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Grace Bio-Labs
Grace Bio-Labs is a global supplier of pharmaceutical, biomedical, and biochemical research products based in Bend, Oregon, United States. They develop the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide)Cytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.High Definition cell analysis in situ using microporous films. Cell Vision, vol. 2, No 6: 499-590, 1995. and the modern hybridization and incubation chambers for glass microscope slides.McGrath, Charles M.; Grudzien, Jennipher L.; Levine, Allan. Influence of Surface: Volume ratio of Reaction Chambers on Stoichiometry of Antibody-Based Reactions in Situ. Cell Vision, Vol 2, No. 2. 165-169, 1995. History Originally based near Detroit, Michigan, and founded by Charles McGrath in 1986, Grace Bio Labs relocated to Bend, Oregon in May, 1990. With the aid of SBIR funding, Grace Bio-Labs was built on two main product types ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Microarray
A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function, and determining function on a large scale. Its main advantage lies in the fact that large numbers of proteins can be tracked in parallel. The chip consists of a support surface such as a glass slide, nitrocellulose membrane, bead, or microtitre plate, to which an array of capture proteins is bound. Probe molecules, typically labeled with a fluorescent dye, are added to the array. Any reaction between the probe and the immobilised protein emits a fluorescent signal that is read by a laser scanner. Protein microarrays are rapid, automated, economical, and highly sensitive, consuming small quantities of samples and reagents. The concept and methodology of protein microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) in 1983 in a scientific publication and a series of pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Companies Established In 1986
A company, abbreviated as co., is a legal entity representing an association of people, whether natural, legal or a mixture of both, with a specific objective. Company members share a common purpose and unite to achieve specific, declared goals. Companies take various forms, such as: * voluntary associations, which may include nonprofit organizations * business entities, whose aim is generating profit * financial entities and banks * programs or educational institutions A company can be created as a legal person so that the company itself has limited liability as members perform or fail to discharge their duty according to the publicly declared incorporation, or published policy. When a company closes, it may need to be liquidated to avoid further legal obligations. Companies may associate and collectively register themselves as new companies; the resulting entities are often known as corporate groups. Meanings and definitions A company can be defined as an "artificial per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Companies Based In Oregon
This is a list of companies based in Oregon. Oregon is the ninth largest by area and the 27th most populous of the 50 United States. The gross domestic product (GDP) of Oregon in 2010 was $168.6 billion; it is the United States's 26th wealthiest state by GDP. The state's per capita personal income in 2010 was $44,447. Oregon has one of the largest salmon-fishing industries in the world, although ocean fisheries have reduced the river fisheries in recent years. The state is home to many breweries, and Portland has the largest number of breweries of any city in the world. High technology industries and services have been major employers since the 1970s. Tektronix was the largest private employer in Oregon until the late 1980s. Intel's creation and expansion of several facilities in eastern Washington County continued the growth that Tektronix had started. Intel is now the state's largest for-profit private employer, with more than 17,000 employees, while Providence Health & Serv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Southeast Asia
Southeast Asia, also spelled South East Asia and South-East Asia, and also known as Southeastern Asia, South-eastern Asia or SEA, is the geographical United Nations geoscheme for Asia#South-eastern Asia, south-eastern region of Asia, consisting of the regions that are situated south of mainland China, east of the Indian subcontinent, and north-west of mainland Australia. Southeast Asia is bordered to the north by East Asia, to the west by South Asia and the Bay of Bengal, to the east by Oceania and the Pacific Ocean, and to the south by Australia (continent), Australia and the Indian Ocean. Apart from the British Indian Ocean Territory and two out of atolls of Maldives, 26 atolls of Maldives in South Asia, Maritime Southeast Asia is the only other subregion of Asia that lies partly within the Southern Hemisphere. Mainland Southeast Asia is completely in the Northern Hemisphere. East Timor and the southern portion of Indonesia are the only parts that are south of the Equator. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
East Asia
East Asia is the eastern region of Asia, which is defined in both geographical and ethno-cultural terms. The modern states of East Asia include China, Japan, Mongolia, North Korea, South Korea, and Taiwan. China, North Korea, South Korea and Taiwan are all unrecognised by at least one other East Asian state due to severe ongoing political tensions in the region, specifically the division of Korea and the political status of Taiwan. Hong Kong and Macau, two small coastal quasi-dependent territories located in the south of China, are officially highly autonomous but are under Chinese sovereignty. Japan, Taiwan, South Korea, Mainland China, Hong Kong, and Macau are among the world's largest and most prosperous economies. East Asia borders Siberia and the Russian Far East to the north, Southeast Asia to the south, South Asia to the southwest, and Central Asia to the west. To the east is the Pacific Ocean and to the southeast is Micronesia (a Pacific Ocean island group, clas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Europe
Central Europe is an area of Europe between Western Europe and Eastern Europe, based on a common historical, social and cultural identity. The Thirty Years' War (1618–1648) between Catholicism and Protestantism significantly shaped the area's history. The concept of "Central Europe" appeared in the 19th century. Central Europe comprised most of the territories of the Holy Roman Empire and those of the two neighboring kingdoms of Poland and Hungary. Hungary and parts of Poland were later part of the Habsburg monarchy, which also significantly shaped the history of Central Europe. Unlike their Western European (Portugal, Spain et al.) and Eastern European (Russia) counterparts, the Central European nations never had any notable colonies (either overseas or adjacent) due to their inland location and other factors. It has often been argued that one of the contributing causes of both World War I and World War II was Germany's lack of original overseas colonies. After ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
North America
North America is a continent in the Northern Hemisphere and almost entirely within the Western Hemisphere. It is bordered to the north by the Arctic Ocean, to the east by the Atlantic Ocean, to the southeast by South America and the Caribbean Sea, and to the west and south by the Pacific Ocean. Because it is on the North American Plate, North American Tectonic Plate, Greenland is included as a part of North America geographically. North America covers an area of about , about 16.5% of Earth's land area and about 4.8% of its total surface. North America is the third-largest continent by area, following Asia and Africa, and the list of continents and continental subregions by population, fourth by population after Asia, Africa, and Europe. In 2013, its population was estimated at nearly 579 million people in List of sovereign states and dependent territories in North America, 23 independent states, or about 7.5% of the world's population. In Americas (terminology)#Human ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteomic
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bend, Oregon
Bend is a city in and the county seat of Deschutes County, Oregon, United States. It is the principal city of the Bend Metropolitan Statistical Area. Bend is Central Oregon's largest city, with a population of 99,178 at the time of the 2020 U.S. Census, up from 76,693 at the time of the 2010 U.S. Census, and 52,029 at the 2000 census. The Bend metro population was 198,253 as of the 2020 census. It is the fifth largest metropolitan area in Oregon. Bend is located on the eastern edge of the Cascade Range along the Deschutes River. There the Ponderosa pine forest transitions into the high desert, characterized by arid land, junipers, sagebrush, and bitterbrush. Originally a crossing point on the river, settlement began in the early 1900s. Bend was incorporated as a city in 1905. Economically, it started as a logging town but is now identified as a gateway for many outdoor sports, including mountain biking, fishing, hiking, camping, rock climbing, white-water rafting, sk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Lysate
Lysis ( ) is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic" ) mechanisms that compromise its integrity. A fluid containing the contents of lysed cells is called a ''lysate''. In molecular biology, biochemistry, and cell biology laboratories, cell cultures may be subjected to lysis in the process of purifying their components, as in protein purification, DNA extraction, RNA extraction, or in purifying organelles. Many species of bacteria are subject to lysis by the enzyme lysozyme, found in animal saliva, egg white, and other secretions. Phage lytic enzymes ( lysins) produced during bacteriophage infection are responsible for the ability of these viruses to lyse bacterial cells. Penicillin and related β-lactam antibiotics cause the death of bacteria through enzyme-mediated lysis that occurs after the drug causes the bacterium to form a defective cell wall. If the cell wall is completely lost and the penicillin was u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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