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Diptericin
Diptericin is a 9 kDa antimicrobial peptide (AMP) of flies first isolated from the blowfly '' Phormia terranova''. It is primarily active against Gram-negative bacteria, disrupting bacterial membrane integrity. The structure of this protein includes a proline-rich domain with similarities to the AMPs drosocin, pyrrhocoricin, and abaecin, and a glycine-rich domain with similarity to attacin. Diptericin is an iconic readout of immune system activity in flies, used ubiquitously in studies of ''Drosophila'' immunity. Diptericin is named after the insect order Diptera. Structure and function Diptericins are found throughout Diptera, but are most extensively characterized in ''Drosophila'' fruit flies. The mature structures of diptericins are unknown, though previous efforts to synthesize Diptericin have suggested Diptericin in '' Protophormia terraenovae'' is one linear peptide. Yet ''Drosophila melanogaster's'' Diptericin B peptide is likely cleaved into two separate peptides. S ...
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Providencia Rettgeri
''Providencia rettgeri'' (commonly ''P. rettgeri''), is a Gram negative bacterium that is commonly found in both water and land environments. ''P. rettgeri'' is in the genus Providencia (bacterium), Providencia, along with ''Providencia stuartii'', ''Providencia alcalifaciens'', and ''Providencia rustigianii''. ''P. rettgeri'' can be incubated at 37 °C in nutrient agar or nutrient broth. It was first discovered in 1904 after a waterfowl epidemic. Strains of the species have also been isolated from nematodes of the genus ''Heterorhabditis''. ''Providencia rettgeri'' also found in marine environment. Biochemical characteristics of ''Providencia rettgeri'' S.I. Paul et al. (2021) isolated, characterized and identified salt tolerant ''Providencia rettgeri'' from Sponge, marine sponge (''Niphates erecta'') of the St. Martin's Island, Saint Martin's Island Area of the Bay of Bengal, Bangladesh. Colony, morphological, physiological, and biochemical characteristics of ''Providen ...
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Drosophila Testacea
''Drosophila testacea'' is a member of the ''testacea'' species group of ''Drosophila''. Testacea species are specialist fruit flies that breed on the fruiting bodies of mushrooms. ''Drosophila testacea'' can be found in temperate regions of Europe, extending to East Asia. ''Drosophila testacea'' and '' Drosophila orientacea'' can produce viable hybrids, though they are separated by geography and behavioural barriers. ''Drosophila testacea'' females will also readily mate with ''Drosophila neotestacea'' males, but viable hybrids are never produced. This hybrid inviability (see Haldane's rule)) may be due to selfish X chromosomes and co-evolved suppressors. Alternately, differences in sex pheromone (e.g. vaccenyl acetate) reception could underlie female readiness and male willingness to copulate. The antimicrobial peptide gene '' Diptericin B'' has been pseudogenized in ''D. testacea'' and likely its sister species, ''D. neotestacea''. This was due to a lack of ''Acetobacter'' ...
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Antimicrobial Peptide
Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antimicrobials which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators. Structure Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. Antimicrobial peptides ...
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Leucophenga Varia
''Leucophenga varia'' is a species of fly in the family Drosophilidae. It occurs in North America. Unlike other Drosophilidae, it feeds on mushrooms, which has impacted the evolution of the Diptericin Diptericin is a 9 kDa antimicrobial peptide (AMP) of flies first isolated from the blowfly '' Phormia terranova''. It is primarily active against Gram-negative bacteria, disrupting bacterial membrane integrity. The structure of this protein incl ... gene of its innate immune system. References External links * Drosophilidae Diptera of North America Insects described in 1849 Taxa named by Francis Walker (entomologist) Articles created by Qbugbot {{drosophilidae-stub ...
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Attacin
Attacin is a glycine-rich protein of about 20 kDa belonging to the group of antimicrobial peptides (AMP). It is active against Gram-negative bacteria. Attacin was first discovered in ''Hyalophora cecropia ''Hyalophora cecropia'', the cecropia moth, is North America's largest native moth. It is a member of the family Saturniidae, or giant silk moths. Females have been documented with a wingspan of or more. These moths can be found predominately ac ...'', but is widely conserved in different insects from butterflies to fruit flies. See also * Diptericin, a structurally related antimicrobial peptide References {{Reflist Insect immunity Antimicrobial peptides ...
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Antimicrobial Peptides
Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between Prokaryote, prokaryotic and eukaryota, eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antimicrobials which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators. Structure Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. A ...
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Ecology
Ecology () is the natural science of the relationships among living organisms and their Natural environment, environment. Ecology considers organisms at the individual, population, community (ecology), community, ecosystem, and biosphere levels. Ecology overlaps with the closely related sciences of biogeography, evolutionary biology, genetics, ethology, and natural history. Ecology is a branch of biology, and is the study of abundance (ecology), abundance, biomass (ecology), biomass, and distribution of organisms in the context of the environment. It encompasses life processes, interactions, and adaptations; movement of materials and energy through living communities; ecological succession, successional development of ecosystems; cooperation, competition, and predation within and between species; and patterns of biodiversity and its effect on ecosystem processes. Ecology has practical applications in fields such as conservation biology, wetland management, natural resource m ...
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Scaptomyza
''Scaptomyza'' is a genus of vinegar flies, insects in the family Drosophilidae. , there are 273 described species of ''Scaptomyza''. Of those, 148 are endemic to the Hawaiian archipelago. This genus is part of the species-rich lineage of Hawaiian Drosophilidae, and is the sister lineage to the endemic Hawaiian ''Drosophila''. The genus ''Scaptomyza'' is one of several nested within the paraphyletic genus ''Drosophila.'' Two hypotheses have been proposed to explain the geographical distribution of ''Scaptomyza.'' The "single Hawaiian origin" hypothesis suggests that the common ancestor of ''Scaptomyza'' and Hawaiian ''Drosophila'' colonized Hawaii once, followed by several migrations to the mainland within ''Scaptomyza''. Alternatively, the "multiple Hawaiian origins" hypothesis suggests that the current distribution is the result of multiple colonization events (once for Hawaiian ''Drosophila'' and multiple times in ''Scaptomyza''). One member of the genus in particular, '' S. ...
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Drosophila Guttifera
''Drosophila guttifera'' is a species of vinegar fly in the Drosophila quinaria species group. Like many quinaria group species, ''D. guttifera'' feeds on rotting mushrooms. In 2015, the genome of ''Drosophila guttifera'' was sequenced by the laboratory of Sean B. Carroll providing an answer on how different wing patterns emerge in this species, relying on genetic switches called enhancers that drive the polka-dot pattern on the wings of ''D. guttifera''. These enhancers are cis-regulatory elements, which can promote new wing patterns by modifying gene expression, rather than the actual protein being expressed. Further reading * Description of background on ''D. guttifera'' use in genetic studies in the Drosophila quinaria species group article. Gallery File:CompareWings2.tif, Wing comparisons in the Drosophila quinaria species group The ''Drosophila quinaria'' species group is a speciose lineage of mushroom-feeding flies studied for their specialist ecology, thei ...
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Mushroom-feeding Drosophila
Mushroom-feeding ''Drosophila'' (mycophagous ''Drosophila'') are a subset of ''Drosophila'' flies that have highly specific mushroom-breeding ecologies. Often these flies can tolerate toxic compounds from ''Amanita'' mushrooms. Species groups * ''Drosophila testacea'' species group * ''Drosophila quinaria'' species group * '' Drosophila bizonata'' species group * Some members of the ''Drosophila obscura'' species group Sequenced genomes or transcriptomes * '' Drosophila guttifera'' * ''Drosophila neotestacea ''Drosophila neotestacea'' is a member of the ''testacea'' species group of '' Drosophila''. Testacea species are specialist fruit flies that breed on the fruiting bodies of mushrooms. These flies will choose to breed on psychoactive mushrooms ...'' * '' Drosophila innubila'' * '' Drosophila falleni'' * '' Drosophila phalerata'' Gallery File: Dneo f3.tif , '' D. neotestacea'' ( Testacea species group) File: Dtestacea male 2-4.tif , '' D. testacea'' ( Testace ...
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Acetobacter
''Acetobacter'' is a genus of acetic acid bacteria. Acetic acid bacteria are characterized by the ability to convert ethanol to acetic acid in the presence of oxygen. Of these, the genus ''Acetobacter'' is distinguished by the ability to oxidize lactate and acetate into carbon dioxide and water. Bacteria of the genus ''Acetobacter'' have been isolated from industrial vinegar fermentation processes and are frequently used as fermentation starter cultures. History of research The acetic fermentation was demonstrated by Louis Pasteur, who discovered the first acetobacter - ''Acetobacter aceti'' - in 1864. In 1998, two strains of ''Acetobacter'' isolated from red wine and cider vinegar were named '' Acetobacter oboediens'' and '' Acetobacter pomorum''. In 2000, ''Acetobacter oboediens'' and '' Acetobacter intermedius'' were transferred to '' Gluconacetobacter'' on the basis of 16S rRNA sequencing. In 2002, '' Acetobacter cerevisiae'' and '' Acetobacter malorum'' were identif ...
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Convergent Evolution
Convergent evolution is the independent evolution of similar features in species of different periods or epochs in time. Convergent evolution creates analogous structures that have similar form or function but were not present in the last common ancestor of those groups. The cladistic term for the same phenomenon is Cladogram#Homoplasies, homoplasy. The recurrent evolution of flight is a classic example, as flying pterygota, insects, birds, pterosaurs, and bats have independently evolved the useful capacity of flight. Functionally similar features that have arisen through convergent evolution are ''analogous'', whereas ''homology (biology), homologous'' structures or traits have a common origin but can have dissimilar functions. Bird, bat, and pterosaur wings are analogous structures, but their forelimbs are homologous, sharing an ancestral state despite serving different functions. The opposite of convergence is divergent evolution, where related species evolve different trai ...
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