Tilapinevirus
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Tilapinevirus
Tilapia lake virus (TiLV), is a negative-strand RNA virus that infects both wild and aquacultured populations of tilapia. It is the only species in the monotypic taxon, monotypic genus ''Tilapinevirus'', which in turn is the only genus in the family ''Amnoonviridae''. Thus far it has been recorded in various regions across Asia, Africa, and South America. The virus was first discovered and identified in 2014 when the Sea of Galilee (Kinneret Lake) in Israel experienced a major noticeable decline in tilapia catch quantities. Classification Tilapia lake virus is a negative-sense, single-stranded RNA virus. Structure Electron microscopy has revealed tilapia lake virus to be an enveloped particle with a helical nucleocapsid that is 55–100 nm in diameter. Further information of the viral structure is not yet available, however, as TiLV is described to be an orthomyxo-like virus it may share similar structural features, like surface glycoproteins and a helical nucleocapsid, ...
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Negative-strand RNA Virus
Negative-strand RNA viruses (−ssRNA viruses) are a group of related viruses that have Sense (molecular biology), negative-sense, single-stranded genomes made of ribonucleic acid (RNA). They have genomes that act as complementary strands from which messenger RNA (mRNA) is synthesized by the viral enzyme RNA-dependent RNA polymerase (RdRp). During replication of the viral genome, RdRp synthesizes a positive-sense antigenome that it uses as a template to create genomic negative-sense RNA. Negative-strand RNA viruses also share a number of other characteristics: most contain a viral envelope that surrounds the capsid, which encases the viral genome, −ssRNA virus genomes are usually linear, and it is common for their genome to be segmented. Negative-strand RNA viruses constitute the phylum ''Negarnaviricota'', in the kingdom ''Orthornavirae'' and realm ''Riboviria''. They are descended from a common ancestor that was a Double-stranded RNA viruses, double-stranded RNA (dsRNA) virus ...
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Virus Replication
Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome and packaging these copies, the virus continues infecting new hosts. Replication between viruses is greatly varied and depends on the type of genes involved in them. Most DNA viruses assemble in the nucleus while most RNA viruses develop solely in cytoplasm. Viral production / replication Viruses multiply only in living cells. The host cell must provide the energy and synthetic machinery and the low-molecular-weight precursors for the synthesis of viral proteins and nucleic acids. Virus replication occurs in seven stages: # Attachment # Entry (penetration) # Uncoating # Replication # Assembly # Maturation # Release (liberation stage). Attachment It is the first step of viral replication. Some viruses attach to the cell membrane of the h ...
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Vertical Transmission
Vertical transmission of symbionts is the transfer of a microbial symbiont from the parent directly to the offspring.  Many metazoan species carry symbiotic bacteria which play a mutualistic, commensal, or parasitic role.  A symbiont is acquired by a host via horizontal, vertical, or mixed transmission. Fitness benefits Vertical transmission, passage of symbiotic microflora from parents to offspring, is common in species of animals which have parental care. There are fitness benefits in providing youths with established microorganism community early on. # Immune system development: parents microbes prime young immune system. # Disease resistance: because skin is already colonized by parental microbes, pathogen flora has a harder time to establish itself. # Digestive help: parental microbes might help with digestion, as a result, the young ones can survive on a diet which would not meet their nutritious needs otherwise. # Environmental adaptation: microflora might help t ...
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Influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) i ...
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Viral Hemorrhagic Septicemia
Viral hemorrhagic septicemia (VHS) is a deadly infectious fish disease caused by Viral hemorrhagic septicemia virus. It afflicts over 50 species of freshwater and marine fish in several parts of the Northern Hemisphere. Different strains of the virus occur in different regions, and affect different species. There are no signs that the disease affects human health. VHS is also known as Egtved disease, and the virus as Egtved virus. Historically, VHS was associated mostly with freshwater salmonids in western Europe, documented as a pathogenic disease among cultured salmonids since the 1950s. Today it is still a major concern for many fish farms in Europe and is therefore being watched closely by the European Community Reference Laboratory for Fish Diseases. It was first discovered in the US in 1988 among salmon returning from the Pacific in Washington (state), Washington state. This North American genotype was identified as a distinct, more marine-stable strain than the European ge ...
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Anemia
Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function. The name is derived . When anemia comes on slowly, the symptoms are often vague, such as Fatigue, tiredness, weakness, shortness of breath, headaches, and a Exercise intolerance, reduced ability to exercise. When anemia is acute, symptoms may include confusion, lightheadedness, feeling like one is going to pass out, Syncope (medicine), loss of consciousness, and polydipsia, increased thirst. Anemia must be significant before a person becomes noticeably Pallor, pale. Additional symptoms may occur depending on the underlying cause. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cel ...
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Pallor
Pallor is a pale color of the skin that can be caused by illness, emotional shock or stress, stimulant use, or anemia, and is the result of a reduced amount of oxyhaemoglobin and may also be visible as pallor of the conjunctivae of the eyes on physical examination. Pallor is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause. It is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar presentations such as hypopigmentation (lack or loss of skin pigment) or simply a lightly-melanated complexion. Causes * migraine attack or headache * excess estradiol and/or estrone * osteoporosis * emotional response, due to fear, embarrassment, grief, rage * anorexia * anemia, due to blood loss, poor nutrition, or underlying disease such as sickle cell anemia * iron deficiency * vitamin B12 deficien ...
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Exophthalmos
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. Exophthalmos has endocrine causes. In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and extraocular muscles, which can be visualized by CT or MRI. If left untreated, exophthalmos can cause the eyelids to fail to close during sleep, leading to corneal dryness and damage. Another possible complication is a form of redness or irritation called superior limbic keratoconjunctivitis, in which the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the disp ...
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Aeromonas
''Aeromonas'' is a genus of Gram-negative, Facultative anaerobic organism, facultative anaerobic, rod-shaped, bacteria that morphologically resemble members of the family Enterobacteriaceae. Most of the 14 described species have been associated with human diseases. The most important pathogens are ''Aeromonas hydrophila, A. hydrophila'', ''Aeromonas caviae, A. caviae'', and ''Aeromonas veronii, A. veronii'' biovar ''sobria''. The organisms are ubiquitous in fresh and brackish water. They group with the gamma subclass of the Proteobacteria. Two major diseases associated with ''Aeromonas'' are gastroenteritis and wound infections, with or without bacteremia. Gastroenteritis typically occurs after the ingestion of contaminated water or food, whereas wound infections result from exposure to contaminated water. In its most severe form, ''Aeromonas'' spp. can cause necrotizing fasciitis, which is life-threatening, usually requiring treatment with antibiotics and even amputation. Altho ...
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Fin Rot
Fin rot is the phenomenon where the fins of a fish gradually decay and are eventually destroyed. Typically, fin rot is either a symptom of a disease, oftentimes a bacterial or fungal infection, but it can also sometimes be a disease by itself. Fin rot is most often observed in aquaria and aquaculture, but can also occur in natural populations. Fin rot can be the result of a bacterial infection ('' Pseudomonas fluorescens'', which causes a ragged rotting of the fin), or as a fungal A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as one of the tradit ... infection (which rots the fin more evenly and is more likely to produce a white "edge"). Sometimes, both types of infection are seen together. Infection is commonly brought on by bad water conditions, injury, poor diet, stress, or as a secondary infecti ...
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Lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by injury or diseases. The term ''Lesion'' is derived from the Latin meaning "injury". Lesions may occur in both plants and animals. Types There is no designated classification or naming convention for lesions. Because lesions can occur anywhere in the body and their definition is so broad, the varieties of lesions are virtually endless. Generally, lesions may be classified by their patterns, sizes, locations, or causes. They can also be named after the person who discovered them. For example, Ghon lesions, which are found in the lungs of those with tuberculosis, are named after the lesion's discoverer, Anton Ghon. The characteristic skin lesions of a varicella zoster virus infection are called '' chickenpox''. Lesions of the teeth are usually called dental caries, or "cavities". Location Lesions are often classified by their tissue types or locations. For example, "skin lesions" or ...
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Lethargy
Lethargy is a state of tiredness, sleepiness, weariness, fatigue, sluggishness, or lack of energy. It can be accompanied by depression, decreased motivation, or apathy. Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom, or a symptom of an underlying illness or disorder. It may also be a side effect of medication or caused by an interaction between medications or medication(s) and alcohol. It may also be an altered level of consciousness. When part of a normal response, lethargy often resolves with rest, adequate sleep, decreased stress, physical exercise, and good nutrition. Its symptoms, however, can last days or even months, so it can be a sign of a recent underlying illness or infection if it does not resolve normally. See also * Clinical depression * Disorders of diminished motivation * Encephalitis lethargica * Sleep apnea * Sleep deprivation * Somnolence Somnolence ( ...
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