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Institute Of Molecular Biotechnology
The Institute of Molecular Biotechnology (IMBA) is an independent biomedical research organisation founded by the Austrian Academy of Sciences in cooperation with the pharmaceutical company Boehringer Ingelheim. The institute employs around 250 people from over 40 countries, who perform basic research. IMBA is located at the Vienna Biocenter, Vienna BioCenter (VBC) and shares facilities and scientific training programs with the Gregor Mendel Institute, Gregor Mendel Institute of Molecular Plant Biology (GMI) of the Austrian Academy of Sciences and the Research Institute of Molecular Pathology (IMP), the basic research center of Boehringer Ingelheim. Research The research at IMBA aims to understand the fundamental molecular biology, molecular biological processes underlying the 3D architecture of genomes, the functions of small RNAs, and the ''in vitro'' reconstitution from stem cells of whole organs and embryos. The institute comprises 14 research groups (as of July 2024): * Ste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Austrian Academy Of Sciences
The Austrian Academy of Sciences (; ÖAW) is a legal entity under the special protection of the Republic of Austria. According to the statutes of the Academy its mission is to promote the sciences and humanities in every respect and in every field, particularly in fundamental research. History In 1713, Gottfried Wilhelm Leibniz suggested to establish an Academy, inspired by the Royal Society and the French Academy of Sciences. The "Kaiserliche Akademie der Wissenschaften in Wien" was finally established by Imperial Patent on 14 May 1847. The academy soon began extensive research. In the humanities the academy started with researching and publishing important historical sources of Austria. Research in natural science also covered a wide variety of topics. The 1921 federal law guaranteed the legal basis of the academy in the newly founded First Austrian Republic. From the mid-1960s onwards it became the country's leading institution in the field of non-university basic research. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histone Acetylation And Deacetylation
Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminus, N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation. Histone acetylation and deacetylation are essential parts of Regulation of gene expression, gene regulation. These reactions are typically catalysed by enzymes with "histone acetyltransferase" (HAT) or "histone deacetylase" (HDAC) activity. Acetylation is the process where an acetyl functional group is transferred from one molecule (in this case, acetyl coenzyme A) to another. Deacetylation is simply the reverse reaction where an acetyl group is removed from a molecule. Acetylated histones, octameric proteins that organize chromatin into nucleosomes, the basic structural unit of the chromosomes and ultimately higher order structures, represent a type of epigenetic marker within chromatin. Acetylation removes the positive charge on the histones, thereb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maria Leptin
Maria Leptin (born 15 September 1954) is a German developmental biologist and immunologist, and the current president of the European Research Council. She was the director of the European Molecular Biology Organization from 2010 to 2021. Education Leptin studied mathematics and biology at the University of Bonn and the Heidelberg University. Initially planning to become a teacher, she decided to pursue a PhD in 1979 at the Basel Institute for Immunology after a practical taught by researchers from the institute. She was supervised by Fritz Melchers and studied B-cell activation and maturation into plasma cells as part of the immune response to infections. She completed her PhD in 1983. Career After her PhD, in 1984, Leptin joined Michael Wilcox's group at the MRC Laboratory of Molecular Biology (LMB) in Cambridge as a postdoctoral fellow. It is here that she became involved in developmental biology, studying the role of position-specific integrins in the embryonic devel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paris Descartes University
Paris Descartes University (), also known as Paris V, was a French public university located in Paris. It was one of the inheritors of the historic University of Paris, which was split into 13 universities in 1970. Paris Descartes completely merged with Paris Diderot University in 2019 to form a new Paris Cité University. It was established as a multidisciplinary university "of humanities and health sciences" ("''des Sciences de l’Homme et de la Santé''". It focused on the areas of medical sciences, biomedical sciences, law, computer science, social sciences, economics and psychology. Its main campus was in the historic École de Chirurgie in the 6th arrondissement of Paris. History The historic University of Paris () first appeared in the second half of the 12th century, but was divided into thirteen universities, managed by a common rectorate, the Chancellerie des Universités de Paris, after the student protests of the French May. Administration Campus Descartes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guido Kroemer
Guido Kroemer (born 11 June 1961) is a cell biologist who has made contributions to the understanding of the role of mitochondria in cell death. He is a member of multiple scientific academies in Europe and is one of the most highly cited authors in cell biology. Biography Kroemer was born in Leer, Germany. He completed medical school at the University of Innsbruck in Austria and earned a Ph.D. in biology from the Autonomous University of Madrid. Early in his career, Kroemer worked for the Spanish National Research Council. Now based in France, he is a cell biology researcher with INSERM and a Professor of the Faculty of Medicine of Paris Descartes University. Kroemer first discovered the fact that mitochondrial membrane permeabilization is a concrete step in the process of programmed cell death. In a publication analysis by the news magazine ''Lab Times'', Kroemer was the most highly cited cell biologist for the period between 2007 and 2013. Three other scientists who had worke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, botany, genomics, and quantitative biology. It is located in Laurel Hollow, New York, in Nassau County, on Long Island. It is one of 68 institutions supported by the Cancer Centers Program of the U.S. National Cancer Institute (NCI) and has been an NCI-designated Cancer Center since 1987. The Laboratory is one of a handful of institutions that played a central role in the development of molecular genetics and molecular biology. It has been home to eight scientists who have been awarded the Nobel Prize in Physiology or Medicine. CSHL is ranked among the leading basic research institutions in molecular biology and genetics, with Thomson Reuters ranking it first in the world. CSHL was also ranked first in research output worldwide by ''Nature''. The Laboratory is led by Bruce Stillman, a biochemist and cancer researcher. Since its incepti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cambridge
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, world's third-oldest university in continuous operation. The university's founding followed the arrival of scholars who left the University of Oxford for Cambridge after a dispute with local townspeople. The two ancient university, ancient English universities, although sometimes described as rivals, share many common features and are often jointly referred to as Oxbridge. In 1231, 22 years after its founding, the university was recognised with a royal charter, granted by Henry III of England, King Henry III. The University of Cambridge includes colleges of the University of Cambridge, 31 semi-autonomous constituent colleges and List of institutions of the University of Cambridge#Schools, Faculties, and Departments, over 150 academic departm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gregory Hannon
Gregory James Hannon One or more of the preceding sentences incorporates text from the royalsociety.org website where: (born 1964) is a professor of molecular cancer biology and director of the Cancer Research UK Cambridge Institute at the University of Cambridge. He is a Fellow of Trinity College, Cambridge while also serving as a director of cancer genomics at the New York Genome Center and an adjunct professor at Cold Spring Harbor Laboratory. Career and research Hannon is known for his contributions to small RNA biology, cancer biology, and mammalian genomics. He has a history in discovery of oncogenes, beginning with work that led to the identification of CDK inhibitors and their links to cancer. More recently, his work has focused on small RNA biology, which led to an understanding of the biochemical mechanisms and biological functions of RNA interference (RNAi). He has developed widely used tools and strategies for manipulation of gene expression in mammalian cells ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is Carnegie Classification of Institutions of Higher Education, classified as a "Special Focus – Research Institution". Rockefeller is the oldest biomedical research institute in the United States. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue / Sutton Place, York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'', the ''Journal of Cell Biology'', and ''The Journal of General Physiology''. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Scienc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elaine Fuchs
Elaine V. Fuchs is an American cell biologist known for her work on the biology and molecular mechanisms of mammalian skin and skin diseases, who helped lead the modernization of dermatology. Fuchs pioneered reverse genetics approaches, which assess protein function first and then assess its role in development and disease. In particular, Fuchs researches skin stem cells and their production of hair and skin. She is an investigator at the Howard Hughes Medical Institute and the Rebecca C. Lancefield Professor of Mammalian Cell Biology and Development at The Rockefeller University. Early life and education Fuchs grew up outside Chicago, in a family of scientists—her father, aunt, and sister were also scientists, and her family encouraged her to pursue higher education.Fiona Watt. "Women in Cell Science: Elaine Fuchs", Journal of Cell Science, v. 117, n. 4877-4879 (2004). She said those influences were especially important to her as a child. During an interview with Faiza E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Janelia Research Campus
Janelia Research Campus is a scientific research campus of the Howard Hughes Medical Institute that opened in October 2006. The campus is located in Loudoun County, Virginia, near the town of Ashburn. It is known for its scientific research and modern architecture. The current executive director of the laboratory is Nelson Spruston, who is also a vice-president of HHMI. He succeeded Ronald Vale in 2024, who in turn succeeded the initial director Gerald M. Rubin in 2020. The campus was known as "Janelia Farm Research Campus" until 2014. Research Most HHMI-funded research supports investigators working at their home institutions. However, some interdisciplinary problems are difficult to address in existing research settings, and Janelia was built as a separate institution to address such problems in neurobiology. As of February 2025, it had 650 employees. They specifically address the identification of general principles governing information processing by neuronal circuits, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barry Dickson
Barry J. Dickson (born 14 August 1962) is an Australian neurobiologist who studies the development of neuronal networks in the fruit fly Drosophila melanogaster. Dickson is a group leader at the Janelia Research Campus of the Howard Hughes Medical Institute in Loudoun County, Virginia and a former scientific director of the Research Institute of Molecular Pathology (IMP) in Vienna, Austria. Early life and education Barry Dickson was born in Melbourne, and studied mathematics, computer science and genetics at the University of Melbourne. He received his first bachelor of science degree in 1984. Until 1986, Dickson worked as a research assistant at the epidemiology unit at the University of Melbourne and at the Menzies School of Health Research in Darwin. He received a second bachelor of science with honors in 1987 for his thesis about “Interactions between multiple operator sites controlling transcription of the aroFtyrA operon of Escherichia coli K-12”. Dickson gained furt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
