C04A Peripheral
vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction ...
s
C04AA
2-amino-1-phenylethanol
Phenylethanolamine (sometimes abbreviated PEOH), or β-hydroxyphenethylamine, is a trace amine with a structure similar to those of other trace phenethylamines as well as the catecholamine neurotransmitters dopamine, norepinephrine, and epinephri ...
derivatives
:C04AA01
Isoxsuprine
Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a β2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth musc ...
:C04AA02
Buphenine
:C04AA31
Bamethan
C04AB
Imidazoline
Imidazoline is a class of heterocycles formally derived from imidazoles by the reduction of one of the two double bonds. Three isomers are known, 2-imidazolines, 3-imidazolines, and 4-imidazolines. The 2- and 3-imidazolines contain an imine
In ...
derivatives
:C04AB01
Phentolamine
Phentolamine, sold under the brand name Regitine among others, is a reversible nonselective α-adrenergic antagonist.
Mechanism
Its primary action is vasodilation due to α1 blockade.
Non-selective α-blockers can cause a much more pronounced r ...
:C04AB02
Tolazoline
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with sodium nitroprusside) su ...
C04AC
Nicotinic acid
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variet ...
and derivatives
:C04AC01
Nicotinic acid
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variet ...
:C04AC02
Nicotinyl alcohol (pyridylcarbinol)
:C04AC03
Inositol nicotinate
Inositol nicotinate, also called inositol hexanicotinate, is marketed in the United States as a "no-flush niacin" dietary supplement. Flushing, in physiology, essentially means that epidermal tissues have become reddened, such as when the skin ...
:C04AC07
Ciclonicate
Ciclonicate is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is t ...
C04AD
Purine
Purine is a heterocyclic aromatic organic compound that consists of two rings ( pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives its name to the wider class of molecules, purines, which include substituted purin ...
derivatives
:C04AD01
Pentifylline
Pentifylline (marketed as Cosaldon) is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller art ...
:C04AD02
Xantinol nicotinate
Xanthinol is a drug prepared from theophylline used as a vasodilator. It is most often used as the salt with niacin
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. ...
:C04AD03
Pentoxifylline
Pentoxifylline, also known as oxpentifylline, is a xanthine derivative used as a drug to treat muscle pain in people with peripheral artery disease. It is generic and sold under many brand names worldwide.Drugs.codrugs.com international listing ...
:C04AD04
Etofylline nicotinate
Etofylline nicotinate is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The pr ...
:QC04AD90
Propentofylline
Propentofylline (HWA 285) is a xanthine derivative drug with purported neuroprotective effects.
Pharmacology
It is a phosphodiesterase inhibitor, and also acts as an adenosine reuptake inhibitor.
Uses
Propentofylline was studied as a possible tre ...
C04AE
Ergot
Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''.
The most prominent member of this group is '' Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that ca ...
alkaloids
:C04AE01
Ergoloid mesylates
Ergoloid mesylates ( USAN), co-dergocrine mesilate (BAN) or dihydroergotoxine mesylate, trade name Hydergine, is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alp ...
:C04AE02
Nicergoline
:C04AE04
Dihydroergocristine
Dihydroergocristine is an ergot alkaloid. Alongside dihydroergocornine and dihydroergocryptine
Dihydroergocryptine (DHEC), sold under the brand names Almirid and Cripar among others, is a dopamine agonist of the ergoline group that is used as ...
:C04AE51 Ergoloid mesylates, combinations
:C04AE54 Dihydroergocristine, combinations
C04AF
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
s
:C04AF01
Kallidinogenase Urinary kallikrein may refer to:
* Plasma kallikrein
Plasma kallikrein (, ''serum kallikrein'', ''kininogenin'', ''kallikrein I'', ''kallikrein II'', ''kininogenase'', ''kallikrein'', ''callicrein'', ''glumorin'', ''padreatin'', ''padutin'', ''ka ...
C04AX Other peripheral vasodilators
:C04AX01
Cyclandelate
:C04AX02
Phenoxybenzamine
Phenoxybenzamine (marketed under the trade names Dibenzyline and Dibenyline) is a non-selective, irreversible alpha blocker.
Uses
It is used in the treatment of hypertension, and specifically that caused by pheochromocytoma. It has a slower ons ...
:C04AX07
Vincamine
Vincamine is a monoterpenoid indole alkaloid found in the leaves of ''Vinca minor'' (lesser periwinkle), comprising about 25-65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids.
Uses
Vincamine is sold in Eu ...
:C04AX10
Moxisylyte
Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction
Erectile dysfunction (ED), also called impotence, is the type of sexual dysfunction in which the penis fails to become or stay erec ...
:C04AX11
Bencyclane
:C04AX17
Vinburnine
Vinburnine (or eburnamonine, ''Vincamone'') is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and small ...
:C04AX19
Sulcotidil
Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.
Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, ...
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Buflomedil
:C04AX21
Naftidrofuryl
Naftidrofuryl ( INN), also known as nafronyl or as the oxalate salt naftidrofuryl oxalate or nafronyl oxalate, is a vasodilator used in the management of peripheral and cerebral vascular disorders. It is also claimed to enhance cellular oxidati ...
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Butalamine
:C04AX24
Visnadine
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Cetiedil
Cetiedil is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the o ...
:C04AX27
Cinepazide
Cinepazide or cinepazide maleate (Kelinao or Anjieli in ChinaDrugs.coPage accessed Aug 3, 201520 Oct 201Sihuan Pharm – China's leading player in cardio-cerebral vascular drug – IPO Report) is a vasodilator used in China for the treatment of c ...
:C04AX28
Ifenprodil
:C04AX30
Azapetine
Azapetine is a vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the ...
:C04AX32
Fasudil
References
{{Peripheral vasodilators
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