List Of MeSH Codes (D04)
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The following is a partial list of the "D" codes for
Medical Subject Headings Medical Subject Headings (MeSH) is a comprehensive controlled vocabulary for the purpose of indexing Academic journal, journal articles and books in the Life science, life sciences. It serves as a thesaurus of index terms that facilitates searc ...
(MeSH), as defined by the
United States National Library of Medicine The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. I ...
(NLM). This list continues the information at List of MeSH codes (D03). Codes following these are found at
List of MeSH codes (D05) The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM). This list continues the information at List of MeSH codes (D04). Codes following these are ...
. For other MeSH codes, see
List of MeSH codes The following is a list of the codes for MeSH (Medical Subject Headings), a comprehensive controlled vocabulary for the purpose of index (publishing), indexing journal articles and books in the life sciences. It is a product of the United States ...
. The source for this content is the set o
2006 MeSH Trees
from the NLM.


– polycyclic compounds


–

bridged compounds A bicyclic molecule () is a molecule that features two joined rings. Bicyclic structures occur widely, for example in many biologically important molecules like α-thujene and camphor. A bicyclic compound can be carbocyclic (all of the ring a ...


– bicyclo compounds


– macrocyclic compounds


–

calixarenes A calixarene is a macrocycle or cyclic oligomer based on a methylene-linked phenols. With hydrophobic cavities that can hold smaller molecules or ions, calixarenes belong to the class of cavitands known in host–guest chemistry. Nomenclature ...


– crown compounds

* –
crown ethers In organic chemistry, crown ethers are cyclic chemical compounds that consist of a ring containing several ether groups (). The most common crown ethers are cyclic oligomers of ethylene oxide, the repeating unit being ethyleneoxy, i.e., . Impor ...


–

cyclodextrins Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds. Cyclodextrins are produced from starch by enzymatic conversion. They are used in food, pharmaceuti ...

* – alpha-cyclodextrins * –
beta-cyclodextrins Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds. Cyclodextrins are produced from starch by enzymatic conversion. They are used in food, pharmaceutical ...
* – gamma-cyclodextrins


– cycloparaffins


– ethers, cyclic

* –
crown ethers In organic chemistry, crown ethers are cyclic chemical compounds that consist of a ring containing several ether groups (). The most common crown ethers are cyclic oligomers of ethylene oxide, the repeating unit being ethyleneoxy, i.e., . Impor ...


– lactams, macrocyclic

* –
maytansine Maitansine (INN), or maytansine (USAN), is a cytotoxic agent. It inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. The maytansine binding site and binding mode has been characterized. It is a macrolide of t ...
* –
rifamycins The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium ''Amycolatopsis rifamycinica'' or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective again ...
* –
rifabutin Rifabutin (Rfb) is an antibiotic used to treat tuberculosis and prevent and treat ''Mycobacterium avium'' complex. It is typically only used in those who cannot tolerate rifampin such as people with HIV/AIDS on antiretrovirals. For active tuberc ...
* – streptovaricin * –
rifampin Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), ''Mycobacterium avium'' complex, leprosy, and Legionnaires' disease. It is almost always used tog ...


–

macrolides Macrolides are a class of mostly natural products with a large macrocycle, macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. Macrolides belong to the polyketide class of natural prod ...

* –
amphotericin b Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococ ...
* –
antimycin a Antimycin A (more exactly antimycin A1b) is a secondary metabolite produced by '' Streptomyces'' bacteria and a member of a group of related compounds called antimycins. Antimycin A is classified as an extremely hazardous substance in the Uni ...
* –
brefeldin a Brefeldin A is a lactone antiviral produced by the fungus '' Penicillium brefeldianum''. Brefeldin A inhibits protein transport from the endoplasmic reticulum to the golgi complex indirectly by preventing association of COP-I coat to the Golgi ...
* –
candicidin Candicidin is an antifungal compound obtained from ''Streptomyces griseus''. It is active against some fungi including '' Candida albicans''. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis. This bioactive ...
* –
cytochalasins Cytochalasins are fungal metabolites that have the ability to bind to actin filaments and block polymerization and the elongation of actin. As a result of the inhibition of actin polymerization, cytochalasins can change cellular morphology, inhibit ...
* –
cytochalasin b Cytochalasin B, the name of which comes from the Greek ''cytos'' (cell) and ''chalasis'' (relaxation), is a cell-permeable mycotoxin. It was found that substoichiometric concentrations of cytochalasin B (CB) strongly inhibit network formation by ac ...
* –
cytochalasin d Cytochalasin D is a member of the class of mycotoxins known as cytochalasins. Cytochalasin D is an alkaloid produced by '' Helminthosporium'' and other molds. Cytochalasin D is a cell-permeable and potent inhibitor of actin polymerization. It di ...
* –
epothilones Epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials, epothilones have better efficacy and milder adverse effects than taxanes. Epothilones wer ...
* –
erythromycin Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used ...
* –
azithromycin Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throa ...
* –
clarithromycin Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. This includes strep throat, pneumonia, skin infections, '' H. pylori'' infection, and Lyme disease, among others. Clari ...
* –
erythromycin estolate Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used durin ...
* – erythromycin ethylsuccinate * –
ketolides Ketolides are antibiotics belonging to the macrolide group. Ketolides are derived from erythromycin by substituting the cladinose sugar with a keto-group and attaching a cyclic carbamate group in the lactone ring. These modifications give ketolid ...
* –
roxithromycin Roxithromycin is a semi-synthetic macrolide antibiotic used to treat respiratory tract, urinary and soft tissue infections. It is a derivative of erythromycin - comprising the same 14-membered lactone ring - with an oxime-based side chain attac ...
* –
ivermectin Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, it is used to treat infestations including head lice ...
* –
josamycin Josamycin is a macrolide antibiotic. It was isolated by Hamao Umezawa and his colleagues from strains of '' Streptomyces narbonensis'' var. ''josamyceticus'' var. ''nova'' in 1964. It is currently sold in various countries.Brand examples are: ...
* – leucomycins * – kitasamycin * –
spiramycin Spiramycin is a macrolide antibiotic and antiparasitic. It is used to treat toxoplasmosis and various other infections of soft tissues. Although used in Europe, Canada and Mexico, spiramycin is still considered an experimental drug in the Unite ...
* – lucensomycin * – mepartricin * – miocamycin * –
natamycin Natamycin, also known as pimaricin, is an antifungal medication used to treat fungal infections around the eye. This includes infections of the eyelids, conjunctiva, and cornea. It is used as eyedrops. Natamycin is also used in the food in ...
* –
nystatin Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. It is used to treat ''Candida (fungus), Candida'' infections of the skin including diaper rash, Candidiasis, thrush, esophageal candidiasis, and vaginal ...
* –
oleandomycin Oleandomycin is a macrolide antibiotic. It is synthesized from strains of ''Streptomyces antibioticus''. It is weaker than erythromycin. It used to be sold under the brand name Sigmamycine, combined with tetracycline, and made by the company R ...
* –
troleandomycin Troleandomycin (TAO for short) is a macrolide antibiotic. It was sold in Italy (branded Triocetin) and Turkey (branded Tekmisin). It is no longer sold in Italy as of 2018. The drug's mode of action is to bind to the ribosome, specifically in the ...
* –
oligomycins Oligomycins are macrolides created by ''Streptomyces'' that are strong antibacterial agents but are often poisonous to other organisms, including humans. Function Oligomycins have use as antibiotics. However, in humans, they have limited or no ...
* – rutamycin * –
sirolimus Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis ...
* –
tacrolimus Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After Allotransplantation, allogenic organ transplant, the risk of organ Transplant rejection, rejection is moderate. To lower the risk of organ rejectio ...
* –
tylosin Tylosin is a macrolide antibiotic and bacteriostatic feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. It is found naturally as a ferme ...


– peptides, cyclic

* – alamethicin * –
amanitins Amanitin may refer to several related amatoxins: * α-Amanitin * β-Amanitin * γ-Amanitin * ε-Amanitin See also * Amatoxin, a class of toxic compounds that include the amanitins * Amanin Amanin is a cyclic peptide. It is one of the amatox ...
* –
bacitracin Bacitracin is a polypeptide antibiotic. It is a mixture of related cyclic peptides produced by '' Bacillus licheniformis'' bacteria, that was first isolated from the variety "Tracy I" ( ATCC 10716) in 1945. These peptides disrupt Gram-positiv ...
* – capreomycin sulfate * –
cyclosporins The cyclosporins are a group of macrolides isolated from fungi and used as immunosuppresant drugs, for example after transplant surgery. They are nonribosomal peptide synthesized by cyclosporin synthetase. *Cyclosporin A Ciclosporin, also s ...
* –
cyclosporine Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, ecz ...
* –
dactinomycin Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of o ...
* –
daptomycin Daptomycin, sold under the brand name Cubicin among others, is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. Daptomycin was removed from the WHO Model List of Ess ...
* –
depsipeptides A depsipeptide is a peptide in which one or more of its amide, -C(O)NHR-, groups are replaced by the corresponding ester, -C(O)OR-. Many depsipeptides have both peptide and ester linkages. Elimination of the N–H group in a peptide structure result ...
* –
valinomycin Valinomycin is a naturally occurring dodecadepsipeptide used in the transport of potassium and as an antibiotic. Valinomycin is obtained from the cells of several ''Streptomyces'' species, '' S. fulvissimus'' being a notable one. It is a member o ...
* –
echinomycin Echinomycin is a peptide antibiotic. It is a dimer of two peptides creating a cyclic structure. It contains a bicyclic aromatic chromophore that is attached to the dimerized cyclic peptide core and a thioacetal bridge. It intercalates into DNA a ...
* –
ferrichrome Ferrichrome is a cyclic hexa-peptide that forms a complex with iron atoms. It is a siderophore composed of three glycine and three modified ornithine residues with hydroxamate groups N(OH)C(=O)C- The 6 oxygen atoms from the three hydroxamate g ...
* – mycobacillin * –
nisin Nisin is a polycyclic antibacterial peptide produced by the bacterium ''Lactococcus lactis'' that is used as a food preservative. It has 34 amino acid residues, including the uncommon amino acids lanthionine (Lan), methyllanthionine (MeLan), dideh ...
* –
octreotide Octreotide, sold under the brand name Sandostatin among others, is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was ...
* – phalloidine * – polymyxins * –
colistin Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections including pneumonia. These may involve bacteria such as ''Pseudomonas aeruginosa'', ''Klebsiella ...
* –
polymyxin b Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. While it is useful for many Gram negative infections, it is not useful for Gram positive infe ...
* – streptogramins * – mikamycin * –
pristinamycin Pristinamycin (INN), also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, ...
* – streptogramin group a * –
streptogramin a Streptogramin A is a group of antibiotics within the larger family of antibiotics known as streptogramins. They are synthesized by the bacteria '' Streptomyces virginiae''. The streptogramin family of antibiotics consists of two distinct groups: ...
* – streptogramin group b * –
streptogramin b Streptogramin B is a subgroup of the streptogramin antibiotics family. These natural products are cyclic hexa- or hepta depsipeptides produced by various members of the genus of bacteria ''Streptomyces''. Many of the members of the streptogramins re ...
* – vernamycin b * –
virginiamycin Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA (virginiamycin M1) and virginiamycin S1. Virginiamycin is used in the fuel ethanol Ethanol (als ...
* –
streptogramin a Streptogramin A is a group of antibiotics within the larger family of antibiotics known as streptogramins. They are synthesized by the bacteria '' Streptomyces virginiae''. The streptogramin family of antibiotics consists of two distinct groups: ...
* –
thiostrepton Thiostrepton is a natural cyclic oligopeptide antibiotic of the thiopeptide class, derived from several strains of streptomycetes, such as '' Streptomyces azureus'' and '' Streptomyces laurentii''. Thiostrepton is a natural product of the ribo ...
* –
viomycin Viomycin is a member of the tuberactinomycin family, a group of nonribosomal peptide antibiotics exhibiting anti-tuberculosis activity. The tuberactinomycin family is an essential component in the drug cocktail currently used to fight infection ...
* – enviomycin


–

tetrapyrroles Tetrapyrroles are a class of chemical compounds that contain four pyrrole or pyrrole-like rings. The pyrrole/pyrrole derivatives are linked by ( or units), in either a linear or a cyclic fashion. Pyrroles are a five-atom ring with four carbon ...

* –
bile pigments Bilins, bilanes or bile pigments are biological pigments formed in many organisms as a metabolic product of certain porphyrins. Bilin (also called bilichrome) was named as a bile pigment of mammals, but can also be found in lower vertebrates, inve ...
* –
bilirubin Bilirubin (BR) (adopted from German, originally bili—bile—plus ruber—red—from Latin) is a red-orange compound that occurs in the normcomponent of the straw-yellow color in urine. Another breakdown product, stercobilin, causes the brown ...
* – biliverdine * –
urobilin Urobilin is the chemical primarily responsible for the yellow color of urine. It is a linear tetrapyrrole compound that, along with the related colorless compound urobilinogen, are degradation products of the cyclic tetrapyrrole heme. Metabolis ...
* –
urobilinogen Urobilinogen is a yellow by-product of bilirubin reduction. It is formed in the intestines by the bacterial enzyme bilirubin reductase. About half of the urobilinogen formed is reabsorbed and taken up via the portal vein to the liver, enters circu ...
* –
chlorophyll Chlorophyll is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words (, "pale green") and (, "leaf"). Chlorophyll allows plants to absorb energy ...
* –
bacteriochlorophylls Bacteriochlorophylls (BChl) are photosynthetic pigments that occur in various phototrophic bacteria. They were discovered by C. B. van Niel in 1932. They are related to chlorophylls, which are the primary pigments in plants, algae, and cyanobacte ...
* – chlorophyllides * – pheophytins * –
protochlorophyllide Protochlorophyllide,KEGG compound database entr/ref> or monovinyl protochlorophyllide, is an intermediate in the biosynthesis of chlorophyll ''a''. It lacks the phytol side-chain of chlorophyll and the reduced pyrrole in ring D. Protochlorophy ...
* –
corrinoids Corrinoids are a group of compounds based on the skeleton of corrin, a cyclic system containing four pyrrole rings similar to porphyrins. These include compounds based on octadehydrocorrin, which has the trivial name corrole. The cobalamins (vit ...
* – vitamin b 12 * – cobamides * –
hydroxocobalamin Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. Other uses include treatment ...
* –
porphyrins Porphyrins ( ) are heterocyclic, macrocyclic, organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (). In vertebrates, an essential member of the porphyrin group is heme, whi ...
* – coproporphyrins * – deuteroporphyrins * – etioporphyrins * – hematoporphyrins * – hematoporphyrin derivative * – dihematoporphyrin ether * – mesoporphyrins * – metalloporphyrins * –
chlorophyll Chlorophyll is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words (, "pale green") and (, "leaf"). Chlorophyll allows plants to absorb energy ...
* –
bacteriochlorophylls Bacteriochlorophylls (BChl) are photosynthetic pigments that occur in various phototrophic bacteria. They were discovered by C. B. van Niel in 1932. They are related to chlorophylls, which are the primary pigments in plants, algae, and cyanobacte ...
* – chlorophyllides * –
protochlorophyllide Protochlorophyllide,KEGG compound database entr/ref> or monovinyl protochlorophyllide, is an intermediate in the biosynthesis of chlorophyll ''a''. It lacks the phytol side-chain of chlorophyll and the reduced pyrrole in ring D. Protochlorophy ...
* –
heme Heme (American English), or haem (Commonwealth English, both pronounced /Help:IPA/English, hi:m/ ), is a ring-shaped iron-containing molecule that commonly serves as a Ligand (biochemistry), ligand of various proteins, more notably as a Prostheti ...
* –
hemin Hemin (haemin; ferric chloride heme) is an iron-containing porphyrin with chlorine that can be formed from a heme group, such as heme B found in the hemoglobin of human blood. Chemistry Hemin is protoporphyrin IX containing a ferric iron (Fe ...
* – porphyrinogens * – coproporphyrinogens * –
uroporphyrinogens Uroporphyrinogens are cyclic tetrapyrroles with four propionic acid groups ("P" groups) and four acetic acid groups ("A" groups). There are four forms, which vary based upon the arrangements of the "P" and "A" groups (in clockwise order): * In the ...
* – protoporphyrins * – uroporphyrins


–

trichothecenes Trichothecenes constitute a large group of chemically related mycotoxins. They are produced by Fungus, fungi of the genera ''Fusarium'', ''Myrothecium'', ''Trichoderma'', ''Podostroma'', ''Trichothecium'', ''Cephalosporium'', ', ''Stachybotrys'' ...

* –
t-2 toxin T-2 mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of ''Fusarium'' spp. fungus which is toxic to humans and other animals. The clinical condition it causes is ''alimentary toxic aleukia'' and a host of symptom ...
* – trichodermin


– polycyclic hydrocarbons, aromatic


– acenaphthenes


–

anthracenes Anthracene is a solid polycyclic aromatic hydrocarbon (PAH) of formula C14H10, consisting of three fused benzene rings. It is a component of coal tar. Anthracene is used in the production of the red dye alizarin and other dyes, as a scintilla ...

* –
dithranol Dithranol (INN) or anthralin (USAN and former BAN) is a hydroxyanthrone, anthracene derivative, and is used in medications applied to the skin of people with psoriasis. It is available as creams, ointment or pastes in 0.1 to 2% strengths (Dritho ...
(anthralin) * –
anthraquinones ''For the parent molecule 9,10-anthraquinone, see anthraquinone'' Anthraquinones (also known as anthraquinonoids) are a class of naturally occurring phenolic compounds based on the 9,10-anthraquinone skeleton. They are widely used industrially a ...
* –
carmine Carmine ()also called cochineal (when it is extracted from the Cochineal, cochineal insect), cochineal extract, crimson Lake pigment, lake, or carmine lake is a pigment of a bright-red color obtained from the aluminium coordination complex, compl ...
* – cascara * –
emodin Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is an organic compound. Classified as an anthraquinone, it can be isolated from rhubarb, buckthorn, and Japanese knotweed ('' Reynoutria japonica'' syn. ''Polygonum cuspidatum''). Emodin is part ...
* –
mitoxantrone Mitoxantrone (INN, BAN, USAN; also known as Mitozantrone in Australia; trade name Novantrone) is an anthracenedione antineoplastic agent. Uses Mitoxantrone is used to treat certain types of cancer, mostly acute myeloid leukemia. It improves th ...
* –
maprotiline Maprotiline, sold under the brand name Ludiomil among others, is a tetracyclic antidepressant (TeCA) that is used in the treatment of depression (mood), depression. It may alternatively be classified as a tricyclic antidepressant (TCA), specific ...


–

azulenes Azulene is an aromatic organic compound and an isomer of naphthalene. Naphthalene is colourless, whereas azulene is dark blue. The compound is named after its colour, as "azul" is Spanish for blue. Two terpenoids, vetivazulene (4,8-dimethyl-2-is ...


– benz(a)anthracenes

* – 9,10-dimethyl-1,2-benzanthracene * –
methylcholanthrene Methylcholanthrene is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures. Methylcholanthrene is also known as 3-methylcholanthrene, 20-methylcholanthrene or the IUPAC name 3-methy ...
* –
perylene Perylene or perilene is a polycyclic aromatic hydrocarbon with the chemical formula C20H12, occurring as a brown solid. It or its derivatives may be carcinogenic, and it is considered to be a hazardous pollutant. In cell membrane cytochemistry, ...


–

benzocycloheptenes Benzocycloheptenes are cycloheptenes with additional benzene rings attached. Most have two benzene rings, and are called dibenzocycloheptenes. Some benzocycloheptenes and substituted benzocycloheptenes have medical uses as antihistamines, antic ...

* –
dibenzocycloheptenes Dibenzocycloheptene (also known as dibenzosuberane and dibenzocycloheptadiene) is a tricyclic chemical compound featuring two benzene rings bound to a cycloheptene group. It is an occasional motif in synthetic organic chemistry. Various tricycl ...
* –
amitriptyline Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headac ...
* –
butaclamol Butaclamol (AY-23,028) is a type of antipsychotic which was never marketed. Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist. Synthesis: Review: Book chapter:Chronicles of Drug Discovery, V ...
* –
cyproheptadine Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine, first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 a ...
* –
loratadine Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in whic ...
* – dizocilpine maleate * –
nortriptyline Nortriptyline, sold under the brand name Aventyl, among others, is a tricyclic antidepressant. This medicine is also sometimes used for neuropathic pain, attention deficit hyperactivity disorder (ADHD), smoking cessation and anxiety. Its use f ...
* –
protriptyline Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine. Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes use ...


–

fluorenes Fluorene , or 9''H''-fluorene is an organic compound with the formula (C6H4)2CH2. It forms white crystals that exhibit a characteristic, aromatic odor similar to that of naphthalene. Despite its name, it does not contain the element fluorine, but ...

* –
2-acetylaminofluorene 2-Acetylaminofluorene (AAF, 2-AAF) is a carcinogenic and mutagenic derivative of fluorene. It is used as a biochemical tool in the study of carcinogenesis. It induces tumors in a number of species in the liver, bladder and kidney. The metabolism ...
* – acetoxyacetylaminofluorene * – hydroxyacetylaminofluorene * –
tilorone Tilorone (trade names Amixin, Lavomax and others) is the first recognized Chemical synthesis, synthetic, small molecular weight compound that is an orally active interferon inducer. It is used as an antiviral drug in some countries which do not r ...


–

indenes Indene is an aromatic, polycyclic hydrocarbon with chemical formula . It is composed of a benzene ring fused with a cyclopentene ring. This flammable liquid is colorless although samples often are pale yellow. The principal industrial use of i ...

* –
dimethindene Dimetindene, also sold under the brand name Fenistil, is an antihistamine/anticholinergic. It is a first generation selective H1 antagonist. Dimetindene is an atypical first generation H1 antagonist as it only minimally passes across the blood†...
* – indans * –
aprindine Aprindine is a Class 1b antiarrhythmic agent and has antiarrhythmic properties similar to lidocaine Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. I ...
* –
ninhydrin Ninhydrin (2,2-dihydroxyindane-1,3-dione) is an organic compound with the formula C6H4(CO)2C(OH)2. It is used to detect ammonia and amines. Upon reaction with these amines, ninhydrin gets converted into deep blue or purple derivatives, which are ...
* –
phenindione Phenindione is an anticoagulant which functions as a Vitamin K antagonist. Phenindione was introduced in the early 1950s. It acts similar to warfarin Warfarin, sold under the brand name Coumadin among others. It is used as an anticoagul ...
* –
sulindac Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed as Clinoril. Imbaral (not to be confused with mebaral) is another name for this drug. Its name is derived from sul(finyl)+ ind(ene)+ ac(eti ...


– naphthacenes

* –
anthracyclines Anthracyclines are a class of drugs used in cancer chemotherapy that are extracted from '' Streptomyces peucetius'' bacterium. These compounds are used to treat many cancers, including leukemias, lymphomas, breast, stomach, uterine, ovarian, b ...
* –
aclarubicin Aclarubicin (INN) or aclacinomycin A is an anthracycline drug that is used in the treatment of cancer in China. It was previously approved for use in Europe but was discontinued in 2004 due to being rarely prescribed and unprofitable. However, ...
* –
daunorubicin Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma. I ...
* – carubicin * –
doxorubicin Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used toge ...
* –
epirubicin Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in ...
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idarubicin Idarubicin or 4-demethoxydaunorubicin is an anthracycline antileukemic drug. It inserts itself into DNA and prevents DNA unwinding by interfering with the enzyme topoisomerase II. It is an analog of daunorubicin, but the absence of a methoxy gro ...
* – nogalamycin * – menogaril * –
plicamycin Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by '' Streptomyces plicatus''. It is an RNA synthesis inhibitor. The manufacturer discontinued production in 2000. Several different struc ...
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tetracyclines Tetracyclines are a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of ''Streptomyces'' bacteria or produced semi-synthetically from those isolated compounds. ...
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chlortetracycline Chlortetracycline (trade name Aureomycin, Lederle Laboratories) is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 at Lederle Laboratories under the supervision of Yellapragada Subbarow and Benjamin ...
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demeclocycline Demeclocycline (INN, BAN, USAN, brand name Declomycin) is a tetracycline antibiotic which was derived from a mutant strain of ''Streptomyces aureofaciens''. Uses Demeclocycline is officially indicated for the treatment of various types of bact ...
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doxycycline Doxycycline is a Broad-spectrum antibiotic, broad-spectrum antibiotic of the Tetracycline antibiotics, tetracycline class used in the treatment of infections caused by bacteria and certain parasites. It is used to treat pneumonia, bacterial p ...
* – lymecycline * – methacycline * –
minocycline Minocycline, sold under the brand name Minocin among others, is a tetracycline antibiotic medication used to treat a number of bacterial infections such as some occurring in certain forms of pneumonia. It is generally (but not always) less pre ...
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oxytetracycline Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot ...
* – rolitetracycline * –
tetracycline Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis. It is available in oral an ...


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naphthalenes Naphthalene is an organic compound with formula . It is the simplest polycyclic aromatic hydrocarbon, and is a white crystalline solid with a characteristic odor that is detectable at concentrations as low as 0.08  ppm by mass. As an aromati ...

* – bunaftine * –
carbaryl Carbaryl (1-naphthyl methylcarbamate) is a chemical in the carbamate family used chiefly as an insecticide. It is a white crystalline solid previously sold under the brand name Sevin, which was a trademark of the Bayer Company. Union Carbide disc ...
* – dansyl compounds * –
lovastatin Lovastatin, sold under the brand name Mevacor among others, is a statin medication, to treat high blood cholesterol and reduce the risk of cardiovascular disease. Its use is recommended together with lifestyle changes. It is taken by mouth. ...
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simvastatin Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease hyperlipidemia, elevated lipid levels. It is also used to decrease t ...
* – naphthaleneacetic acids * –
naproxen Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It ...
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naphthalenesulfonates Naphthalenesulfonates are derivatives of sulfonic acid that contain a naphthalene functional unit. A subfamily of compounds are the aminonaphthalenesulfonic acids, which describes precursors to several azo dyes. Amaranth Na-Salz.svg, amaranth ...
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amaranth dye ''Amaranthus'' is a cosmopolitan group of more than 50 species which make up the genus of annual or short-lived perennial plants collectively known as amaranths. Some names include " prostrate pigweed" and " love lies bleeding". Some amaranth ...
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amido black Amido black 10B is an amino acid staining azo dye used in biochemical research to stain for total protein on transferred membrane blots, such as the western blot. It is also used in criminal investigations to detect blood present with latent finge ...
* – anilino naphthalenesulfonates * – congo red * –
Evans blue Evans blue may refer to: * Evans blue (dye) * Evans Blue, Canadian rock band {{disambiguation ...
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suramin Suramin is a medication used to treat African sleeping sickness and river blindness. It is the treatment of choice for sleeping sickness without central nervous system involvement. It is given by injection into a vein. Suramin causes a fai ...
* – trypan blue * –
naphthols Naphthol may refer to: * 1-Naphthol * 2-Naphthol {{Short pages monitor