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Reshma Kewalramani
Reshma Kewalramani, is the president and chief executive officer of Vertex Pharmaceuticals, a biotechnology company based in Boston, Massachusetts, as of April 1, 2020. She is the first female CEO of a large US biotech company. She was previously the chief medical officer and vice president of global medicines development and medical affairs at Vertex. Early life and education Kewalramani was born in Bombay, India. She and her family immigrated to the US when she was 11 years old. She graduated in 1998 from the seven-year liberal arts/medical education program at Boston University, Phi Beta Kappa, Summa Cum Laude. She finished her internship and residency at the Massachusetts General Hospital and her fellowship in nephrology at the Massachusetts General Hospital and Brigham and Women's Hospital combined program. After finishing her fellowship in clinical nephrology she did research in transplantation. She graduated from the General Management Program at Harvard Business School ...
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Vertex Pharmaceuticals
Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in South Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, near Oxford, England. History Vertex was founded in 1989 by Joshua Boger and Kevin J. Kinsella . to ''"transform the way serious diseases are treated."'' The company's beginnings were profiled by Barry Werth in the 1994 book, ''The Billion-Dollar Molecule''. His 2014 book, ''The Antidote: Inside the World of New Pharma'', chronicled the company's subsequent development over the next two decades. By 2004, its product pipeline focused on viral infections, inflammatory and autoimmune disorders, and cancer. In 2009, the company had about 1,800 employees, including 1,200 in the Boston area. By 2019 there were about 2,500 employee ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ...
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American Women Chief Executives
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer ...
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American Women Scientists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the " United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soc ...
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New England Council
The New England Council is a regional business association representing both public and private organizations in the New England region of the United States. Established in 1925, it is the oldest regional business association in the United States. History A group of New England business leaders along with the states' six governors convened in Poland Spring, Maine in June 1925 to tackle issues related to economic growth in the region. This led to the first annual "New England Conference" later that year in Worcester, Massachusetts. According to the Council's own historical record, around "800 representatives of agricultural, industrial, and commercial organizations throughout New England" gathered during this conference to discuss "challenges facing the New England economy"; it was then that they decided to make the conference an annual event, and to establish the New England Council as the conference's executive body. The New England Council's success demonstrated that regional a ...
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Boston Business Journal
The ''Boston Business Journal'' is a weekly, business-oriented newspaper published in Boston, Massachusetts. It is published by the American City Business Journals. The newspaper was founded by Robert Bergenheim and launched its first issue on March 2, 1981. The newspaper was originally named "P&L The Boston Business Journal" ("P&L" stood for profit and loss). However, "P&L" was later dropped from the name. Bergenheim was a former publisher of the Boston Herald. Before that, he was an editor at ''The Christian Science Monitor ''The Christian Science Monitor'' (''CSM''), commonly known as ''The Monitor'', is a nonprofit news organization that publishes daily articles in electronic format as well as a weekly print edition. It was founded in 1908 as a daily newspaper ...''. See also * List of newspapers in Massachusetts References Business newspapers published in the United States Newspapers published in Boston 1981 establishments in Massachusetts Newspapers est ...
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American Society Of Nephrology
Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical research, and educates the renal community. ASN also informs policymakers about issues of importance to kidney doctors and their patients. Research and publications Each year, the ASN and the ASN Foundation for Kidney Research provide nearly 400 research and travel grants. ASN annual meetings are attended by approximately 13,000 participants, and regional meetings are held throughout the year. The society publishes the ''Journal of the American Society of Nephrology'' (JASN), the ''Clinical Journal of the American Society of Nephrology'' (CJASN), the ''Nephrology Self-Assessment Program'' (NephSAP), ''ASN Kidney News and Kidney News Online'', ''In The Loop'', and more recently the Kidney Self Assessment Program (KSAP). * ''JASN'' (1990–p ...
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American Medical Women's Association
The American Medical Women's Association (AMWA) is a professional advocacy and educational organization of women physicians and medical students. Founded in 1915 by Bertha Van Hoosen, the AMWA works to advance women in medicine and to serve as a voice for women's health. The association used to publish the ''Journal of the American Medical Women's Association''; the '' Journal of Women's Health'' is now the official journal of the AMWA. Honors The AMWA honors women physicians each year with four awards. * The Elizabeth Blackwell Medal, named for Elizabeth Blackwell, the first woman awarded an M.D. from an American medical school, is granted to "a woman physician who has made the most outstanding contributions to the cause of women in the field of medicine." * The Bertha Van Hoosen Award, named in honor of the Founder and first President of AMWA, honors "a woman physician who has demonstrated exceptional leadership and service to AMWA." * The Lila A. Wallis Award, named for one of ...
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American College Of Physicians
The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest medical-specialty organization and second-largest physician group in the United States, after the American Medical Association.Osmosis "Prep for the Medicine Shelf". Retrieved October 20, 2014 Its flagship journal, the ''Annals of Internal Medicine'', is considered one of the five top medical journals in the United States and Britain. Mission and history Founded in 1915, ACP's stated mission is to "enhance the quality and effectiveness of health care by fostering excellence and professionalism in the practice of medicine." In 1998, it merged with the American Society of Internal Medicine (ASIM). ASIM's focus on the economic, political, and social aspects of medical care both enlarged and complemented its mission. Known as ACP-ASIM from ...
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Ginkgo Bioworks
Ginkgo Bioworks is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications. Ginkgo Bioworks is an analytics company that designs microorganisms for customers in a range of industries. It is the self-proclaimed "Organism Company" and was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It raised $290 million in September and $350 million in October of that year. History In 2014, Ginkgo was the first biotechnology company to join the Y Combinator start-up accelerator program. On 16 December 2020, it was reported that Ginkgo Bioworks would acquire the primary assets of Novogy's Microbial Engineering Platform. 2020 also saw the company acquire property worth $25 million from Marcus Partners for the construction of a new 219,000 square foot laboratory building, after razing existing struc ...
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Boston University School Of Medicine
The Boston University Chobanian & Avedisian School of Medicine, formerly the Boston University School of Medicine, is one of the graduate schools of Boston University. Founded in 1848, the medical school was the first institution in the world to formally educate female physicians. Originally known as the New England Female Medical College, it was subsequently renamed Boston University School of Medicine in 1873, then Chobanian & Avedisian School of Medicine in 2022. In 1864, it became the first medical school in the United States to award an M.D. degree to an African-American woman. Chobanian & Avedisian School of Medicine is the only medical school located in the South End neighborhood of Boston, Massachusetts. Boston Medical Center, its primary teaching hospital, operates the largest 24-hour Level I trauma center in New England, and the largest network of regional community health centers. Chobanian & Avedisian School of Medicine is the home of the Framingham Heart Study, ...
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Beta Thalassemia
Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are forms of thalassemia caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals. Global annual incidence is estimated at one in 100,000. Beta thalassemias occur due to malfunctions in the hemoglobin subunit beta or HBB. The severity of the disease depends on the nature of the mutation. HBB blockage over time leads to decreased beta-chain synthesis. The body's inability to construct new beta-chains leads to the underproduction of HbA (adult hemoglobin). Reductions in HbA available overall to fill the red blood cells in turn leads to microcytic anemia. Microcytic anemia ultimately develops in respect to inadequate HBB protein for sufficient red blood cell functioning. Due to this factor, the patient may require blood transfusions to make up for the blockage in the beta-chains. Repeat ...
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