5-Ethoxy-DMT
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5-Ethoxy-DMT (5-ethoxy-''N'',''N''-dimethyltryptamine, 5-EtO-DMT, ''O''-ethylbufotenine) is a
tryptamine Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
derivative In mathematics, the derivative is a fundamental tool that quantifies the sensitivity to change of a function's output with respect to its input. The derivative of a function of a single variable at a chosen input value, when it exists, is t ...
which has been previously synthesized as a chemical intermediate, but has not been studied to determine its pharmacology. The widespread recreational use of ''N'',''N''-dialkylated
5-methoxytryptamine 5-Methoxytryptamine (5-MT, 5-MeO-T, or 5-OMe-T), also known as serotonin methyl ether or ''O''-methylserotonin and as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. It has been shown to oc ...
derivatives including
5-MeO-DMT 5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by ...
,
5-MeO-MiPT 5-MeO-MiPT is a psychedelic and hallucinogen of the tryptamine family. It used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs 5-MeO-DiPT, DiPT, and MiPT. It is commonly used as a "substitute" for ...
and
5-MeO-DiPT 5-MeO-DiPT, also known as 5-methoxy-''N'',''N''-diisopropyltryptamine and sometimes as foxy methoxy or simply foxy, is a psychedelic drug of the tryptamine and 5-methoxytryptamine families. It is the 5-methoxy derivative of diisopropyltryptami ...
has led to concern that the 5-ethoxy
homologs Homologous chromosomes or homologs are a set of one maternal and one paternal chromosome that pair up with each other inside a cell during meiosis. Homologs have the same genes in the same loci, where they provide points along each chromosome th ...
of these drugs could emerge as novel
designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...
s, and consequently 5-EtO-DMT and other derivatives including 5-EtO-DET, 5-EtO-DPT, 5-EtO-DiPT, 5-EtO-DALT, 5-EtO-MPT, 5-EtO-MiPT, 5-EtO-EiPT, 5-EtO-MET and 5-EtO-EPT have been synthesized as
analytical standards Analytic or analytical may refer to: Chemistry * Analytical chemistry, the analysis of material samples to learn their chemical composition and structure * Analytical technique, a method that is used to determine the concentration of a chemical ...
in order to facilitate future research into these compounds.


See also

*
5-Allyloxy-AMT 5-Allyloxy-AMT, also known as 5-allyloxy-α-methyltryptamine, is a serotonin 5-HT2 receptor agonist of the tryptamine, 5-alkyloxytryptamine, and α-alkyltryptamine families. It is known to act as high-efficacy partial agonist or near-full agon ...
*
5-Benzyloxytryptamine 5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors, and an antagonist of TRPM8. Legality 5-Benzyloxytryptamine is illegal in Singapore. See also * 5-Carboxa ...
* 5-EtO-AMT * 5-Ethyl-DMT *
5-(Nonyloxy)tryptamine 5-(Nonyloxy)tryptamine (5-NOT) is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length in this series gives generally increasing potency and selectivity for 5-HT1B, with highest a ...
*
O-Acetylbufotenine ''O''-Acetylbufotenine, or bufotenine ''O''-acetate, also known as 5-acetoxy-''N'',''N''-dimethyltryptamine (5-AcO-DMT) or ''O''-acetyl-''N'',''N''-dimethylserotonin, is a synthetic tryptamine derivative and putative serotonergic psychedelic. It ...


References

N,N-Dialkyltryptamines Dimethylamino compounds Ethoxy compounds 5-Methoxytryptamines {{pharmacology-stub