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Variational Properties
In evolutionary biology, the variational properties of an organism are those properties relating to the production of variation among its offspring. In a broader sense variational properties include phenotypic plasticity. Wagner, G. P. and Altenberg, L. 1996. Complex adaptations and the evolution of evolvability. ''Evolution'' 50 (3): 967-976. Variational properties contrast with functional properties. While the functional properties of an organism determine is level of adaptedness to its environment, it is the variational properties of the organisms in a species that chiefly determine its evolvability and genetic robustness. Variational properties group together many classical and more recent concepts of evolutionary biology. It includes the classical concepts of pleiotropy, canalization, developmental constraints, developmental bias, morphological integration, developmental homeostasis and later concepts such as robustness, neutral networks, modularity Modularity is ...
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Lee Altenberg
Lee Altenberg is an American theoretical biologist. He is on the faculty of the Departments of Information and Computer Sciences and of Mathematics at the University of Hawaiʻi at Mānoa. He is best known for his work that helped establish the evolution of evolvability and modularity in the genotype–phenotype map as areas of investigation in evolutionary biology, for moving theoretical concepts between the fields of evolutionary biology and evolutionary computation, and for his mathematical unification and generalization of modifier gene models for the evolution of biological information transmission, putting under a single mathematical framework the evolution of mutation rates, recombination rates, sexual reproduction rates, and dispersal rates. Altenberg is an associate editor of the journal '' BioSystems'', and serves on the editorial boards of the journals '' Genetic Programming and Evolvable Machines'' and ''Artificial Life'', and on the IEEE Computational Intelligenc ...
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Günter P
Gunter or Günter may refer to: * Gunter rig, a type of sailing rig, especially in small boats * Gunter Annex, Alabama, a United States Air Force installation * Gunter, Texas, city in the United States * the former German name of the village of Gintro, in northern Poland People Surname * Archibald Clavering Gunter, his ''Home Publishing Company'' published Gunter's Magazine (1905–1907) * Chris Gunter (born 1989), Welsh footballer with Cardiff City, Tottenham Hotspur, Nottingham Forest and Reading * Cornell Gunter (1936–1990), American R&B singer, brother of Shirley Gunter * David Gunter (1933–2005), English footballer with Southampton, brother of Phil Gunter * Edmund Gunter (1581–1626), British mathematician and inventor, known for: ** Gunter's chain ** Gunter's rule * James Gunter (1745–1819), English confectioner, fruit grower and scientific gardener * Jen Gunter (born 1966), Canadian-American gynecologist & author * Gordon Gunter (1909–1998), American marin ...
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Adaptation
In biology, adaptation has three related meanings. Firstly, it is the dynamic evolutionary process of natural selection that fits organisms to their environment, enhancing their evolutionary fitness. Secondly, it is a state reached by the population during that process. Thirdly, it is a phenotypic trait or adaptive trait, with a functional role in each individual organism, that is maintained and has evolved through natural selection. Historically, adaptation has been described from the time of the ancient Greek philosophers such as Empedocles and Aristotle. In 18th and 19th-century natural theology, adaptation was taken as evidence for the existence of a deity. Charles Darwin and Alfred Russel Wallace proposed instead that it was explained by natural selection. Adaptation is related to biological fitness, which governs the rate of evolution as measured by changes in allele frequencies. Often, two or more species co-adapt and co-evolve as they develop adaptations tha ...
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Evolvability
Evolvability is defined as the capacity of a system for adaptive evolution. Evolvability is the ability of a population of organisms to not merely generate genetic diversity, but to generate '' adaptive'' genetic diversity, and thereby evolve through natural selection. In order for a biological organism to evolve by natural selection, there must be a certain minimum probability that new, heritable variants are beneficial. Random mutations, unless they occur in DNA sequences with no function, are expected to be mostly detrimental. Beneficial mutations are always rare, but if they are too rare, then adaptation cannot occur. Early failed efforts to evolve computer programs by random mutation and selection showed that evolvability is not a given, but depends on the representation of the program as a data structure, because this determines how changes in the program map to changes in its behavior. Analogously, the evolvability of organisms depends on their genotype–phenotype map. T ...
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Genetic Robustness
In evolutionary biology, robustness of a biological system (also called biological or genetic robustness) is the persistence of a certain characteristic or trait in a system under perturbations or conditions of uncertainty. Robustness in development is known as canalization. According to the kind of perturbation involved, robustness can be classified as mutational, environmental, recombinational, or behavioral robustness ''etc''. Robustness is achieved through the combination of many genetic and molecular mechanisms and can evolve by either direct or indirect selection. Several model systems have been developed to experimentally study robustness and its evolutionary consequences. Classification Mutational robustness Mutational robustness (also called mutation tolerance) describes the extent to which an organism's phenotype remains constant in spite of mutation. Robustness can be empirically measured for several genomes and individual genes by inducing mutations and measurin ...
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Pleiotropy
Pleiotropy () is a condition in which a single gene or genetic variant influences multiple phenotypic traits. A gene that has such multiple effects is referred to as a ''pleiotropic gene''. Mutations in pleiotropic genes can impact several traits simultaneously, often because the gene product is used in various cell (biology), cells and affects different biological targets through shared signaling pathways. Pleiotropy can result from several distinct but potentially overlapping mechanisms, including gene pleiotropy, developmental biology, developmental pleiotropy, and selectional pleiotropy. Gene pleiotropy occurs when a gene product interacts with multiple proteins or catalyzes different reactions. Developmental pleiotropy refers to mutations that produce several phenotype, phenotypic effects during development. Selectional pleiotropy occurs when a single phenotype influences evolutionary fitness (biology), fitness in multiple ways (depending on factors such as age and sex). T ...
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Canalization (genetics)
Canalisation is a measure of the ability of a population to produce the same phenotype regardless of variability of its environment or genotype. It is a form of evolutionary robustness. The term was coined in 1942 by C. H. Waddington to capture the fact that "developmental reactions, as they occur in organisms submitted to natural selection...are adjusted so as to bring about one definite end-result regardless of minor variations in conditions during the course of the reaction". He used this word rather than robustness to consider that biological systems are not robust in quite the same way as, for example, engineered systems. Biological robustness or canalisation comes about when developmental pathways are shaped by evolution. Waddington introduced the concept of the epigenetic landscape, in which the state of an organism rolls "downhill" during development. In this metaphor, a canalised trait is illustrated as a valley (which he called a creode) enclosed by high ridges, s ...
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Developmental Constraints
Development of the human body is the process of growth to maturity. The process begins with fertilization, where an egg released from the ovary of a female is penetrated by a sperm cell Sperm (: sperm or sperms) is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one). Animals produce motile sperm with a tail k ... from a male. The resulting zygote develops through mitosis and cell differentiation, and the resulting embryo then Implantation (human embryo), implants in the uterus, where the embryo continues development through a fetus, fetal stage until Childbirth, birth. Further growth and development continues after birth, and includes both physical development, physical and psychological development that is influenced by Genetics, genetic, hormonal, Biophysical environment, environmental and other factors. This continues throughout life: through childhood an ...
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Developmental Bias
In evolutionary biology, developmental bias refers to the production against or towards certain Ontogeny, ontogenetic trajectories which ultimately influence the direction and outcome of evolutionary change by affecting the rates, magnitudes, directions and limits of Phenotypic trait, trait evolution. Historically, the term was synonymous with developmental constraint, however, the latter has been more recently interpreted as referring solely to the negative role of development in evolution. The role of the embryo In modern evolutionary biology, the idea of developmental bias is embedded into a current of thought called ''Structuralism (biology), Structuralism'', which emphasizes the role of the organism as a ''causal'' force of evolutionary change. In the Structuralist view, phenotypic evolution is the result of the action of natural selection on previously ‘filtered’ variation during the course of ontogeny. It contrasts with the ''Functionalist'' (also “adaptationist”, ...
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Morphological Integration
Morphology, from the Greek and meaning "study of shape", may refer to: Disciplines *Morphology (archaeology), study of the shapes or forms of artifacts *Morphology (astronomy), study of the shape of astronomical objects such as nebulae, galaxies, or other extended objects *Morphology (biology), the study of the form or shape of an organism or part thereof *Morphology (folkloristics), the structure of narratives such as folk tales *Morphology (linguistics), the study of the structure and content of word forms *Morphology (sociology), the analysis of the typical social form taken by human relations and practices *Mathematical morphology, a theoretical model based on lattice theory, used for digital image processing *River morphology, the field of science dealing with changes of river platform *Urban morphology, study of the form, structure, formation and transformation of human settlements *Geomorphology, the study of landforms *Morphology (architecture and engineering), research whic ...
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Developmental Homeostasis
Development of the human body is the process of growth to maturity. The process begins with fertilization, where an egg released from the ovary of a female is penetrated by a sperm cell from a male. The resulting zygote develops through mitosis and cell differentiation, and the resulting embryo then implants in the uterus, where the embryo continues development through a fetal stage until birth. Further growth and development continues after birth, and includes both physical and psychological development that is influenced by genetic, hormonal, environmental and other factors. This continues throughout life: through childhood and adolescence into adulthood. Before birth Development before birth, or prenatal development () is the process in which a zygote, and later an embryo, and then a fetus develops during gestation. Prenatal development starts with fertilization and the formation of the zygote, the first stage in embryonic development which continues in fetal developmen ...
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Robustness (evolution)
In evolutionary biology, robustness of a biological system (also called biological or genetic robustness) is the persistence of a certain characteristic or trait in a system under perturbations or conditions of uncertainty. Robustness in development is known as canalization. According to the kind of perturbation involved, robustness can be classified as mutational, environmental, recombinational, or behavioral robustness ''etc''. Robustness is achieved through the combination of many genetic and molecular mechanisms and can evolve by either direct or indirect selection. Several model systems have been developed to experimentally study robustness and its evolutionary consequences. Classification Mutational robustness Mutational robustness (also called mutation tolerance) describes the extent to which an organism's phenotype remains constant in spite of mutation. Robustness can be empirically measured for several genomes and individual genes by inducing mutations and measur ...
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