Thiotrisescaline (T-TRIS) is a series of lesser-known

phenethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace ami ...

s prepared as potential

psychedelic drugs Psychedelics are a subclass of Hallucinogen, hallucinogenic drugs whose primary effect is to trigger psychoactive drug, non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also ...

. There are two

isomer In chemistry, isomers are molecules or polyatomic ions with identical molecular formula – that is, the same number of atoms of each element (chemistry), element – but distinct arrangements of atoms in space. ''Isomerism'' refers to the exi ...

s, 3-T-TRIS and 4-T-TRIS, each similar in structure to

trisescaline Trisescaline (3,4,5-triethoxyphenethylamine) is a lesser-known phenethylamine prepared as a possible psychedelic drug. It is an analog of mescaline. Trisescaline was first synthesized by Alexander Shulgin. In his book ''PiHKAL'', both the minimum ...

with a sulfur atom in a place of a different oxygen atom. They were first synthesized by

Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and ph ...

and described in his book ''

PiHKAL ''PiHKAL: A Chemical Love Story'' is a book by Alexander Shulgin and Ann Shulgin published in 1991. The subject of the work is Psychoactive drug, psychoactive phenethylamine Derivative (chemistry), chemical derivatives, notably those that act ...

''.4-T-TRIS entry in ''PiHKAL''
/ref> Very little is known about their dangers or toxicity.

T-TRIS compounds

References

{{Phenethylamines Phenol ethers Scalines Thioethers

T-TRIS compounds

See also

References