Mark Smith may refer to:

Academia

* Marc Smith (palaeographer) (born 1963), French palaeographer * Mark Smith (physicist), British physicist and Vice-Chancellor of Lancaster University * Mark A. Smith (1965–2010), professor of pathology at Case Western Reserve University * Mark M. Smith (active since 1997), American historian * Mark S. Smith (born 1956), American biblical scholar, professor at NYU

Arts and entertainment

Drama, television, and film

* Mark Smith (actor, born 1887) (1887–1944), American actor * Mark Smith (actor, born 1969) (born 1969), English bodybuilder and participant on the UK television show ''Gladiators'' * Mark Smith (sound engineer) (active since 1987), American sound engineer who won an Academy Award * Mark Coles Smith (born 1987), Australian actor * Mark L. Smith (born 1996), American director and screenwriter * Mark Landon Smith (born 1964), American playwright and actor

Literature

* Mark Smith (author), British author of fantasy game books * Mark Smith (journalist), American journalist * Mark Smith (novelist) (born 1935), American best-selling author * Mark Andrew Smith (born 1979), American comic book author * Mark Haskell Smith (born 1957), American writer

Music

*Mark Smith, member of post-rock band Explosions in the Sky (active since 1999) * Mark Smith (musician) (1960–2009), British bassist and record producer * Mark E. Smith (1957–2018), British singer and founder of The Fall * Mark Edgley Smith (1955–2008), British composer

Visual arts

* Mark T. Smith (born 1968), American painter

Politics

* Mark Smith (Iowa politician) (born 1952), American state representative * Mark Smith (South Carolina politician), American state representative-elect * Mark Smith (Canadian politician) (born 1960), Canadian politician for the Legislative Assembly of Alberta * Mark W. Smith (born 1968), American author, attorney, and political analyst * Marcus A. Smith (1851–1924), known as Mark, U.S. Senator from Arizona

Science and engineering

* Mark L. Smith (physician) (active since 1999), American physician and plastic surgeon * Mark Smith (R/C modeling pioneer) (born 1950), designer of radio-controlled model airplanes

Sports

* Mark Smith (American football) (born 1974), American football player * Mark Smith (American racing driver) (born 1967), American CART competitor * Mark Smith (athlete) (born 1971), English athlete * Mark Smith (basketball) (born 1999), American basketball player * Mark Smith (British racing driver) (born 1965), English BTCC competitor * Mark Smith (cricketer) (born 1975), Zimbabwean cricketer * Mark Smith (fencer) (born 1956), American Olympic fencer * Mark Smith (footballer, born 1960), English football player (Sheffield Wednesday) * Mark Smith (footballer, born October 1961), English football player (West Ham United) * Mark Smith (footballer, born December 1961), English football player and manager * Mark Smith (footballer, born 1964), Scottish football player (Stoke City) * Mark Smith (footballer, born 1973), English football player (Crewe Alexandra) * Mark Smith (ice hockey) (born 1977), Canadian professional ice hockey player * Mark Smith (outfielder) (born 1970), American former professional baseball player * Mark Smith (Pennsylvanian racing driver) (born 1971), racing driver from Pennsylvania * Mark Smith (pitcher) (born 1955), American former professional baseball player * Mark Smith (racing engineer) (born 1961), Formula One designer * Mark Smith (rugby league) (born 1981), English former rugby league player * Bison Smith (Mark Smith, 1973–2011), American professional wrestler *Mark Smith (high jumper), winner of the 1953 NCAA DI outdoor high jump championship

Other

* Mark C. Smith (1940–2007), founder and chief executive officer of ADTRAN * Mark E. Smith (Civil Air Patrol), National Commander of the Civil Air Patrol * Mark Alan Smith (born 1949), American serial killer *Mark Smith, creator of the train travel website The Man in Seat Sixty-One