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Tom Jefferson (epidemiologist)
Tom Jefferson is a British epidemiologist, based in Rome, Italy, who works for the Cochrane Collaboration. Jefferson is an author and editor of the Cochrane Collaboration's acute respiratory infections group, as well as part of four other Cochrane groups. He was also an advisor to the Italian National Agency for Regional Health Services. In 1999, Jefferson was one of the founding members of the Brighton Collaboration along with Harald Heijbel, Ulrich Heininger, Robert Chen, and Elisabeth Loupi. He has worked on Cochrane reviews examining the effectiveness of the anti-viral oseltamivir and the influenza vaccine. Notable work In 2009, Jefferson was hired by the governments of Britain and Australia to update a systematic review of oseltamivir. Initially he had a great deal of trouble getting results of the original trials. Previous researchers had published trials without seeing the underlying data and it appeared that some of the published papers used ghost writers. As the company, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cochrane Collaboration
Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world. The group conducts systematic reviews of health-care interventions and diagnostic tests and publishes them in the Cochrane Library. According to the Library, articles are available via one-click access, but some require paid subscription or registration before reading. A few reviews, in occupational health for example, incorporate results from non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. History Cochrane, previously known as the Cochrane Collaboration, was founded ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brighton Collaboration
The Brighton Collaboration (BC) is a non-profit global vaccine safety research network based in Basel, Switzerland. It is named after the Brighton and Hove, city in England where the idea was first formulated. History The Brighton Collaboration was launched in 2000, although the idea of the collaboration started one year earlier, following a presentation by Bob Chen at an international scientific vaccine conference in Brighton. In his talk, he stressed the need to improve vaccine safety monitoring by developing internationally accepted standards. Organization The Brighton Collaboration is a program of the The Task Force for Global Health, Task Force for Global Health, a 501(c)(3) organization, 501(c)(3) non-profit organization. It is primarily funded by the Coalition for Epidemic Preparedness Innovations (CEPI), and has received funding from a variety of scientific and public health organizations since its inception. Non-funding partners of the Collaboration include the Cou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rome, Italy
, established_title = Founded , established_date = 753 BC , founder = King Romulus ( legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = Country , subdivision_name = Italy , subdivision_type2 = Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan city , subdivision_name3 = Rome Capital , government_footnotes= , government_type = Strong Mayor–Council , leader_title2 = Legislature , leader_name2 = Capitoline Assem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oseltamivir
Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection. They recommend it to prevent infection in those at high risk, but not the general population. The Centers for Disease Control and Prevention (CDC) recommends that clinicians use their discretion to treat those at lower risk who present within 48 hours of first symptoms of infection. It is taken by mouth, either as a pill or liquid. Recommendations regarding oseltamivir are controversial as are criticisms of the recommendations. A 2014 Cochrane Review concluded that oseltamivir does not reduce hospitalizations, and that there is no evidence of reduction in complications of influenza. Two meta-analyses have concluded that benefits in those who are otherwise healthy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza Vaccine
Influenza vaccines, also known as flu shots, are vaccines that protect against infection by influenza viruses. New versions of the vaccines are developed twice a year, as the influenza virus rapidly changes. While their effectiveness varies from year to year, most provide modest to high protection against influenza. The United States Centers for Disease Control and Prevention (CDC) estimates that vaccination against influenza reduces sickness, medical visits, hospitalizations, and deaths. Immunized workers who do catch the flu return to work half a day sooner on average. Vaccine effectiveness in those over 65 years old remains uncertain due to a lack of high-quality research. Vaccinating children may protect those around them. Vaccines are an effective means to control outbreaks of many diseases. However, vaccines for respiratory viral infections such as flu are still suboptimal and do not offer broad-spectrum protection. Vaccination against influenza began in the 1930s, wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systematic Review
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on the topic, then analyzes, describes, and summarizes interpretations into a refined conclusion. For example, a systematic review of randomized controlled trials is a way of summarizing and implementing evidence-based medicine. While a systematic review may be applied in the biomedical or health care context, it may also be used where an assessment of a precisely defined subject can advance understanding in a field of research. A systematic review may examine clinical tests, public health interventions, environmental interventions, social interventions, adverse effects, qualitative evidence syntheses, methodological reviews, policy reviews, and economic evaluations. An understanding of systematic reviews and how to implement them in prac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ghost Writers
A ghostwriter is hired to write literary or journalistic works, speeches, or other texts that are officially credited to another person as the author. Celebrities, executives, participants in timely news stories, and political leaders often hire ghostwriters to draft or edit autobiographies, memoirs, magazine articles, or other written material. Memoir ghostwriters often pride themselves in "disappearing" when impersonating others since such disappearance signals the quality of their craftsmanship. In music, ghostwriters are often used to write songs, lyrics, and instrumental pieces. Screenplay authors can also use ghostwriters to either edit or rewrite their scripts to improve them. Usually, there is a confidentiality clause in the contract between the ghostwriter and the credited author that obligates the former to remain anonymous. Sometimes the ghostwriter is acknowledged by the author or publisher for their writing services, euphemistically called a "researcher" or "resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth largest pharmaceutical company in the world by revenue, and the leading provider of cancer treatments globally. The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Medicines Agency
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of medicinal products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).Set up by EC Regulation No. 2309/93 as the European Agency for the Evaluation of Medicinal Products, and renamed by EC Regulation No. 726/2004 to the European Medicines Agency, it had the acronym EMEA until December 2009. The European Medicines Agency does not call itself EMA either – it has no official acronym but may reconsider if EMA becomes commonly accepted (secommunication on new visual identity an). The EMA was set up in 1995, with funding from the European Union and the pharmaceutical industry, as well as indirect subsidy from member states, its stated intention to harmonise (but not replace) the work of existing national medicine regulatory bodies. The hope was that this plan would not o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substack
Substack is an American Online platforms for collaborative consumption, online platform that provides publishing, payment, analytics, and design infrastructure to support subscription newsletters. It allows writers to send digital newsletters directly to subscribers. Founded in 2017, Substack is headquartered in San Francisco. History Substack was founded in 2017 by Chris Best, the co-founder of Kik Messenger; Jairaj Sethi, a developer; and Hamish McKenzie, a former PandoDaily tech reporter. Best and McKenzie describe Ben Thompson's ''Stratechery,'' a subscription-based tech and media newsletter, as a major inspiration for their platform. Christopher Best operates as chief executive as of March 2019. Content Substack users range from journalists to experts to large media sites. Among the high-profile writers to have used the platform are Pulitzer-Prize-winning journalist and author Glenn Greenwald, culture critic Anne Helen Petersen, music essayist Robert Christgau, and food ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fomite
A fomite () or fomes () is any inanimate object that, when contaminated with or exposed to infectious agents (such as pathogenic bacteria, viruses or fungi), can transfer disease to a new host. Transfer of pathogens by fomites A fomite is any inanimate object (also called passive vector) that, when contaminated with or exposed to infectious agents (such as pathogenic bacteria, viruses or fungi), can transfer disease to a new host. Contamination can occur when one of these objects comes into contact with bodily secretions, like nasal fluid, vomit, or feces. Many common objects can sustain a pathogen until a person comes in contact with the pathogen, increasing the chance of infection. The likely objects are different in a hospital environment than at home or in a workplace. Fomites such as splinters, barbed wire or farmyard surfaces, including soil, feeding troughs or barn beams, have been implicated as sources of virus. Hospital fomites For humans, common hospital fomites ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harlan Krumholz
Harlan M. Krumholz, MD, SM (March 21, 1958–) is an American cardiologist, leading research scientist, and the Harold H. Hines, Jr. Professor of Medicine at Yale School of Medicine, where he has been on faculty since 1992. A pioneer in the development of the field ooutcomes research his groundbreaking contributions to science have directly led to improvements in healthcare outcomes for patients and populations. He is an international expert in the science to evaluate and improve the quality and efficiency of care, reduce disparities, improve integrity in medical research, promote better health policies and regulations, and promote patient-centeredness in research and clinical care. He is the founder and director of the Yale New Haven Hospital Center for Outcomes Research and EvaluationCORE. Early life and education Krumholz was born in St. Louis, Missouri. He attended Meadowdale High School in Dayton, Ohio. He graduated magna cum laude with a Bachelor of Science degree in Biology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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