Tim Vogels
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Tim Vogels
Tim P. Vogels is a professor of theoretical neuroscience and research leader at the Institute of Science and Technology Austria. He is primarily known for his scholarly contributions to the study of neuronal plasticity related to learning and memory in the brain. Education and early research After graduating from Gymnasium Carolinum—one of the oldest high schools in Germany—in 1997, Tim Vogels studied physics at Technische Universität Berlin in the early 2000s. He endeavoured to obtain a PhD in neuroscience with the financial support of a Fulbright Program Scholarship.  Vogels completed his doctorate research in 2007 at Brandeis University under Larry Abbott and Eve Marder's supervision and proceeded to do post-doctoral work with Rafael Yuste at Columbia University. His research involved computational modeling of synaptic plasticity rules and probing the balanced dynamics of excitatory and inhibitory properties of neocortical interneurons.  After completing his first p ...
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Institute Of Science And Technology Austria
The Institute of Science and Technology Austria (ISTA) is an international research institute in natural and formal sciences, located in Maria Gugging, Klosterneuburg, 20 km northwest of the Austrian capital of Vienna. It was established and inaugurated by the provincial government of Lower Austria and the federal government of Austria in 2009. ISTA was established on the model of the Israeli Weizmann Institute of Science by its former president Israeli physicist Haim Harari. Like in the Weizmann Institute, scientists are encouraged to pursue their own goals and ideas not restricted by government or economic interest and all research themes are interdisciplinary. As of 2023, ISTA consists of 76 research groups covering the fields of chemistry, physics, astronomy, earth science, mathematics, computer science, data science, biology, and neuroscience. It is expected to grow to about 90 research groups by 2026, and 150 groups by 2036 following commitments from the federal state ...
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Marie Skłodowska-Curie Actions
Marie Skłodowska-Curie Actions (MSCA) is a set of major research fellowships created by the European Union/European Commission to support research in the European Research Area (ERA). The Marie Skłodowska-Curie Actions are among Europe's most competitive and prestigious research and innovation fellowships. Established in 1996 as Marie Curie Actions and known since 2014 as Marie Skłodowska-Curie Actions, they aim to foster the career development and further training of researchers at all career stages. The Marie Skłodowska-Curie Actions promote interdisciplinary research and international collaborations, supporting scientists from not only within Europe but also across the globe. Marie Skłodowska-Curie Actions are currently financed through the ninth Framework Programme for Research and Technological Development (called Horizon Europe) and belong to the so-called 'first pillar' of Horizon: "Excellent Science." Through this funding scheme, the European Research Executive Agen ...
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Open Science
Open science is the movement to make scientific research (including publications, data, physical samples, and software) and its dissemination accessible to all levels of society, amateur or professional. Open science is transparent and accessible knowledge that is shared and developed through collaborative networks. It encompasses practices such as publishing open research, campaigning for open access, encouraging scientists to practice open-notebook science (such as openly sharing data and code), broader dissemination and engagement in science and generally making it easier to publish, access and communicate scientific knowledge. Usage of the term varies substantially across disciplines, with a notable prevalence in the STEM disciplines. Open research is often used quasi-synonymously to address the gap that the denotion of "science" might have regarding an inclusion of the Arts, Humanities and Social Sciences. The primary focus connecting all disciplines is the widesprea ...
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Vienna
Vienna ( ; ; ) is the capital city, capital, List of largest cities in Austria, most populous city, and one of Federal states of Austria, nine federal states of Austria. It is Austria's primate city, with just over two million inhabitants. Its larger metropolitan area has a population of nearly 2.9 million, representing nearly one-third of the country's population. Vienna is the Culture of Austria, cultural, Economy of Austria, economic, and Politics of Austria, political center of the country, the List of cities in the European Union by population within city limits, fifth-largest city by population in the European Union, and the most-populous of the List of cities and towns on the river Danube, cities on the river Danube. The city lies on the eastern edge of the Vienna Woods (''Wienerwald''), the northeasternmost foothills of the Alps, that separate Vienna from the more western parts of Austria, at the transition to the Pannonian Basin. It sits on the Danube, and is ...
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St Peter's College, Oxford
St Peter's College is a Colleges of the University of Oxford, constituent college of the University of Oxford. Located on New Inn Hall Street, Oxford, United Kingdom, it occupies the site of two of the university's academic halls of the University of Oxford, medieval halls dating back to at least the 14th century. The modern college was founded by Francis James Chavasse, former Bishop of Liverpool, opened as St Peter's Hall in 1929, and achieved full collegiate status as St Peter's College in 1961. Founded as a men's college, it has been coeducational since 1979. As of 2023, the college had an estimated financial endowment of £52.8 million. History Medieval halls Although founded in its current form in the 20th century, St Peter's occupies a central Oxford location on the site of two of the university's medieval halls. The first Master of St Peter's called the acquisition of the site "a chance of ages". The site was originally the location of Trilleck's Inn, later known ...
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Matrix (mathematics)
In mathematics, a matrix (: matrices) is a rectangle, rectangular array or table of numbers, symbol (formal), symbols, or expression (mathematics), expressions, with elements or entries arranged in rows and columns, which is used to represent a mathematical object or property of such an object. For example, \begin1 & 9 & -13 \\20 & 5 & -6 \end is a matrix with two rows and three columns. This is often referred to as a "two-by-three matrix", a " matrix", or a matrix of dimension . Matrices are commonly used in linear algebra, where they represent linear maps. In geometry, matrices are widely used for specifying and representing geometric transformations (for example rotation (mathematics), rotations) and coordinate changes. In numerical analysis, many computational problems are solved by reducing them to a matrix computation, and this often involves computing with matrices of huge dimensions. Matrices are used in most areas of mathematics and scientific fields, either directly ...
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Linear Algebra
Linear algebra is the branch of mathematics concerning linear equations such as :a_1x_1+\cdots +a_nx_n=b, linear maps such as :(x_1, \ldots, x_n) \mapsto a_1x_1+\cdots +a_nx_n, and their representations in vector spaces and through matrix (mathematics), matrices. Linear algebra is central to almost all areas of mathematics. For instance, linear algebra is fundamental in modern presentations of geometry, including for defining basic objects such as line (geometry), lines, plane (geometry), planes and rotation (mathematics), rotations. Also, functional analysis, a branch of mathematical analysis, may be viewed as the application of linear algebra to Space of functions, function spaces. Linear algebra is also used in most sciences and fields of engineering because it allows mathematical model, modeling many natural phenomena, and computing efficiently with such models. For nonlinear systems, which cannot be modeled with linear algebra, it is often used for dealing with first-order a ...
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Spiking Neural Network
Spiking neural networks (SNNs) are artificial neural networks (ANN) that mimic natural neural networks. These models leverage timing of discrete spikes as the main information carrier. In addition to Artificial neuron, neuronal and Electrical synapse, synaptic state, SNNs incorporate the concept of time into their operating model. The idea is that Artificial neuron, neurons in the SNN do not transmit information at each propagation cycle (as it happens with typical multi-layer perceptron, perceptron networks), but rather transmit information only when a membrane potential—an intrinsic quality of the neuron related to its membrane electrical charge—reaches a specific value, called the threshold. When the membrane potential reaches the threshold, the neuron fires, and generates a signal that travels to other neurons which, in turn, increase or decrease their potentials in response to this signal. A neuron model that fires at the moment of threshold crossing is also called a sp ...
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Oxford University
The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the second-oldest continuously operating university globally. It expanded rapidly from 1167, when Henry II prohibited English students from attending the University of Paris. When disputes erupted between students and the Oxford townspeople, some Oxford academics fled northeast to Cambridge, where they established the University of Cambridge in 1209. The two English ancient universities share many common features and are jointly referred to as ''Oxbridge''. The University of Oxford comprises 43 constituent colleges, consisting of 36 semi-autonomous colleges, four permanent private halls and three societies (colleges that are departments of the university, without their own royal charter). and a range of academic departments that are organised into four divisions. Each college ...
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Metaplasticity
Metaplasticity is a term originally coined by W.C. Abraham and M.F. Bear to refer to the plasticity of synaptic plasticity. Until that time synaptic plasticity had referred to the plastic nature of ''individual'' synapses. However this new form referred to the plasticity of the plasticity itself, thus the term ''meta''-plasticity. The idea is that the synapse's previous history of activity determines its current plasticity. This may play a role in some of the underlying mechanisms thought to be important in memory and learning such as long-term potentiation (LTP), long-term depression (LTD) and so forth. These mechanisms depend on current synaptic "state", as set by ongoing extrinsic influences such as the level of synaptic inhibition, the activity of modulatory afferents such as catecholamines, and the pool of hormones affecting the synapses under study. Recently, it has become clear that the prior history of synaptic activity is an additional variable that influences the synaptic ...
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Inhibitory Postsynaptic Potential
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.Purves et al. Neuroscience. 4th ed. Sunderland (MA): Sinauer Associates, Incorporated; 2008. The opposite of an inhibitory postsynaptic potential is an excitatory postsynaptic potential (EPSP), which is a synaptic potential that makes a postsynaptic neuron ''more'' likely to generate an action potential. IPSPs can take place at all chemical synapses, which use the secretion of neurotransmitters to create cell-to-cell signalling. EPSPs and IPSPs compete with each other at numerous synapses of a neuron. This determines whether an action potential occurring at the presynaptic terminal produces an action potential at the postsynaptic membrane. Some common neurotransmitters involved in IPSPs are GABA and glycine. Inhibitory presynaptic neurons release neurotransmitters that then bind to the postsynaptic receptors; this induces a ...
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