Moraxella Atlantae
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Moraxella Atlantae
''Moraxella atlantae'' is a Gram-negative, oxidase-positive and catalase-positive, rod-shaped, nonmotile bacterium in the genus ''Moraxella''. First described in 1976 it was recognized as a rare opportunistic pathogen in humans starting in 1991. Taxonomy and microbiological characteristics ''Moraxella atlantae'' was first described as a new species in 1976 based on biochemical and microbiological culture , microbiological growth characteristics:Bøvre, K., et al. "Moraxella atlantae sp. nov. and its distinction from Moraxella phenylpyrouvica." International Journal of Systematic and Evolutionary Microbiology 26.4 (1976): 511-521. It resembled ''Moraxella phenylpyruvica'', but differed in "simultaneous lack of urease and phenylalanine and tryptophan deaminase activities, inability to grow on solid medium at 4 to 10°C, relative salt sensitivity, and different behaviour on bile-containing media." In difference it also contains n-octadecanol and mannose. It is a non-fermenter and ha ...
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Gram-negative
Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists of a thin peptidoglycan cell wall sandwiched between an inner ( cytoplasmic) membrane and an outer membrane. These bacteria are found in all environments that support life on Earth. Within this category, notable species include the model organism '' Escherichia coli'', along with various pathogenic bacteria, such as '' Pseudomonas aeruginosa'', '' Chlamydia trachomatis'', and '' Yersinia pestis''. They pose significant challenges in the medical field due to their outer membrane, which acts as a protective barrier against numerous antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and the antimicrobial enzyme lysozyme produced by animals as part of their innate immune system. Furthe ...
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Mannose
Mannose is a sugar with the formula , which sometimes is abbreviated Man. It is one of the monomers of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several congenital disorders of glycosylation are associated with mutations in enzymes involved in mannose metabolism. Mannose is not an essential nutrient; it can be produced in the human body from glucose, or converted into glucose. Mannose provides 2–5  kcal/g. It is partially excreted in the urine. Etymology The root of both "mannose" and " mannitol" is manna, which the Bible describes as the food supplied to the Israelites during their journey in the region of Sinai. Several trees and shrubs can produce a substance called manna, such as the "manna tree" (''Fraxinus ornus'') from whose secretions mannitol was originally isolated. Structure Mannose commonly exists as two different-sized rings, the py ...
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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, treatment and antibiotic prophylaxis, prevention of such infections. They may either bactericide, kill or bacteriostatic agent, inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the ones which cause the common cold or influenza. Drugs which inhibit growth of viruses are termed antiviral drugs or antivirals. Antibiotics are also not effective against fungi. Drugs which inhibit growth of fungi are called antifungal drugs. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek language, Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against ...
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Dog Bite
A dog bite is a bite upon a person or other animal by a dog. More than one successive bite is often called a dog attack, although dog attacks can include knock-downs and scratches. Though some dog bites do not result in injury, they can result in infection, disfigurement, temporary or permanent disability, or Fatal dog attacks, death. Another type of dog bite is the "soft bite" displayed by well-trained dogs, by puppies, and in non-aggressive play. Dog bites can occur during dog fighting, as a response to animal abuse, mistreatment, by trained dogs working as guard dog, guard, police dog, police or Military dog, military animals, or during a random encounter. There is debate on whether or not certain dog breed, breeds of dogs are inherently more prone to commit attacks causing serious injury (i.e., so driven by instinct and breeding that, under certain circumstances, they are exceedingly likely to attempt or commit dangerous attacks). It is recognized that the risk of dog bite ...
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Pleural Fluid
The pleural cavity, or pleural space (or sometimes intrapleural space), is the potential space between the pleurae of the pleural sac that surrounds each lung. A small amount of serous pleural fluid is maintained in the pleural cavity to enable lubrication between the membranes, and also to create a pressure gradient. The serous membrane that covers the surface of the lung is the visceral pleura and is separated from the outer membrane, the parietal pleura, by just the film of pleural fluid in the pleural cavity. The visceral pleura follows the fissures of the lung and the root of the lung structures. The parietal pleura is attached to the mediastinum, the upper surface of the diaphragm, and to the inside of the ribcage. Structure In humans, the left and right lungs are completely separated by the mediastinum, and there is no communication between their pleural cavities. Therefore, in cases of a unilateral pneumothorax, the contralateral lung will remain functioning normal ...
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University Of Gothenburg
The University of Gothenburg () is a List of universities in Sweden, university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current List of universities in Sweden#Public universities, Swedish universities and, with 53,624 students and 6,707 staff members, it is one of the largest universities in the Nordic countries. About With its eight faculties and 38 departments, the University of Gothenburg is one of the most wide-ranging and versatile universities in Sweden. Its eight faculties offer training in the Creative Arts, Social Sciences, Natural Sciences, Humanities, Education, Information Technology, Business, Economics and Law, and Health Sciences. The University of Gothenburg has the highest number of applicants per study place in many of its subjects and courses, making it one of the most popular universities in Sweden. History The University of Gothenburg was founded as ''Göteborgs högskola'' (Gothenburg Uni ...
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Aortic Valve
The aortic valve is a valve in the heart of humans and most other animals, located between the left ventricle and the aorta. It is one of the four valves of the heart and one of the two semilunar valves, the other being the pulmonary valve. The aortic valve normally has three cusps or leaflets, although in 1–2% of the population it is found to congenitally have two leaflets. The aortic valve is the last structure in the heart the blood travels through before stopping the flow through the systemic circulation. Structure The aortic valve normally has three cusps however there is some discrepancy in their naming. They may be called the left coronary, right coronary and non-coronary cusp. Some sources also advocate they be named as a left, right and posterior cusp. Anatomists have traditionally named them the left posterior (origin of left coronary), anterior (origin of the right coronary) and right posterior. The three cusps, when the valve is closed, contain a sinus called ...
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Keratitis
Keratitis is a condition in which the human eye, eye's cornea, the clear dome on the front surface of the eye, becomes inflammation, inflamed. The condition is often marked by moderate to intense pain and usually involves any of the following symptoms: pain, impaired eyesight, photophobia (light sensitivity), Red eye (medicine), red eye and a 'gritty' sensation. Diagnosis of infectious keratitis is usually made clinically based on the signs and symptoms as well as eye examination, but corneal scrapings may be obtained and evaluated using microbiological culture or other testing to identify the causative pathogen. Classification (by chronicity) Acute * Acute epithelial keratitis * Nummular keratitis * Interstitial keratitis * Disciform keratitis Chronic * Neurotrophic keratitis * Mucous plaque keratitis Classification (infective) Viral The most common causes of viral keratitis include herpes simplex virus (HSV) and varicella zoster virus (VZV), which cause herpes of the eye ...
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16S RRNA
16S ribosomal RNA (or 16Svedberg, S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it are referred to as 16S rRNA genes and are used in reconstructing phylogenetics, phylogenies, due to the slow rates of evolution of this region of the gene. Carl Woese and George E. Fox were two of the people who pioneered the use of 16S rRNA in phylogenetics in 1977. Multiple sequences of the 16S rRNA gene can exist within a single bacterium. Terminology The descriptor ''16S'' refers to the size of these ribosomal subunits as reflected indirectly by the speed at which they sediment when samples are centrifuged. Thus ''16S'' means 16 Svedberg, Svedburg units. Functions * Like the 23S ribosomal RNA, large (23S) ribosomal RNA, it has a structural role, acting as a scaffold defining the positions of the ribosomal proteins. * The Directionality (molecular biolo ...
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Analytical Profile Index
The analytical profile index, or API, is a classification system for bacteria based on biochemical tests. The system was developed to accelerate the speed of identifying clinically relevant bacteria. It can only be used to identify known species from an index. The data obtained are phenotypic traits. DNA sequence-based methods, including multi-locus sequence typing and even whole-genome sequencing, are increasingly used in the identification of bacterial species and strains. These newer methods can be used to complement or even replace the use of API testing in clinical settings. History The analytical profile index (API) was invented in the 1970s in the United States by Pierre Janin of Analytab Products Inc. The API test system is currently manufactured by bioMérieux. The API range introduced a standardized and miniaturized version of existing techniques, which were considered complicated to perform and difficult to read. Description Identification is only possible with a ...
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Non-fermenter
Non-fermenters (also non-fermenting bacteria) are a taxonomically heterogeneous group of bacteria of the phylum Pseudomonadota that cannot catabolize glucose, and are thus unable to ferment. This does not necessarily exclude that species can catabolize other sugars or have anaerobiosis like fermenting bacteria. The coccoid or bacillary bacteria can be found in soil or wet areas. They are non- sporulating bacteria and Gram-negative. Some species are also pathogenic for humans, so their detection (e.g. with analytical profile index 20 NE) has great relevance in the diagnosis of bacterial infections. __TOC__ List of non-fermenters * '' Acinetobacter'' * '' Alcaligenes'' * '' Burkholderia'' * ''Moraxella'' * ''Pseudomonas'' * '' Shewanella'' * '' Stenotrophomonas'' Also, pathogenic species include ''Pseudomonas aeruginosa ''Pseudomonas aeruginosa'' is a common Bacterial capsule, encapsulated, Gram-negative bacteria, Gram-negative, Aerobic organism, aerobic–facultative ana ...
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Deaminase
Deamination is the removal of an amino group from a molecule. Enzymes that catalyse this reaction are called deaminases. In the human body, deamination takes place primarily in the liver; however, it can also occur in the kidney. In situations of excess protein intake, deamination is used to break down amino acids for energy. The amino group is removed from the amino acid and converted to ammonia. The rest of the amino acid is made up of mostly carbon and hydrogen, and is recycled or oxidized for energy. Ammonia is toxic to the human system, and enzymes convert it to urea or uric acid by addition of carbon dioxide molecules (which is not considered a deamination process) in the urea cycle, which also takes place in the liver. Urea and uric acid can safely diffuse into the blood and then be excreted in urine. Deamination reactions in DNA Cytosine Spontaneous deamination is the hydrolysis reaction of cytosine into uracil, releasing ammonia in the process. This can occur in vitro ...
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