Lys-MDMA, or lysine-MDMA, also known as ''N''-(L-lysinamidyl)-MDMA, is a

prodrug A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be ...

MDMA 3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (tablet form), and molly (crystal form), is an empathogen–entactogenic drug with stimulant and minor Psychedelic drug, psychedelic properties. In studies, it has been used ...

which is being investigated for possible use as a

pharmaceutical drug Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...

in the treatment of

psychiatric disorder A mental disorder, also referred to as a mental illness, a mental health condition, or a psychiatric disability, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. A mental disorder is ...

Structurally A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ...

, lys-MDMA is to MDMA as

lisdexamfetamine Lisdexamfetamine, sold under the brand names Vyvanse and Elvanse among others, is a stimulant medication that is used as a treatment for attention deficit hyperactivity disorder (ADHD) in children and adults and for moderate-to-severe binge ...

is to

dextroamphetamine Dextroamphetamine (international nonproprietary name, INN: dexamfetamine) is a potent central nervous system (CNS) stimulant and enantiomer of amphetamine that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narc ...

As of August 2024, a phase 1

clinical trial Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...

comparing MDMA, MDA, lys-MDMA, and

lys-MDA Lys-MDA (Lysine-MDA, N-(L-lysinamidyl)-3,4-methylenedioxyamphetamine) is a substituted amphetamine derivative with empathogenic effects, which acts as a prodrug for Methylenedioxyamphetamine, MDA with a slower onset of effects and longer duration ...

has been conducted and completed. Lys-MDMA is being developed by MindMed.

References

External links

Lysine-MDMA - Isomer Design
5-HT1A agonists 5-HT2A agonists 5-HT2B agonists 5-HT2C agonists Amino acids Entactogens Entheogens Euphoriants Experimental antidepressants Experimental entactogens Methamphetamines Methylenedioxyphenethylamines Prodrugs Psychedelic phenethylamines Serotonin-norepinephrine-dopamine releasing agents Serotonin receptor agonists Stimulants TAAR1 agonists VMAT inhibitors {{Psychoactive-stub

See also

References

External links