Iso-THC
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Isotetrahydrocannabinol (iso-THC or Δ8-Isotetrahydrocannabinol) is a
phytocannabinoid Cannabinoids () are several structural classes of compounds found primarily in the ''Cannabis'' plant or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoac ...
commonly found as a component in synthetic THC which has been made from acid-catalyzed cyclization of
cannabidiol Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in ''Cannabis'', along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. Medically, it is an anticonvulsant used to treat multiple f ...
. iso-THC can be described as the upper cyclization product of CBD, while THC is the lower cyclization product of CBD. Its pharmacology has not been studied, though it is commonly found in commercially marketed Δ8-THC products. Via a migration of the exocyclic double bond iso-THC can easily rearrange to delta-4(8)-iso-THC, which can also be found in Δ8 THC products. Iso-THC can be found as an impurity in pharmaceutical
Dronabinol Dronabinol (), sold under the brand names Marinol and Syndros, is the generic name for the molecule of (−)-trans-Δ9-tetrahydrocannabinol (THC) in the pharmaceutical context. It has indications as an appetite stimulant, antiemetic, and sleep ...
.


See also

*
Abeo-HHC acetate Abeo-HHC acetate is a semi-synthetic derivative of tetrahydrocannabinol, first described in the 1980s. It is synthesised from delta-11-tetrahydrocannabinol, which can be made to undergo a ring expansion reaction via a hydrazone intermediate. It ...
*
Cannabicyclol Cannabicyclol (CBL) is a non-psychoactive cannabinoid found in ''Cannabis''. CBL is a degradative product like cannabinol, with cannabichromene degrading into CBL through natural irradiation or under acid conditions. CBL is not scheduled under ...
* Cannabielsoin *
Cis-THC ''cis''-Delta-9-Tetrahydrocannabinol ((-)-''cis''-Δ9-THC) is an isomer of tetrahydrocannabinol found in the ''Cannabis'' plant but in lower quantities than the more well-known ''trans'' isomer. Formation of cis-THC could take place in process o ...
* Exo-THC


References

Benzochromenes Phytocannabinoids Oxygen heterocycles Heterocyclic compounds with 3 rings Isopropenyl compounds {{cannabinoid-stub