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Methyltryptamine
Methyltryptamine (MT) may refer to: * ''N''-Methyltryptamine (NMT; monomethyltryptamine) * α-Methyltryptamine (AMT or αMT; Indopan) * 1-Methyltryptamine (1-Me-T; PAL-637) * 2-Methyltryptamine (2-Me-T) * 5-Methyltryptamine (5-Me-T; PAL-22) See also * Dimethyltryptamine * Ethyltryptamine * Trimethyltryptamine * Methylethyltryptamine Methylethyltryptamine (MET), also known as ''N''-methyl-''N''-ethyltryptamine (''N'',''N''-MET), is a serotonergic psychedelic of the tryptamine family. It is closely related to dimethyltryptamine (DMT) and to diethyltryptamine (DET). The drug ... * Methylserotonin {{Chemistry index Methyl compounds Tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Methyltryptamine
''N''-Methyltryptamine (NMT), also known as monomethyltryptamine, is a chemical compound of the tryptamine family and a naturally occurring compound found in the human body and certain plants. It is biosynthesized in humans from tryptamine by certain ''N''-methyltransferase enzymes, such as indolethylamine ''N''-methyltransferase. It is a known component in human urine. NMT is an alkaloid derived from L-tryptophan that has been found in the bark, shoots and leaves of several plant genera, including '' Virola'', ''Acacia'', '' Mimosa'', and '' Desmanthus''—often together with the related compounds ''N'',''N''-dimethyltryptamine (DMT) and 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT). NMT acts as a serotonin receptor agonist and serotonin releasing agent and is said to produce hallucinogenic effects in humans. Effects Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism. Per Roger W. Brimbl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trimethyltryptamine
Trimethyltryptamine (TMT) may refer to: * α,''N'',''N''-Trimethyltryptamine (α,''N'',''N''-TMT; α-methyl-DMT or ''N'',''N''-dimethyl-AMT) * 2,''N'',''N''-Trimethyltryptamine (2,''N'',''N''-TMT; 2-methyl-DMT) * 5,''N'',''N''-Trimethyltryptamine (5,''N'',''N''-TMT; 5-methyl-DMT) * 7,''N'',''N''-Trimethyltryptamine (7,''N'',''N''-TMT; 7-methyl-DMT) * 4-phosphoryloxy-''N'',''N'',''N''-trimethyltryptamine (4-PO-N,N,N-TMT) See also * Methyltryptamine * Dimethyltryptamine * Ethyltryptamine * Methylethyltryptamine * Trimethylserotonin Trimethylserotonin (TMS) may refer to: * Bufotenidine (''N'',''N'',''N''-trimethylserotonin) * 5-MeO-DMT 5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psy ... {{Chemistry index Methyl compounds Tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dimethyltryptamine (other)
Dimethyltryptamine (DMT) may refer to: * ''N'',''N''-Dimethyltryptamine (''N'',''N''-DMT) * 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT) * α,''N''-Dimethyltryptamine (α,''N''-DMT; ''N''-methyl-αMT; SK&F-7024, Ro 3–1715) * 4,α-Dimethyltryptamine (4,α-DMT; 4-methyl-AMT; MP-809) See also * Methyltryptamine * Ethyltryptamine * Trimethyltryptamine * Methylethyltryptamine Methylethyltryptamine (MET), also known as ''N''-methyl-''N''-ethyltryptamine (''N'',''N''-MET), is a serotonergic psychedelic of the tryptamine family. It is closely related to dimethyltryptamine (DMT) and to diethyltryptamine (DET). The drug ... * Dimethylserotonin {{Chemistry index Methyl compounds Tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-Methyltryptamine
2-Methyltryptamine (2-MT, 2-Me-T, or 2-methyl-T) is a serotonin receptor agonist of the substituted tryptamine, tryptamine family. It shows dramatically reduced activity at serotonin receptors compared to tryptamine and mixed effects in terms of head-twitch response, psychedelic-like effects in animals. Pharmacology 2-MT shows affinity (pharmacology), affinity (Ki) for the serotonin 5-HT1A receptor, 5-HT1A and 5-HT2A receptor, 5-HT2A receptors, with Ki values of 1,095nM and 7,774nM, respectively. These affinities were respectively 34-fold and 3.2-fold lower than those of tryptamine in the same study. It also acts as an agonist of the serotonin 5-HT1A and 5-HT2A receptors, with values of 12,534nM and 4,598nM, respectively. These receptor activation, activational potency (pharmacology), potencies were respectively 14-fold and 19-fold lower than those of tryptamine in the same study. It does not produce conditioned place preference (CPP), self-administration, or changes in locomoto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
5-Methyltryptamine
5-Methyltryptamine (5-MeT, 5-Me-T) is a non-selective serotonin receptor agonist and serotonin releasing agent of the tryptamine family that has been used in scientific research. It is related to other 5-substituted tryptamines such as serotonin (5-hydroxytryptamine; 5-HT) and 5-methoxytryptamine (5-MeO-T). The compound is also a positional isomer of ''N''-methyltryptamine (NMT). Pharmacology 5-MeT is known to act as a potent serotonin 5-HT2A receptor full agonist, with an of 6.00nM and an of 100%. In addition, it is known to be a ligand of the serotonin 5-HT1A and 5-HT2B receptors and an agonist of the serotonin 5-HT1D and 5-HT2C receptors. Similarly to tryptamine and 5-MeO-T, but in contrast to serotonin, 5-MeT shows very low potency as an agonist of the serotonin 5-HT3 receptor ( = 60,000nM). In addition to acting as an agonist of various serotonin receptors, 5-MeT is a monoamine releasing agent (MRA), with high selectivity for induction of serotonin release over i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-Methyltryptamine
1-Methyltryptamine (1-methyl-T, 1-MT or 1-Me-T; code name PAL-637) is a serotonin receptor agonist and monoamine releasing agent of the substituted tryptamine, tryptamine family. It is the 1-methyl group, methyl chemical derivative, derivative of tryptamine (T; PAL-235). The drug is known to act as a serotonin 5-HT2A receptor, 5-HT2A receptor agonist (Ki = 473nM; = 209–4,560nM; = 55–99%), as a serotonin releasing agent ( = 53.1nM), and to be inactive in inducing the release of norepinephrine and dopamine ( = >10,000nM). Its activities at other serotonin receptors were not reported. 1-Methyltryptamine shows dramatically reduced affinity (pharmacology), affinity and receptor activation, activational potency (pharmacology), potency as well as reduced intrinsic activity, efficacy at the serotonin 5-HT2A receptor compared to tryptamine (which showed Ki = 13.1nM; = 7.36–99nM; = 101–104%). It also shows slightly reduced potency as a serotonin releasing agent and abolished act ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethyltryptamine
Ethyltryptamine (ET) may refer to: * α-Ethyltryptamine (AET or αET; Monase) * ''N''-Ethyltryptamine (NET) See also * Methyltryptamine * Dimethyltryptamine * Trimethyltryptamine * Methylethyltryptamine Methylethyltryptamine (MET), also known as ''N''-methyl-''N''-ethyltryptamine (''N'',''N''-MET), is a serotonergic psychedelic of the tryptamine family. It is closely related to dimethyltryptamine (DMT) and to diethyltryptamine (DET). The drug ... * Methylserotonin {{Chemistry index Ethyl compounds Tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylethyltryptamine (other)
Methylethyltryptamine (abbreviated as MET) may refer to: * ''N''-Methyl-''N''-ethyltryptamine (MET or ''N'',''N''-MET) * 4-Methyl-α-ethyltryptamine (4-Me-αET or 7-Me-AET) * 7-Methyl-α-ethyltryptamine (7-Me-αET or 7-Me-AET) See also * Methyltryptamine * Dimethyltryptamine * Ethyltryptamine * Trimethyltryptamine Trimethyltryptamine (TMT) may refer to: * α,''N'',''N''-Trimethyltryptamine (α,''N'',''N''-TMT; α-methyl-DMT or ''N'',''N''-dimethyl-AMT) * 2,''N'',''N''-Trimethyltryptamine (2,''N'',''N''-TMT; 2-methyl-DMT) * 5,''N'',''N''-Trimethyltryptamin ... * Methylserotonin {{Chemistry index Ethyl compounds Methyl compounds Tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylserotonin
Methylserotonin, or methyl-5-hydroxytryptamine (methyl-5-HT), may refer to: * 5-Methoxytryptamine (5-MeO-T; ''O''-methylserotonin; ''O''-Me-5-HT) * 2-Methyl-5-hydroxytryptamine (2-Me-5-HT; 2-methylserotonin) * α-Methylserotonin (α-methyl-5-hydroxytryptamine; α-methyl-5-HT; α-Me-5-HT) * ''N''-Methylserotonin (NMS; ''N''-methyl-5-hydroxytryptamine; ''N''-Me-5-HT) See also * Dimethylserotonin * Trimethylserotonin * Tetramethylserotonin * Methyltryptamine Methyltryptamine (MT) may refer to: * ''N''-Methyltryptamine (NMT; monomethyltryptamine) * α-Methyltryptamine (AMT or αMT; Indopan) * 1-Methyltryptamine (1-Me-T; PAL-637) * 2-Methyltryptamine (2-Me-T) * 5-Methyltryptamine (5-Me-T; PAL-22) See ... {{Chemistry index 5-Hydroxytryptamines Methyl compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methyl Compounds
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula ). In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bonded to the rest of the molecule by a single covalent bond (), it can be found on its own in any of three forms: methanide anion (), methylium cation () or methyl radical (). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed. Methyl cation, anion, and radical Methyl cation The methylium cation () exists in the gas phase, but is otherwise not encountered. Some compounds are considered to be sources of the cation, and this simplification is used pervasively in organic chemistry. For exampl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
