland and a half mile (800 m) from the Maryland/Pennsylvania border. The airport is off ...
is served by this Interstate Highway.


Pennsylvania

I-81 forms a major north–south corridor through the state of Pennsylvania, serving the boroughs of
Chambersburg Chambersburg is a borough in and the county seat of Franklin County, in the South Central region of Pennsylvania, United States. It is in the Cumberland Valley, which is part of the Great Appalachian Valley, and north of Maryland and the Ma ...
and
Carlisle Carlisle ( , ; from ) is a city in the Cumberland district of Cumbria, England. Carlisle's early history is marked by the establishment of a settlement called Luguvalium to serve forts along Hadrian's Wall in Roman Britain. Due to its pro ...
, where it meets the
Pennsylvania Turnpike The Pennsylvania Turnpike, sometimes shortened to Penna Turnpike or PA Turnpike, is a controlled-access toll road which is operated by the Pennsylvania Turnpike Commission (PTC) in Pennsylvania. It runs for across the southern part of the st ...
(
I-76 Interstate 76 or I-76 may refer to: Transportation * Interstate 76 (Colorado–Nebraska) (I-76), US * Interstate 76 (Ohio–New Jersey) (I-76), running through Pennsylvania, US Other uses * ''Interstate '76'', a vehicular combat video game for W ...
) but does not directly interchange with it (motorists must use US 11 to connect). Around the state capital of
Harrisburg Harrisburg ( ; ) is the List of capitals in the United States, capital city of the Commonwealth (U.S. state), U.S. commonwealth of Pennsylvania and the county seat, seat of Dauphin County, Pennsylvania, Dauphin County. With a population of 50, ...
, the route forms the northern section of Pennsylvania's
Capital Beltway The Capital Beltway, designated as Interstate 495 (I-495) for its entire length, is an List of auxiliary Interstate Highways, auxiliary Interstate Highway in the Washington metropolitan area. The Ring road, beltway encircles Washington, D.C., ...
. The route then travels northeast toward the
Wyoming Valley The Wyoming Valley is a historic industrialized region of Northeastern Pennsylvania. The region is historically notable for its influence in helping fuel the American Industrial Revolution with its many anthracite coal mines. As a metropolitan ar ...
, where it serves the cities of
Wilkes-Barre Wilkes-Barre ( , alternatively or ) is a city in Luzerne County, Pennsylvania, United States, and its county seat. Located at the center of the Wyoming Valley in Northeastern Pennsylvania, it had a population of 44,328 in the 2020 census. ...
and
Scranton Scranton is a city in and the county seat of Lackawanna County, Pennsylvania, United States. With a population of 76,328 as of the 2020 United States census, 2020 census, Scranton is the most populous city in Northeastern Pennsylvania and the ...
(as well as meeting the PA Turnpike's Northeast Extension), then heads north through the
Endless Mountains The Endless Mountains is a geographical, geological, and cultural region in Northeastern Pennsylvania. The Endless Mountains region includes Bradford County, Pennsylvania, Bradford, Sullivan County, Pennsylvania, Sullivan, Susquehanna County, Pe ...
region toward the state line.


New York

In New York, I-81 crosses the Pennsylvania state line southeast of
Binghamton Binghamton ( ) is a city in the U.S. state of New York, and serves as the county seat of Broome County. Surrounded by rolling hills, it lies in the state's Southern Tier region near the Pennsylvania border, in a bowl-shaped valley at the con ...
. The freeway runs north–south through
Central New York The central region of New York state includes: * Auburn in Cayuga County * Cortland in Cortland County * Oneida in Madison County * Syracuse, the largest city of Central New York, in Onondaga County * Fulton and Oswego in Oswego County ...
, serving the cities of Binghamton,
Syracuse Syracuse most commonly refers to: * Syracuse, Sicily, Italy; in the province of Syracuse * Syracuse, New York, USA; in the Syracuse metropolitan area Syracuse may also refer to: Places * Syracuse railway station (disambiguation) Italy * Provi ...
, and Watertown. It passes through the
Thousand Islands The Thousand Islands (, ) constitute a North American archipelago of 1,864 islands that straddles the Canada–US border in the Saint Lawrence River as it emerges from the northeast corner of Lake Ontario. They stretch for about downstream fr ...
in its final miles and crosses two bridges, both part of the series of bridges known as the
Thousand Islands Bridge The Thousand Islands International Bridge () is an American-maintained international bridge system over the Saint Lawrence River connecting northern New York in the United States with southeastern Ontario in Canada. Constructed in 1937, with add ...
. South of Watertown, I-81 closely parallels US 11, the main north–south highway in Central New York prior to the construction of I-81. At Watertown, US 11 turns northeastward to head across New York's
North Country North Country may refer to: Places * North Country, Cornwall, England * North Country, the northern third of New Hampshire, U.S. **Great North Woods Region (New Hampshire) *North Country (New York), a region of Upstate New York ** North Country Co ...
while I-81 continues on a generally northward track to the Canadian border. From there, the road continues into the province of
Ontario Ontario is the southernmost Provinces and territories of Canada, province of Canada. Located in Central Canada, Ontario is the Population of Canada by province and territory, country's most populous province. As of the 2021 Canadian census, it ...
as Highway 137, a short route leading north to the nearby
Highway 401 King's Highway 401, commonly referred to as Highway 401 and also known by its official name as the Macdonald–Cartier Freeway or colloquially referred to as the four-oh-one, is a controlled-access 400-series highway in the Canadian provi ...
.


History

I-81 roughly parallels the
Great Indian Warpath The Great Indian Warpath (GIW)—also known as the Great Indian War and Trading Path, or the Seneca Trail—was part of the network of trails in eastern North America developed and used by Native Americans in the United States, Native Americans w ...
, an old Indian trail that connected New York to the
Piedmont Piedmont ( ; ; ) is one of the 20 regions of Italy, located in the northwest Italy, Northwest of the country. It borders the Liguria region to the south, the Lombardy and Emilia-Romagna regions to the east, and the Aosta Valley region to the ...
region of the southeastern United States via Virginia and West Virginia. A series of roads linking Virginia to Maryland through Martinsburg were present on maps as early as 1873. New York was originally served by
New York State Route 2 New York State Route 2 (NY 2) is a state highway in the Capital District of New York in the United States. It extends for from an interchange with Interstate 87 (I-87) and NY 7 in the town of Colonie to the Massachusetts ...
(NY 2), a road built in 1924; NY 2 was replaced by US 11 in 1927. A highway that largely followed the path of US 11 was built and became known as the Penn-Can Highway. On August 14, 1957, the highway was redesigned as I-81. In New York, the first segments of what would become I-81 were begun in 1954. In Maryland, the Interstate was begun with the Hagerstown Bypass in the mid-1950s. After several bouts of expansion, the freeway was completed from US 40 (now
Maryland Route 144 Maryland Route 144 (MD 144) is a collection of state highways in the U.S. state of Maryland. These highways are sections of old alignment of U.S. Route 40 in Maryland, U.S. Route 40 (US 40) between Cumberland, Maryland, Cumberland and Baltimo ...
D 144 to the Pennsylvania state line in 1958 and marked as I-81 in 1959. Bidding on contracts in West Virginia opened in July 1958. In Virginia, the first Interstate hearing was held in February 1957. At the end of 1957, construction began on a stretch near
Buchanan, Virginia Buchanan ( ) is a town in Botetourt County, Virginia, United States. The population was 1,196 at the 2020 United States census, 2020 census. It is part of the Roanoke metropolitan area. It was the western terminus of the James River and Kanawha ...
. A section of the Interstate opened in 1959. A stretch in Harrisonburg was opened as well. By late 1963, in Virginia were open. The first statewide segment to be completed was that of West Virginia, which was finished in 1966. The section opened on October 19, 1966. In western Maryland, various parts of I-81 were built in the early 1960s, and the remainder of the highway south to the Potomac River was under construction by 1965 and opened in 1966. Since then, I-81 in Maryland has remained largely unchanged. In Tennessee by 1965, of the of Interstate Highways were completed. Construction was expected to be finished in 1969, but a large portion of the work would not be completed until 1974, and most of the road was open by December 1974. The final major segment of the Interstate in the north to be built was a section in New York, opened in October 1968. That same year, work in Pennsylvania was completed. The road would not be completely built in Tennessee until August 1975. Construction on parts in Virginia dragged on until it was finished in July 1987. The segment in New York cost $270 million (equivalent to $ in ) to build.


Major intersections

;Tennessee * near Dandridge, northeast of
Knoxville Knoxville is a city in Knox County, Tennessee, United States, and its county seat. It is located on the Tennessee River and had a population of 190,740 at the 2020 United States census. It is the largest city in the East Tennessee Grand Division ...
* at the
White Pine ''Pinus'', the pines, is a genus of approximately 111 extant tree and shrub species. The genus is currently split into two subgenera: subgenus ''Pinus'' (hard pines), and subgenus ''Strobus'' (soft pines). Each of the subgenera have been further ...
Morristown line * in Mosheim * in
Kingsport Kingsport is a city in Sullivan and Hawkins counties in the U.S. state of Tennessee. It lies along the Holston River and had a population of 55,442 at the 2020 census. It is the largest city in the Kingsport–Bristol metropolitan area, w ...
* in
Bristol Bristol () is a City status in the United Kingdom, cathedral city, unitary authority area and ceremonial county in South West England, the most populous city in the region. Built around the River Avon, Bristol, River Avon, it is bordered by t ...
;Virginia * in
Bristol Bristol () is a City status in the United Kingdom, cathedral city, unitary authority area and ceremonial county in South West England, the most populous city in the region. Built around the River Avon, Bristol, River Avon, it is bordered by t ...
. I-81/US 58 travels concurrently to east of Abingdon * in Bristol * in Bristol * east of Abingdon * at various locations * in Wytheville. I-81/US 52 travels concurrently to Fort Chiswell * in Wytheville. The highways travel concurrently to Fort Chiswell. * in Christiansburg * in
Roanoke Roanoke may refer to: Places *Roanoke Colony, a former English colony that mysteriously disappeared *Roanoke Island, the location of the Roanoke colony in present-day North Carolina *Roanoke River, flowing through Virginia and North Carolina and ...
* southeast of Lexington * east of Lexington. The highways travel concurrently to Staunton. * in Peyton * in Harrisonburg *
New Market New Market may refer to: Bangladesh *New Market, Dhaka *New Market, Khulna, in Sonadanga Model Thana *New Market, Chittagong, near Government City College, Chittagong India * New Market, Bhopal *New Market, Kolkata Jamaica *New Market, Jam ...
* southwest of Middletown * in
Winchester Winchester (, ) is a City status in the United Kingdom, cathedral city in Hampshire, England. The city lies at the heart of the wider City of Winchester, a local government Districts of England, district, at the western end of the South Downs N ...
;West Virginia * north-northeast of Falling Waters ;Maryland * in Williamsport * in Halfway * in
Hagerstown Hagerstown is a city in Washington County, Maryland, United States, and its county seat. The population was 43,527 at the 2020 census. Hagerstown ranks as Maryland's sixth-most populous incorporated city and is the most populous city in the ...
;Pennsylvania *
Chambersburg Chambersburg is a borough in and the county seat of Franklin County, in the South Central region of Pennsylvania, United States. It is in the Cumberland Valley, which is part of the Great Appalachian Valley, and north of Maryland and the Ma ...
* north of Enola * in
Harrisburg Harrisburg ( ; ) is the List of capitals in the United States, capital city of the Commonwealth (U.S. state), U.S. commonwealth of Pennsylvania and the county seat, seat of Dauphin County, Pennsylvania, Dauphin County. With a population of 50, ...
. I-81/US 322 concurrent throughout Harrisburg. * in Harrisburg * near
Jonestown The Peoples Temple Agricultural Project, better known by its informal name "Jonestown", was a remote settlement in Guyana established by the Peoples Temple, an American religious movement under the leadership of Jim Jones. Jonestown became in ...
* west of Tremont * near Hazleton * in
Dupont Dupont, DuPont, Du Pont, duPont, or du Pont may refer to: People * Dupont (surname) Dupont, also spelled as DuPont, duPont, Du Pont, or du Pont is a French surname meaning "of the bridge", historically indicating that the holder of the surname re ...
(near
Pittston Pittston is a city in Luzerne County, Pennsylvania, United States. The city lies in the Wyoming Valley on the east side of the Susquehanna River and on the south side of the Lackawanna River. It is approximately midway between Wilkes-Barre, Pen ...
) * in
Dunmore Dunmore from the or , meaning "great fort", may refer to: People * Dunmore (surname) * Earl of Dunmore, a title in the Peerage of Scotland, includes a list of earls * Countess of Dunmore (disambiguation), a list of wives of earls of Dunmore Pl ...
* in Clarks Summit ;New York * in
Binghamton Binghamton ( ) is a city in the U.S. state of New York, and serves as the county seat of Broome County. Surrounded by rolling hills, it lies in the state's Southern Tier region near the Pennsylvania border, in a bowl-shaped valley at the con ...
* in Binghamton * in LaFayette * in
Syracuse Syracuse most commonly refers to: * Syracuse, Sicily, Italy; in the province of Syracuse * Syracuse, New York, USA; in the Syracuse metropolitan area Syracuse may also refer to: Places * Syracuse railway station (disambiguation) Italy * Provi ...
* in Syracuse * in North Syracuse * in
Cicero Marcus Tullius Cicero ( ; ; 3 January 106 BC – 7 December 43 BC) was a Roman statesman, lawyer, scholar, philosopher, orator, writer and Academic skeptic, who tried to uphold optimate principles during the political crises tha ...
* in
Adams Adams may refer to: * For persons, see Adams (surname) Places United States *Adams, California *Adams, California, former name of Corte Madera, California * Adams, Decatur County, Indiana *Adams, Kentucky *Adams, Massachusetts, a New England to ...
* in Watertown * ; freeway ends at Canada–US border (
Thousand Islands Bridge The Thousand Islands International Bridge () is an American-maintained international bridge system over the Saint Lawrence River connecting northern New York in the United States with southeastern Ontario in Canada. Constructed in 1937, with add ...
)


Auxiliary routes

I-81 has six related,
auxiliary Interstate Highway Auxiliary Interstate Highways (also called three-digit Interstate Highways) are a subset of highways within the United States' Interstate Highway System. The 323 auxiliary routes generally fall into three types: spur routes, which connect to or i ...
s that connect the main freeway to downtowns and other cities. I-381 runs , connecting
Bristol, Virginia Bristol is an independent city (United States), independent city in the Commonwealth (U.S. state), Commonwealth of Virginia. As of the 2020 United States census, 2020 census, the population was 17,219. It is the Twin cities (geographical proxi ...
, to I-81. I-581 is a spur that connects
Roanoke, Virginia Roanoke ( ) is an Independent city (United States), independent city in Virginia, United States. It lies in Southwest Virginia, along the Roanoke River, in the Blue Ridge Mountains, Blue Ridge range of the greater Appalachian Mountains. Roanok ...
, to I-81. It is proposed to be overtaken by
I-73 Interstate 73 (I-73) is a north–south Interstate Highway, currently located entirely within the US state of North Carolina. It travels , from northwest of Rockingham, North Carolina to northeast of Stokesdale, providing a freeway connec ...
.
Pennsylvania Route 581 The Capital Beltway is a ring road, beltway surrounding Harrisburg, Pennsylvania, Harrisburg, Pennsylvania, in the United States. It is concurrency (road), co-designated as Interstate 81 in Pennsylvania, Interstate 81 (I-81), Interstate 83 ...
(PA 581) connects
Harrisburg, Pennsylvania Harrisburg ( ; ) is the capital city of the U.S. commonwealth of Pennsylvania and the seat of Dauphin County. With a population of 50,099 as of 2020, Harrisburg is the ninth-most populous city in Pennsylvania. It is the larger of the two pr ...
, to I-81. It runs . I-481 serves as an eastern bypass of
Syracuse, New York Syracuse ( ) is a City (New York), city in and the county seat of Onondaga County, New York, United States. With a population of 148,620 and a Syracuse metropolitan area, metropolitan area of 662,057, it is the fifth-most populated city and 13 ...
.
NY 481 New York State Route 481 (NY 481) is a List of State Routes in New York, state highway in Central New York in the United States. The southern terminus of the route is at an interchange with Interstate 81 in New York, Interstate 81 ...
is a northwestern extension of I-481 that ends in Oswego. I-781 extends for , that connects
Fort Drum, New York Fort Drum is a U.S. Army military reservation and a census-designated place (CDP) in Jefferson County, near the western border of northern New York, United States. The population of the CDP portion of the base was 12,955 at the 2010 census. ...
, to the Interstate. NY 281 is a north–south
state highway A state highway, state road, or state route (and the equivalent provincial highway, provincial road, or provincial route) is usually a road that is either Route number, numbered or maintained by a sub-national state or province. A road numbered ...
in
Central New York The central region of New York state includes: * Auburn in Cayuga County * Cortland in Cortland County * Oneida in Madison County * Syracuse, the largest city of Central New York, in Onondaga County * Fulton and Oswego in Oswego County ...
in the US that extends for across Cortland and
Onondaga Onondaga may refer to: Native American/First Nations * Onondaga people, a Native American/First Nations people and one of the five founding nations of the Iroquois League * Onondaga (village), Onondaga settlement and traditional Iroquois capit ...
counties, roughly paralleling I-81 and connecting at both ends. I-181 was a offshoot of I-81, linking to
Kingsport, Tennessee Kingsport is a city in Sullivan and Hawkins counties in the U.S. state of Tennessee. It lies along the Holston River and had a population of 55,442 at the 2020 census. It is the largest city in the Kingsport–Bristol metropolitan area, ...
. It was decommissioned in August 2005 when I-26 took over I-181's entire length. I-281 was replaced in January 1970 by I-481. I-81E was replaced by the current
I-380 Interstate 380 may refer to: * Interstate 380 (California), a spur from Interstate 280 to U.S. Route 101 and the San Francisco International Airport * Interstate 380 (Iowa), a spur from Interstate 80 that starts in Iowa City and eventually ends ...
.


References


External links

*
Thousand Islands Bridge System
showing the bridges and connections at the northern terminus

a Federal Highway Administration report. {{Authority control 81