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Ferdinand-Jean Darier
Ferdinand-Jean Darier (26 April 1856 – 1938) was a French physician, pathologist and dermatologist called the "father of modern dermatology in France". Career Medical Born in Budapest, Hungary to French parents, Darier studied with Louis-Antoine Ranvier (1835–1922) at the Collège de France. Darier discovered several diseases, most notably Darier's disease, a peculiar figurate erythema, which he identified in 1889 as ''psorodermose folliculaire végétante''. The other diseases were a follicular keratosis (Darier-White syndrome), acanthosis nigricans, dermatofibrosarcoma (Darier-Ferrand disease), erythema annularis, subcutaneous sarcoidosis (Darier-Roussy sarcoid), and a sign, Darier's sign observed in mastocytosis. From 1909 to 1922, Darier was head of the clinical department at the Hôpital Saint-Louis. He was one of the "big five" of the Paris School of Dermatology, along with Ernest Henri Besnier (1831–1909), Louis-Anne-Jean Brocq (1856–1928), Raymond S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Budapest
Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population of 1,752,286 over a land area of about . Budapest, which is both a city and county, forms the centre of the Budapest metropolitan area, which has an area of and a population of 3,303,786; it is a primate city, constituting 33% of the population of Hungary. The history of Budapest began when an early Celtic settlement transformed into the Roman town of Aquincum, the capital of Lower Pannonia. The Hungarians arrived in the territory in the late 9th century, but the area was pillaged by the Mongols in 1241–42. Re-established Buda became one of the centres of Renaissance humanist culture by the 15th century. The Battle of Mohács, in 1526, was followed by nearly 150 years of Ottoman rule. After the reconquest of Buda in 1686, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acanthosis Nigricans
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas. It is associated with endocrine dysfunction, especially insulin resistance and hyperinsulinaemia, as seen in diabetes mellitus. This activates the insulin-like growth factor receptors, which leads to proliferation of keratinocytes, fibroblasts and other cells in the skin. Activation of other growth factor receptors such as fibroblast growth factor receptors or epidermal growth factor receptor can also be responsible. Signs and symptoms Acanthosis nigricans may present with thickened, velvety, relatively darker areas of skin on the neck, armpit and in skin folds. Causes It typically occurs in individuals younger than age 40, is associated with insulin resistance, Type 2 diabetes, obesity or endocrinopathies, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Dermatologists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * Frenc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1938 Deaths
Events January * January 1 ** The Constitution of Estonia#Third Constitution (de facto 1938–1940, de jure 1938–1992), new constitution of Estonia enters into force, which many consider to be the ending of the Era of Silence and the authoritarian regime. ** state-owned enterprise, State-owned railway networks are created by merger, in France (SNCF) and the Netherlands (Nederlandse Spoorwegen – NS). * January 20 – King Farouk of Egypt marries Safinaz Zulficar, who becomes Farida of Egypt, Queen Farida, in Cairo. * January 27 – The Honeymoon Bridge (Niagara Falls), Honeymoon Bridge at Niagara Falls, New York, collapses as a result of an ice jam. February * February 4 ** Adolf Hitler abolishes the War Ministry and creates the Oberkommando der Wehrmacht (High Command of the Armed Forces), giving him direct control of the German military. In addition, he dismisses political and military leaders considered unsympathetic to his philosophy or policies. Gene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1856 Births
Events January–March * January 8 – Borax deposits are discovered in large quantities by John Veatch in California. * January 23 – American paddle steamer SS Pacific (1849), SS ''Pacific'' leaves Liverpool (England) for a transatlantic voyage on which she will be lost with all 186 on board. * January 24 – U.S. President Franklin Pierce declares the new Free-Stater (Kansas), Free-State Topeka Constitution, Topeka government in "Bleeding Kansas" to be in rebellion. * January 26 – First Battle of Seattle (1856), Battle of Seattle: Marines from the suppress an indigenous uprising, in response to Governor Stevens' declaration of a "war of extermination" on Native communities. * January 29 ** The 223-mile North Carolina Railroad is completed from Goldsboro, North Carolina, Goldsboro through Raleigh, North Carolina, Raleigh and Salisbury, North Carolina, Salisbury to Charlotte, North Carolina, Charlotte. ** Queen Victoria institutes the Victoria Cross ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Longpont-sur-Orge
Longpont-sur-Orge (, literally ''Longpont on Orge'') is a commune in the Essonne department in Île-de-France in northern France. From 1954 to 1962, the villa in Longpont-sur-Orge owned by William and Noma Copley served as a social hub and a central gathering place in the postwar era for a community of Surrealists to reunite after their dispersal during the war. Among the artists who frequented the villa located at 27, rue du Docteur Darier were Man Ray, Henri Matisse, Marcel Duchamp, Roland Penrose, Lee Miller, and British architect Maxwell Fry. Brico Dépôt, a subsidiary of Kingfisher plc, has its head office in Longpont-sur-Orge. Population Inhabitants of Longpont-sur-Orge are known as ''Longipontains'' in French. Education The commune has the following primary school groups, or Groups of preschools (''maternelles'') and elementary schools: Groupe scolaire de Lormoy, Groupe scolaire des Échassons, Groupe scolaire Jean Ferrat (primary only). Two nearby secondary schoo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mayor
In many countries, a mayor is the highest-ranking official in a municipal government such as that of a city or a town. Worldwide, there is a wide variance in local laws and customs regarding the powers and responsibilities of a mayor as well as the means by which a mayor is elected or otherwise mandated. Depending on the system chosen, a mayor may be the chief executive officer of the municipal government, may simply chair a multi-member governing body with little or no independent power, or may play a solely ceremonial role. A mayor's duties and responsibilities may be to appoint and oversee municipal managers and employees, provide basic governmental services to constituents, and execute the laws and ordinances passed by a municipal governing body (or mandated by a state, territorial or national governing body). Options for selection of a mayor include direct election by the public, or selection by an elected governing council or board. The term ''mayor'' shares a linguistic o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean Alfred Fournier
Jean Alfred Fournier () (21 May 1832 – 25 December 1914) was a French dermatologist who specialized in the study of venereal disease. Biography As a young man he served as an interne at the Hôpital du Midi as an understudy to Philippe Ricord (1800–1889). In 1863 he became ''médecine des hôpitaux'', and from 1867 worked with Augustin Grisolle (1811–1869) at the Hôtel-Dieu de Paris. In 1876 he was appointed ''chef de service'' at the Hôpital Saint-Louis, later becoming a member of the ''Académie de Médecine'' (1880). His main contribution to medical science was the study of congenital syphilis, of which he provided a description of in 1883. In his numerous publications he stressed the importance of syphilis being the cause of degenerative diseases. In addition, in 1901 he founded an organization devoted to spreading knowledge to combat syphilis, called the ''Société Française de Prophylaxie Sanitaire et Morale''. His name is associated with the following three ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raymond Sabouraud
Raymond Jacques Adrien Sabouraud (24 November 1864 – 4 February 1938) was a French physician born in Nantes. He specialized in dermatology and mycology, and was also an accomplished painter and sculptor. He studied medicine in Nantes and Paris, and worked as a hospital interne at the Hôpital Saint-Louis under Ernest Besnier and at the Hôpital des Enfants-Assistés under Edouard Francis Kirmisson. Afterwards he studied bacteriology with Pierre Paul Émile Roux at the Pasteur Institute. In 1894 he received his doctorate, and he later served as chief of Jean Alfred Fournier's laboratory at the Hôpital Saint-Louis.''Raymond Sabouraud'' @ Who Named It [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis-Anne-Jean Brocq
Louis-Anne-Jean Brocq (1 February 1856 – 18 December 1928) was a French dermatologist born in Laroque-Timbaut, a village in the department of Lot-et-Garonne. He practiced medicine in Paris at the Hospice la Rochefoucauld, the Hôpital Broca, and from 1906 to 1921, the Hôpital Saint-Louis. As a young physician he studied and worked with Jean Alfred Fournier (1832–1915), Jean Baptiste Emile Vidal (1825–1893) and Ernest Henri Besnier (1831–1909). Brocq provided early, comprehensive descriptions of numerous skin disorders, including keratosis pilaris, parapsoriasis and a form of dermatitis called "Duhring-Brocq disease" (named with Louis Adolphus Duhring and sometimes referred to as dermatitis herpetiformis). Other eponymous skin diseases named after him are " Brocq's pseudopelade", a condition involving progressive scarring of the scalp, and "Brocq-Pautrier angiolupoid", a specific type of sarcoidosis of the skin named in conjunction with Dr. Lucien-Marie Pautrier (18 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernest Henri Besnier
Ernest Henri Besnier (; 21 April 1831 – 15 May 1909, Paris) was a French dermatologist and medical director of the Hôpital Saint-Louis in Paris. He was a native of Honfleur, département Calvados. He studied medicine in Paris, where in 1857 he received his medical doctorate. In 1863 he became ''médecin des hôpitaux''. In 1873 he succeeded Pierre-Antoine-Ernest Bazin (1807–1878) as dermatologist at the Hôpital Saint Louis, where later the same year, he was named director. He built histopathology and parasitology laboratories at the hospital, and is credited with originating the term biopsy for tissue samples. In 1889 he proved an early description of skin lesions associated with sarcoidosis, introducing the name "lupus pernio". With Pierre Adolphe Adrien Doyon (1827–1907), he founded the medical journal ''Annales de dermatologie et de syphiligraphie''. Besnier attempted to balance the differences between the French and Viennese approaches to dermatological medicine, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mastocytosis
Mastocytosis, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called ''mastocytes'') and CD34+ mast cell precursors. People affected by mastocytosis are susceptible to a variety of symptoms, including itching, hives, and anaphylactic shock, caused by the release of histamine and other pro-inflammatory substances from mast cells. Signs and symptoms When mast cells undergo degranulation, the substances that are released can cause a number of symptoms that can vary over time and can range in intensity from mild to severe. Because mast cells play a role in allergic reactions, the symptoms of mastocytosis often are similar to the symptoms of an allergic reaction. They may include, but are not limited to * Fatigue * Skin lesions ('' urticaria pigmentosa''), itching, and dermatographic ''urticaria'' (skin writing) * "Darier's Sign", a reaction to stroking or scratching of urtica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
