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Mosquito control manages the population of
mosquito Mosquitoes, the Culicidae, are a Family (biology), family of small Diptera, flies consisting of 3,600 species. The word ''mosquito'' (formed by ''Musca (fly), mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mos ...
es to reduce their damage to human health, economies, and enjoyment. Control strategies range from habitat modification and chemical insecticides to biological agents and mechanical traps.
Climate change Present-day climate change includes both global warming—the ongoing increase in Global surface temperature, global average temperature—and its wider effects on Earth's climate system. Climate variability and change, Climate change in ...
, artificial intelligence (AI), and community participation are increasingly shaping mosquito management today. Rising global temperatures have expanded mosquito habitats and disease risks, prompting new surveillance tools such as AI-enabled robots and community-led education programs to play key roles in reducing breeding grounds and tracking mosquito populations. Mosquito-control operations are targeted to multiple problems: * Nuisance mosquitoes bother people around homes or in parks and recreational areas; * Economically important mosquitoes reduce real estate values, adversely affect
tourism Tourism is travel for pleasure, and the Commerce, commercial activity of providing and supporting such travel. World Tourism Organization, UN Tourism defines tourism more generally, in terms which go "beyond the common perception of tourism as ...
and related business interests, or negatively impact
livestock Livestock are the Domestication, domesticated animals that are raised in an Agriculture, agricultural setting to provide labour and produce diversified products for consumption such as meat, Egg as food, eggs, milk, fur, leather, and wool. The t ...
or
poultry Poultry () are domesticated birds kept by humans for the purpose of harvesting animal products such as meat, Eggs as food, eggs or feathers. The practice of animal husbandry, raising poultry is known as poultry farming. These birds are most typ ...
production; * Public health is the focus when mosquitoes are vectors, or transmitters, of infectious
disease A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...
. * Mosquito-borne diseases can threaten
endangered species An endangered species is a species that is very likely to become extinct in the near future, either worldwide or in a particular political jurisdiction. Endangered species may be at risk due to factors such as habitat loss, poaching, inv ...
. Disease organisms transmitted by mosquitoes include
West Nile virus West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever. It is a member of the family ''Flaviviridae'', from the genus ''Flavivirus'', which also contains the Zika virus, dengue virus, and yellow fever virus. The virus ...
, Saint Louis encephalitis virus, Eastern equine encephalomyelitis virus, Everglades virus, Highlands J virus, La Crosse Encephalitis virus in the United States;
dengue fever Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. Asymptomatic infections are uncommon, mild cases happen frequently; if symptoms appear, they typically begin 3 to 14 days after i ...
, yellow fever, Ilheus virus,
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
,
Zika virus Zika virus (ZIKV; pronounced or ) is a member of the virus family ''Flaviviridae''. It is spread by daytime-active ''Aedes'' mosquitoes, such as '' A. aegypti'' and '' A. albopictus''. Its name comes from the Ziika Forest of Uganda, where ...
and
filariasis Filariasis is a filarial infection caused by parasitic nematodes (roundworms) spread by different vectors. They are included in the list of neglected tropical diseases. The most common type is lymphatic filariasis caused by three species o ...
in the American tropics; Rift Valley fever, ''
Wuchereria bancrofti ''Wuchereria bancrofti'' is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis. It is one of the three parasitic worms, together with ''Brugia malayi'' and '' B. timori'', that infect the lymphati ...
'', Japanese encephalitis,
chikungunya Chikungunya is an infection caused by the chikungunya virus (CHIKV). The disease was first identified in 1952 in Tanzania and named based on the Kimakonde words for "to become contorted". Chikungunya has become a global health concern due to ...
and filariasis in Africa and Asia; and Murray Valley encephalitis and Ross River fever in Australia.
Vertical transmission Vertical transmission of symbionts is the transfer of a microbial symbiont from the parent directly to the offspring.  Many metazoan species carry symbiotic bacteria which play a mutualistic, commensal, or parasitic role.  A symbiont is acq ...
from adult mosquitos to larvae is possible. Depending on the situation, source reduction, biocontrol, larviciding (killing of
larva A larva (; : larvae ) is a distinct juvenile form many animals undergo before metamorphosis into their next life stage. Animals with indirect development such as insects, some arachnids, amphibians, or cnidarians typically have a larval phase ...
e), or adulticiding (killing of adults) may be used to manage mosquito populations. These techniques are accomplished using habitat modification,
pesticide Pesticides are substances that are used to control pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for approximately 50% of all p ...
, biological-control agents, and trapping. The advantage of non-toxic methods of control is they can be used in
Conservation Area Protected areas or conservation areas are locations which receive protection because of their recognized natural or cultural values. Protected areas are those areas in which human presence or the exploitation of natural resources (e.g. firewoo ...
s.
Integrated pest management Integrated pest management (IPM), also known as integrated pest control (IPC) integrates both chemical and non-chemical practices for economic control of pests. The UN's Food and Agriculture Organization defines IPM as "the careful consideratio ...
(IPM) is the use of the most environmentally appropriate method or combination of methods to control pest populations. Typical mosquito-control programs using IPM first conduct surveys, in order to determine the
species composition Relative species abundance is a component of biodiversity and is a measure of how common or rare a species is relative to other species in a defined location or community.Hubbell, S. P. 2001. ''The unified neutral theory of biodiversity and biogeog ...
, relative abundance and seasonal distribution of adult and larval mosquitoes, and only then is a control strategy defined.


Monitoring mosquito populations

Adult mosquito populations may be monitored by landing rate counts, mechanical traps or by, lidar technology. For landing rate counts, an inspector visits a set number of sites every day, counting the number of adult female mosquitoes that land on a part of the body, such as an arm or both legs, within a given time interval. Mechanical traps use a fan to blow adult mosquitoes into a collection bag that is taken back to the laboratory for analysis of catch. The mechanical traps use visual cues (light, black/white contrasts) or chemical attractants that are normally given off by mosquito hosts (e.g.,
carbon dioxide Carbon dioxide is a chemical compound with the chemical formula . It is made up of molecules that each have one carbon atom covalent bond, covalently double bonded to two oxygen atoms. It is found in a gas state at room temperature and at norma ...
,
ammonia Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the chemical formula, formula . A Binary compounds of hydrogen, stable binary hydride and the simplest pnictogen hydride, ammonia is a colourless gas with a distinctive pu ...
,
lactic acid Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as wel ...
, octenol) to attract adult female mosquitoes. These cues are often used in combination. Entomology lidar detection has the possibility of showing the difference between male and female mosquitoes. Monitoring larval mosquito populations involves collecting larvae from standing water with a dipper or a turkey baster. The habitat, approximate total number of larvae and pupae, and species are noted for each collection. An alternative method works by providing artificial breeding spots ( ovitraps) and collecting and counting the developing larvae at fixed intervals. Monitoring these mosquito populations is crucial to see what species are present, if mosquito numbers are rising or falling, and detecting any diseases they carry. Mosquito Alert is a cooperative
citizen science The term citizen science (synonymous to terms like community science, crowd science, crowd-sourced science, civic science, participatory monitoring, or volunteer monitoring) is research conducted with participation from the general public, or am ...
project, currently run as a
non-profit A nonprofit organization (NPO), also known as a nonbusiness entity, nonprofit institution, not-for-profit organization, or simply a nonprofit, is a non-governmental (private) legal entity organized and operated for a collective, public, or so ...
and coordinated by four public research centers in Spain. The aim of the project is to study, monitor, and fight the spread of invasive mosquitos. The project provided the first detection of the Asian bush mosquito '' Aedes japonicus'' in Spain in 2018, providing the first report of a population of mosquitos that were located 1,300 km from their previously nearest known location in Europe.


Climate change and mosquito habitats

Climate change has enabled mosquitoes such as ''
Aedes aegypti ''Aedes aegypti'' ( or from Greek 'hateful' and from Latin, meaning 'of Egypt'), sometimes called the Egyptian mosquito, dengue mosquito or yellow fever mosquito, is a mosquito that spreads diseases like dengue fever, yellow fever, malar ...
'' and ''
Aedes albopictus ''Aedes albopictus'' (synonym (taxonomy), synonym ''Stegomyia albopicta''), from the mosquito (Culicidae) family (biology), family, also known as the (Asian) tiger mosquito or forest mosquito, is a mosquito native to the tropical and Subtropics ...
'' to spread into new geographic regions, including temperate areas where they were previously unable to survive. Warmer temperatures accelerate mosquito development, shorten breeding cycles, and increase biting frequency, all of which enhance the potential for disease transmission. Shifts in rainfall patterns and the increased frequency of extreme weather events also create more stagnant water sources, which are ideal breeding grounds for mosquitoes. These ecological changes have contributed to the emergence or resurgence of mosquito-borne diseases such as dengue, Zika, and
chikungunya Chikungunya is an infection caused by the chikungunya virus (CHIKV). The disease was first identified in 1952 in Tanzania and named based on the Kimakonde words for "to become contorted". Chikungunya has become a global health concern due to ...
in parts of Europe and North America. In response, public health organizations have begun integrating climate-based data,
remote sensing Remote sensing is the acquisition of information about an physical object, object or phenomenon without making physical contact with the object, in contrast to in situ or on-site observation. The term is applied especially to acquiring inform ...
, and
predictive modeling Predictive modelling uses statistics to predict outcomes. Most often the event one wants to predict is in the future, but predictive modelling can be applied to any type of unknown event, regardless of when it occurred. For example, predictive mod ...
into their surveillance systems to monitor habitat suitability and guide early warning efforts for mosquito population surges. Understanding the relationship between climate variables and mosquito ecology is now considered a key component of proactive vector control strategies.


Community-based habitat reduction


2010 study in New Jersey
evaluated how community participation can improve mosquito control through source reduction.
AmeriCorps AmeriCorps ( ; officially the Corporation for National and Community Service or CNCS) is an Independent agencies of the United States government, independent agency of the United States government that engages more than five million Americans in ...
volunteers were trained to identify and explain mosquito breeding sites such as planters, rain barrels, and discarded containers. These peer educators visited over 750 homes, offering active, on-site education. Compared to control areas, the communities that received active outreach saw a 22.6% decrease in unmanaged container habitats. Additional events like tire disposal and trash can modification days encouraged long-term engagement. The study found that community-driven efforts led to measurable behavior change, particularly when residents had hands-on involvement.


AI-enabled mosquito surveillance

Recent research has explored the use of robotics and
artificial intelligence Artificial intelligence (AI) is the capability of computer, computational systems to perform tasks typically associated with human intelligence, such as learning, reasoning, problem-solving, perception, and decision-making. It is a field of re ...
to improve mosquito surveillance. Th
"Dragonfly" robot
developed in Singapore, uses a deep learning algorithm called YOLO V4 (You Only Look Once version 4) to detect and classify mosquitoes. It can identify ''
Aedes aegypti ''Aedes aegypti'' ( or from Greek 'hateful' and from Latin, meaning 'of Egypt'), sometimes called the Egyptian mosquito, dengue mosquito or yellow fever mosquito, is a mosquito that spreads diseases like dengue fever, yellow fever, malar ...
'', ''
Aedes albopictus ''Aedes albopictus'' (synonym (taxonomy), synonym ''Stegomyia albopicta''), from the mosquito (Culicidae) family (biology), family, also known as the (Asian) tiger mosquito or forest mosquito, is a mosquito native to the tropical and Subtropics ...
'', and ''
Culex ''Culex'' or typical mosquitoes are a genus of mosquitoes, several species of which serve as vectors of one or more important diseases of birds, humans, and other animals. The diseases they vector include arbovirus infections such as West Nil ...
'' species from glue traps with an accuracy of up to 88% in offline tests and 82% in real-time field trials. The robot maps mosquito detections on a two-dimensional grid, helping researchers visualize population hotspots. This automated approach reduces the need for manual identification and supports faster response times in high-risk areas.


Mechanical control

Mechanical control is the management and control using physical means.


Source reduction

Since many mosquitoes breed in
standing water Water stagnation occurs when water stops Environmental flow, flowing for a long period of time. Stagnant water can be a significant environmental hazard. Dangers Malaria and dengue are among the main dangers of still water, which can become ...
, source reduction can be as simple as emptying water from containers around the home. This is something that homeowners can accomplish. Mosquito breeding grounds can be eliminated at home by removing unused plastic pools, old
tire A tire (North American English) or tyre (Commonwealth English) is a ring-shaped component that surrounds a Rim (wheel), wheel's rim to transfer a vehicle's load from the axle through the wheel to the ground and to provide Traction (engineeri ...
s, or
bucket A bucket is typically a watertight, vertical Cylinder (geometry), cylinder or Truncation (geometry), truncated Cone (geometry), cone or square, with an open top and a flat bottom that is attached to a semicircular carrying handle (grip), handle ...
s; by clearing clogged gutters and repairing leaks around
faucet A tap (also spigot or faucet: see usage variations) is a valve controlling the release of a fluid. Nomenclature United Kingdom * Tap is used in the United Kingdom and most of the Commonwealth for any everyday type of valve, particularly ...
s; by regularly (at most every 4 days) changing water in
bird bath A bird bath (or birdbath) is an artificial puddle or small shallow pond, created with a water-filled basin, in which birds may drink, bathe, and cool themselves. A bird bath can be a garden ornament, small reflecting pool, outdoor sculpture, and ...
s; and by filling or draining puddles, swampy areas, and tree stumps. Eliminating such mosquito breeding areas can be an extremely effective and permanent way to reduce mosquito populations without resorting to insecticides. However, this may not be possible in parts of the
developing world A developing country is a sovereign state with a less-developed industrial base and a lower Human Development Index (HDI) relative to developed countries. However, this definition is not universally agreed upon. There is also no clear agreeme ...
where water cannot be readily replaced due to irregular water supply. Many individuals also believe mosquito control is the government's responsibility, so if these methods are not done regularly by homeowners then the effectiveness is reduced. Open water marsh management (OWMM) involves the use of shallow ditches, to create a network of water flow within marshes and to connect the marsh to a pond or canal. The network of ditches drains the mosquito habitat and lets in fish which will feed on mosquito larvae. This reduces the need for other control methods such as
pesticide Pesticides are substances that are used to control pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for approximately 50% of all p ...
s. Simply giving the predators access to the mosquito larvae can result in long-term mosquito control. Open-water marsh management is used on both the eastern and western coasts of the United States. Rotational impoundment management (RIM) involves the use of large pumps and culverts with gates to control the water level within an impounded marsh. RIM allows mosquito control to occur while still permitting the marsh to function in a state as close to its natural condition as possible. Water is pumped into the marsh in the late spring and summer to prevent the female mosquito from laying her eggs on the soil. The marsh is allowed to drain in the fall, winter, and early spring. Gates in the culverts are used to permit fish, crustaceans, and other marsh organisms to enter and exit the marsh. RIM allows the mosquito-control goals to be met while at the same time reducing the need for pesticide use within the marsh. Rotational impoundment management is used to a great extent on the east coast of Florida. A 2019 study also explored the idea of using
unmanned aerial vehicle An unmanned aerial vehicle (UAV) or unmanned aircraft system (UAS), commonly known as a drone, is an aircraft with no human pilot, crew, or passengers onboard, but rather is controlled remotely or is autonomous.De Gruyter Handbook of Dron ...
s as a valid strategy to identify and prioritize water bodies where
disease vectors In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen such as a parasite or microbe, to another living organism. Agents regarded as vectors are mostly blood-sucking ( hematophagous) arthropods such ...
such as ''Ny''. ''darlingi'' are most likely to breed.


Oil drip

An oil drip can or oil drip barrel was a common and nontoxic anti-mosquito measure. The thin layer of oil on top of the water prevents mosquito breeding in two ways: mosquito larvae in the water cannot penetrate the oil film with their breathing tube, and so drown and die; also adult mosquitoes do not lay eggs on the oiled water.


Mosquito traps

A traditional approach to controlling mosquito populations is the use of ovitraps or lethal ovitraps, which provide artificial breeding spots for mosquitoes to lay their eggs. While ovitraps only trap eggs, lethal ovitraps usually contain a chemical inside the trap that is used to kill the adult mosquito and/or the larvae in the trap. Studies have shown that with enough of these lethal ovitraps, ''Aedes'' mosquito populations can be controlled. A recent approach is the automatic lethal ovitrap, which works like a traditional ovitrap but automates all steps needed to provide the breeding spots and to destroy the developing larvae. In 2016 researchers from
Laurentian University Laurentian University (), officially Laurentian University of Sudbury, is a mid-sized Bilingualism in Canada, bilingual public university in Greater Sudbury, Ontario, Canada, incorporated on March 28, 1960. Laurentian offers a variety of undergr ...
released a design for a low cost trap called an Ovillanta which consists of attractant-laced water in a section of discarded rubber tire. At regular intervals the water is run through a filter to remove any deposited eggs and larva. The water, which then contains an 'oviposition' pheromone deposited during egg-laying, is reused to attract more mosquitoes. Two studies have shown that this type of trap can attract about seven times as many mosquito eggs as a conventional ovitrap. Some newer mosquito traps or known mosquito attractants emit a plume of carbon dioxide together with other mosquito attractants such as sugary scents,
lactic acid Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as wel ...
, octenol, warmth, water vapor and sounds. By mimicking a mammal's scent and outputs, the trap draws female mosquitoes toward it, where they are typically sucked into a net or holder by an electric fan where they are collected. According to the American Mosquito Control Association, the trap will kill some mosquitoes, but their effectiveness in any particular case will depend on a number of factors such as the size and species of the mosquito population and the type and location of the breeding habitat. They are useful in specimen collection studies to determine the types of mosquitoes prevalent in an area but are typically far too inefficient to be useful in reducing mosquito populations.


Trap larva

This is a process of achieving sustainable mosquito control in an eco friendly manner by providing artificial breeding grounds with an ovitrap or an ovillanta utilizing common household utensils and destroying larvae by non-hazardous natural means such as throwing them in dry places or feeding them to larvae eating fishes like ''Gambusia affinis'', or suffocating them by spreading a thin plastic sheet over the entire water surface to block atmospheric air. Shifting the water with larvae to another vessel and pouring a few drops of
kerosene Kerosene, or paraffin, is a combustibility, combustible hydrocarbon liquid which is derived from petroleum. It is widely used as a fuel in Aviation fuel, aviation as well as households. Its name derives from the Greek (''kērós'') meaning " ...
oil or insecticide/larvicide in it is another option for killing wrigglers, but ''not preferred due to its environmental impact''. Most of the ornamental fishes eat mosquito larvae.


Chemical control

Chemical control is the management and control using chemical means.


Larviciding

Control of larvae can be accomplished through use of contact poisons, growth regulators, surface films, stomach poisons (including bacterial agents), and biological agents such as fungi, nematodes, copepods, and fish. A chemical commonly used in the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
is methoprene, considered slightly
toxic Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a subst ...
to larger animals, which mimics and interferes with natural growth hormones in mosquito larvae, preventing development. Methoprene is frequently distributed in time-release
briquette A briquette (; also spelled briquet) is a compressed block of coal dust or other combustible biomass material (e.g. charcoal, sawdust, wood chips, peat, or paper) used for fuel and kindling to start a combustion, fire. The term is a diminutive der ...
form in breeding areas. Another chemical is Temefos or temephos, a sand granular insecticide is used to treat water infected with disease carrying insects. It is believed by some researchers that the larvae of ''
Anopheles gambiae The ''Anopheles gambiae'' complex consists of at least seven morphologically indistinguishable species of mosquitoes in the genus ''Anopheles''. The complex was recognised in the 1960s and includes the most important vectors of malaria in sub- ...
'' (important vectors of malaria) can survive for several days on moist mud, and that treatments should therefore include mud and soil several meters from puddles.


Adulticiding

Control of adult mosquitoes is the most familiar aspect of mosquito control to most of the public. It is accomplished by ground-based applications or via
aerial application Aerial application, or crop dusting, involves spraying crops with crop protection products from an agricultural aircraft. Planting certain types of seed are also included in aerial application. The specific spreading of fertilizer is also known a ...
of residual chemical insecticides such as
Duet A duet (italian language, Italian: ''duo'') is a musical composition for two Performing arts, performers in which the performers have equal importance to the piece, often a composition involving two singers or two pianists. It differs from a har ...
. Generally modern mosquito-control programs in developed countries use low-volume applications of insecticides, although some programs may still use thermal fogging. Beside fogging there are some other
insect repellent An insect repellent (also commonly called "bug spray" or "bug deterrent") is a substance applied to the skin, clothing, or other surfaces to discourage insects (and arthropods in general) from landing or climbing on that surface. Insect repellent ...
s for indoors and outdoors. An example of a synthetic insect repellent is
DEET ''N'',''N''-Diethyl-''meta''-toluamide, also called diethyltoluamide or DEET (, from DET, the initials of di- + ethyl + toluamide), is the oldest, one of the most effective, and most common active ingredients in commercial insect repellents. ...
. A naturally occurring repellent is citronella. Indoor Residual Spraying (
IRS The Internal Revenue Service (IRS) is the revenue service for the Federal government of the United States, United States federal government, which is responsible for collecting Taxation in the United States, U.S. federal taxes and administerin ...
) is another method of adulticide. Walls of properties are sprayed with an insecticide, the mosquitoes die when they land on the surface covered in insecticide. To control adult mosquitoes in India, van mounted fogging machines and hand fogging machines are used. File:Anti-mosquito fogging operation.jpg, Anti-mosquito fogging operation in
India India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since ...
File:Mosquito repellent 1.jpg, A mosquito repellent vaporizer containing Prallethrin File:Mosquito coil.JPG, A
mosquito coil A mosquito coil is a Insect repellent, mosquito-repelling incense, usually made into a spiral, and typically made using dried paste of pyrethrum powder. The coil is usually held at the center of the spiral, suspending it in the air, or wedged by ...
File:House IRS Kenya 7 (36006012186).jpg, Indoor residual spraying in Kenya File:Mosquitoes-Killedy-By-DDT-Lake-Victoria.JPG, Walls on
IRS The Internal Revenue Service (IRS) is the revenue service for the Federal government of the United States, United States federal government, which is responsible for collecting Taxation in the United States, U.S. federal taxes and administerin ...
-treated bathroom on the shores of Lake Victoria. The mosquitoes remain on the wall until they fall down dead on the floor. File:DDT spray 1958.jpg, In 1958, the
National Malaria Eradication Program In the United States, the National Malaria Eradication Program (NMEP) was launched in July 1947. By 1951 this federal program—with state and local participation—had reduced the incidence of malaria in the United States to the point that the pr ...
implemented the wide-scale use of DDT for mosquito control.


Use of DDT

DDT was formerly used throughout the world for large area mosquito control, but it is now banned in most developed countries. Controversially, DDT remains in common use in many
developing countries A developing country is a sovereign state with a less-developed Secondary sector of the economy, industrial base and a lower Human Development Index (HDI) relative to developed countries. However, this definition is not universally agreed upon. ...
(14 countries were reported to be using it in 2009Cone, Maria (4 May 2009
Should DDT Be Used to Combat Malaria?
Scientific American. Retrieved 13 October 2014
), which claim that the public-health cost of switching to other control methods would exceed the harm caused by using DDT. It is sometimes approved for use only in specific, limited circumstances where it is most effective, such as application to walls. The role of DDT in combating mosquitoes has been the subject of considerable controversy. Although DDT has been proven to affect biodiversity and cause eggshell thinning in birds such as the bald eagle, some say that DDT is the most effective weapon in combating mosquitoes, and hence malaria. While some of this disagreement is based on differences in the extent to which disease control is valued as opposed to the value of biodiversity, there is also genuine disagreement amongst experts about the costs and benefits of using DDT. Notwithstanding, DDT-resistant mosquitoes have started to increase in numbers, especially in tropics due to mutations, reducing the effectiveness of this chemical; these mutations can rapidly spread over vast areas if pesticides are applied indiscriminately (Chevillon et al. 1999). In areas where DDT resistance is encountered, malathion,
propoxur Propoxur (Baygon) is a carbamate non-systemic insecticide, produced from catechol, and was introduced in 1959. It has a fast knockdown and long residual effect, and is used against turf, forestry, and household pests and fleas. It is also used in ...
or lindane is used.


Chemicals from body odor that attract mosquitoes

Mosquitoes Mosquitoes, the Culicidae, are a family of small flies consisting of 3,600 species. The word ''mosquito'' (formed by '' mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mosquitoes have a slender segmented body, ...
are highly adept at locating their human hosts, largely due to their ability to detect specific chemicals present in human body odor. Research has identified several compounds in human sweat and skin that are particularly attractive to mosquitoes. Understanding these attractants is crucial for developing more effective mosquito control methods, including targeted repellents and traps that mimic human odors to lure mosquitoes away from people.


Key Attractants

# Carbon Dioxide (CO2): One of the most well-known attractants, carbon dioxide is exhaled by humans and detected by mosquitoes from a considerable distance. It is often the initial cue that mosquitoes use to locate potential hosts. #
Lactic Acid Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as wel ...
: Found in human sweat, lactic acid is a significant attractant for many mosquito species, including those that transmit malaria and dengue fever. Its concentration can vary among individuals, partly explaining why mosquitoes are more attracted to some people than others. # Octenol: Also known as mushroom alcohol, octenol is present in human breath and sweat. It is particularly attractive to some mosquito species and is used in combination with carbon dioxide in mosquito traps. # Acetone and Sulcatone: These compounds are found in human breath and skin, and research has shown that they also play a role in attracting mosquitoes. #
Ammonia Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the chemical formula, formula . A Binary compounds of hydrogen, stable binary hydride and the simplest pnictogen hydride, ammonia is a colourless gas with a distinctive pu ...
: Released through the skin, especially with increased sweat production, ammonia is another compound that attracts mosquitoes. Moreover, recent studies have implicated other compounds such as fatty acids and certain volatile organic compounds (VOCs) in mosquito attraction, expanding the list of known attractants. Among these attractants, CO2 and lactic acid are considered the most effective, with CO2 attracting mosquitoes from the longest distances and lactic acid influencing their preference for certain individuals.


Implications for Mosquito Control

Understanding the specific chemicals that attract mosquitoes facilitates the development of innovative control strategies. For example, mosquito traps that emit both CO2 and lactic acid have proven more effective in luring mosquitoes away from human populations, significantly reducing the risk of bites and the spread of diseases. Additionally, personal repellents engineered to mask or chemically alter these attractants can render individuals less detectable to mosquitoes. Integrating these repellents into daily personal care routines, especially in regions prone to mosquito-borne diseases, offers a proactive approach to disease prevention. Research into the chemical properties of human body odor that attract mosquitoes reveals complex interactions between mosquito host-seeking behavior and human chemical signatures. By deciphering these mechanisms, scientists aim to devise solutions that could substantially reduce the incidence of mosquito-borne diseases. Advances in synthetic biology and nanotechnology are opening new avenues for creating targeted compounds and delivery systems that efficiently combat mosquitoes without harming the environment.


Enhancements and Future Directions

While existing repellents and traps offer temporary solutions, they frequently fall short due to their limited duration of effectiveness and inconsistent efficacy across different mosquito species. For example, many current repellents do not provide all-night protection, and traps might not attract all types of mosquitoes. Future research should prioritize the discovery of new attractant compounds through molecular biology and high-throughput screening methods, aiming to develop more universally effective and durable mosquito control solutions. Addressing the ecological impacts of widespread use of chemical attractants and repellents is also essential. Careful evaluation is needed to ensure these methods do not harm non-target species or disrupt ecological balances. In practical scenarios, leveraging these insights could transform how we manage mosquito populations and reduce disease transmission. With ongoing technological advancements and deeper understanding of mosquito ecology, we can anticipate the development of next-generation repellents and attractant-based traps that provide robust and environmentally friendly protection against mosquitoes.


Biological control

Biological control Biological control or biocontrol is a method of controlling pests, whether pest animals such as insects and mites, weeds, or pathogens affecting animals or plants by using other organisms. It relies on predation, parasitism, herbivory, or o ...
is the management and control using biological means.


Natural predation

Biological pest control Biological control or biocontrol is a method of controlling pests, whether pest animals such as insects and mites, weeds, or pathogens affecting animals or plants by using other organisms. It relies on predation, parasitism, herbivory, or ot ...
, or "biocontrol", is the use of the natural enemies of pests like mosquitoes to manage the pest's populations. There are several types of biocontrol, including the direct introduction of parasites, pathogens, and predators to target mosquitoes. Effective biocontrol agents include predatory fish that feed on mosquito larvae such as mosquitofish (''Gambusia affinis'') and some
cyprinid Cyprinidae is a Family (biology), family of freshwater fish commonly called the carp or minnow family, including the carps, the true minnows, and their relatives the barb (fish), barbs and barbel (fish), barbels, among others. Cyprinidae is the ...
s (carps and minnows) and killifish. Tilapia also consume
mosquito Mosquitoes, the Culicidae, are a Family (biology), family of small Diptera, flies consisting of 3,600 species. The word ''mosquito'' (formed by ''Musca (fly), mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mos ...
larvae. Direct introduction of tilapia and mosquitofish into ecosystems around the world have had disastrous consequences. However, utilizing a controlled system via
aquaponics Aquaponics is a food production system that couples aquaculture (raising aquatic animals such as fish, crayfish, snails or prawns in tanks) with hydroponics (cultivating plants in water) whereby the nutrient-rich aquaculture water is fed to h ...
provides the mosquito control without the adverse effects to the ecosystem. Other predators include dragonfly (fly)
naiads In Greek mythology, the naiads (; ), sometimes also hydriads, are a type of female spirit, or nymph, presiding over fountains, wells, springs, streams, brooks and other bodies of fresh water. They are distinct from river gods, who embodied ...
, which consume mosquito larvae in the breeding waters, adult
dragonflies A dragonfly is a flying insect belonging to the infraorder Anisoptera below the order Odonata. About 3,000 extant species of dragonflies are known. Most are tropical, with fewer species in temperate regions. Loss of wetland habitat threate ...
, which eat adult mosquitoes, and some species of
lizard Lizard is the common name used for all Squamata, squamate reptiles other than snakes (and to a lesser extent amphisbaenians), encompassing over 7,000 species, ranging across all continents except Antarctica, as well as most Island#Oceanic isla ...
and
gecko Geckos are small, mostly carnivorous lizards that have a wide distribution, found on every continent except Antarctica. Belonging to the infraorder Gekkota, geckos are found in warm climates. They range from . Geckos are unique among lizards ...
. Biocontrol agents that have had lesser degrees of success include the predator mosquito '' Toxorhynchites'' and predator
crustaceans Crustaceans (from Latin meaning: "those with shells" or "crusted ones") are invertebrate animals that constitute one group of Arthropod, arthropods that are traditionally a part of the subphylum Crustacea (), a large, diverse group of mainly aquat ...
Mesocyclops copepods,
nematodes The nematodes ( or ; ; ), roundworms or eelworms constitute the phylum Nematoda. Species in the phylum inhabit a broad range of environments. Most species are free-living, feeding on microorganisms, but many are parasitic. Parasitic worms (he ...
and
fungi A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and mold (fungus), molds, as well as the more familiar mushrooms. These organisms are classified as one ...
. Predators such as birds, bats, lizards, and frogs have been used, but their effectiveness is only anecdotal.


Biocides

Instead of chemical insecticides, some researchers are studying biocides. Like all animals, mosquitoes are subject to disease. Invertebrate pathologists study these diseases in the hope that some of them can be utilized for mosquito management. Microbial pathogens of mosquitoes include viruses, bacteria, fungi, protozoa, nematodes and microsporidia. Most notably, scientists in
Burkina Faso Burkina Faso is a landlocked country in West Africa, bordered by Mali to the northwest, Niger to the northeast, Benin to the southeast, Togo and Ghana to the south, and Ivory Coast to the southwest. It covers an area of 274,223 km2 (105,87 ...
were studying the ''Metarhizium'' fungal species. This fungus in a high concentration can slowly kill mosquitoes. To increase the lethality of the fungus, a gene from a spider was inserted into the fungus causing it to produce a
neurotoxin Neurotoxins are toxins that are destructive to nervous tissue, nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insult (medical), insultsSpencer 2000 that can adversely affect function ...
. The gene was regulated to only activate when in mosquito hemolymph. Research was done to show the fungi would not affect other insects or humans. Two other species of fungi that can kill adult mosquitoes are ''
Metarhizium anisopliae ''Metarhizium anisopliae'' is a fungus, the type species in the ''Metarhizium'' genus. It grows naturally in soils throughout the world and causes disease in various insects by acting as a parasitoid. Ilya Ilyich Mechnikov, Ilya I. Mechnikov nam ...
'' and '' Beauveria bassiana''. Dead spores of the
soil Soil, also commonly referred to as earth, is a mixture of organic matter, minerals, gases, water, and organisms that together support the life of plants and soil organisms. Some scientific definitions distinguish dirt from ''soil'' by re ...
bacterium Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the ...
'' Bacillus thuringiensis'', especially '' Bt israelensis'' (BTI) interfere with dipteran larval digestive systems. It can be dispersed by hand or dropped by
helicopter A helicopter is a type of rotorcraft in which Lift (force), lift and thrust are supplied by horizontally spinning Helicopter rotor, rotors. This allows the helicopter to VTOL, take off and land vertically, to hover (helicopter), hover, and ...
in large areas. BTI loses effectiveness after the larvae turn into pupae, because they stop eating. BTI was reported to be widely applied in West Africa with limited adverse effects, and may pose lesser risk than chemical pesticides.


Wolbachia method

In the ''
Wolbachia ''Wolbachia'' is a genus of gram-negative bacteria infecting many species of arthropods and filarial nematodes. The symbiotic relationship ranges from parasitism to obligate mutualism. It is one of the most common parasitic microbes of arthrop ...
'' method, both male and female mosquitos that carry the ''Wolbachia'' bacterium are released into natural populations. ''Wolbachia'' boosts the natural immune response of the mosquito so that it does not easily get infected and become a host vector for mosquito-borne diseases. Therefore it is unable to easily transmit those viruses to people. This is known as replacement strategy as it aims to replace the natural population with ''Wolbachia''-carrying ones. Since 2011, the World Mosquito Program has conducted several trials and projects, in 14 countries across Asia, Latin America and Oceania.


Incompatible Insect Technique (IIT)

This approach also uses ''Wolbachia'' but involves the release of only male mosquitos that carry the ''Wolbachia'' bacterium. When these male mosquitos mate with wild female mosquitos, her eggs do not hatch due to lack of biocompatibility. ''Wolbachia'' is not endemic to wild mosquito populations although it is endemic in 50% of all insect species. This is known as suppression strategy as it aims to suppress the natural reproduction cycle. ''Wolbachia-Aedes'' suppression has been piloted in various countries such as Myanmar (1967), French Polynesia (2009, 2012), USA (2014-2016, 2018), Thailand (2016), Australia (2017), Singapore (since 2016) and Puerto Rico (2020).


Projects

Maui and Kuai, Hawaii - A series of IIT projects were planned to protect endangered bird species from avian malaria. The projects involve the release of large numbers of male mosquitos infected with a strain of ''Wolbachia'' that is incompatible with the strain carried by resident females. These mosquitos would not be irradiated or subject to genetic modification.


Sterile Insect Technique (SIT)

Introducing large numbers of sterile males is another approach to reducing mosquito numbers. This is called
Sterile Insect Technique The sterile insect technique (SIT) is a method of biological pest control, biological insect control, whereby overwhelming numbers of infertility, sterile insects are released into the wild. The released insects are preferably male, as this is mo ...
(SIT). Radiation is used to disrupt DNA in the mosquitoes and randomly create mutations. Males with mutations that disrupt their fertility are selected and released in mass into the wild population. These sterile males mate with wild type females and no offspring is produced, reducing the population size.


Projects

Guangzhou, China - A combination of SIT with IIT, were used in a mosquito control program in Guangzhou, China. The pilot trial was carried out with the support of the
IAEA The International Atomic Energy Agency (IAEA) is an intergovernmental organization that seeks to promote the peaceful use of nuclear energy and to inhibit its use for any military purpose, including nuclear weapons. It was established in 1957 ...
in cooperation with the
Food and Agriculture Organization The Food and Agriculture Organization of the United Nations; . (FAO) is a specialized agency of the United Nations that leads international efforts to defeat hunger and improve nutrition and food security. Its Latin motto, , translates ...
of the
United Nations The United Nations (UN) is the Earth, global intergovernmental organization established by the signing of the Charter of the United Nations, UN Charter on 26 June 1945 with the stated purpose of maintaining international peace and internationa ...
(FAO). The pilot demonstrated the successful near-elimination of field populations of the world's most invasive mosquito species, ''
Aedes albopictus ''Aedes albopictus'' (synonym (taxonomy), synonym ''Stegomyia albopicta''), from the mosquito (Culicidae) family (biology), family, also known as the (Asian) tiger mosquito or forest mosquito, is a mosquito native to the tropical and Subtropics ...
'' (Asian tiger mosquito). The two-year trial (2016–2017) covered a 32.5-hectare area on two relatively isolated islands in the Pearl River in Guangzhou. It involved the release of about 200 million irradiated mass-reared adult male mosquitoes exposed to ''Wolbachia'' bacteria.


Genetic modification

These techniques share the characteristic of introducing lethal genes and reducing the size of the mosquito population over time.


Growth inhibition

Another control approach under investigation for ''
Aedes aegypti ''Aedes aegypti'' ( or from Greek 'hateful' and from Latin, meaning 'of Egypt'), sometimes called the Egyptian mosquito, dengue mosquito or yellow fever mosquito, is a mosquito that spreads diseases like dengue fever, yellow fever, malar ...
'' uses a strain that is genetically modified to require the antibiotic tetracycline to develop beyond the larval stage. Modified males develop normally in a nursery while they are supplied with this chemical and can be released into the wild. However, their subsequent offspring will lack tetracycline in the wild and never mature. Field trials were conducted in the Cayman Islands, Malaysia and Brazil to control the mosquitoes that cause dengue fever. In April 2014, Brazil's National Technical Commission for Biosecurity approved the commercial release of the modified mosquito. The FDA is the lead agency for regulating genetically-engineered mosquitoes in the United States. In 2014 and 2018 research was reported into other genetic methods including cytoplasmic incompatibility, chromosomal translocations, sex distortion and gene replacement. Although several years away from the field trial stage, if successful these other methods have the potential to be cheaper and to eradicate the ''Aedes aegypti'' mosquito more efficiently. A pioneering experimental demonstration of the gene drive method eradicated small populations of ''
Anopheles gambiae The ''Anopheles gambiae'' complex consists of at least seven morphologically indistinguishable species of mosquitoes in the genus ''Anopheles''. The complex was recognised in the 1960s and includes the most important vectors of malaria in sub- ...
.'' In 2020, Oxitec's non-biting Friendly Aedes aegypti mosquito was approved for release by the US EPA and Florida state authorities.


Projects

Malaysia - In several experiments, researchers released batches of male adult Aedes mosquitos with genetic modifications to study the effects of dispersal and reproduction in natural populations. Mosquito traps were ultilized for the purpose of these studies. The process allowed for the opportunity to determine which mosquitoes were affected, and provided a group to be re-released with genetic modifications resulting in the OX513A variant to reduce reproduction. Adult mosquitoes are attracted inside the traps where they died of dehydration.


Factor EOF1

Research is being conducted that indicates that dismantling a protein associated with eggshell organization, factor EOF1 (factor 1), which may be unique to mosquitoes, may be a means to hamper their reproduction effectively in the wild without creating a resistant population or affecting other animals.


Legal measures

In
Singapore Singapore, officially the Republic of Singapore, is an island country and city-state in Southeast Asia. The country's territory comprises one main island, 63 satellite islands and islets, and one outlying islet. It is about one degree ...
, under the Control of Vectors and Pesticides Act there is a legal duty on occupants to prevent ''Aedes'' mosquitos from breeding in their homes. If breeding mosquitos are found by inspectors, occupiers are subject to a fine of 5,000
Singapore dollar The Singapore dollar (currency sign, sign: S$; ISO 4217, code: SGD) is the official currency of the Singapore, Republic of Singapore. It is divided into 100 cent (currency), cents (, , ). It is normally abbreviated with the dollar sign $, or ...
s or imprisonment for a term not exceeding 3 months or both.


Proposals to eradicate mosquitoes

Some biologists have proposed the deliberate extinction of certain mosquito species. Biologist Olivia Judson has advocated " specicide" of thirty
mosquito Mosquitoes, the Culicidae, are a Family (biology), family of small Diptera, flies consisting of 3,600 species. The word ''mosquito'' (formed by ''Musca (fly), mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mos ...
species by introducing a genetic element which can insert itself into another crucial gene, to create
recessive In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and ...
" knockout genes". She says that the ''
Anopheles ''Anopheles'' () is a genus of mosquito first described by the German entomologist Johann Wilhelm Meigen, J. W. Meigen in 1818, and are known as nail mosquitoes and marsh mosquitoes. Many such mosquitoes are Disease vector, vectors of the paras ...
'' mosquitoes (which spread
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
) and ''
Aedes ''Aedes'' (also known as the tiger mosquito) is a genus of mosquitoes originally found in tropical and subtropical zones, but now found on all continents except Antarctica. Some species have been spread by human activity: ''Aedes albopictus'', ...
'' mosquitoes (which spread
dengue fever Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. Asymptomatic infections are uncommon, mild cases happen frequently; if symptoms appear, they typically begin 3 to 14 days after i ...
, yellow fever,
elephantiasis Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling (edema). It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstru ...
, zika, and other diseases) represent only 30 out of some 3,500 mosquito species; eradicating these would save at least one million human lives per year, at a cost of reducing the
genetic diversity Genetic diversity is the total number of genetic characteristics in the genetic makeup of a species. It ranges widely, from the number of species to differences within species, and can be correlated to the span of survival for a species. It is d ...
of the
family Family (from ) is a Social group, group of people related either by consanguinity (by recognized birth) or Affinity (law), affinity (by marriage or other relationship). It forms the basis for social order. Ideally, families offer predictabili ...
Culicidae Mosquitoes, the Culicidae, are a Family (biology), family of small Diptera, flies consisting of 3,600 species. The word ''mosquito'' (formed by ''Musca (fly), mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mos ...
by 1%. She further argues that since species become extinct "all the time" the disappearance of a few more will not destroy the
ecosystem An ecosystem (or ecological system) is a system formed by Organism, organisms in interaction with their Biophysical environment, environment. The Biotic material, biotic and abiotic components are linked together through nutrient cycles and en ...
: "We're not left with a wasteland every time a species vanishes. Removing one species sometimes causes shifts in the populations of other species — but different need not mean worse." In addition, anti-malarial and mosquito control programs offer little realistic hope to the 300 million people in
developing nation A developing country is a sovereign state with a less-developed industrial base and a lower Human Development Index (HDI) relative to developed countries. However, this definition is not universally agreed upon. There is also no clear agreeme ...
s who will be infected with acute illnesses each year. Although trials are ongoing, she writes that if they fail: "We should consider the ultimate swatting." Biologist E. O. Wilson has advocated the extinction of several species of mosquito, including malaria vector ''
Anopheles gambiae The ''Anopheles gambiae'' complex consists of at least seven morphologically indistinguishable species of mosquitoes in the genus ''Anopheles''. The complex was recognised in the 1960s and includes the most important vectors of malaria in sub- ...
''. Wilson stated, "I'm talking about a very small number of species that have co-evolved with us and are preying on humans, so it would certainly be acceptable to remove them. I believe it's just common sense." Insect ecologist Steven Juliano has argued that "it's difficult to see what the downside would be to removal, except for collateral damage". Entomologist Joe Conlon stated that "If we eradicated them tomorrow, the ecosystems where they are active will hiccup and then get on with life. Something better or worse would take over." However, David Quammen has pointed out that mosquitoes protect forests from human exploitation and may act as competitors for other insects. In terms of malaria control, if populations of mosquitoes were temporarily reduced to zero in a region, then this would exterminate malaria, and the mosquito population could then be allowed to rebound.


See also

* Bug zapper *
Chikungunya Chikungunya is an infection caused by the chikungunya virus (CHIKV). The disease was first identified in 1952 in Tanzania and named based on the Kimakonde words for "to become contorted". Chikungunya has become a global health concern due to ...
* Fly-killing device * Flying syringe * Mosquito eater * Mosquito laser * Mosquito repellant * Proposed planned extinction of mosquito species *
Vector control Vector control is any method to limit or eradicate the mammals, birds, insects or other arthropods (here collectively called " vectors") which transmit disease pathogens. The most frequent type of vector control is mosquito control using a varie ...
*
West Nile virus West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever. It is a member of the family ''Flaviviridae'', from the genus ''Flavivirus'', which also contains the Zika virus, dengue virus, and yellow fever virus. The virus ...


Citations


General references

* * * * * * * Martinez, Julien et al. “Differential attraction in mosquito-human interactions and implications for disease control.” Philosophical transactions of the Royal Society of London. Series B, Biological sciences vol. 376,1818 (2021): 20190811. doi:10.1098/rstb.2019.0811 * Connelly, C Roxanne, and Jeff Borchert. “MOSQUITO CONTROL EMERGENCY PREPAREDNESS AND RESPONSE TO NATURAL DISASTERS.” Journal of the American Mosquito Control Association vol. 36,2 Suppl (2020): 2-4. doi:10.2987/8756- 971X-36.2S.2 * * Carlson, Douglas B et al. “Mosquito Control and Coastal Development: How they Have Coexisted and Matured in Florida and Australia.” Journal of the American Mosquito Control Association vol. 35,2 (2019): 123-134. doi:10.2987/18-6807.1 *


External links


CDC info page on malaria vector control


{{Authority control Culicidae Epidemiology Flies and humans Insect control Malaria