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Michele Vendruscolo
Michele Vendruscolo (born in Udine, 23 July 1966) is an Italian British physicist working in the UK, noted for his theoretical and experimental work on protein folding, misfolding and aggregation. Education Vendruscolo is a graduate in physics of the University of Trieste (Italy). He received a Master of Science (MSc) and a PhD in condensed matter physics at the International School for Advanced Studies in Trieste, Italy. He then worked as a postdoctoral researcher, at the Weizmann Institute, Israel with Eytan Domany as a supervisor (1996–1998) and at the University of Oxford (1999–2001) under the supervision of Chris Dobson. Research and career He was appointed as an independent academic at the University of Cambridge as a Royal Society University Research Fellow (2001), as a Lecturer (2006), and then as a Reader (2008) in Theoretical Chemical Biology. He is now Professor of Biophysics at the same university. He is also Director of Chemistry of Health, and Co-Director of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Udine
Udine ( , ; fur, Udin; la, Utinum) is a city and ''comune'' in north-eastern Italy, in the middle of the Friuli Venezia Giulia region, between the Adriatic Sea and the Alps (''Alpi Carniche''). Its population was 100,514 in 2012, 176,000 with the urban area. Names and etymology Udine was first attested in medieval Latin records as ''Udene'' in 983 and as ''Utinum'' around the year 1000. The origin of the name ''Udine'' is unclear. It has been tentatively suggested that the name may be of pre-Roman origin, connected with the Indo-European root *''odh-'' 'udder' used in a figurative sense to mean 'hill'. The Slovene name ''Videm'' (with final -''m'') is a hypercorrection of the local Slovene name ''Vidan'' (with final -''n''), based on settlements named ''Videm'' in Slovenia. The Slovene linguist Pavle Merkù characterized the Slovene form ''Videm'' as an "idiotic 19th-century hypercorrection." History Udine is the historical capital of Friuli. The area has been inhabited ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trieste
Trieste ( , ; sl, Trst ; german: Triest ) is a city and seaport in northeastern Italy. It is the capital city, and largest city, of the autonomous region of Friuli Venezia Giulia, one of two autonomous regions which are not subdivided into provinces. Trieste is located at the head of the Gulf of Trieste, on a narrow strip of Italian territory lying between the Adriatic Sea and Slovenia; Slovenia lies approximately east and southeast of the city, while Croatia is about to the south of the city. The city has a long coastline and is surrounded by grassland, forest, and karstic areas. The city has a subtropical climate, unusual in relation to its relatively high latitude, due to marine breezes. In 2022, it had a population of about 204,302. Capital of the autonomous region of Friuli Venezia Giulia and previously capital of the Province of Trieste, until its abolition on 1 October 2017. Trieste belonged to the Habsburg monarchy from 1382 until 1918. In the 19th century t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PNAS
''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Sciences, published since 1915, and publishes original research, scientific reviews, commentaries, and letters. According to ''Journal Citation Reports'', the journal has a 2021 impact factor of 12.779. ''PNAS'' is the second most cited scientific journal, with more than 1.9 million cumulative citations from 2008 to 2018. In the mass media, ''PNAS'' has been described variously as "prestigious", "sedate", "renowned" and "high impact". ''PNAS'' is a delayed open access journal, with an embargo period of six months that can be bypassed for an author fee ( hybrid open access). Since September 2017, open access articles are published under a Creative Commons license. Since January 2019, ''PNAS'' has been online-only, although print issues are av ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Oligomer
Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure of proteins which are themselves composed of two or more smaller protein chains (also referred to as subunits). Protein quaternary structure describes the number and arrangement of multiple folded protein subunits in a multi-subunit complex. It includes organizations from simple dimers to large homooligomers and complexes with defined or variable numbers of subunits. In contrast to the first three levels of protein structure, not all proteins will have a quaternary structure since some proteins function as single units. Protein quaternary structure can also refer to biomolecular complexes of proteins with nucleic acids and other cofactors. Description and examples Many proteins are actually assemblies of multiple polypeptide chains. The quaternary structure refers to the number and arrangement of the protein subunits wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more products, which usually have properties different from the reactants. Reactions often consist of a sequence of individual sub-steps, the so-called elementary reactions, and the information on the precise co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transition States
In chemistry, the transition state of a chemical reaction is a particular configuration along the reaction coordinate. It is defined as the state corresponding to the highest potential energy along this reaction coordinate. It is often marked with the double dagger ‡ symbol. As an example, the transition state shown below occurs during the SN2 reaction of bromoethane with a hydroxide anion: The activated complex of a reaction can refer to either the transition state or to other states along the reaction coordinate between reactants and products, especially those close to the transition state.Peter Atkins and Julio de Paula, ''Physical Chemistry'' (8th ed., W.H. Freeman 2006), p.809 According to the transition state theory, once the reactants have passed through the transition state configuration, they always continue to form products. History of concept The concept of a transition state has been important in many theories of the rates at which chemical reactions o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centre For Misfolding Diseases
The Yusuf Hamied Department of Chemistry is the University of Cambridge's chemistry department. It was formed from a merger in the early 1980s of two separate departments that had moved into the Lensfield Road building decades earlier: the Department of Physical Chemistry (originally led by Professor Ronald Norrish FRS, Nobel Laureate; the department was previously located near the Old Cavendish in Free School Lane - see photo) and the Department of Chemistry (that included theoretical chemistry and which was led by Lord (Alexander) Todd FRS, Nobel Laureate) respectively. Research interests in the department cover a broad of chemistry ranging from molecular biology to geophysics. The department is located on the Lensfield Road, next to the Panton Arms on the South side of Cambridge. In December 2020, it was renamed for 30 years in recognition of a donation from Dr Yusuf Hamied, an alumnus of the department. Research The Department's research is organised around five Research Int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892. Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reader (academic Rank)
The title of reader in the United Kingdom and some universities in the Commonwealth of Nations, for example India, Australia and New Zealand, denotes an appointment for a senior academic with a distinguished international reputation in research or scholarship. In the traditional hierarchy of British and other Commonwealth universities, reader (and principal lecturer in the new universities) are academic ranks above senior lecturer and below professor, recognising a distinguished record of original research. Reader is similar to a professor without a chair, similar to the distinction between ''professor extraordinarius'' and ''professor ordinarius'' at some European universities, professor and chaired professor in Hong Kong and "professor name" (or associate professor) and chaired professor in Ireland. Readers and professors in the UK would correspond to full professors in the United States.Graham WebbMaking the most of appraisal: career and professional development planning fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society University Research Fellow
__NOTOC__ The Royal Society University Research Fellowship (URF) is a research fellowship awarded to outstanding early career scientists in the United Kingdom who are judged by the Royal Society to have the potential to become leaders in their field."University Research Fellowship" Royal Society The research fellowship funds all areas of research in including , s and |
University Of Cambridge
, mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Scholars of the University of Cambridge , type = Public research university , endowment = £7.121 billion (including colleges) , budget = £2.308 billion (excluding colleges) , chancellor = The Lord Sainsbury of Turville , vice_chancellor = Anthony Freeling , students = 24,450 (2020) , undergrad = 12,850 (2020) , postgrad = 11,600 (2020) , city = Cambridge , country = England , campus_type = , sporting_affiliations = The Sporting Blue , colours = Cambridge Blue , website = , logo = University of Cambridge log ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the world's second-oldest university in continuous operation. It grew rapidly from 1167 when Henry II banned English students from attending the University of Paris. After disputes between students and Oxford townsfolk in 1209, some academics fled north-east to Cambridge where they established what became the University of Cambridge. The two English ancient universities share many common features and are jointly referred to as ''Oxbridge''. Both are ranked among the most prestigious universities in the world. The university is made up of thirty-nine semi-autonomous constituent colleges, five permanent private halls, and a range of academic departments which are organised into four divisions. All the colleges are self-governing institutions within the university, each controlling ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
