Castoreum is a yellowish

exudate An exudate is a fluid released by an organism through pores or a wound, a process known as exuding or exudation. ''Exudate'' is derived from ''exude'' 'to ooze' from Latin language, Latin 'to (ooze out) sweat' (' 'out' and ' 'to sweat'). Medi ...

from the castor sacs of mature

beaver Beavers (genus ''Castor'') are large, semiaquatic rodents of the Northern Hemisphere. There are two existing species: the North American beaver (''Castor canadensis'') and the Eurasian beaver (''C. fiber''). Beavers are the second-large ...

s used in combination with urine to

scent mark In ethology, territory is the sociographical area that an animal consistently defends against conspecific competition (or, occasionally, against animals of other species) using agonistic behaviors or (less commonly) real physical aggression. ...

their territory. Both beaver sexes have a pair of castor sacs and a pair of anal glands, located in two cavities under the skin between the pelvis and the base of the tail. The castor sacs are not true glands (

endocrine The endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs. In vertebrates, the hypotha ...

or exocrine) on a cellular level, hence references to these structures as

preputial glands Preputial glands are exocrine glands in the prepuce in front of the penis. They occur in many mammals, including canids, mice, ferrets, rhinoceroses, and even-toed ungulates and produce pheromones. The preputial glands of female animals are so ...

, castor glands, or

scent glands Scent gland are exocrine glands found in most mammals. They produce semi-viscous secretions which contain pheromones and other semiochemical compounds. These odor-messengers indicate information such as status, territorial marking, mood, and ...

are misnomers. It is extracted with alcohol from the dried and crushed castor sacs for use as a

tincture A tincture is typically an extract of plant or animal material dissolved in ethanol (ethyl alcohol). Solvent concentrations of 25–60% are common, but may run as high as 90%.Groot Handboek Geneeskrachtige Planten by Geert Verhelst In chemistr ...

in some

perfume Perfume (, ) is a mixture of fragrance, fragrant essential oils or aroma compounds (fragrances), Fixative (perfumery), fixatives and solvents, usually in liquid form, used to give the human body, animals, food, objects, and living-spaces an agre ...

sInternational Perfume Museum, Grasse, France, Website: and, rarely, as a

food additive Food additives are substances added to food to preserve flavor or enhance taste, appearance, or other sensory qualities. Some additives, such as vinegar ( pickling), salt ( salting), smoke ( smoking) and sugar ( crystallization), have been used f ...

Chemical composition

At least 24 compounds are known constituents of beaver castoreum. Several of these have pheromonal activity, of which the

phenol Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile and can catch fire. The molecule consists of a phenyl group () ...

s 4-ethylphenol and

catechol Catechol ( or ), also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula . It is the ''ortho'' isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amounts. It ...

and the

ketone In organic chemistry, a ketone is an organic compound with the structure , where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group (a carbon-oxygen double bond C=O). The simplest ketone is acetone ( ...

s acetophenone and 3-hydroxyacetophenone are strongest. Five additional compounds elicit a weaker response: 4-methylcatechol,

4-methoxyacetophenone Acetanisole is an aromatic chemical compound with an aroma described as sweet, fruity, nutty, and similar to vanilla. In addition acetanisole can sometimes smell like butter or caramel. Its chemical names are based on considering the structure as ...

, 5-methoxysalicylic acid, salicylaldehyde, and 3-hydroxybenzoic acid. There are also oxygen-containing

monoterpene Monoterpenes are a class of terpenes that consist of two isoprene units and have the molecular formula C10H16. Monoterpenes may be linear (acyclic) or contain rings (monocyclic and bicyclic). Modified terpenes, such as those containing oxygen func ...

s such as 6-methyl-1-heptanol, 4,6-dimethyl-1-heptanol, isopinocamphone, pinocamphone, and two

linalool Linalool () refers to two enantiomers of a naturally occurring terpene alcohol found in many flowers and spice plants. Together with geraniol, nerol, and citronellol, linalool is one of the rose alcohols. Linalool has multiple commercial app ...

oxides and their

acetate An acetate is a salt formed by the combination of acetic acid with a base (e.g. alkaline, earthy, metallic, nonmetallic, or radical base). "Acetate" also describes the conjugate base or ion (specifically, the negatively charged ion called ...

s. Other compounds are:

benzoic acid Benzoic acid () is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. The benzoyl group is often abbreviated "Bz" (not to be confused with "Bn," which ...

benzyl alcohol Benzyl alcohol (also known as α-cresol) is an aromatic alcohol with the formula C6H5CH2OH. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Benzyl a ...

, borneol, ''o''-cresol, 4-(4'-hydroxyphenyl)-2-butanone,

hydroquinone Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a ''para' ...

, and

. All those compounds are gathered from plant food. It also contains nupharamine alkaloids, castoramine, and ''cis''- cyclohexane-1,2-diol.

Uses

In perfume

In perfumery, the term ''castoreum'' refers to the resinoid extract resulting from the dried and alcohol tinctured beaver castor. The dried beaver castor sacs are generally aged for two or more years to mellow. Castoreum is largely used for its

note Note, notes, or NOTE may refer to: Music and entertainment * Musical note, a pitched sound (or a symbol for a sound) in music * ''Notes'' (album), a 1987 album by Paul Bley and Paul Motian * ''Notes'', a common (yet unofficial) shortened versi ...

suggesting leather, typically compounded with other ingredients, including top, middle, and base notes. Some classic perfumes incorporating castoreum are Emeraude,

Chanel Chanel ( , ) is a French luxury fashion house founded in 1910 by Coco Chanel in Paris. It is privately owned by French brothers, Alain and Gérard Wertheimer, through the holding company Chanel Limited, established in 2018 and headquarte ...

Antaeus, Cuir de Russie, Magie Noire, Lancôme Caractère, Hechter Madame, Givenchy III, Shalimar, and many "leather" themed compositions.

In food

In the

United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...

, the

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...

lists castoreum extract as a

generally recognized as safe Generally recognized as safe (GRAS) is a United States Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts under the conditions of its intended use. An ingredient with a GRAS d ...

(GRAS)

. In 1965, the Flavor and Extract Manufacturers Association's GRAS program (FEMA 2261 and 2262) added castoreum extract and castoreum liquid. Historically, compounds isolated from castoreum were used in strawberry and raspberry flavorings and vanilla substitutes, but at present, the annual industry consumption is very low, around , whereas

vanillin Vanillin is an organic compound with the molecular formula . It is a phenolic aldehyde. Its functional groups include aldehyde, hydroxyl, and ether. It is the primary component of the ethanolic extract of the vanilla bean. Synthetic vanillin ...

is over annually. Castoreum has been traditionally used in

Sweden Sweden, formally the Kingdom of Sweden, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, and Finland to the east. At , Sweden is the largest Nordic count ...

for flavoring a variety of

schnapps Schnapps ( or ) or schnaps is a type of alcoholic beverage that may take several forms, including distilled fruit brandies, herbal liqueurs, infusions, and "flavored liqueurs" made by adding fruit syrups, spices, or artificial flavorings to ...

commonly referred to as ().

Other

Castoreum was also considered as an ingredient for the flavor and odor of

cigarette A cigarette is a narrow cylinder containing a combustible material, typically tobacco, that is rolled into Rolling paper, thin paper for smoking. The cigarette is ignited at one end, causing it to smolder; the resulting smoke is orally inhale ...

s.
United States Patent Application US20140123991A1
"Examples of the hydrophobic flavorant include ... castoreum" Medieval

beekeeper A beekeeper is a person who keeps honey bees, a profession known as beekeeping. The term beekeeper refers to a person who keeps honey bees in beehives, boxes, or other receptacles. The beekeeper does not control the creatures. The beekeeper ow ...

s used castoreum to increase

honey Honey is a sweet and viscous substance made by several species of bees, the best-known of which are honey bees. Honey is made and stored to nourish bee colonies. Bees produce honey by gathering and then refining the sugary secretions of pl ...

production.''The Beaver: Its Life and Impact''. Dietland Muller-Schwarze, 2003, page 43
book at Google Books

Related animal products

* Taxea, a secretion of the

badger Badgers are medium-sized short-legged omnivores in the superfamily Musteloidea. Badgers are a polyphyletic rather than a natural taxonomic grouping, being united by their squat bodies and adaptions for fossorial activity rather than by the ...

's subcaudal glands comparable in its medicinal use to the better-known castoreum * Hyraceum, the petrified and rock-like excrement composed of urine and feces excreted by the Cape hyrax (''Procavia capensis''), and a sought-after material that has been used in traditional South African medicine and perfumery

References

External links

The International Perfume Museum: Castoreum
{{Ancient anaesthesia-footer Animal glandular products Beavers