D01A Antifungals for topical use

D01AA
Antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, ...
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Nystatin Nystatin, sold under the brandname Mycostatin among others, is an antifungal medication. It is used to treat '' Candida'' infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. It may also be ...

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Natamycin Natamycin, also known as pimaricin, is an antifungal medication used to treat fungal infections around the eye. This includes infections of the eyelids, conjunctiva, and cornea. It is used as eyedrops. Natamycin is also used in the food indust ...

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Hachimycin Hachimycin, also known as trichomycin, is a polyene macrolide antibiotic, antiprotozoal, and antifungal derived from streptomyces ''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over ...

:D01AA04 Pecilocin :D01AA06

Mepartricin Mepartricin is a macrolide polyene compound that is useful for urethra, prostate, and bladder function. It has been studied for use in treating chronic pelvic pain syndrome and benign prostatic hyperplasia. Pharmacodynamics Mepartricin is an ...

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Pyrrolnitrin Pyrrolnitrin is an antifungal antibiotic. '' Pseudomonas pyrrocinia'' and other ''Pseudomonas'' species produce pyrrolnitrin from tryptophan as secondary metabolite. The fungicides fenpiclonil and fludioxonil Fludioxonil is a non-systemic fungic ...

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Griseofulvin Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). This includes fungal infections of the nails and scalp, as well as the skin when antifungal creams have not worked. It is taken by mouth. ...

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D01AC
Imidazole Imidazole (ImH) is an organic compound with the formula C3N2H4. It is a white or colourless solid that is soluble in water, producing a mildly alkaline solution. In chemistry, it is an aromatic heterocycle, classified as a diazole, and has non ...
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triazole A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C2H3N3. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within th ...
derivatives

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Clotrimazole Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock ...

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Miconazole Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. It is used for ring worm of the body, groin (jock itch), and ...

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Econazole Econazole is an antifungal medication of the imidazole class. It was patented in 1968, and approved for medical use in 1974. Medical uses Econazole is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicol ...

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Clomidazole Chlormidazole ( INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug. Synthesis See also * Clemizole Clemizole is an H1 antagonist. Synthesis Benzimidazoles substituted with an alkylamine at position 2 ha ...

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Isoconazole Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. For foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole. Isoconazole nitrate may be used in combination with corticosteroid diflucor ...

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Tiabendazole Tiabendazole (INN, BAN), also known as thiabendazole ( AAN, USAN) or TBZ and the trade names Mintezol, Tresaderm, and Arbotect, is a preservative, an antifungal agent, and an antiparasitic agent. Uses Preservative Tiabendazole is used prima ...

:D01AC07 Tioconazole :D01AC08

Ketoconazole Ketoconazole, sold under the brand name Nizoral among others, is an antiandrogen and antifungal medication used to treat a number of fungal infections. Applied to the skin it is used for fungal skin infections such as tinea, cutaneous can ...

:D01AC09 Sulconazole :D01AC10

Bifonazole Bifonazole (trade name Canespor among others) is an imidazole antifungal drug used in form of ointments. It was patented in 1974 and approved for medical use in 1983. There are also combinations with carbamide for the treatment of onychomycosi ...

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Oxiconazole Oxiconazole (trade names Oxistat in the US, Oxizole in Canada) is an antifungal medication typically administered in a cream or lotion to treat skin infections, such as athlete's foot, jock itch and ringworm. It can also be prescribed to treat th ...

:D01AC12 Fenticonazole :D01AC13 Omoconazole :D01AC14 Sertaconazole :D01AC15

Fluconazole Fluconazole is an antifungal medication used for a number of fungal infections. This includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis versicolor. It is also used to prev ...

:D01AC16 Flutrimazole :D01AC17 Eberconazole :D01AC18 Luliconazole :D01AC19 Efinaconazole :D01AC20 Imidazoles/triazoles in combination with

corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are in ...

s :D01AC21 Neticonazole :D01AC22 Lanoconazole :D01AC52 Miconazole, combinations :D01AC60 Bifonazole, combinations :QD01AC90 Enilconazole

D01AE Other antifungals for topical use

:D01AE01 Bromochlorosalicylanilide :D01AE02

Methylrosaniline Crystal violet or gentian violet, also known as methyl violet 10B or hexamethyl pararosaniline chloride, is a triarylmethane dye used as a histological stain and in Gram's method of classifying bacteria. Crystal violet has antibacterial, antif ...

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Tribromometacresol Tribromometacresol is an antifungal medication. This compound belongs to the class of organic compounds known as meta cresols, containing a meta cresol moiety which consists of a benzene ring bearing a methyl In organic chemistry, a methyl gr ...

:D01AE04 Undecylenic acid :D01AE05

Polynoxylin Polynoxylin (trade name Anaflex in Egypt) is an antiseptic for local treatment of the skin and the mouth. It is a formaldehyde releasing antimicrobial polymer A polymer (; Greek '' poly-'', "many" + ''-mer'', "part") is a substance or ...

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2-(4-chlorphenoxy)-ethanol Chlorophetanol is an antifungal An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious ...

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Chlorphenesin Chlorphenesin carbamate (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms. Chlorphenesin is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such ...

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Ticlatone Ticlatone (trade name Landromil) is an antifungal. References Antifungals Benzothiazoles Chloroarenes Lactams Isothiazolidinones Benzoisothiazolinones Preservatives {{dermatologic-drug-stub ...

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Sulbentine Sulbentine (or dibenzthione) is an antifungal. References Antifungals Sulfur heterocycles Dithiocarbamates Nitrogen heterocycles Heterocyclic compounds with 1 ring {{Dermatologic-drug-stub ...

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Ethyl hydroxybenzoate Ethylparaben (ethyl ''para''-hydroxybenzoate) is the ethyl ester of ''p''-hydroxybenzoic acid. Its formula is HO-C6H4-CO-O-CH2CH3. It is a member of the class of compounds known as parabens. It is used as an antifungal preservative. As a food ...

:D01AE11 Haloprogin :D01AE12

Salicylic acid Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone, and has been listed by the EPA Toxic Substanc ...

:D01AE13 Selenium sulfide :D01AE14

Ciclopirox Ciclopirox (sometimes known by the abbreviation CPX) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against tinea versicolor. It is sold under many brand names worldwide.Drugs.coInte ...

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Terbinafine Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. It is either taken by mouth or appli ...

:D01AE16 Amorolfine :D01AE17 Dimazole :D01AE18

Tolnaftate Tolnaftate (INN) is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, liquid, and liquid aerosol. Tolnaftate is used to treat f ...

:D01AE19 Tolciclate :D01AE20 Combinations :D01AE21

Flucytosine Flucytosine, also known as 5-fluorocytosine (5-FC), is an antifungal medication. It is specifically used, together with amphotericin B, for serious ''Candida'' infections and cryptococcosis. It may be used by itself or with other antifungals fo ...

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Naftifine Naftifine hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (topical fungal infections). Naftifine was invented at the Sandoz Rese ...

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Butenafine Butenafine, sold under the brand names Lotrimin Ultra, Mentax, and Butop ( India), is a synthetic benzylamine antifungal. It is structurally related to synthetic allylamine antifungals such as terbinafine. Medical uses Butenafine is indicate ...

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Tavaborole Tavaborole, sold under the brand name Kerydin, is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed with a complete clearance rate of 6-7% and partial clearance rate of 23-24% in ind ...

:D01AE25 Liranaftate :D01AE54 Undecylenic acid, combinations :QD01AE91

Bronopol Bronopol (INN; chemical name 2-bromo-2-nitropropane-1,3-diol) is an organic compound that is used as an antimicrobial. It is a white solid although commercial samples appear yellow. The first reported synthesis of bronopol was in 1897. Bronopol ...

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D01B Antifungals for systemic use

D01BA Antifungals for systemic use

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Fosravuconazole Fosravuconazole (trade name Nailin) is a triazole antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole. The Drugs for Neglected Disea ...

References