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John Vane
Sir John Robert Vane (29 March 1927 – 19 November 2004) was a British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. He was awarded the Nobel Prize in Physiology or Medicine in 1982 along with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances". Education and early life Born in Tardebigge, Worcestershire, John Vane was one of three children and grew up in suburban Birmingham. His father, Maurice Vane, was the son of Jewish Russian immigrants and his mother, Frances Vane, came from a Worcestershire farming family. He attended a local state school from age 5, before moving on to King Edward's School in Edgbaston, Birmingham. An early interest in chemistry was to prove the inspiration for studying the subject at the U ...
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Tardebigge
Tardebigge () is a village in Worcestershire, England. The village is most famous for the Tardebigge Locks, a flight of 30 canal locks that raise the Worcester and Birmingham Canal over over the Lickey Ridge. It lies in the county of Worcestershire, although it was also historically an exclave of Staffordshire or Warwickshire at different times in its history. Toponymy The name ''Tærdebicga'' has no likely meaning in Old English or Celtic; Eilert Ekwall simply says it is "unexplained". History Tardebigge was once a much greater township, which included much of Redditch, including the modern day town-centre. Its name was recorded twice in a will as Anglo-Saxon ''æt Tærdebicgan''. Records of the parish begin in the late 10th century. Tardebigge was bought by the Dean of Worcester for his Church from King Ethelred the Unready. In the later Dark Ages there were battles fought between Ethelred's son Edmund Ironside and the Cnut the Dane. In the 12th century, the ...
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Pharmacologist
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ...
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Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous Biological activity, bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered Pharmaceutical drug, pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanism of action, mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, drug interaction, interactions, chemical ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxfor ...
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Joshua Harold Burn
Joshua Harold Burn FRS (6 March 1892 – 13 July 1981) was an English pharmacologist and professor of pharmacology at Oxford University. Burn worked on the internal control of the body by the autonomic nervous system, carrying out seminal work on the release of noradrenaline from these nerves and introducing the controversial Burn-Rand hypothesis. The Nobel Laureate John Vane claimed "If anyone can be said to have moulded the subject of pharmacology around the world, it is he". Life Burn was born in Barnard Castle, County Durham, England.Joshua Harold Burn. 6 March 1892 – 13 July 1981 Edith Bülbring and J. M. Walker Page 47 of 44–89 He was educated at Barnard Castle School. Burn entered Emmanuel College, Cambridge in 1909 where he read the Natural Sciences Tripos. He specialised in physiology for Part II. His tutor was Frederick Gowland Hopkins. After receiving his BA he was awarded a research grant by Emmanuel College and a Michael Foster Studentship by the universit ...
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Maurice Stacey
Maurice Stacey CBE FRS FRIC (8 April 1907 – 9 October 1994) was a British chemist who worked alongside Sir Norman Haworth to artificially synthesize Vitamin C. Maurice Stacey was born on 8 April 1907 in Moreton, Shropshire. Stacey was educated at Adams Grammar School, Newport and graduated from Birmingham University with the degrees of BSc, PhD and DSc. Stacey began his career at Birmingham University as a demonstrator in chemistry in 1929. He was leader under Sir Norman Haworth of the Birmingham University team which synthesised Vitamin C in 1932. It was Stacey who personally isolated synthetic vitamin C. Stacey was Beit Memorial Fellow for Medical Research at the London School of Tropical Medicine from 1933 to 1937. Stacey returned to Birmingham University in 1937 as lecturer in chemistry and then reader in biological chemistry. Stacey was professor of chemistry at Birmingham University from 1946 to 1956. He was Mason Professor and head of the Department of Chemistry at B ...
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Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a natural science that covers the elements that make up matter to the compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a reaction with other substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both basic and applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth ( botany), the formation of igneous rocks ( geology), how atmospheric ozone is formed and how environmental pollutants are degraded ( ecology), the properties of the soil on the moon ( cosmochemistry), how medications work ( pharmacology), and how to collec ...
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Birmingham
Birmingham ( ) is a City status in the United Kingdom, city and metropolitan borough in the metropolitan county of West Midlands (county), West Midlands in England. It is the second-largest city in the United Kingdom with a population of 1.145 million in the city proper, 2.92 million in the West Midlands (county), West Midlands metropolitan county, and approximately 4.3 million in the Birmingham metropolitan area, wider metropolitan area. It is the ESPON metropolitan areas in the United Kingdom, largest UK metropolitan area outside of London. Birmingham is known as the second city of the United Kingdom. Located in the West Midlands (region), West Midlands region of England, approximately from London, Birmingham is considered to be the social, cultural, financial and commercial centre of the Midlands. Distinctively, Birmingham only has small rivers flowing through it, mainly the River Tame, West Midlands, River Tame and its tributaries River Rea and River Cole, West Midlands ...
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Edgbaston
Edgbaston () is an affluent suburban area of central Birmingham, England, historically in Warwickshire, and curved around the southwest of the city centre. In the 19th century, the area was under the control of the Gough-Calthorpe family and the Gillott family who refused to allow factories or warehouses to be built in Edgbaston, thus making it attractive for the wealthier residents of the city. It then came to be known as "where the trees begin". One of these private houses is grade one listed and open to the public. The majority of Edgbaston that falls under the B15 postcode finds itself being part of the Calthorpe Estate. The estate is an active conservation area, and it is here that the areas most prized properties are situated. The exclusivity of Edgbaston is down to its array of multi-million listed Georgian and Victorian villas, making it one of the most expensive postcodes outside of London. Edgbaston boasts facilities such as Edgbaston Cricket Ground, a Test m ...
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King Edward's School, Birmingham
King Edward's School (KES) is an independent day school for boys in the British public school tradition, located in Edgbaston, Birmingham. Founded by King Edward VI in 1552, it is part of the Foundation of the Schools of King Edward VI in Birmingham. It is a member of the Headmasters' and Headmistresses' Conference. As of 2021, King Edward's School was ranked as one of the top 10 International Baccalaureate schools in the United Kingdom and amongst the top 25 in the world. In 2020, the '' Tatler School Guide'' described the school as “academically elite,” going on to note that it is “in the process of upping its already sky-high intellectual ante ..with top-of-the-range sporting facilities and a raft of extracurricular activities ..it comes as no surprise that leavers head off to a shining constellation of universities.” It shares its site and is twinned with King Edward VI High School for Girls (KEHS). Whilst the two schools are managed separately, dramatic arts, s ...
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Prostaglandin
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from the fatty acid arachidonic acid. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are a subclass of eicosanoids and of the prostanoid class of fatty acid derivatives. The structural differences between prostaglandins account for their different biological activities. A given prostaglandin may have different and even opposite effects in different tissues in some cases. The ability of the same prostaglandin to stimulate a reaction in one tissue and inhibit the same reaction in another tissue is determined by the type of receptor to which the prostaglandin binds. They act as autocrine or paracrine factors with their target cells present in the immediate vicinity of the site of their secreti ...
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Bengt I
Bengt may refer to: People In arts, entertainment and media Actors * Bengt Djurberg (1898–1941), Swedish actor and singer * Bengt Ekerot (1920–1971), Swedish actor and director * Bengt Eklund (1925–1998), Swedish actor * Bengt Logardt (1914–1994), Swedish actor, screenwriter and film director * Bengt Nilsson (actor) (born 1954), Swedish actor Journalists and writers * Bengt Feldreich (1925-2019), Swedish journalist and teacher * Bengt Frithiofsson (born 1939), Swedish wine writer * Bengt Lidner (1757–1793), Swedish poet * Bengt Linder (1929–1985), Swedish writer and journalist * Bengt Magnusson (born 1950), Swedish journalist and a TV presenter * Bengt Pohjanen (born 1944), Swedish author, translator and priest In music * Bengt Berger (born 1942), Swedish jazz drummer, composer and producer * Bengt Calmeyer, Swedish musician in the band Turbonegro * Bengt Djurberg (1898–1941), Swedish actor and singer * Bengt Forsberg (born 1952), Swedish concert pianist * ...
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