Moraxella Ovis
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Moraxella Ovis
''Moraxella'' is a genus of gram-negative bacteria in the family Moraxellaceae. It is named after the Swiss ophthalmology, ophthalmologist Victor Morax. The organisms are short Rod-shaped bacteria, rods, coccobacilli, or as in the case of ''Moraxella catarrhalis'', diplococci in morphology, with asaccharolytic, oxidase-positive, and catalase-positive properties.Ala'Aldeen, D. A. A. (2007). "Neisseria and moraxella". In Greenwood, David; Slack, Richard; Peitherer, John; & Barer, Mike (Eds.), ''Medical Microbiology'' (17th ed.), p. 258. Elsevier. . ''M. catarrhalis'' is the clinically most important species under this genus. Roles in disease The organisms are commensals of mucosal surfaces and sometimes give rise to opportunistic infection. * ''Moraxella catarrhalis, M. catarrhalis'' usually resides in respiratory tract, but can gain access to the lower respiratory tract in patients with chronic chest disease or compromised host defenses, thus causing tracheobronchitis and pneumoni ...
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Moraxella Atlantae
''Moraxella atlantae'' is a Gram-negative, oxidase-positive and catalase-positive, rod-shaped, nonmotile bacterium in the genus ''Moraxella''. First described in 1976 it was recognized as a rare opportunistic pathogen in humans starting in 1991. Taxonomy and microbiological characteristics ''Moraxella atlantae'' was first described as a new species in 1976 based on biochemical and microbiological culture , microbiological growth characteristics:Bøvre, K., et al. "Moraxella atlantae sp. nov. and its distinction from Moraxella phenylpyrouvica." International Journal of Systematic and Evolutionary Microbiology 26.4 (1976): 511-521. It resembled ''Moraxella phenylpyruvica'', but differed in "simultaneous lack of urease and phenylalanine and tryptophan deaminase activities, inability to grow on solid medium at 4 to 10°C, relative salt sensitivity, and different behaviour on bile-containing media." In difference it also contains n-octadecanol and mannose. It is a non-fermenter and ha ...
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Moraxella Saccharolytica
''Moraxella saccharolytica'' is a Gram-negative bacterium in the genus ''Moraxella'', which was isolated from the spinal cord of a child with meningitis Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasion .... References Moraxellaceae Bacteria described in 1956 {{Pseudomonadales-stub ...
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Lower Respiratory Tract
The respiratory tract is the subdivision of the respiratory system involved with the process of conducting air to the alveoli for the purposes of gas exchange in mammals. The respiratory tract is lined with respiratory epithelium as respiratory mucosa. Air is breathed in through the nose to the nasal cavity, where a layer of nasal mucosa acts as a filter and traps pollutants and other harmful substances found in the air. Next, air moves into the pharynx, a passage that contains the intersection between the oesophagus and the larynx. The opening of the larynx has a special flap of cartilage, the epiglottis, that opens to allow air to pass through but closes to prevent food from moving into the airway. From the larynx, air moves into the trachea and down to the intersection known as the carina that branches to form the right and left primary (main) bronchi. Each of these bronchi branches into a secondary (lobar) bronchus that branches into tertiary (segmental) bronchi, tha ...
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Opportunistic Infection
An opportunistic infection is an infection that occurs most commonly in individuals with an immunodeficiency disorder and acts more severe on those with a weakened immune system. These types of infections are considered serious and can be caused by a variety of pathogens including viruses, bacteria, fungi, and parasites. Under normal conditions, such as in humans with uncompromised immune systems, an opportunistic infection would be less likely to cause significant harm and would typically result in a mild infection or no effect at all. These opportunistic infections can stem from a variety of sources, such as a weakened immune system (caused by human immunodeficiency virus and acquired immunodeficiency syndrome), when being treated with immunosuppressive drugs (as in cancer treatment), when a microbiome is altered (such as a disruption in gut microbiota), or when integumentary barriers are breached (as in penetrating trauma). Opportunistic infections can contribute to antimic ...
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Catalase
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). Catalase has one of the highest turnover numbers of all enzymes; one catalase molecule can convert millions of hydrogen peroxide molecules to water and oxygen each second. Catalase is a tetramer of four polypeptide chains, each over 500 amino acids long. It contains four iron-containing heme groups that allow the enzyme to react with hydrogen peroxide. The optimum pH for human catalase is approximately 7, and has a fairly broad maximum: the rate of reaction does not change appreciably between pH 6.8 and 7.5. The pH optimum for other catalases varies between 4 and 11 depending on the species. The optimum temperature also varies by species. Structure Human catalase for ...
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Oxidase
In biochemistry, an oxidase is an oxidoreductase (any enzyme that catalyzes a redox reaction) that uses dioxygen (O2) as the electron acceptor. In reactions involving donation of a hydrogen atom, oxygen is reduced to water (H2O) or hydrogen peroxide (H2O2). Some oxidation reactions, such as those involving monoamine oxidase or xanthine oxidase, typically do not involve free molecular oxygen. The oxidases are a subclass of the oxidoreductases. The use of dioxygen is the only unifying feature; in the EC classification, these enzymes are scattered in many categories. Examples An important example is EC 7.1.1.9 cytochrome c oxidase, the key enzyme that allows the body to employ oxygen in the generation of energy and the final component of the electron transfer chain. Other examples are: * EC 1.1.3.4 Glucose oxidase * EC 1.4.3.4 Monoamine oxidase * EC 1.14.-.- Cytochrome P450 oxidase * EC 1.6.3.1 NADPH oxidase * EC 1.17.3.2 Xanthine oxidase * EC 1.1.3.8 L-gulonolactone oxidase * EC 1. ...
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Diplococci
Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archaea). Generally, the basic morphologies are spheres (coccus) and round-ended cylinders or rod shaped (bacillus). But, there are also other morphologies such as helically twisted cylinders (example '' Spirochetes''), cylinders curved in one plane (selenomonads) and unusual morphologies (the square, flat box-shaped cells of the Archaean genus '' Haloquadratum)''. Other arrangements include pairs, tetrads, clusters, chains and palisades. Types Coccus A coccus (plural ''cocci'', from the Latin ''coccinus'' (scarlet) and derived from the Greek ''kokkos'' (berry)), is any microorganism (usually bacteria) whose overall shape is spherical or nearly spherical. Coccus refers to the shape of the bacteria and can contain multiple genera, such as sta ...
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Victor Morax
Victor Morax (16 March 1866 – 14 May 1935) was an ophthalmologist born in Morges, Switzerland. He studied in Freiburg (Germany) and Paris, and from 1891 to 1903, he worked at the Pasteur Institute in Paris. From 1903 to 1928, he was associated with the Hôpital Lariboisière, rejoining the Pasteur Institute as a permanent member in 1929. In 1930, he became a member of the Académie de Médecine. While at the Pasteur Institute, Morax discovered the bacillus '' Moraxella lacunata'', a cause of chronic conjunctivitis. The disease is sometimes referred to as either "Morax' disease" or as "Axenfeld's conjunctivitis", named after German ophthalmologist Theodor Axenfeld (1867–1930), who made his discovery of the bacillus during the same time period as did Morax. In 1923, he became vice-president of the "International League Against Trachoma" with bacteriologist Charles Nicolle (1866–1936) serving as its president. In 1929, he published a treatise on the disorder titl ...
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Ophthalmology
Ophthalmology (, ) is the branch of medicine that deals with the diagnosis, treatment, and surgery of eye diseases and disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. In the United States, following graduation from medical school, one must complete a four-year residency in ophthalmology to become an ophthalmologist. Following residency, additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat ailments, such as eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care—medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many inc ...
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Moraxellaceae
The Moraxellaceae are a family of Gammaproteobacteria, including a few pathogenic species.George M. Garrity: ''Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Volume 2: ''The Proteobacteria, Part B: The Gammaproteobacteria'' Others are harmless commensals of mammals and humans or occur in water or soil. The species are mesophilic or psychrotrophic (''Psychrobacter'').R. Rossau, A. van Landschoot, M. Gillis & J. de Ley, "Taxonomy of Moraxellaceae ''fam. nov.'', a New Bacterial Family To Accommodate the Genera Moraxella, Acinetobacter, and ...
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