The Clostridiaceae are a family of the
bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
l class
Clostridia, and contain the genus ''
Clostridium''.
The family Clostridiaceae (scientific name) defined by the taxonomic outline of '' Bergey's Manual of Systematic Bacteriology '' contains as its core the genus ''
Clostridium'' (''sensu stricto''), as well as ''
Acetivibrio'', ''
Acidaminobacter'', ''
Alkaliphilus'', ''
Anaerobacter'', ''
Caloramator'', ''
Caloranaerobacter'', ''
Coprobacillus'', ''
Dorea'', ''
Natronincola'', ''
Oxobacter'', ''
Sarcina'', ''
Sporobacter'', ''
Thermobrachium'', ''
Thermohalobacter'', and ''
Tindallia''. The previous inclusion of these additional genera (as seen on the right) in a family Clostridiaceae is based for the most part because the
type species of these genera are in many cases phylogenetically related to misclassified species of the genus ''Clostridium''. However, with the exception of ''Anaerobacter'', ''Caloramator'', ''Oxobacter'', ''Sarcina'', and ''Thermobrachium'', these genera fall outside the radiation of what can be considered the true family Clostridiaceae and are now regarded as belonging to other families within the low G + C, Gram-positive phylum.
This misclassification is the result of well-known problems of the current taxonomic structure of the
traditional genus ''Clostridium''. The phylogenetic analysis of Collins (1994) was the first large-scale comparison of 16S rRNA gene sequences of species of the genus ''Clostridium'' and related taxa. The fact that the species of the genus ''Clostridium'' did not form a monophyletic group has been shown in a number of studies in which small groups of ''Clostridium'' species had been compared as far back as 1981. The comparative study of Collins (1994) and subsequent studies can be used to conclude that more than half of the species currently assigned to this genus are in fact not closely related to the type species, ''
C. butyricum'', and from a phylogenetic standpoint should not be included in a newly defined genus ''Clostridium''.
This extensive genetic diversity of the genus ''Clostridium'' had been shown using 23S rRNA:DNA hybridization studies back in 1975 by Johnson and Francis, but the 16S rRNA gene sequence approach revealed the actual phylogenetic relationships between the species of this genus and other genera.
The genus ''Clostridium'' currently comprises 152 validly described species in nomenclature.
www.bacterio.net
/ref> However, on the basis of 16S rRNA gene sequence analyses, only 73 of these fall within the radiation of the type species of the genus ''Clostridium''.
Subdivisions
The polyphyletic family Clostridiaceae comprises the following:
Phylogeny
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)
See also
* List of bacteria genera
* List of bacterial orders
References
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