TME, or
thio metaescaline, is a series of lesser-known
psychedelic drugs
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science ...
similar in structure to
mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
Biological ...
. Their structures are based on that of
metaescaline. They were first synthesized by
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamp ...
and recorded in his book ''
PiHKAL (Phenethylamines i Have Known And Loved)''. Very little is known about their dangers or toxicity.
TME compounds
{,
, style="width: 1px; vertical-align: top" ,
: ''Dosage'': 60–100 mg
: ''Duration'': 10–15 hours
: ''Effects'': Strong
entheogen
Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoact ...
ic action, reduction of
inhibition
Inhibitor or inhibition may refer to:
In biology
* Enzyme inhibitor, a substance that binds to an enzyme and decreases the enzyme's activity
* Reuptake inhibitor, a substance that increases neurotransmission by blocking the reuptake of a neurotra ...
, style="width: 1px; vertical-align: top" ,
: ''Dosage'': 60–100 mg
: ''Duration'': 10–15 hours
: ''Effects'': Few to none
, style="width: 1px; vertical-align: top" ,
{{clear
: ''Dosage'': greater than 200 mg
: ''Duration'': unknown
: ''Effects'': Few to none
See also
*
Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace am ...
*
Psychedelics, dissociatives and deliriants
Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized ...
*
PiHKAL
*
Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
Biological ...
*
Metaescaline
External links
3-TME entry in ''PiHKAL''3-TME entry in PiHKAL • info4-TME entry in ''PiHKAL''4-TME entry in PiHKAL • info5-TME entry in ''PiHKAL''5-TME entry in PiHKAL • info
Psychedelic phenethylamines
Methoxy compounds
Thioethers
Ethoxy compounds