|
Thioescaline
Thioescaline (TE) is a pair of lesser-known psychedelic drugs with the chemical formula C12H19NO2S. They structural analogs of escaline in which an oxygen atom has been replaced with a sulfur atom. They were first synthesized by Alexander Shulgin and reported in his book '' PiHKAL''. Very little is known about their dangers or toxicity. See also * Thiomescaline * TME (psychedelics) * Thiotrisescaline Thiotrisescaline (T-TRIS) is a series of lesser-known phenethylamines prepared as potential Psychedelics, dissociatives and deliriants, psychedelic drugs. There are two isomers, 3-T-TRIS and 4-T-TRIS, each similar in structure to trisescaline with ... References {{reflist Psychedelic phenethylamines Thioethers Methoxy compounds Ethoxy compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiomescaline
Thiomescaline (TM) is a pair of lesser-known psychedelic drugs with the molecular formula C11H17NO2S. 3-TM and 4-TM are analogs of mescaline in which an oxygen atom has been replaced with a sulfur atom. They were first synthesized by Alexander Shulgin and described in his book '' PiHKAL''. Very little data exists on the pharmacological properties, metabolism, and toxicity of thiomescaline. 3-TM ''Dosage'': 60–100 mg ''Duration'': 8–12 hours ''Effects'': strong open and closed-eye visuals, synesthesia upon listening to music, +++ on the Shulgin Rating Scale 4-TM ''Dosage'': 20–40 mg ''Duration'': 10–15 hours ''Effects'': LSD-like imagery and effects See also * Thioescaline Thioescaline (TE) is a pair of lesser-known psychedelic drugs with the chemical formula C12H19NO2S. They structural analogs of escaline in which an oxygen atom has been replaced with a sulfur atom. They were first synthesized by Alexander Shulgin ... References {{reflist Psychede ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychedelics, Dissociatives And Deliriants
Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants. However, certain hallucinogens such as Fly agaric as well as other gabaergic hallucinogenics are more often considered to technically be hypnotics, therefore indicating another separate subcategory of drugs which can substantially alter visual perception. Etymology The word ''hallucinogen'' is derived from the word ''hallucination''. The term ''hallucinate'' dates back to around 1595–1605, and is derived from the Latin ''hallūcinātus'', the past participle of ''(h)allūcināri'', meaning "to wander in the mind." Characteristics Leo Hollister gave five criteria for classifying a drug as hallucinogenic.Glennon RA. Classical drugs: an introductory overview. In Lin GC and G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structural Analog
A structural analog (analogue in modern traditional English; Commonwealth English), also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced with other atoms, groups, or substructures. A structural analog can be imagined to be formed, at least theoretically, from the other compound. Structural analogs are often isoelectronic. Despite a high chemical similarity, structural analogs are not necessarily functional analogs and can have very different physical, chemical, biochemical, or pharmacological properties. In drug discovery, either a large series of structural analogs of an initial lead compound are created and tested as part of a structure–activity relationship study or a database is screened for structural analogs of a lead compound. Chemical analogues of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Escaline
Escaline (3,5-methoxy-4-ethoxyphenethylamine) is a psychedelic drug and entheogen of the phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues that included escaline, proscaline, and isoproscaline. The effects of this and related mescaline analogues in humans were first described by Alexander Shulgin. In his book ''PiHKAL, PiHKAL (Phenethylamines i Have Known And Loved)'', Shulgin lists the dosage range as 40 to 60 mg, consumed orally. The duration of action was stated to be 8–12 hours. Escaline is the phenethylamine analog of 3C-E and the 4-ethoxy analog of mescaline. Legal status Escaline is illegal in Sweden as of 26 January 2016. Escaline is a Schedule I controlled substance (DEA #7930) in the United States as it is a positional isomer of TMA (3,4,5-trimethoxyamphetamine). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamphetamine (MDMA, commonly known as "ecstasy") to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential. In 1991 and 1997, he and his wife Ann Shulgin compiled the books '' PiHKAL'' and '' TiHKAL'' (standing for ''Phenethylamines'' and ''Tryptamines I Have Known And Loved''), from notebooks that extensively described their work and personal experiences with these two classes of psychoactive drugs. Shulgin performed seminal work into the descriptive synthesis of many of these compounds. Some of Shulgin's noteworthy discoveries include compounds of the 2C* family (such as 2C-B) and compounds o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Music
Music is generally defined as the The arts, art of arranging sound to create some combination of Musical form, form, harmony, melody, rhythm or otherwise Musical expression, expressive content. Exact definition of music, definitions of music vary considerably around the world, though it is an aspect of all human societies, a cultural universal. While scholars agree that music is defined by a elements of music, few specific elements, there is Elements of music#Selection of elements, no consensus on their precise definitions. The creation of music is commonly divided into musical composition, musical improvisation, and musical performance, though the topic itself extends into #Academic study, academic disciplines, Music journalism, criticism, Philosophy of music, philosophy, and Music psychology, psychology. Music may be performed or improvised using a vast range of musical instrument, instruments, including the human voice. In some musical contexts, a performance or composi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pitch (music)
Pitch is a perceptual property of sounds that allows their ordering on a frequency-related scale, or more commonly, pitch is the quality that makes it possible to judge sounds as "higher" and "lower" in the sense associated with musical melodies. Pitch is a major auditory attribute of musical tones, along with duration, loudness, and timbre. Pitch may be quantified as a frequency, but pitch is not a purely objective physical property; it is a subjective psychoacoustical attribute of sound. Historically, the study of pitch and pitch perception has been a central problem in psychoacoustics, and has been instrumental in forming and testing theories of sound representation, processing, and perception in the auditory system. Perception Pitch and frequency Pitch is an auditory sensation in which a listener assigns musical tones to relative positions on a musical scale based primarily on their perception of the frequency of vibration. Pitch is closely related to frequency, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time
Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, to compare the duration of events or the intervals between them, and to quantify rates of change of quantities in material reality or in the conscious experience. Time is often referred to as a fourth dimension, along with three spatial dimensions. Time has long been an important subject of study in religion, philosophy, and science, but defining it in a manner applicable to all fields without circularity has consistently eluded scholars. Nevertheless, diverse fields such as business, industry, sports, the sciences, and the performing arts all incorporate some notion of time into their respective measuring systems. 108 pages. Time in physics is operationally defined as "what a clock reads". The physical nature of time is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conversation
Conversation is interactive communication between two or more people. The development of conversational skills and etiquette is an important part of socialization. The development of conversational skills in a new language is a frequent focus of language teaching and learning. Conversation analysis is a branch of sociology which studies the structure and organization of human interaction, with a more specific focus on conversational interaction. Definition and characterization No generally accepted definition of conversation exists, beyond the fact that a conversation involves at least two people talking together. Consequently, the term is often defined by what it is not. A ritualized exchange such as a mutual greeting is not a conversation, and an interaction that includes a marked status differential (such as a boss giving orders) is also not a conversation. An interaction with a tightly focused topic or purpose is also generally not considered a conversation. Summariz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shulgin Rating Scale
The Shulgin Rating Scale (or "quantitative potency scale") is a simple scale for reporting the subjective effect of psychoactive substances at a given dosage, and at a given time. The system was developed for research purposes by the American biochemist Alexander Shulgin, and published with co-authors Ann Shulgin and Peyton Jacob, III, in a 1986 issue of the journal ''Methods and Findings in Experimental and Clinical Pharmacology''. It was later described in the Shulgins' popular 1991 book ''PIHKAL: A Chemical Love Story''. ''PIHKAL'' Glossary excerpts Usage ''Shulgin Ratings'' typically include three components. An identification of the chemical being ingested, a dosage, and a descriptive narrative including the ratings themselves used to describe various moments in time. The chemical itself must be clearly identified, preferably using chemical nomenclature, as opposed to popular or "street" names. The dosage must be known and communicated, as substances may result in wildly diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TME (psychedelics)
TME, or thio metaescaline, is a series of lesser-known psychedelic drugs similar in structure to mescaline. Their structures are based on that of metaescaline. They were first synthesized by Alexander Shulgin and recorded in his book '' PiHKAL (Phenethylamines i Have Known And Loved)''. Very little is known about their dangers or toxicity. TME compounds {, , style="width: 1px; vertical-align: top" , : ''Dosage'': 60–100 mg : ''Duration'': 10–15 hours : ''Effects'': Strong entheogenic action, reduction of inhibition , style="width: 1px; vertical-align: top" , : ''Dosage'': 60–100 mg : ''Duration'': 10–15 hours : ''Effects'': Few to none , style="width: 1px; vertical-align: top" , {{clear : ''Dosage'': greater than 200 mg : ''Duration'': unknown : ''Effects'': Few to none See also * Phenethylamine * Psychedelics, dissociatives and deliriants * PiHKAL * Mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
