Edith Potter
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Edith Louise Potter (1901 – March 22, 1993) was an American physician and scientist who established the field of perinatal pathology. Potter made early contributions to the understanding of
Rh disease Rh disease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the fetus and newborn (HDFN). The term "Rh disease" is commonly used to refer to HDFN due to a ...
. She established the link between a characteristic facial appearance and the absence of fetal kidneys, an association that became known as
Potter sequence Potter sequence is the atypical physical appearance of a baby due to oligohydramnios experienced when in the uterus. It includes clubbed feet, pulmonary hypoplasia and cranial anomalies related to the oligohydramnios. Oligohydramnios is the decr ...
. A native of
Iowa Iowa ( ) is a U.S. state, state in the upper Midwestern United States, Midwestern region of the United States. It borders the Mississippi River to the east and the Missouri River and Big Sioux River to the west; Wisconsin to the northeast, Ill ...
, Potter received a medical degree and a Ph.D. at the
University of Minnesota The University of Minnesota Twin Cities (historically known as University of Minnesota) is a public university, public Land-grant university, land-grant research university in the Minneapolis–Saint Paul, Twin Cities of Minneapolis and Saint ...
. She practiced pathology at the
Chicago Lying-in Hospital The University of Chicago Medical Center, branded as UChicago Medicine, is a nationally ranked academic medical center located in Hyde Park on the South Side of Chicago. It is the flagship campus for The University of Chicago Medicine system and ...
for more than 30 years. After retiring from medical practice, Potter became known for her involvement in
horticulture Horticulture (from ) is the art and science of growing fruits, vegetables, flowers, trees, shrubs and ornamental plants. Horticulture is commonly associated with the more professional and technical aspects of plant cultivation on a smaller and mo ...
.


Early life

Potter was born on September 26, 1901, in
Clinton, Iowa Clinton is a city in and the county seat of Clinton County, Iowa, United States. It borders the Mississippi River. The population was 24,469 as of 2020 United States census, 2020. Clinton, along with DeWitt, Iowa, DeWitt (also located in Clinto ...
, to William Harvey Potter and the former Edna Rugg Holmes. Her father was a locomotive engineer. She lived in Wisconsin and Minnesota as a child. She attended the
University of Minnesota The University of Minnesota Twin Cities (historically known as University of Minnesota) is a public university, public Land-grant university, land-grant research university in the Minneapolis–Saint Paul, Twin Cities of Minneapolis and Saint ...
, where she earned an undergraduate degree and a medical degree. Potter interned in Minneapolis, pursued additional postgraduate study in Vienna, and then entered private medical practice in Minnesota for five years. She earned a Ph.D. from the University of Minnesota in 1934.


Career

After completing her Ph.D., Potter moved to Chicago. She was a pathology instructor in the obstetrics and gynecology department at the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
. Potter stayed at the university until her retirement. The school was affiliated with the
Chicago Lying-in Hospital The University of Chicago Medical Center, branded as UChicago Medicine, is a nationally ranked academic medical center located in Hyde Park on the South Side of Chicago. It is the flagship campus for The University of Chicago Medicine system and ...
, where Potter served as a pathologist. When a Chicago health department administrator began to consider the causes of infant mortality in the city, he decided to require autopsies in order for parents to obtain burial permits. In a period of more than 30 years, Potter performed more than 10,000 autopsies on infants. In 1940, Potter co-wrote ''Fetal and Neonatal Death'' with her department chair, Fred Lyman Adair; the pair analyzed the causes of death of more than 500 infants who had died in the 1930s. They found that hypoxia and
intracranial hemorrhage Intracranial hemorrhage (ICH) refers to any form of Hemorrhage, bleeding Internal bleeding, within the Human skull, skull. It can result from trauma, vascular abnormalities, hypertension, or other medical conditions. ICH is broadly categorized ...
, which were associated with long labors and difficult deliveries, were two leading causes of death. As she gained more experience with autopsies, Potter felt that identifying abnormalities in individual infants was only a small part of her work. She said that a larger goal was to correlate the findings of specific infants with those of groups of other infants, integrating physical findings with other potential etiologic factors to identify patterns and causes of infant death. Potter became well known for her work establishing
Rh disease Rh disease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the fetus and newborn (HDFN). The term "Rh disease" is commonly used to refer to HDFN due to a ...
as an important cause of infant death. She also published a 1946 paper that tied
renal agenesis Renal agenesis is a medical condition in which one (unilateral) or both (bilateral) fetal kidneys fail to develop. Unilateral and bilateral renal agenesis in humans, mice and zebra fish has been linked to mutations in the gene GREB1L. It has also ...
to specific facial findings in a group of 20 babies. Several years later, it was established that bilateral renal agenesis resulted in
oligohydramnios Oligohydramnios is a medical condition in pregnancy characterized by a deficiency of amniotic fluid, the fluid that surrounds the fetus in the abdomen, in the amniotic sac. The limiting case is anhydramnios, where there is a complete absence of ...
, and that the low levels of amniotic fluid caused fetal compression and the observed facial features. The process became known as
Potter sequence Potter sequence is the atypical physical appearance of a baby due to oligohydramnios experienced when in the uterus. It includes clubbed feet, pulmonary hypoplasia and cranial anomalies related to the oligohydramnios. Oligohydramnios is the decr ...
. Potter received an honorary doctorate from the
University of Brazil The Federal University of Rio de Janeiro (, UFRJ) is a public research university in Rio de Janeiro, Brazil. It is the largest federal university in the country and is one of the Brazilian centers of excellence in teaching and research. Brazil's ...
; she had served for a year as a guest lecturer there. The
University of South Florida The University of South Florida (USF) is a Public university, public research university with its main campus located in Tampa, Florida, Tampa, Florida, United States, and other campuses in St. Petersburg, Florida, St. Petersburg and Sarasota, ...
later awarded her an honorary Doctor of Science.


Personal life

In the summer of 1944, Potter married architectural sculptor Alvin Meyer, who had one daughter. Meyer was the sculpture department director for the architectural firm
Holabird & Root The architectural firm now known as Holabird & Root was founded in Chicago in 1880. Over the years, the firm has changed its name several times and adapted to the architectural style then current — from Chicago School to Art Deco to Moder ...
, and his work was featured on the
Chicago Board of Trade Building The Chicago Board of Trade Building is a 44-story, Art Deco skyscraper located in the Chicago Loop, standing at the foot of the LaSalle Street canyon. Built in 1930 for the Chicago Board of Trade (CBOT), it has served as the primary trading v ...
, which had been completed in 1930. Meyer served as the illustrator for one of Potter's books, ''Fundamentals of Human Reproduction'' (1948). Potter retired in the mid-1960s and moved to
Fort Myers, Florida Fort Myers (or Ft. Myers) is a city in and the county seat of Lee County, Florida, United States. As of the 2020 United States census, 2020 census, the population was 86,395; it was estimated to have grown to 95,949 in 2022, making it the List o ...
, with Meyer. Meyer died in 1976. Shortly thereafter, Potter married Frank Deats, an architectural coordinator and watercolorist who had retired to Fort Myers several years earlier. Deats, who was the godson of inventor
J. Frank Duryea James Frank Duryea (October 8, 1869 – February 15, 1967) was an American engineer and inventor who, with his brother Charles Duryea, Charles (1861–1938), invented the first American gasoline-powered automobile. Biography The brothers were bo ...
, helped in designing the
National Gallery of Art The National Gallery of Art is an art museum in Washington, D.C., United States, located on the National Mall, between 3rd and 9th Streets, at Constitution Avenue NW. Open to the public and free of charge, the museum was privately established in ...
and expanding the
National Archives Building The National Archives Building, known informally as Archives I, is the headquarters of the United States National Archives and Records Administration. It is located north of the National Mall at 700 Pennsylvania Avenue (Washington, D.C.), Penn ...
. Deats died in 1983.


Later life

After her retirement from medicine, Potter became interested in
horticulture Horticulture (from ) is the art and science of growing fruits, vegetables, flowers, trees, shrubs and ornamental plants. Horticulture is commonly associated with the more professional and technical aspects of plant cultivation on a smaller and mo ...
, especially the cultivation of indoor plants. Potter grew
bromeliads The Bromeliaceae (the bromeliads) are a family of monocot flowering plants of about 80 genera and 3700 known species, native mainly to the tropical Americas, with several species found in the American subtropics and one in tropical west Africa, ...
, and she donated 122 cultivars to the University of Minnesota in 1980 to establish the Meyer-Deats Conservatory at the school's arboretum. The conservatory was named in honor of Potter's husbands.Dr. Edith Potter
. ''Journal of the Bromeliad Society'' 31 (2):81. March–April 1981.
Potter was diagnosed with
colon cancer Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel ...
late in life and she died while on a 1993 cruise in the Caribbean. An endowed professorship at
Florida Gulf Coast University Florida Gulf Coast University (FGCU) is a public university in Lee County, Florida, near Fort Myers. It is part of the State University System of Florida and is its second-youngest member. The university was established on May 3, 1991, and is acc ...
was established in Potter's name. She is also honored by the
American Congress of Obstetricians and Gynecologists The American College of Obstetricians and Gynecologists (ACOG) is a professional association of physicians specializing in obstetrics and gynecology in the United States. Several Latin American countries are also represented within Districts of ...
with a lectureship in her name.


Publications

*''Fetal and neonatal death'' (1939, with Fred L. Adair) *''Rh, its relation to congenital hemolytic disease & to intragroup transfusion reactions'' (1947) *''Fundamentals of Human Reproduction'' (1948) *''Pathology of the Fetus and Infant'' (1953)


References

{{DEFAULTSORT:Potter, Edith American pathologists 1901 births 1993 deaths Deaths from colorectal cancer People from Clinton, Iowa University of Minnesota Medical School alumni University of Chicago faculty