Periglandula
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Periglandula
Periglandula are a genus of fungi in the family Clavicipitaceae. Symbiosis They live as epibionts, in a symbiotic relationship with two species of plant, '' Ipomoea asarifolia'' and ''Ipomoea corymbosa''. They are known to produce ergot alkaloids related to lysergic acid such as ergine (lysergic acid amide; LSA), and LSH.Steiner, Ulrike, and Eckhard Leistner. "Ergoline alkaloids in convolvulaceous host plants originate from epibiotic clavicipitaceous fungi of the genus Periglandula." ''Fungal Ecology'' 5.3 (2012): 316-321. Available at/ref> See also *Ergot Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''. The most prominent member of this group is '' Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that c ... References External links * Clavicipitaceae Herbal and fungal hallucinogens Hypocreales genera Natural sources of lysergamides Psychedelic drugs Psychoacti ...
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Ergot
Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''. The most prominent member of this group is '' Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that can cause ergotism in humans and other mammals who consume grains contaminated with its fruiting structure (called ''ergot sclerotium''). ''Claviceps'' includes about 50 known species, mostly in the tropical regions. Economically significant species include ''C. purpurea'' (parasitic on grasses and cereals), ''C. fusiformis'' (on pearl millet, buffel grass), '' C. paspali'' (on dallis grass), ''C. africana'' (on sorghum) and ''C. lutea'' (on paspalum). ''C. purpurea'' most commonly affects outcrossing species such as rye (its most common host), as well as triticale, wheat and barley. It affects oats only rarely. ''C. purpurea'' has at least three races or varieties, which differ in their host specificity: *G1 – land grasses of op ...
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Ergine
Ergine, also known as lysergic acid amide (LSA or LAA) as well as LA-111, is a psychoactive compound of the ergoline and lysergamide families related to lysergic acid diethylamide (LSD). Ergine is an ergoline alkaloid found in fungi such as '' Claviceps paspali'' (ergot) and '' Periglandula'' species such as '' Periglandula clandestina'', which are permanently connected with many morning glory vines. Ergine induces relatively mild psychedelic effects as well as pronounced sedative effects. The most common sources of ergine for use as a drug are the seeds of morning glory species including ''Ipomoea tricolor'' (tlitliltzin), '' Ipomoea corymbosa'' (ololiuhqui), and '' Argyreia nervosa'' (Hawaiian baby woodrose). Morning glory seeds have a history of entheogenic use in Mesoamerica dating back at least hundreds of years. They have also since been used by many Westerners. In addition to ergine, morning glory seeds contain other ergolines such as lysergic acid hydroxyethylamid ...
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Ipomoea Asarifolia
''Ipomoea asarifolia'', known as the ginger-leaf morning-glory, is a species of plant in the family Convolvulaceae, of the genus ''Ipomoea''. Chemistry, toxicology, and pharmacology ''Ipomoea asarifolia'' lives symbiotically with the fungus ''Periglandula ipomoeae ''Periglandula ipomoeae'' is a fungus of the genus '' Periglandula'' in the family Clavicipitaceae. Symbiosis '' Ipomoea asarifolia'', and ''Ipomoea tricolor'' seeds contains LSA and LSH among other alkaloids, due to the presence of the symbiot ...'', which biosynthesizes ergoline alkaloids such as D-lysergic acid α-hyroxyethylamide as well as indole diterpene alkaloids. ''Periglandula ipomoeae'' was found on the following six organs: young leaves, mature leaves, flower buds, mature flowers, young seeds, and mature seeds. ''Ipomoea asarifolia'' causes a tremorgenic syndrome if ingested by '' Capra hircus'', but the reason for this is unknown. The effect has been attributed to tremorgenic phytotoxins or mycotoxi ...
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Ergot Alkaloid
Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous form. Even so, many ergoline alkaloids have been found to be clinically useful. Annual world production of ergot alkaloids has been estimated at 5,000–8,000 kg of all ergopeptines and 10,000–15,000 kg of lysergic acid, used primarily in the manufacture of semi-synthetic derivatives. Others, such as lysergic acid diethylamide, better known as LSD, a Semisynthesis, semi-synthetic derivative, and ergine, a natural derivative found in ''Argyreia nervosa'', ''Ipomoea tricolor'' and related species, are known Psychedelic drug, psychedelic substances. Natural occurrence Ergoline alkaloids are found in fungi such as Claviceps purpurea, Claviceps paspali, and the related Periglandula, which have a permanent, symbiotic bond with numerous ...
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Lysergic Acid Hydroxyethylamide
Lysergic acid hydroxyethylamide (LSH or LAH), also known as lysergic acid ''N''-(α-hydroxyethyl)amide, is an ergoamide and an ergoline. It is perhaps the main constituent of the parasitic fungus, '' Claviceps paspali''; and found in trace amounts in ''Claviceps purpurea''. ''C. paspali'' and ''C. purpurea'' are ergot-spreading fungi. ''Periglandula'', ''Clavicipitacepus'' fungi, are permanently symbiotically connected to an estimated 450species of ''Convolvulaceae'' and thus generate LAH in some of them (42 generate ergolines, by Eckart Eich's review). The most well-known ones are ''Ipomoea tricolor'' (“morning glory”), ''Turbina corymbosa'' (''coaxihuitl''), and '' Argyreia nervosa'' (Hawaiian baby woodrose). LAH is structurally similar to ergonovine, which is also known as lysergic acid hydroxymethylethylamide. The more well-known analog, lysergic acid amide (syn. ''ergine''), is more prominent in analytical results because LAH easily decomposes to ergine. Ergine is only ...
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Psychedelic Drugs
Psychedelics are a subclass of Hallucinogen, hallucinogenic drugs whose primary effect is to trigger psychoactive drug, non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like Salvia divinorum, salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, psychedelic visuals, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, Lysergic acid diethylamide, LSD, psilocybin, and N,N-Dimethyltryptamine, DMT. There are a large number of both natural product, naturally occurring and synthetic compound, synthetic serotonergic ...
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Genus
Genus (; : genera ) is a taxonomic rank above species and below family (taxonomy), family as used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In binomial nomenclature, the genus name forms the first part of the binomial species name for each species within the genus. :E.g. ''Panthera leo'' (lion) and ''Panthera onca'' (jaguar) are two species within the genus ''Panthera''. ''Panthera'' is a genus within the family Felidae. The composition of a genus is determined by taxonomy (biology), taxonomists. The standards for genus classification are not strictly codified, so different authorities often produce different classifications for genera. There are some general practices used, however, including the idea that a newly defined genus should fulfill these three criteria to be descriptively useful: # monophyly – all descendants of an ancestral taxon are grouped together (i.e. Phylogeneti ...
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Fungi
A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and mold (fungus), molds, as well as the more familiar mushrooms. These organisms are classified as one of the kingdom (biology)#Six kingdoms (1998), traditional eukaryotic kingdoms, along with Animalia, Plantae, and either Protista or Protozoa and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of motility, mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related o ...
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Clavicipitaceae
The Clavicipitaceae are a family (biology), family of fungi within the order Hypocreales. A 2008 estimate placed 43 genus, genera in the family, but a study in 2020 has increased this number to 50. Phylogeny Molecular phylogeny, phylogenetic analysis of multigene DNA sequence data indicates the taxon Clavicipitaceae (as circumscribed by 2007) is paraphyletic, and consists of three well-defined cladistics, clades, at least one of which is shared with members of another fungal family (Hypocreaceae). The most recent common ancestor of the three clades also include Hypocreaceae as a descendant. The issue seems to have been resolved in Sung ''et al.'' (2007b). Clavicipitaceae becomes restricted to "clade A". Cordycipitaceae is resurrected to hold "clade C". Ophiocordycipitaceae is created to hold "clade B". Evolution The evolution within the Clavicipitaceae (as circumscribed by 2007) is marked by interkingdom host jumping, and the range of this large and heterogeneous fungal grou ...
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Epibiont
An epibiont (from the Ancient Greek meaning "living on top of") is an organism that lives on the surface of another living organism, called the basibiont ("living underneath"). The interaction between the two organisms is called epibiosis. An epibiont is, by definition, harmless to its host. In this sense, the interaction between the two organisms can be considered neutralistic or commensalistic; as opposed to being, for example, parasitic, in which case one organism benefits at the expense of the other, or mutualistic, in which both organisms obtain some explicit benefit from their coexistence. These organisms have evolved various adaptations to exploit their hosts for protection, transportation, or access to resources. Examples of common epibionts are bacteria, barnacles, remoras, and algae, many of which live on the surfaces of larger marine organisms such as whales, sharks, sea turtles, and mangrove trees. Although there is no direct effect of the epibiont to the host, t ...
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Symbiosis
Symbiosis (Ancient Greek : living with, companionship < : together; and ''bíōsis'': living) is any type of a close and long-term biological interaction, between two organisms of different species. The two organisms, termed symbionts, can for example be in Mutualism (biology), mutualistic, commensalism, commensalistic, or parasitism, parasitic relationships. In 1879, Heinrich Anton de Bary defined symbiosis as "the living together of unlike organisms". The term is sometimes more exclusively used in a restricted, mutualistic sense, where both symbionts contribute to each other's subsistence. This means that they benefit each other in some way. Symbiosis can be ''obligate'' (or ''obligative''), which means that one, or both of the organisms depend on each other for survival, or ''facultative'' (optional), when they can also subsist independently. Symbiosis is also classified by physical attachment. Symbionts forming a single body live ...
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Ipomoea Corymbosa
''Ipomoea corymbosa'' (''Rivea corymbosa'', ''Turbina corymbosa'') is a species of morning glory, native throughout Latin America from Mexico as far south as Peru and widely naturalised elsewhere. Its common names include Christmasvine, Christmaspops, and snakeplant. Description and names Known to natives of north and central Mexico by its Nahuatl name, coaxihuitl and by the south eastern natives as xtabentún (in Mayan), it is a perennial climbing vine with white flowers, often grown as an ornamental plant. Its flowers secrete copious amount of nectar, and the honey that bees make from it is very clear and aromatic. It also grows in Cuba, where it usually blooms from early December to February. It is considered one of the main honey plants of the island. This plant is often used for purposes other than recreation, as natives of Mexico consider the flour produced from its seeds (distinguished as ''ololiuhqui'' (''ololiúqui'', "round things")) a tool for divination and communi ...
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