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Coriamyrtin
Coriamyrtin is a toxic γ-lactone naturally present in a multitude of plants. Natural occurrence Coriamyrtin can be found in '' Scurrula parasitica'', '' Coriaria microphylla'', ''Coriaria nepalensis'', and certain other plants. Toxicity Coriamyrtin is a convulsant. It appears to act via antagonism of GABAA receptors. Poisoning is usually from ingestion of parts of the plants containing it. A case of poisoning was able to be treated with repeated administration of diazepam, an anticonvulsant Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also used in the treatme .... References GABAA receptor antagonists Heterocyclic compounds with 4 rings Epoxides Spiro compounds Gamma-lactones Isopropenyl compounds Tertiary alcohols Plant toxins Convulsants {{Ether-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coriaria Microphylla
''Coriaria ruscifolia'' is a plant of the Coriariaceae family. It is native to Mexico, Central America, and South America. Description ''Coriaria ruscifolia'' is a deciduous shrub. It is poisonous except for the "fruit", which are actually petals. Uses In Ecuador, its fruits are reportedly eaten to produce an inebriated state. The eater is said to experience “sensations of soaring through the air”. The effects are said to be similar to those produced by '' Petunia violacea''. ''Coriaria ruscifolia'' grows in Mexico as well; it has been suggested that it was the Aztec inebriant known as tlacopétatl. In the Las Huaringas region, a lake plateau in the northern Peruvian Andes, the local healers (curanderos) refer to ''Coriaria ruscifolia'' as contra-alergica, “against allergies.” They use the herbage to prepare a bath additive that they use to wash patients suffering from allergic reactions. Toxicity The fruits contain catechol derivatives and probably several sesquiter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coriaria Nepalensis
''Coriaria nepalensis'' is a shrub of the genus '' Coriaria''. It grows in the foothills of the Himalayas. It blooms in spring and has bright yellow flowers and red fruits in summer. The plant is also known in English as masuri berry, tanner's tree, or mansur shrub. In Hindi it is known as masuri (), makola, or masurya (); and in Nepali as macchaino (). Description ''C. nepalensis'' is a shrub, growing around 1.5-2.5 metres tall. Flowers, yellow in colour, are in groups (inflorescences) and they are male or female but in the same plant. It blooms from February to May. Fruits are red to dark purple when mature. They resemble berries, but they are actually achenes protected by enlarged and colored petals. The fruits are produced from May to August, but they are inedible as their seeds are poisonous. The number of chromosomes the plant has is 40. ''C. nepalensis'' is toxic due to the presence of coriamyrtin. Distribution ''C. nepalensis'' grows on the southern slopes of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma-lactone
Lactones are cyclic carboxylic esters. They are derived from the corresponding hydroxycarboxylic acids by esterification. They can be saturated or unsaturated. Lactones are formed by lactonization, the intramolecular esterification of the corresponding hydroxycarboxylic acids. Nomenclature Greek prefixes in alphabetical order indicate ring size. Lactones are usually named according to the precursor acid molecule (''aceto'' = 2 carbon atoms, ''propio'' = 3, ''butyro'' = 4, ''valero'' = 5, ''capro'' = 6, etc.), with a ''-lactone'' suffix and a Greek letter prefix that specifies the number of carbon atoms in the heterocycle — that is, the distance between the relevant -OH and the -COOH groups along said backbone. The first carbon atom after the carbon in the -COOH group on the parent compound is labelled α, the second will be labeled β, and so forth. Therefore, the prefixes also indicate the size of the lactone ring: α-lactone = 3-membered ring, β-lactone = 4-membered, γ-l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
