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Antibiotic Resistant Bacteria
A list of antibiotic resistant bacteria is provided below. These bacteria have shown antibiotic resistance (or antimicrobial resistance). Gram positive ''Clostridioides difficile'' ''Clostridioides difficile'' is a nosocomial pathogen that causes diarrheal disease worldwide. Diarrhea caused by ''C. difficile'' can be life-threatening. Infections are most frequent in people who have had recent medical and/or antibiotic treatment. ''C. difficile'' infections commonly occur during hospitalization. According to a 2015 CDC report, ''C. difficile'' caused almost 500,000 infections in the United States per year. Associated with these infections were an estimated 15,000 deaths. The CDC estimates that ''C. difficile'' infection costs could amount to $3.8 billion over five years. ''C. difficile'' colitis is most strongly associated with fluoroquinolones, cephalosporins, carbapenems, and clindamycin. Some research suggests the overuse of antibiotics in the raising of livestock is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as inactive or latent tuberculosis. A small proportion of latent infections progress to active disease that, if left untreated, can be fatal. Typical symptoms of active TB are chronic cough with hemoptysis, blood-containing sputum, mucus, fever, night sweats, and weight loss. Infection of other organs can cause a wide range of symptoms. Tuberculosis is Human-to-human transmission, spread from one person to the next Airborne disease, through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with latent TB do not spread the disease. A latent infection is more likely to become active in those with weakened I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-nucleotide Polymorphism
In genetics and bioinformatics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), many publications do not apply such a frequency threshold. For example, a Guanine, G nucleotide present at a specific location in a reference genome may be replaced by an Adenine, A in a minority of individuals. The two possible nucleotide variations of this SNP – G or A – are called alleles. SNPs can help explain differences in susceptibility to a wide range of diseases across a population. For example, a common SNP in the Factor H, CFH gene is associated with increased risk of age-related macular degeneration. Differences in the severity of an illness or response to treatments may also be manifestations of genetic variations caused by SNPs. For example, two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Azithromycin
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throat, pneumonia, traveler's diarrhea, Sexually transmitted infection, STI and certain other gastroenteritis, intestinal infections. Along with other medications, it may also be used for malaria. It is Drug administration, administered by mouth, intravenously, into a vein, or into the eye drops, eye. Common side effects include nausea, vomiting, diarrhea and upset stomach. An allergic reaction, such as anaphylaxis, or a type of diarrhea caused by Clostridioides difficile infection, ''Clostridioides difficile'' is possible. Azithromycin causes drug-induced QT prolongation, QT prolongation that may cause life-threatening arrhythmias such as torsades de pointes. While some studies claim that no harm has been found with use during pregnancy, more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mucopurulent Discharge
Mucopurulent discharge is the emission or secretion of fluid containing mucus and pus (''muco-'' pertaining to ''mucus'' and ''purulent'' pertaining to ''pus'') from the eye, nose, cervix, vagina or other part of the body due to infection and inflammation. Types include: *In ophthalmology, mucopurulent discharge from the eyes, and caught in the eyelashes, is a hallmark sign of bacterial conjunctivitis. The normal buildup of tears, mucus, and dirt (compare rheum) that appears at the edge of the eyelids after sleep Sleep is a state of reduced mental and physical activity in which consciousness is altered and certain Sensory nervous system, sensory activity is inhibited. During sleep, there is a marked decrease in muscle activity and interactions with th ... is not mucopurulent discharge, as it does not contain pus. * Vaginal discharge References "Conjunctivitis: A Systematic Review of Diagnosis and Treatment" – NCBI Symptoms {{symptom-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urethritis
Urethritis is the inflammation of the urethra. The most common symptoms include painful or difficult urination and urethral discharge. It is a commonly treatable condition usually caused by infection with bacteria. This bacterial infection is often sexually transmitted, but not in every instance; it can be idiopathic, for example. Some incidence of urethritis can appear asymptomatic as well. Symptoms and signs Symptoms vary based on the cause of the diseases. For infectious causes of urethritis, symptoms may start a few weeks to several months after infection. Non-infectious causes of urethritis commonly show symptoms after a few days. Common symptoms include painful urination, continuous urge to urinate, itching, and urethral discharge. Additional symptoms vary based on sex. Men may experience blood in the urine or semen, itching, tenderness, or swelling of the penis, enlarged lymph nodes in the groin area, and/or pain with intercourse or ejaculation. Women may experience ab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urethra
The urethra (: urethras or urethrae) is the tube that connects the urinary bladder to the urinary meatus, through which Placentalia, placental mammals Urination, urinate and Ejaculation, ejaculate. The external urethral sphincter is a striated muscle that allows voluntary control over urination. The Internal urethral sphincter, internal sphincter, formed by the involuntary smooth muscles lining the bladder neck and urethra, receives its nerve supply by the Sympathetic nervous system, sympathetic division of the autonomic nervous system. The internal sphincter is present both in males and females. Structure The urethra is a fibrous and muscular tube which connects the urinary bladder to the external urethral meatus. Its length differs between the sexes, because it passes through the penis in males. Male In the human male, the urethra is on average long and opens at the end of the external urethral meatus. The urethra is divided into four parts in men, named after the lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycoplasma Genitalium
''Mycoplasma genitalium'' (also known as ''MG','' Mgen, or since 2018, ''Mycoplasmoides genitalium'') is a sexually transmitted, small and pathogenic bacterium that lives on the mucous epithelial cells of the urinary and genital tracts in humans. Medical reports published in 2007 and 2015 state that Mgen is becoming increasingly common. Resistance to multiple antibiotics, including the macrolide azithromycin, which until recently was the most reliable treatment, is becoming prevalent. The bacterium was first isolated from the urogenital tract of humans in 1981, and was eventually identified as a new species of '' Mycoplasma'' in 1983. It can cause negative health effects in men and women. It also increases the risk for HIV spread with higher occurrences in those previously treated with the azithromycin antibiotics. Symptoms of infection Mgen is a bacterium recognized for causing urethritis in both men and women along with cervicitis and pelvic inflammation in women ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, aci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extensively Drug-resistant Tuberculosis
Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB drugs. XDR-TB strains have arisen after the mismanagement of individuals with multidrug-resistant TB (MDR-TB). Almost one in four people in the world is infected with TB bacteria. Only when the bacteria become active do people become ill with TB. Bacteria become active as a result of anything that can reduce the person's immunity, such as HIV, advancing age, or some medical conditions. TB can usually be treated with a course of four standard, or first-line, anti-TB drugs (i.e., isoniazid, rifampin and any fluoroquinolone). If these drugs are misused or mismanaged, multidrug-resistant TB (MDR-TB) can develop. MDR-TB takes longer to treat with second-line drugs (i.e., amikacin, kanamycin, or capreomycin), which are more expensive and have more side-effects. XDR-TB can develop when these second-line drugs are also misused or mis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifampin
Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), ''Mycobacterium avium'' complex, leprosy, and Legionnaires' disease. It is almost always used together with other antibiotics with two notable exceptions: when given as a "preferred treatment that is strongly recommended" for latent TB infection; and when used as post-exposure prophylaxis to prevent ''Haemophilus influenzae'' type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time, measurements of liver enzymes and blood counts are recommended. Rifampicin may be given either by mouth or intravenously. Common side effects include nausea, vomiting, diarrhea, and loss of appetite. It often turns urine, sweat, and tears a red or orange color. Liver problems or allergic reactions may occur. It is part of the recommended treatment of active tuberculosis during ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis, it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis, it is often used alone. It may also be used for atypical types of mycobacteria, such as '' M. avium'', '' M. kansasii'', and '' M. xenopi''. It is usually taken by mouth, but may be used by injection into muscle. History After F. Raschig developed a method to synthesize hydrazine, Hans Meyer and his doctoral student at the German University in Prague Josef Mally studied hydrazides of pyridinecarboxylic acids. By reacting ethyl isonicotinate with hydrazine hydrate they obtained a compound which, after a recrystallization, had a melting point of 163°C. Despite their results published in 1912, its pharmaceutical properties weren't investigated for decades. In the 1940s French physicians discovered that nicotina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
