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Schumanniophyton Problematicum
''Schumanniophyton problematicum'' is a species of plant in the family Rubiaceae. It is found in Ivory Coast, Ghana, and Sierra Leone. It is threatened by habitat loss. Chemistry The plant has been found to contain the alkaloids rohitukine and rohitukine ''N''-oxide, and the iridoid glycosides scyphiphorin A1–A2 and scyphiphorin B1–B2. Alvocidib is a synthetic analog of rohitukine that acts as a CDK9 kinase inhibitor and is under clinical development for the treatment of acute myeloid leukemia. It has also been studied for the treatment of arthritis and atherosclerotic plaque formation Rohitukine was initially extracted from ''Aphanamixis polystachya'' (the alkaloid name being derived from the synonym ''Amoora rohituka'') and later from ''Dysoxylum binectariferum ''Dysoxylum gotadhora'' is a tree in the family Meliaceae. It is native to Bhutan, India, Laos, Nepal, Thailand, and Vietnam. The name ''Dysoxylum ficiforme'' (Wight) Gamble in India and Sri Lanka ...
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Auguste Chevalier
Auguste may refer to: People Surname * Arsène Auguste (born 1951), Haitian footballer * Donna Auguste (born 1958), African-American businesswoman * Georges Auguste (born 1933), Haitian painter * Henri Auguste (1759–1816), Parisian gold and silversmith * Joyce Auguste, Saint Lucian musician * Jules Robert Auguste (1789–1850), French painter * Tancrède Auguste (1856–1913), President of Haiti (1912–13) Given name * Auguste, Baron Lambermont (1819–1905), Belgian statesman * Auguste, Duke of Leuchtenberg (1810–1835), prince consort of Maria II of Portugal * Auguste, comte de La Ferronays (1777–1842), French Minister of Foreign Affairs * Auguste Clot (1858–1936), French art printer * Auguste Dick (1910–1993), Austrian historian of mathematics * Georges Auguste Escoffier (1846–1935), French chef, restaurateur and culinary writer * Auguste Metz (1812–1854), Luxembourgian entrepreneur * Auguste Léopold Protet (1808–1862), French Navy admiral * Auguste ...
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Kinase Inhibitor
A protein kinase inhibitor is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that phosphorylate (add a phosphate, or PO4, group) to a protein and can modulate its function. The phosphate groups are usually added to serine, threonine, or tyrosine amino acids on the protein: most kinases act on both serine and threonine, the tyrosine kinases act on tyrosine, and a number (dual-specificity kinases) act on all three. There are also protein kinases that phosphorylate other amino acids, including histidine kinases that phosphorylate histidine residues. Phosphorylation regulates many biological processes, and protein kinase inhibitors can be used to treat diseases due to hyperactive protein kinases (including mutant or overexpressed kinases in cancer) or to modulate cell functions to overcome other disease drivers. Clinical use Kinase inhibitors such as dasatinib are often used in the treatment of cancer and inflammation. So ...
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Taxonomy Articles Created By Polbot
Taxonomy is the practice and science of categorization or classification. A taxonomy (or taxonomical classification) is a scheme of classification, especially a hierarchical classification, in which things are organized into groups or types. Among other things, a taxonomy can be used to organize and index knowledge (stored as documents, articles, videos, etc.), such as in the form of a library classification system, or a search engine taxonomy, so that users can more easily find the information they are searching for. Many taxonomies are hierarchies (and thus, have an intrinsic tree structure), but not all are. Originally, taxonomy referred only to the categorisation of organisms or a particular categorisation of organisms. In a wider, more general sense, it may refer to a categorisation of things or concepts, as well as to the principles underlying such a categorisation. Taxonomy organizes taxonomic units known as "taxa" (singular "taxon")." Taxonomy is different from ...
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Vulnerable Plants
Vulnerable may refer to: General * Vulnerability *Vulnerability (computing) * Vulnerable adult *Vulnerable species Music Albums * ''Vulnerable'' (Marvin Gaye album), 1997 * ''Vulnerable'' (Tricky album), 2003 * ''Vulnerable'' (The Used album), 2012 Songs * "Vulnerable" (Roxette song), 1994 * "Vulnerable" (Selena Gomez song), 2020 * "Vulnerable", a song by Secondhand Serenade from '' Awake'', 2007 * "Vulnerable", a song by Pet Shop Boys from ''Yes'', 2009 * "Vulnerable", a song by Tinashe from '' Black Water'', 2013 * "Vulnerability", a song by Operation Ivy from ''Energy'', 1989 Other uses * Climate change vulnerability, vulnerability to anthropogenic climate change In common usage, climate change describes global warming—the ongoing increase in global average temperature—and its effects on Earth's climate system. Climate change in a broader sense also includes previous long-term changes to ... used in discussion of society's response to climate change * ...
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Schumanniophyton
''Schumanniophyton'' is a genus of three species of small tree native to west Africa and belonging to the family Rubiaceae. It contains the following species and varieties: * ''Schumanniophyton hirsutum'' (Hiern) R.D.Good, native from W. Central Tropical Africa to N. Angola. * ''Schumanniophyton magnificum'' (K.Schum.) Harms Forest shrub or small tree, 12–16 ft. high, having soft-wooded stems bearing very large leaves. Flowers white or yellow, in a dense cluster subtended by broad bracts and borne at ends of shoots opposite a single leaf and just above a pair of leaves. Native from Nigeria to N. Angola. * ''Schumanniophyton magnificum'' var. ''klaineanum'' (Perre ex A.Chev.) N.Hallé, native to Gabon. * ''Schumanniophyton magnificum'' var. ''trimerum'' (R.D.Good) N.Hallé, native to W. Central Tropical Africa. * ''Schumanniophyton problematicum'', (A.Chev.) Aubrev. Forest tree 20–40 ft. high, having large deciduous leaves grouped in threes at the ends of the branches ...
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Scyphiphora Hydrophylacea
''Scyphiphora'' is a monotypic genus of flowering plants in the family Rubiaceae. It is the only genus in the tribe Scyphiphoreae. The genus contains only one species, viz. ''Scyphiphora hydrophylacea'', which has a large distribution range from India, to tropical Asia and the western Pacific. It is a shrub of about and is often found in mangrove forests or sandy beaches. Its local common names include ''nilad'' or ''sagasa'' in the Philippines, ''ngam'' in Thailand, ''côi'' in Vietnam, and ''chengam'' in Malaysia. Description Its leaves are opposite. The leaf blades are broad and drop-shaped. Its terminal buds and young leaves are coated with a varnish-like substance. The flowers are tubular and have four white lobes that are tinged pink. They are arranged in dense clusters. The fruits are elliptic and deeply ridged, becoming light brown and buoyant when ripe. Uses Its dark brown wood can be used to craft small objects. Leaf extracts are known to be helpful for stomach ache ...
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Meliaceae
Meliaceae, the mahogany family, is a flowering plant family of mostly trees and shrubs (and a few herbaceous plants, mangroves) in the order Sapindales. They are characterised by alternate, usually pinnate leaves without stipules, and by syncarpous, apparently bisexual (but actually mostly cryptically unisexual) flowers borne in panicles, cymes, spikes, or clusters. Most species are evergreen, but some are deciduous, either in the dry season or in winter. The family includes about 53 genera and about 600 known species, with a pantropical distribution; one genus ('' Toona'') extends north into temperate China and south into southeast Australia, another (''Synoum'') into southeast Australia, and another (''Melia'') nearly as far north. They most commonly grow as understory trees in rainforests, but are also found in mangroves and arid regions. The fossil record of the family extends back into the Late Cretaceous. Uses Various species are used for vegetable oil, soap-making, ...
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Dysoxylum
''Dysoxylum'' is a flowering plant genus of trees and shrubs from the mahogany family, Meliaceae. Botanical science has recorded about eighty species in this genus, growing widely across the regions of Malesia, the western Pacific ocean, Australia and south & southeastern Asia; centred on the tropics between the Pacific and Indian Oceans. They grow naturally in New Guinea, eastern and northern Australia, New Caledonia, Fiji, SE Asia, southern China, the Indian subcontinent, the Philippines, Taiwan, and in the western Pacific Ocean their most easterly occurrences, in the Caroline Islands, New Zealand and Niue. The etymology of its name ''Dysoxylum'' derives from the Greek word ‘''Dys''’ meaning "bad" referring to "ill-smelling" and ‘''Xylon''’ meaning "wood". Distribution New Guinea has records of twenty eight species growing naturally, sixteen of them endemic. New Caledonia has recorded nine, eight of them endemic. Fiji has recorded nine, seven of them endemic. I ...
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Aphanamixis Polystachya
''Aphanamixis polystachya'', the pithraj tree, is a species of tree in the family Meliaceae. It is native to India, Pakistan, Nepal, Bhutan, Bangladesh, Myanmar and Sri Lanka. It is a widely used as a medicinal plant in Ayurveda. Description The Bengali name of the tree is (). Another name of this tree is (). Oil is not edible and can be used as biodiesel and lighting. The very fine wood is used for construction and ship-making. The tree is 20m tall. Leaves are compound, imparipinnate, alternate; oblong-lanceolate, apex acuminate; base asymmetric; with entire margin. Flowers are polygamous and show panicles inflorescence. Fruit is a single seeded pale-reddish subglobose capsule. Common names *Assamese— *Bengali— *English—rohituka tree *Hindi— (), *Kannada—, , , *Khasi— *Kuki— *Malayalam—, *Manipuri— *Marathi— () *Rongmei— *Sanskrit—, , , , *Sinhala— *Tamil—, , *Telugu—, Chemistry The fruit shell contains triterpenes, aphanamixin. The bar ...
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Atherosclerotic Plaque
An atheroma, or atheromatous plaque, is an abnormal and reversible accumulation of material in the inner layer of an arterial wall. The material consists of mostly macrophage cells, or debris, containing lipids, calcium and a variable amount of fibrous connective tissue. The accumulated material forms a swelling in the artery wall, which may intrude into the lumen of the artery, narrowing it and restricting blood flow. Atheroma is the pathological basis for the disease entity atherosclerosis, a subtype of arteriosclerosis. Signs and symptoms For most people, the first symptoms result from atheroma progression within the heart arteries, most commonly resulting in a heart attack and ensuing debility. The heart arteries are difficult to track because they are small (from about 5 mm down to microscopic), they are hidden deep within the chest and they never stop moving. Additionally, all mass-applied clinical strategies focus on both minimal cost and the overall safety of ...
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Arthritis
Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. Onset can be gradual or sudden. There are over 100 types of arthritis. The most common forms are osteoarthritis (degenerative joint disease) and rheumatoid arthritis. Osteoarthritis usually occurs with age and affects the fingers, knees, and hips. Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. Other types include gout, lupus, fibromyalgia, and septic arthritis. They are all types of rheumatic disease. Treatment may include resting the joint and alternating between applying ice and heat. Weight loss and exercise may also be useful. Recommended medications may depend on the form of arthritis. These may include pain medications such as ibuprofen ...
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Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with haematopoiesis, normal blood cell production. Symptoms may include Fatigue, feeling tired, shortness of breath, Bruise, easy bruising and bleeding, and increased risk of infection. Occasionally, spread may occur to the brain, skin, or gums. As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. Risk factors include smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a anemia, drop in red blood cells, thrombocytopenia, platelets, and normal leukopenia, white blood cells. Diagnosis is generally based on bone marrow aspiration and specific blood tests. AML has several s ...
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