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Iso-THC
Isotetrahydrocannabinol (iso-THC or Δ8-Isotetrahydrocannabinol) is a phytocannabinoid commonly found as a component in synthetic THC which has been made from acid-catalyzed cyclization of cannabidiol. iso-THC can be described as the upper cyclization product of CBD, while THC is the lower cyclization product of CBD. Its pharmacology has not been studied, though it is commonly found in commercially marketed Δ8-THC products. Via a migration of the exocyclic double bond iso-THC can easily rearrange to delta-4(8)-iso-THC, which can also be found in Δ8 THC products. Iso-THC can be found as an impurity in pharmaceutical Dronabinol. See also * Abeo-HHC acetate * Cannabicyclol * Cannabielsoin * Cis-THC ''cis''-Delta-9-Tetrahydrocannabinol ((-)-''cis''-Δ9-THC) is an isomer of tetrahydrocannabinol found in the ''Cannabis'' plant but in lower quantities than the more well-known ''trans'' isomer. Formation of cis-THC could take place in process o ... * Exo-THC References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cannabielsoin
Cannabielsoin (CBE) is a metabolite of cannabidiol, one of the major chemical components of cannabis. History Cannabielsoin in scientific journals was first cited in 1973. It was concluded that cannabielsoin was formed from cannabidiol as part of the metabolic process and is non-psychoactive. See also * Cannabicitran * Cannabicyclol * Cannabimovone * Cannabitriol * Iso-THC Isotetrahydrocannabinol (iso-THC or Δ8-Isotetrahydrocannabinol) is a phytocannabinoid commonly found as a component in synthetic THC which has been made from acid-catalyzed cyclization of cannabidiol. iso-THC can be described as the upper cyc ... References Cannabis Dibenzofurans Isopropenyl compounds Hydroxyarenes Tertiary alcohols Human drug metabolites Phytocannabinoids {{Cannabis-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abeo-HHC Acetate
Abeo-HHC acetate is a semi-synthetic derivative of tetrahydrocannabinol, first described in the 1980s. It is synthesised from delta-11-tetrahydrocannabinol, which can be made to undergo a ring expansion reaction via a hydrazone intermediate. It is structurally similar to HHC-acetate except that the methylated cyclohexyl ring has been replaced by a cycloheptane. See also * Cis-THC * Cycloheptyl CP 55,940 * Hexahydrocannabinol * Iso-THC * O-1656 * THC-O-acetate THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term ''THC-O-acetate'' and its variations are commonly used for two types of the substance, dependent on which cannabinoid it is synthesized from. ... References Cannabinoids Oxygen heterocycles Heterocyclic compounds with 3 rings Acetate esters {{cannabinoid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cis-THC
''cis''-Delta-9-Tetrahydrocannabinol ((-)-''cis''-Δ9-THC) is an isomer of tetrahydrocannabinol found in the ''Cannabis'' plant but in lower quantities than the more well-known ''trans'' isomer. Formation of cis-THC could take place in process of epimerization associated with acid-catalyzed cyclization of CBD to THC. It has similar psychoactive effects to ''trans''-Δ9-THC in tests on mice, but with only around 1/5th the potency. The equivalent Δ8 isomer is also known as a synthetic compound, but has not been isolated from ''Cannabis'' plant material. All four cis/trans isomers are known, though only the (6aR,10aR) and (6aS,10aR) enantiomers are psychoactive, while the others retain activity at targets such as GPR18 and GPR55. See also * Abeo-HHC acetate * Abn-CBD * CBD-DMH * Exo-THC * Iso-THC * HU-211 * Perrottetinene Perrottetinene is a naturally occurring cannabinoid compound found in liverworts from the family Radulaceae native to Japan, New Zealand and Costa Ri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytocannabinoid
Cannabinoids () are several structural classes of compounds found primarily in the ''Cannabis'' plant or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoactive compound in cannabis. Cannabidiol (CBD) is also a major constituent of temperate cannabis plants and a minor constituent in tropical varieties. At least 100 distinct phytocannabinoids have been isolated from cannabis, although only four (i.e., THCA, CBDA, CBCA and their common precursor CBGA) have been demonstrated to have a biogenetic origin. It was reported in 2020 that phytocannabinoids can be found in other plants such as rhododendron, licorice and liverwort, and earlier in Echinacea. Phytocannabinoids are multi-ring phenolic compounds structurally related to THC, but endocannabinoids are fatty acid derivatives. Nonclassical synthetic cannabinoids (cannabimimetics) include aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cannabidiol
Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in ''Cannabis'', along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. Medically, it is an anticonvulsant used to treat multiple forms of epilepsy. It was discovered in 1940 and, as of 2024 clinical research on CBD included studies related to the treatment of anxiety, addiction, psychosis, movement disorders, and pain, but there is insufficient evidence-based medicine, high-quality evidence that CBD is effective for these conditions. CBD is sold as an herbal dietary supplement and promoted with yet unproven claims of particular therapeutic effects. Cannabidiol can be route of administration, taken internally in multiple ways, including by Route of administration#Inhalation, inhaling cannabis cannabis smoking, smoke or vaporizer (inhalation device), vapor, Oral administration, swallowing it by mouth, and through use of an aerosol spray into the buccal administration, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dronabinol
Dronabinol (), sold under the brand names Marinol and Syndros, is the generic name for the molecule of (−)-trans-Δ9-tetrahydrocannabinol (THC) in the pharmaceutical context. It has indications as an appetite stimulant, antiemetic, and sleep apnea reliever and is approved by the US Food and Drug Administration (FDA) as safe and effective for HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting. Dronabinol is the principal psychoactive constituent enantiomer form, (−)-''trans''-Δ9-tetrahydrocannabinol, found in ''Cannabis sativa'' L. plants, but can also be synthesized in laboratory. Dronabinol does not include any other tetrahydrocannabinol (THC) isomers or any cannabidiol (CBD). Medical uses Low appetite and nausea Dronabinol is used to stimulate appetite and therefore weight gain in patients with HIV/AIDS and cancer. It is also used to treat chemotherapy-induced nausea and vomiting. Pain Dronabinol demonstrated analgesic efficacy in a majority o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cannabicyclol
Cannabicyclol (CBL) is a non-psychoactive cannabinoid found in ''Cannabis''. CBL is a degradative product like cannabinol, with cannabichromene degrading into CBL through natural irradiation or under acid conditions. CBL is not scheduled under the Convention on Psychotropic Substances. See also * Cannabis * Medical cannabis References External links CTD's Cannabicyclol pagefrom the Comparative Toxicogenomics Database The Comparative Toxicogenomics Database (CTD) is a public website and research tool launched in November 2004 that curates scientific data describing relationships between chemicals/drugs, genes/proteins, diseases, taxa, phenotypes, GO annotations, ... Wiley-VCH list of chemicals Phytocannabinoids Hydroxyarenes Benzopyrans Cyclobutanes Cyclopentanes Heterocyclic compounds with 4 rings {{cannabinoid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytocannabinoids
Cannabinoids () are several structural classes of compounds found primarily in the ''Cannabis'' plant or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoactive compound in cannabis. Cannabidiol (CBD) is also a major constituent of temperate cannabis plants and a minor constituent in tropical varieties. At least 100 distinct phytocannabinoids have been isolated from cannabis, although only four (i.e., THCA, CBDA, CBCA and their common precursor CBGA) have been demonstrated to have a biogenetic origin. It was reported in 2020 that phytocannabinoids can be found in other plants such as rhododendron, licorice and liverwort, and earlier in Echinacea. Phytocannabinoids are multi-ring phenolic compounds structurally related to THC, but endocannabinoids are fatty acid derivatives. Nonclassical synthetic cannabinoids (cannabimimetics) include aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygen Heterocycles
Oxygen is a chemical element; it has symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and a potent oxidizing agent that readily forms oxides with most elements as well as with other compounds. Oxygen is the most abundant element in Earth's crust, making up almost half of the Earth's crust in the form of various oxides such as water, carbon dioxide, iron oxides and silicates.Atkins, P.; Jones, L.; Laverman, L. (2016).''Chemical Principles'', 7th edition. Freeman. It is the third-most abundant element in the universe after hydrogen and helium. At standard temperature and pressure, two oxygen atoms will bind covalently to form dioxygen, a colorless and odorless diatomic gas with the chemical formula . Dioxygen gas currently constitutes approximately 20.95% molar fraction of the Earth's atmosphere, though this has changed considerably over long periods of time in Earth's history. A much rarer triat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
