Grace Bio-Labs is a global supplier of
pharmaceutical
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...
, biomedical, and biochemical research products based in
Bend, Oregon
Bend is a city in central Oregon and the county seat of Deschutes County, Oregon, Deschutes County, Oregon, United States. It is located to the east of the Cascade Range, on the Deschutes River.
The site became known by pioneers as a ford (cros ...
, United States. They develop the thin-cast nitrocellulose
biochip
In molecular biology, biochips are engineered substrates ("miniaturized laboratories") that can host large numbers of simultaneous biochemical reactions. One of the goals of biochip technology is to efficiently screen large numbers of biological ...
(aka:
nitrocellulose slide, nitrocellulose film slide)
[Cytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.][High Definition cell analysis in situ using microporous films. Cell Vision, vol. 2, No 6: 499-590, 1995.] and the modern hybridization and incubation chambers for glass microscope slides.
[McGrath, Charles M.; Grudzien, Jennipher L.; Levine, Allan. Influence of Surface: Volume ratio of Reaction Chambers on Stoichiometry of Antibody-Based Reactions in Situ. Cell Vision, Vol 2, No. 2. 165-169, 1995.]
History
Originally based near
Detroit, Michigan
Detroit ( , ) is the List of municipalities in Michigan, most populous city in the U.S. state of Michigan. It is situated on the bank of the Detroit River across from Windsor, Ontario. It had a population of 639,111 at the 2020 United State ...
, and founded by Charles McGrath in 1986, Grace Bio Labs relocated to
Bend, Oregon
Bend is a city in central Oregon and the county seat of Deschutes County, Oregon, Deschutes County, Oregon, United States. It is located to the east of the Cascade Range, on the Deschutes River.
The site became known by pioneers as a ford (cros ...
in May, 1990.
With the aid of
SBIR funding, Grace Bio-Labs was built on two main product types. The first is the incubation chamber for
cell culture
Cell culture or tissue culture is the process by which cell (biology), cells are grown under controlled conditions, generally outside of their natural environment. After cells of interest have been Cell isolation, isolated from living tissue, ...
and analysis; the second is the ONCYTE Nitrocellulose Film Slide. Their incubation and hybridization chambers are fluid delivery and containment products that increase sensitivity and efficiency in fluorescence and color-based protein and cell analyte assays.
Janitz, M. The HybriWell Sealing System from Grace Bio-Labs. BioCompare, January 1, 03.
The ONCYTE Nitrocellulose microporous film (
nitrocellulose slide) is a biochip platform that captures and protects the 3-dimensional (tertiary) structure of biological material. Originally designed for tissue printing
and
cell lysate
Lysis ( ; from Greek language, Greek 'loosening') is the breaking down of the cell membrane, membrane of a Cell (biology), cell, often by virus, viral, enzyme, enzymic, or osmosis, osmotic (that is, "lytic" ) mechanisms that compromise its in ...
capture, the film has flourished in
proteomic
Proteomics is the large-scale study of proteins. Proteins are vital macromolecules of all living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replicatio ...
s. It is commonly used in automated and manual
protein microarray
A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function, and determining function on a large scale. Its main advantage lies in the fact that larg ...
s, and continues to increase throughput in proteomics research.
Assay: Protein Microarrays on Nitrocellulose Slides. Genetic Engineering and Biotechnology News, Vol. 26, No 2. Mary Ann Liebert, Inc. Publishers: Jan 15, 2006.
Customer Base
Grace Bio-Labs sells to university research laboratories, biotech companies, private researchers and pharmaceutical companies. They mainly distribute to
North America
North America is a continent in the Northern Hemisphere, Northern and Western Hemisphere, Western hemispheres. North America is bordered to the north by the Arctic Ocean, to the east by the Atlantic Ocean, to the southeast by South Ameri ...
, Western and
Central Europe
Central Europe is a geographical region of Europe between Eastern Europe, Eastern, Southern Europe, Southern, Western Europe, Western and Northern Europe, Northern Europe. Central Europe is known for its cultural diversity; however, countries in ...
,
East Asia
East Asia is a geocultural region of Asia. It includes China, Japan, Mongolia, North Korea, South Korea, and Taiwan, plus two special administrative regions of China, Hong Kong and Macau. The economies of Economy of China, China, Economy of Ja ...
, and
Southeast Asia
Southeast Asia is the geographical United Nations geoscheme for Asia#South-eastern Asia, southeastern region of Asia, consisting of the regions that are situated south of China, east of the Indian subcontinent, and northwest of the Mainland Au ...
.
See also
*
List of companies based in Oregon
This is a list of companies based in Oregon. Oregon is the List of U.S. states and territories by area, ninth largest by area and the List of U.S. states and territories by population, 27th most populous of the List of U.S. states, 50 United Stat ...
References
External links
*
{{Authority control
Companies based in Bend, Oregon
Companies established in 1986
1986 establishments in Oregon
Research support companies