Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S.
subsidiary
A subsidiary, subsidiary company, or daughter company is a company (law), company completely or partially owned or controlled by another company, called the parent company or holding company, which has legal and financial control over the subsidia ...
of the German company
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer su ...
, which was founded in 1851 by
Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering (31 May 1824 – 27 December 1889) was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during W ...
. As a result of
nationalization
Nationalization (nationalisation in British English)
is the process of transforming privately owned assets into public assets by bringing them under the public ownership of a national government or state. Nationalization contrasts with p ...
, it became an independent company. In 1971, the Schering Corporation merged with Plough, Inc. (founded by Memphis-based entrepreneur
Abe Plough
Abe Plough (December 27, 1891 – September 14, 1984) was an American business owner who is best known for founding Plough Inc.
Plough Inc. merged with the German company Schering Corporation in 1971, now Schering-Plough a pharmaceutical company.
...
in 1908
) to form Schering-Plough. On November 4, 2009
Merck & Co. merged with Schering-Plough with the new company taking the name of Merck & Co.
Schering-Plough manufactured several pharmaceutical
drugs
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via inhalation, injection, smoking, ingestio ...
, the most well-known of which were the
allergy
Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include Allergic rhinitis, hay fever, Food allergy, food al ...
drugs
Claritin
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in whic ...
and
Clarinex
Desloratadine sold under the brand name Aerius among others, is a tricyclic H1 inverse agonist that is used to treat allergies. It is an active metabolite of loratadine.
It was patented in 1984 and came into medical use in 2001. It was br ...
, an anti-
cholesterol
Cholesterol is the principal sterol of all higher animals, distributed in body Tissue (biology), tissues, especially the brain and spinal cord, and in Animal fat, animal fats and oils.
Cholesterol is biosynthesis, biosynthesized by all anima ...
drug
Vytorin
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Ezetimibe reduces blood cho ...
, and a
brain tumor
A brain tumor (sometimes referred to as brain cancer) occurs when a group of cells within the Human brain, brain turn cancerous and grow out of control, creating a mass. There are two main types of tumors: malignant (cancerous) tumors and benign ...
drug
Temodar. These are now available from Merck & Co.
Schering-Plough also owned and operated the major foot care brand name
Dr. Scholl's and the skin care line
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original product dates to 1944, when pharmacist Benjamin Green inv ...
. These also became a part of the new company.
, Schering-Plough had 1.4% market share in the U.S., placing it seventeenth in the top twenty pharmaceutical corporations by sales compiled by
IMS Health
IMS Health was an American company that provided information, services and technology for the healthcare industry. IMS stood for Intercontinental Medical Statistics. It was the largest vendor of U.S. physician prescribing data. IMS Health was fou ...
.
Schering-Plough was a full member of the
(EFPIA), a membership which is also maintained by the new Merck & Co.
History
Pharmaceuticals and consumer products
Schering was founded in 1851 by
Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering (31 May 1824 – 27 December 1889) was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during W ...
as
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer su ...
in
Germany
Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total popu ...
.
Plough, Incorporated was founded by the
Memphis, Tennessee
Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Situated along the Mississippi River, it had a population of 633,104 at the 2020 United States census, 2020 census, making it the List of municipalities in Tenne ...
area entrepreneur Abe Plough (1892–1984) in 1908. He borrowed $125 from his father to start the business at age sixteen. As a one-man business, he mixed "Plough's Antiseptic Healing Oil," a "sure cure for any ill of man or beast," and sold it off a horse-drawn buggy.
Plough's acquisitions included St Joseph's Aspirin for children,
Maybelline
Maybelline New York (formerly The Maybelline Company and Mabelline and Co.), trading as and commonly known as simply Maybelline ( ), is an American multinational cosmetics, skin care, perfume, and personal care company, based in New York City. ...
cosmetics, and
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original product dates to 1944, when pharmacist Benjamin Green inv ...
skin care products. Plough also had a broadcasting division, operating radio stations in
Atlanta, Georgia
Atlanta ( ) is the List of capitals in the United States, capital and List of municipalities in Georgia (U.S. state), most populous city in the U.S. state of Georgia (U.S. state), Georgia. It is the county seat, seat of Fulton County, Georg ...
(
WPLO-AM &
FM);
Baltimore, Maryland
Baltimore is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland. With a population of 585,708 at the 2020 United States census, 2020 census and estimated at 568,271 in 2024, it is the List of United States ...
(
WCAO-AM &
FM);
Boston, Massachusetts
Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeas ...
(
WCOP-AM &
FM);
Chicago, Illinois
Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
(
WJJD-AM &
FM); and
Memphis, Tennessee
Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Situated along the Mississippi River, it had a population of 633,104 at the 2020 United States census, 2020 census, making it the List of municipalities in Tenne ...
(
WMPS-AM &
FM).
Following the entry of the
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
into
World War II
World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
in 1941, U.S. President
Franklin Delano Roosevelt
Franklin Delano Roosevelt (January 30, 1882April 12, 1945), also known as FDR, was the 32nd president of the United States, serving from 1933 until his death in 1945. He is the longest-serving U.S. president, and the only one to have served ...
ordered
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer su ...
's U.S. assets be seized. These became the Schering Corporation. The company was placed under a government administratorship until 1952, when it was released, and its assets sold to the private sector.
In 1957, Schering acquired White Laboratories.
In 1971, the Schering Corporation merged with Plough, Inc. At the time of the merger, Abe Plough became Chairman of the combined company.
In 2000, Schering-Plough bought a new campus in
Summit, New Jersey
Summit is the northernmost City (New Jersey), city of Union County, New Jersey, Union County, in the U.S. state of New Jersey, located within the New York metropolitan area. Situated on a ridge in north Jersey, northern–central Jersey, centra ...
from
Novartis
Novartis AG is a Swiss multinational corporation, multinational pharmaceutical company, pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by re ...
.
On March 12, 2007, Schering-Plough Corp. purchased
Organon BioSciences, the drug unit of Netherlands-based
Akzo Nobel
Akzo Nobel N.V., stylised as AkzoNobel, is a Dutch multinational company which creates paints and performance coatings for both industry and consumers worldwide. Headquartered in Amsterdam, the company has activities in more than 150 countries ...
, for $14.4 billion, giving the US pharmaceutical company an array of women's health products and numerous late-stage pipelines of experimental medicines.
''
Organon
The ''Organon'' (, meaning "instrument, tool, organ") is the standard collection of Aristotle's six works on logical analysis and dialectic. The name ''Organon'' was given by Aristotle's followers, the Peripatetics, who maintained against the ...
'' itself was founded in 1923 by Dr. Saal van Zwanenberg, the president of Zwanenberg's Slachterijen en Fabrieken.
On November 4, 2009 Schering-Plough merged with
Merck & Co. and through a
reverse merger
A reverse takeover (RTO), reverse merger, or reverse IPO is the acquisition of a public company by a private company so that the private company can bypass the lengthy and complex process of going public. Sometimes, conversely, the public compa ...
, Merck became a subsidiary of Schering-Plough, which renamed itself Merck.
Animal health
Coopers Animal Health
One of Schering-Plough's plants, in
Upper Hutt, New Zealand
Upper Hutt () is a city in the Wellington Region of New Zealand and one of the four cities that constitute the Wellington#Wellington metropolitan area, Wellington metropolitan area.
History
Upper Hutt is in an area originally known as Orongo ...
was the largest single site for the production of veterinary
vaccines
A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an ag ...
in the world. This was primarily because
New Zealand
New Zealand () is an island country in the southwestern Pacific Ocean. It consists of two main landmasses—the North Island () and the South Island ()—and List of islands of New Zealand, over 600 smaller islands. It is the List of isla ...
's isolation has formed a natural
quarantine
A quarantine is a restriction on the movement of people, animals, and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have bee ...
, leaving the country free of
rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. It was historically referred to as hydrophobia ("fear of water") because its victims panic when offered liquids to drink. Early symptoms can include fever and abn ...
,
foot and mouth
Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious disease, infectious and sometimes fatal virus (biology), viral disease that primarily affects even-toed ungulates, including domestic and wild Bovidae, bovids. The vir ...
,
scrapie
Scrapie () is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be caused by a prion. Scrapie has been known sin ...
,
bovine spongiform encephalopathy
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and always fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of th ...
, and many other livestock diseases. It formerly had
echinococcosis
Echinococcosis is a parasitic disease caused by tapeworms of the ''Echinococcus'' type. The two main types of the disease are ''cystic echinococcosis'' and ''alveolar echinococcosis''. Less common forms include ''polycystic echinococcosis'' an ...
, but this has been eradicated. The site was known locally as Coopers Animal Health, a trademark which originated in the 1850s with a British company,
Cooper & Nephews; the Coopers brand name was still in use by Schering-Plough in Australia, but not elsewhere.
Intervet
As a result of the acquisition of Organon BioSciences, Schering-Plough bolstered its animal health business with the
Akzo Nobel
Akzo Nobel N.V., stylised as AkzoNobel, is a Dutch multinational company which creates paints and performance coatings for both industry and consumers worldwide. Headquartered in Amsterdam, the company has activities in more than 150 countries ...
subsidiary Intervet, obtained control of the active pharmaceutical ingredient manufacturer,
Diosynth
FUJIFILM Diosynth Biotechnologies, abbreviated and often referred to as FDB, is a biopharmaceutical contract manufacturing organization that develops manufacturing processes and manufactures active ingredients and provides fill and finish servic ...
and gained access to human vaccine production through the subsidiary Nobilon. The three companies comprising Organon BioSciences were Organon, Diosynth, and Intervet.
HomeAgain continues to use the Intervet name owned by Merck.
Merck Animal Health, MSD Animal Health
After the merger of Schering-Plough with Merck the animal health division was still known as Intervet/Schering-Plough Animal Health. A merger of Merial and Intervet/Schering-Plough was planned in 2010 but was abandoned in March 2011. On June 29, 2011, the company announced that the animal health division would now be known as Merck Animal Health in the United States and Canada; it is now called MSD Animal Health elsewhere in the world.
Chief executives
Medical products
Prescription products
*Bridion (
sugammadex
Sugammadex, sold under the brand name Bridion, is a medication for the reversal of neuromuscular blockade induced by rocuronium and vecuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). It is marketed by ...
)
*Cerazette
*
Desloratadine
Desloratadine sold under the brand name Aerius among others, is a tricyclic H1 antagonist, H1 inverse agonist that is used to treat allergy, allergies. It is an active metabolite of loratadine.
It was patented in 1984 and came into medical u ...
:
antihistamine
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides ...
branded ''Clarinex''
*Esmeron/Zemuron (
rocuronium
Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation for surgery o ...
)
*Famvir (
Famciclovir
Famciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is mark ...
): for
Shingles
Shingles, also known as herpes zoster or zona, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. T ...
(herpes zoster) treatment, developed by
Novartis
Novartis AG is a Swiss multinational corporation, multinational pharmaceutical company, pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by re ...
*Intron A & PEG-Intron
Interferon alfa-2b
Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and produced recombinantly in ''E. coli'' in the laboratory of Charles Weissmann at the Universi ...
: for treatment of
hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection period, people often have mild or no symptoms. Early symptoms can include ...
*Levitra (
vardenafil
Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. It is a PDE5 inhibitor. It is taken by mouth.
Medical uses
Vardenafil's indications and contraindications are the same ...
): Erectile-dysfunction drug; co-marketed with
Bayer
Bayer AG (English: , commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and is one of the largest pharmaceutical companies and biomedical companies in the world. Headquartered in Leverkusen, Bayer' ...
, and
GlaxoSmithKline
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers an ...
*Livial (
tibolone
Tibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. The medication is available alone and is not formulated o ...
)
*Marvelon/Desogen
*Nasonex and Asmanex (
Mometasone furoate
Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. Specifically it is used to prevent rather than treat asthma attacks. It can be ...
)
*Noxafil (
posaconazole
Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication.
It was approved for medical use in the European Union in October 2005, and in the United States in September 2006. It is available as a generic ...
)
*NuvaRing
*Puregon/Follistim
*
Quazepam
Quazepam, sold under the brand name Doral among others, is a relatively long-acting benzodiazepine derivative drug developed by the Schering Corporation in the 1970s. Quazepam is used for the treatment of insomnia, including sleep induction ...
(Doral)
*Remeron/Remeron SolTab (
mirtazapine
Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant, atypical tetracyclic antidepressant, and as such is used primarily to treat Depression (mood), depression. Its effects may take up to four weeks but ca ...
)
*Remicade (
infliximab
Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing ...
)
*Suboxone (
Buprenorphine
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous a ...
/Naloxone)
*Temodar (
temozolomide
Temozolomide, sold under the brand name Temodar among others, is an anticancer medication used to treat brain tumors such as glioblastoma and anaplastic astrocytoma. Text was copied from this source which is copyright European Medicines Agency ...
)
*Vytorin (
ezetimibe/simvastatin
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Ezetimibe reduces blood chole ...
): Cholesterol-lowering combination drug
*Zetia (
ezetimibe
Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred ...
): Cholesterol-lowering drug
Over-the-counter products (Most products sold to
Bayer
Bayer AG (English: , commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and is one of the largest pharmaceutical companies and biomedical companies in the world. Headquartered in Leverkusen, Bayer' ...
, except
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original product dates to 1944, when pharmacist Benjamin Green inv ...
)
*
Afrin: A
nasal spray
Nasal sprays are used to deliver medications Route of administration#Local, locally in the nasal cavities or systemic administration, systemically. They are used locally for conditions such as nasal congestion and allergic rhinitis. In some sit ...
decongestant
*Claritin (
loratadine
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in whic ...
): An
antihistamine
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides ...
which has less risk of causing
drowsiness
Somnolence (alternatively sleepiness or drowsiness) is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia). It has distinct meanings and causes. It can refer to the usual state preceding falling asleep ...
*Correctol: A
stimulant laxative
Laxatives, purgatives, or aperients are substances that loosen stools and increase bowel movements. They are used to treat and prevent constipation.
Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubri ...
incorporating
dioctyl sodium sulfosuccinate
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS).
Salts of this anion, especially docusate sodium, are widely used in medicine as an emo ...
and yellow
phenolphthalein
Phenolphthalein ( ) is a chemical compound with the chemical formula, formula carbon, C20hydrogen, H14oxygen, O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in ...
*
Coricidin
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold combination drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (a first-genera ...
: A
palliative
Palliative care (from Latin root "to cloak") is an interdisciplinary medical care-giving approach aimed at optimizing quality of life and mitigating or reducing suffering among people with serious, complex, and often terminal illnesses. Man ...
remedy for the
common cold
The common cold, or the cold, is a virus, viral infectious disease of the upper respiratory tract that primarily affects the Respiratory epithelium, respiratory mucosa of the human nose, nose, throat, Paranasal sinuses, sinuses, and larynx. ...
, targeted towards individuals with
high blood pressure
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major ri ...
*
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original product dates to 1944, when pharmacist Benjamin Green inv ...
: sunscreens
*
Bain de Soleil
Bain de Soleil was an American brand of sunscreen that was produced by Bayer.
The brand was known for low- SPF products that were typically marketed to women seeking skin tanning. It was affiliated with the Coppertone brand. The name Bain de So ...
: sunscreen
*Drixoral
*Solarcaine: Sunburn relief
*
Zinka: Colored sunscreen
Veterinary products
*
Home Again Pet Recovery System: HomeAgain is an advanced pet identification and retrieval system.
*
Zubrin: A non-steroidal anti-inflammatory drug (
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
) for the treatment of
osteoarthritis
Osteoarthritis is a type of degenerative joint disease that results from breakdown of articular cartilage, joint cartilage and underlying bone. A form of arthritis, it is believed to be the fourth leading cause of disability in the world, affect ...
in dogs.
*
Mometamax: Is indicated for the treatment of
canine acute externa and
chronic otitis externa associated with
yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
(
Malassezia pachydermatis, formerly
Pityrosporum canis) and/or
bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
susceptible to
gentamicin
Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis amo ...
. It contains the strongest steroid (
Mometasone furoate
Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. Specifically it is used to prevent rather than treat asthma attacks. It can be ...
) in Veterinary Medicine.
*
Eclipse Vaccines: Attenuated modified live feline vaccines available in a multitude of
antigen
In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response.
...
combinations.
*
Galaxy Vaccines
A galaxy is a Physical system, system of stars, stellar remnants, interstellar medium, interstellar gas, cosmic dust, dust, and dark matter bound together by gravity. The word is derived from the Ancient Greek, Greek ' (), literally 'milky', ...
: Canine vaccines available in a multitude of
antigen
In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response.
...
combinations.
*
Optimmune: Ophthalmic ointment (ciclosporin) for the treatment of Pannis and
Keratoconjunctivitis sicca
Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes. Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes. Symptoms range from mild and occas ...
in dogs.
*
Orbax
Orbifloxacin (brand name Orbax) is a fluoroquinolone antibiotic which is approved for use in dogs, marketed by Schering-Plough Animal Health.
See also
* Quinolone
Quinolone may refer to:
* 2-Quinolone
* 4-Quinolone
* Quinolone antibiotic
...
: Trade name for
orbifloxacin
Orbifloxacin (brand name Orbax) is a fluoroquinolone antibiotic which is approved for use in dogs, marketed by Schering-Plough Animal Health.
See also
* Quinolone
Quinolone may refer to:
* 2-Quinolone
* 4-Quinolone
* Quinolone antibiotic
...
, a
fluoroquinolone
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as well ...
.
*
Otomax: Is indicated for the treatment of
canine acute otitis externa and
chronic otitis externa associated with
yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
(
Malassezia pachydermatis, formerly
Pityrosporum canis) and/or
bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
susceptible to
gentamicin
Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis amo ...
. It contains betamethasone valerate as an anti-inflammatory.
*
Banamine: A non-steroidal anti-inflammatory drug (
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
) used in horses, cattle and swine in different parts of the world.
*
Estrumate: A synthetic
prostaglandin
Prostaglandins (PG) are a group of physiology, physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals. Prostaglandins have been found in almost every Tissue (biology), tissue in humans and ot ...
used in reproduction of cattle.
*
Trivetrin:
Trimethoprin sulfate for the treatment of cattle and swine.
*Nuflor-Florfenicol-for treatment of
bovine respiratory disease
Bovine respiratory disease (BRD) is the most common and economically devastating infectious disease affecting beef cattle in the world. It is a complex, bacterial or viral infection that causes pneumonia in calves which can be fatal. It also aff ...
, foot rot and control of respiratory disease in cattle at high risk of developing bovine respiratory disease.
Exercise drug
Schering-Plough also received much publicity for a drug
AICAR which mimics the effects of exercise, having especially potent effects when used alongside another drug
GW1516 developed by
GlaxoSmithKline
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers an ...
.
Collaborative research
In addition to internal research and development activities Schering-Plough was also involved in publicly funded collaborative research projects, with other industrial and academic partners. One example in
non-clinical safety assessment was the
InnoMed PredTox.
Controversy
In 2004, Schering-Plough was accused of marketing gimmicks and payoffs to doctors for prescribing the company's pharmaceutical products.
Schering-Plough entered a
consent decree
A consent decree is an agreement or settlement that resolves a dispute between two parties without admission of guilt (in a criminal case) or liability (in a civil case). Most often it is such a type of settlement in the United States. The ...
with the FDA on March 6, 2002 due to manufacturing issues with its albuterol inhaler. It was ordered to pay $500 million US dollars to the US Treasury.
References
External links
Yahoo! - Schering-Plough Corporation Company Profile
{{Authority control
Merck & Co.
1971 establishments in New Jersey
2009 mergers and acquisitions
2009 disestablishments in New Jersey
American companies established in 1971
Companies based in Union County, New Jersey
Companies formerly listed on the New York Stock Exchange
Defunct companies based in New Jersey
Defunct pharmaceutical companies of the United States
Pharmaceutical companies established in 1971
Pharmaceutical companies disestablished in 2009
Pharmaceutical companies based in New Jersey
American corporate subsidiaries