Ferdinand-Jean Darier (; 26 April 1856 – 1938) was a

French French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), ...

physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...

pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...

and

dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medi ...

called the "father of modern dermatology in France".

Career

Medical

Born in Pest,Historisches Lexikon der Schweiz
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Hungary Hungary is a landlocked country in Central Europe. Spanning much of the Pannonian Basin, Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the south, Croatia and ...

to French parents, Darier studied with

Louis-Antoine Ranvier Louis-Antoine Ranvier (2 October 1835 – 22 March 1922) was a French physician, pathologist, anatomist and histologist, who discovered the nodes of Ranvier, regularly spaced discontinuities of the myelin sheath, occurring at varying interval ...

(1835–1922) at the

Collège de France The (), formerly known as the or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment () in France. It is located in Paris near La Sorbonne. The has been considered to be France's most ...

. Darier discovered several diseases, most notably

Darier's disease Darier's disease (DD) is a rare, genetic skin disorder. It is an autosomal dominant disorder, that is, if one parent has DD, there is a 50% chance than a child will inherit DD. It was first reported by French dermatologist Ferdinand-Jean Darier ...

, a peculiar figurate

erythema Erythema (, ) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology inc ...

, which he identified in 1889 as ''psorodermose folliculaire végétante''. The other diseases were a follicular keratosis (Darier-White syndrome),

dermatofibrosarcoma Dermatofibrosarcoma protuberans (DFSP) is a rare locally aggressive malignant cutaneous soft-tissue sarcoma. DFSP develops in the connective tissue cells in the middle layer of the skin (dermis). Estimates of the overall occurrence of DFSP in the U ...

(Darier-Ferrand disease), erythema annularis, subcutaneous sarcoidosis (Darier-Roussy sarcoid), and a sign,

Darier's sign Darier's sign is a change observed after stroking lesions on the skin of a person with systemic mastocytosis or urticaria pigmentosa. In general, the skin becomes swollen, itchy and red. This is a result of compression of mast cells, which ar ...

observed in

mastocytosis Mastocytosis, a type of mast cell A mast cell (also known as a mastocyte or a labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. Specifically, it is a type of granulocyte derived from ...

. From 1909 to 1922, Darier was head of the clinical department at the

Hôpital Saint-Louis Hôpital Saint-Louis () is a hospital in Paris, France. It was built in 1611 by architect Claude Vellefaux at the request of Henry IV of France. It is part of the Assistance publique - Hôpitaux de Paris hospital system, and it is located at 1 a ...

. He was one of the "big five" of the Paris School of Dermatology, along with Ernest Henri Besnier (1831–1909),

Louis-Anne-Jean Brocq Louis-Anne-Jean Brocq (; 1 February 1856 – 18 December 1928) was a French dermatologist born in Laroque-Timbaut, a village in the department of Lot-et-Garonne. He practiced medicine in Paris at the Hospice la Rochefoucauld, the Hôpital Broca, ...

(1856–1928),

Raymond Sabouraud Raymond Jacques Adrien Sabouraud (; 24 November 1864 – 4 February 1938) was a French physician born in Nantes. He specialized in dermatology and mycology, and was also an accomplished painter and sculptor. He studied medicine in Nantes and ...

(1864–1938) and

Jean Alfred Fournier Jean Alfred Fournier (; 21 May 1832 – 23 December 1914) was a French dermatologist who specialized in the study of venereal disease. Biography As a young man Fournier served as an intern at the Hôpital du Midi as an understudy to Philippe ...

(1832–1915). Darier wrote the dermatology textbook ''Précis de dermatologie'', which was published in 1909 and translated into Spanish, German and English. He was also the editor of the dermatological encyclopedia ''Nouvelle Pratique Dermatologique'', which was published in eight volumes, beginning in 1936.

Political

Besides his medical activities, Darier was the

mayor In many countries, a mayor is the highest-ranking official in a Municipal corporation, municipal government such as that of a city or a town. Worldwide, there is a wide variance in local laws and customs regarding the powers and responsibilitie ...

of the town

Longpont-sur-Orge Longpont-sur-Orge (, literally ''Longpont on Orge'') is a commune in the Essonne department in Île-de-France in northern France. From 1954 to 1962, the villa in Longpont-sur-Orge owned by William and Noma Copley served as a social hub and a ...

from 1925 to 1935.

List of works

* ''De l'artérite syphilitique'' (1904) * ''Précis de dermatologie'' (1909) * ''Nouvelle Pratique Dermatologique'' (1936)

Sources

{{DEFAULTSORT:Darier, Ferdinand-Jean 1856 births 1938 deaths French dermatologists French pathologists Physicians from Budapest