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George D. Snell
George Davis Snell NAS (December 19, 1903 – June 6, 1996) was an American mouse geneticist and basic transplant immunologist. Work George Snell shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and Jean Dausset for their discoveries concerning "genetically determined structures on the cell surface that regulate immunological reactions". Snell specifically "discovered the genetic factors that determine the possibilities of transplanting tissue from one individual to another. It was Snell who introduced the concept of H antigensSnell's work in mice led to the discovery of Human leukocyte antigen, HLA, the major histocompatibility complex, in humans (and all vertebrates) that is analogous to the H-2 complex in mice. Recognition of these key genes was prerequisite to successful tissue and organ transplantation. Life George Snell was born in Bradford, Massachusetts, the youngest of three children. His father (who was born in Minnesota) worked as a sec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bradford, Massachusetts
Bradford is a village and former town in Essex County, Massachusetts, United States. Eastern Bradford is the current town of Groveland, while western Bradford was annexed by the city of Haverhill, and today consists of the part of Haverhill on the south bank of the Merrimack River. While its separate existence from Haverhill has been largely obscured, the names of many locations in the area still bear the Bradford name. Bradford never forgets. History Bradford was originally part of the town of Rowley, and was called "Rowley on the Merrimack", "Rowley Village by the Merrimack", "Merrimac Lands", or just "Merrimack" before the name was changed to Bradford at a town meeting held January 7, 1672. It was named in memory of Bradford in the West Riding of Yorkshire, England, from which some of the settlers had emigrated, and first paid colonial tax on October 13, 1675. The east parish of Bradford (established in 1726) separated in 1850 and was incorporated as the town of Grovel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean Dausset
Jean-Baptiste-Gabriel-Joachim Dausset (19 October 1916 – 6 June 2009) was a French immunologist born in Toulouse, France. Dausset received the Nobel Prize in Physiology or Medicine in 1980 along with Baruj Benacerraf and George Davis Snell for their discovery and characterisation of the genes making the major histocompatibility complex. Using the money from his Nobel Prize and a grant from the French Television, Dausset founded the Human Polymorphism Study Center ( CEPH) in 1984, which was later renamed the Foundation Jean Dausset-CEPH in his honour. He married Rose Mayoral in 1963, with whom he had two children, Henri and Irène. Jean Dausset died on June 6, 2009, in Majorca, Spain, at the age of 92. Early life Jean-Baptiste-Gabriel-Joachim Dausset was born on 19 October 1916, in Toulouse, France. He was the youngest of four children of Henri Dausset and Elisabeth Dausset (born Renard). His father was from the Pyrénées, and was a doctor by profession, and his mother was a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred Nobel, Alfred Nobel's death. The original Nobel Prizes covered five fields: Nobel Prize in Physics, physics, Nobel Prize in Chemistry, chemistry, Nobel Prize in Physiology or Medicine, physiology or medicine, Nobel Prize in Literature, literature, and Nobel Peace Prize, peace, specified in Nobel's will. A sixth prize, the Nobel Memorial Prize in Economic Sciences, Prize in Economic Sciences, was established in 1968 by Sveriges Riksbank (Sweden's central bank) in memory of Alfred Nobel. The Nobel Prizes are widely regarded as the most prestigious awards available in their respective fields.Nobel Prize#Shalev69, Shalev, p. 8. Except in extraordinary circumstances, such as war, all six prizes are given annually. Each recipient, known as a laur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Texas
The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas, United States. Founded in 1883, it is the flagship institution of the University of Texas System. With 53,082 students as of fall 2023, it is also the largest institution in the system. The university is a major center for academic research, with research expenditures totaling $1.06 billion for the 2023 fiscal year. It joined the Association of American Universities in 1929. The university houses seven museums and seventeen libraries, including the Lyndon B. Johnson Presidential Library and the Blanton Museum of Art, and operates various auxiliary research facilities, such as the J. J. Pickle Research Campus and McDonald Observatory. UT Austin's athletics constitute the Texas Longhorns. The Longhorns have won four NCAA Division I National Football Championships, six NCAA Division I National Baseball Championships, sixteen NCAA Division I National Men's Swimming ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of colonial-era Massachusetts Bay Colony. While never formally affiliated with any denomination, Harvard trained Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston elite. Following the American Civil War, under Harvard president Charles William Eliot's long tenure from 1869 to 1909, Harvard developed multiple professional schools, which transfo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Linkage
Genetic linkage is the tendency of Nucleic acid sequence, DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two Genetic marker, genetic markers that are physically near to each other are unlikely to be separated onto different Chromatid, chromatids during chromosomal crossover, and are therefore said to be more ''linked'' than markers that are far apart. In other words, the nearer two Gene, genes are on a chromosome, the lower the chance of Genetic recombination, recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly ''unlinked'', although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located. Genetic linkage is the most prominent exception to Gregor M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mendelian Inheritance
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. These principles were initially controversial. When Mendel's theories were integrated with the Boveri–Sutton chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics. Ronald Fisher combined these ideas with the theory of natural selection in his 1930 book '' The Genetical Theory of Natural Selection'', putting evolution onto a mathematical footing and forming the basis for population genetics within the modern evolutionary synthesis. History The principles of Mendelian inheritance were named for and first derived by Gregor Johann Mendel, a nineteenth-century Moravian monk who formulated his ideas after conducting simple hybridization experiments with pea p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor's Degree
A bachelor's degree (from Medieval Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate degree awarded by colleges and universities upon completion of a course of study lasting three to six years (depending on the institution and academic discipline). The two most common bachelor's degrees are the Bachelor of Arts (BA) and the Bachelor of Science (BS or BSc). In some institutions and educational systems, certain bachelor's degrees can only be taken as graduate or postgraduate educations after a first degree has been completed, although more commonly the successful completion of a bachelor's degree is a prerequisite for further courses such as a master's or a doctorate. In countries with qualifications frameworks, bachelor's degrees are normally one of the major levels in the framework (sometimes two levels where non-honours and honours bachelor's degrees are considered separately). However, some qualifications titled bachelor's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hanover, New Hampshire
Hanover is a New England town, town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 United States census, 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory, and Hanover High School (New Hampshire), Hanover High School. The Appalachian Trail crosses the town, connecting with a number of trails and nature preserves. Most of the population resides in the Hanover (CDP), New Hampshire, Hanover census-designated place (CDP)—the main village of the town. Located at the junctions of New Hampshire routes New Hampshire Route 10, 10, New Hampshire Route 10A, 10A, and New Hampshire Route 120, 120, the Hanover CDP recorded a population of 9,078 people at the 2020 census. The town is part of the Lebanon–Claremont micropolitan area and also contains the smaller villages of Etna, New Hampshire, Etna and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brookline, Massachusetts
Brookline () is an affluent town in Norfolk County, Massachusetts, United States, and part of the Greater Boston, Boston metropolitan area. An exclave of Norfolk County, Brookline borders six of Boston's neighborhoods: Brighton, Boston, Brighton, Allston, Fenway–Kenmore, Mission Hill, Boston, Mission Hill, Jamaica Plain, and West Roxbury. The city of Newton, Massachusetts, Newton borders Brookline to the west. It is known for being the birthplace of John F. Kennedy. The land which comprises what is today Brookline was first settled in 1638 as a Hamlet (place), hamlet in Boston, known as Muddy River (as it was settled on the west side of the Muddy River (Massachusetts), river of the same name). It was incorporated as a separate town with the name of Brookline in 1705. In 1873, Brookline had a Boston–Brookline annexation debate of 1873, contentious referendum in which it voted to remain independent from Boston. The later annexations of Brighton, Boston, Brighton and West Roxbur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
YMCA
YMCA, sometimes regionally called the Y, is a worldwide youth organisation based in Geneva, Switzerland, with more than 64 million beneficiaries in 120 countries. It has nearly 90,000 staff, some 920,000 volunteers and 12,000 branches worldwide. It was founded in London on 6 June 1844 by George Williams (philanthropist), George Williams as the Young Men's Christian Association. The organisation's stated aim is to put Christian values into practice by developing a healthy body, mind, and spirit. From its inception, YMCA grew rapidly, ultimately becoming a worldwide movement founded on the principles of muscular Christianity. Local YMCAs deliver projects and services focused on youth development through a wide variety of youth activities, including providing athletic facilities, holding classes for a wide variety of skills, promoting Christianity, and humanitarian work. YMCA is a non-governmental federation, with each independent local YMCA affiliated with its national or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minnesota
Minnesota ( ) is a U.S. state, state in the Upper Midwestern region of the United States. It is bordered by the Canadian provinces of Manitoba and Ontario to the north and east and by the U.S. states of Wisconsin to the east, Iowa to the south, and North Dakota and South Dakota to the west. It is the List of U.S. states and territories by area, 12th-largest U.S. state in area and the List of U.S. states and territories by population, 22nd-most populous, with about 5.8 million residents. Minnesota is known as the "Land of 10,000 Lakes"; it has 14,420 bodies of fresh water covering at least ten acres each. Roughly a third of the state is Forest cover by state and territory in the United States, forested. Much of the remainder is prairie and farmland. More than 60% of Minnesotans (about 3.71 million) live in the Minneapolis–Saint Paul metropolitan area, known as the "Twin Cities", which is Minnesota's main Politics of Minnesota, political, Economy of Minnesota, economic, and C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
