] ''Omphalotus subilludens'' is a fungus species in the genus ''

Omphalotus ''Omphalotus'' is a genus of basidiomycete mushroom, in the family Marasmiaceae, formally circumscribed by Victor Fayod in 1889. Members have the traditional cap and stem structure. They are saprobic, and fruit in clumps on the ground, ad ...

''. The type collection was found by

Murrill Murrill is a surname. Notable people with the surname include: * Herbert Murrill (1909–1952), English musician, composer, and organist * William Murrill (1869–1957), American mycologist See also * Murrell (disambiguation) * Murrills Murrills ...

on July 26, 1944, in

Gainesville, Florida Gainesville is the county seat of Alachua County, Florida, and the largest city in North Central Florida, with a population of 141,085 in 2020. It is the principal city of the Gainesville metropolitan area, which had a population of 339,247 in ...

. It has also been recorded from

Texas Texas (, ; Spanish language, Spanish: ''Texas'', ''Tejas'') is a state in the South Central United States, South Central region of the United States. At 268,596 square miles (695,662 km2), and with more than 29.1 million residents in 2 ...

Atromentin Atromentin is a natural chemical compound found in Agaricomycetes fungi in the orders Agaricales and Thelephorales. It can also be prepared by laboratory synthesis. Chemically, it is a polyphenol and a benzoquinone. Occurrences Atromentin has ...

and thelephoric acid are chemical compounds found in cultures of ''O. subilludens''. Atromentin is an effective

anticoagulant Anticoagulants, commonly known as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time. Some of them occur naturally in blood-eating animals such as leeches and mosquitoes, where t ...

, and similar in

biological activity In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or ...

to the well-known anticoagulant

heparin Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Since heparins depend on the activity of antithrombin, they are considered anticoagulants. Specifically it is also used in the trea ...

. Atromentin also possesses antibacterial activity, inhibiting the enzyme

enoyl-acyl carrier protein reductase Enoyl-acyl carrier protein reductase (or ENR) (), is a key enzyme of the type II fatty acid synthesis (FAS) system. ENR is an attractive target for narrow-spectrum antibacterial drug discovery because of its essential role in metabolism and its seq ...

(essential for the biosynthesis of

fatty acid In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, ...

s) in the bacteria ''

Streptococcus pneumoniae ''Streptococcus pneumoniae'', or pneumococcus, is a Gram-positive, spherical bacteria, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), aerotolerant anaerobic member of the genus Streptococcus. They a ...

''. It also produces illudoids.Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922,

References

External links

''Omphalotus subilludens'' on www.mycobank.org
Fungi described in 1982 subilludens Taxa named by William Alphonso Murrill {{Marasmiaceae-stub