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Thomas Tuschl
Thomas Tuschl (born 1 June 1966) is a German biochemist and molecular biologist, known for his research on RNA. Biography Tuschl was born in Altdorf bei Nürnberg. After graduating in Chemistry from Regensburg University, Tuschl received his PhD in 1995 from the Max Planck Institute for Experimental Medicine in Göttingen. He spent four years as a post-doctoral fellow at the Whitehead Institute of the Massachusetts Institute of Technology (MIT) in Cambridge, USA. In 1999 he returned to Göttingen, to continue his research at the Max Planck Institute for Biophysical Chemistry. There he received international recognition in Genetics for his studies of RNA interference in collaboration with the laboratory of Klaus Weber. This enables "switching off" certain genes by introducing synthetic short RNA into the cell. The mRNA is destroyed and the gene is deactivated. Possible future applications of this method include treatment of tumors or genetic disorders. The function of certain gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Altdorf Bei Nürnberg
Altdorf bei Nürnberg ( , ; ) is a town in south-eastern Germany. It is situated east of Nuremberg, in the district Nürnberger Land. Its name literally means “Altdorf near Nuremberg”, to distinguish it from other Altdorfs. History Altdorf is first mentioned in 1129. In 1504 the town was conquered by the Free Imperial City of Nuremberg. In the 16th century, the city government of Nuremberg founded an academy in Altdorf, which became a university in 1622. The university lasted until 1809. Among the alumni of the University of Altdorf were the soldier Albrecht von Wallenstein and the philosopher and scientist Gottfried Leibniz. Discovery of teleosaur fossils Teleosaur remains have been known from Altdorf bei Nürnberg since 1832,Meyer, H. von, (1832), ''Paleologica zur Geschichte der Erde'', Frankfurt am Main, 560 p but none have been placed in a specific genus yet. Economy Even though the times of its once famous university have long passed, Altdorf is the seat of severa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (biology)
The cell is the basic structural and functional unit of all life, forms of life. Every cell consists of cytoplasm enclosed within a Cell membrane, membrane; many cells contain organelles, each with a specific function. The term comes from the Latin word meaning 'small room'. Most cells are only visible under a light microscope, microscope. Cells Abiogenesis, emerged on Earth about 4 billion years ago. All cells are capable of Self-replication, replication, protein synthesis, and cell motility, motility. Cells are broadly categorized into two types: eukaryotic cells, which possess a Cell nucleus, nucleus, and prokaryotic, prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular organism, multicellular, such as some algae, plants, animals, and fungi. Eukaryotic cells contain organelles including Mitochondrion, mitochondria, which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1966 Births
Events January * January 1 – In a coup, Colonel Jean-Bédel Bokassa takes over as military ruler of the Central African Republic, ousting President David Dacko. * January 3 – 1966 Upper Voltan coup d'état: President Maurice Yaméogo is deposed by a military coup in the Republic of Upper Volta (modern-day Burkina Faso). * January 10 ** Pakistani–Indian peace negotiations end successfully with the signing of the Tashkent Declaration, a day before the sudden death of Indian prime minister Lal Bahadur Shastri. ** Georgia House of Representatives, The House of Representatives of the US state of Georgia refuses to allow African-American representative Julian Bond to take his seat, because of his anti-war stance. * January 15 – 1966 Nigerian coup d'état: A bloody military coup is staged in Nigeria, deposing the civilian government and resulting in the death of Prime Minister Abubakar Tafawa Balewa. * January 17 ** The Nigerian coup is overturned by another faction of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Klung Wilhelmy Science Award
The Klung Wilhelmy Science Award is an annual German award in the field of science, alternating annually between the categories of chemistry and physics. It is bestowed upon outstanding younger German scientists under the age of 40. Previous award names *1973 to 2001 – Otto-Klung Award *2001 to 2007 – Otto-Klung-Weberbank Award *2007 to 2013 – Klung-Wilhelmy-Weberbank Award Selection process The prizewinners are selected by permanent committees at the Institutes of Chemistry and Biochemistry and the Department of Physics at the Freie Universität Berlin, Free University of Berlin, with additional input from professors at other universities. Proposals and nominations by nationally and internationally renowned scientists are also taken into consideration. Self-nominations will not be accepted. The final decision on the selection recommendations is made by the following foundations: the Otto-Klung-Stiftung, Otto Klung Foundation at the Freie Universität Berlin, Free Univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Baulcombe
Sir David Charles Baulcombe (born 7 April 1952) is a British plant scientist and geneticist. he was Head of Group, Gene Expression, in the Department of Plant Sciences at the University of Cambridge, and the Edward Penley Abraham Royal Society Research Professor and Regius Professor of Botany Emeritus at Cambridge. He held the Regius botany chair in that department from 2007 to 2020. Early life and education David Baulcombe was born on 7 April 1952 in the United Kingdom, in Solihull, Warwickshire, (in England's Midlands), into "a non-scientific family". He received his Bachelor of Science degree in botany from the University of Leeds in 1973, at the age of 21, and continued his studies at the University of Edinburgh, receiving his Doctor of Philosophy degree in 1976/1977 Note, the EThOS link appearing here is a . (for research on Messenger RNA in vascular plants supervised by John Ingle). Career After his PhD, Baulcombe spent the next three years as a postdoctoral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meyenburg Prize
The Meyenburg Prize is awarded for outstanding achievements in cancer research by the Meyenburg Foundation in support of the German Cancer Research Center, Heidelberg (DKFZ), which is the largest biomedical research institution in Germany. The prize has been awarded annually since 1981, and currently has an honorarium of €50,000. List of Recipients SourceMeyenburg Award Winners * 1981 Werner Franke, Werner W. Franke * 1982/1983 Holger Kirchner and * 1984 Lutz Gissmann * 1985 Volker Sturm * 1986 Karin Mölling * 1987 Mary Osborn * 1988 Elisabeth Gateff * 1989 * 1990 * 1991 Hans-Georg Rammensee * 1992 Walter Birchmeier * 1993 Johannes Gerdes * 1994 * 1995 David Lane (oncologist), David P. Lane * 1996 Peter H. Krammer * 1997 Patrick S. Moore and Yuan Chang * 1998 Richard D. Wood * 1999 Carl-Henrik Heldin * 2000 Matthias Mann * 2001 * 2002 Andrew Fire * 2004 Erich Nigg, Erich A. Nigg * 2005 Thomas Tuschl * 2006 Elizabeth Blackburn * 2007 Shinya Yamanaka * 2008 Hans Clevers * 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernst Schering Prize
The Ernst Schering Prize is awarded annually by the Ernst Schering Foundation for especially outstanding basic research in the fields of medicine, biology or chemistry anywhere in the world. Established in 1991 by the Ernst Schering Research Foundation, and named after the German apothecary and industrialist, Ernst Christian Friedrich Schering, who founded the Schering Corporation, the prize is now worth €50,000. Recipients SourceSchering Foundation *1992 , (Center for Molecular Biology, University of Heidelberg, Germany) *1993 Christiane Nüsslein-Volhard, ( Max Planck Institute for Developmental Biology in Tübingen, Germany) *1994 Bert Vogelstein, (Oncology Center, Johns Hopkins University, Baltimore, Maryland, US) *1995 Yasutomi Nishizuka, ( Kobe University, Japan) *1996 Judah Folkman, ( Harvard Medical School, Harvard University, Boston, US) *1997 Johann Mulzer, (Institute for Organic Chemistry, University of Vienna, Austria) *1998 Ilme Schlichting, ( Max Planck In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Delbrück Medal
The Max Delbrück Medal has been awarded annually from 1992 to 2013 by the Max Delbrück Center for Molecular Medicine (German: ''Max-Delbrück-Centrum für Molekulare Medizin'' or MDC). Named after the German biophysicist Max Delbrück, it is presented in Berlin to an outstanding scientist on the occasion of the annual "Berlin Lecture on Molecular Medicine", which the MDC organizes together with other Berlin research institutions and Bayer HealthCare. The award recipient usually delivers a lecture after the award. Recipients SourceMDC* 1992: Günter Blobel, Rockefeller University of New York, US * 1993: ''no award'' * 1994: Sydney Brenner, Cambridge University, England * 1995: Jean-Pierre Changeux, Pasteur Institute, Paris * 1996: Robert Allan Weinberg, Whitehead Institute, Cambridge, US * 1997: Charles Weissmann, Zürich University, Switzerland * 1998: Svante Pääbo, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany * 1999: Paul Berg, Stanford University, U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernst Jung Prize
The Ernst Jung Prize is a prize awarded annually for excellence in biomedical sciences. The Ernst Jung Foundation, funded by Hamburg merchant Ernst Jung in 1967, has awarded the Ernst Jung Prize in Medicine, now €300,000, since 1976, and the lifetime achievement Ernst Jung Gold Medal for Medicine since 1990. Ernst Jung Prize for Medicine SourceJung Foundation *1976: Donald Henderson and Lorenz Zimmerman *1977: and John B. West *1979: Karl Lennert and *1980: , Alan Parks and *1981: David E. Kuhl *1982: Hartmut Wekerle and Rolf M. Zinkernagel *1983: and Richard Lower *1984: , Werner Franke and Klaus Weber *1985: Hendrik Coenraad Hemker, Rudolf Pichlmayr and Peter K. Vogt *1986: Albrecht Fleckenstein *1987: Peter Richardson and *1988: Helmut Sies and Charles Weissmann *1989: and Jon van Rood *1990: Gerhard Giebisch and *1991: David Ho and *1992: Roy Yorke Calne and *1993: Charles A. Dinarello and Robert Machemer *1994: and Wolf Singer *1995: Antho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Craig Mello
Craig Cameron Mello (born October 18, 1960) is an American biologist and professor of molecular medicine at the University of Massachusetts Medical School in Worcester, Massachusetts. He was awarded the 2006 Nobel Prize for Physiology or Medicine, along with Andrew Z. Fire, for the discovery of RNA interference. This research was conducted at the Carnegie Institution of Washington and published in 1998. Mello has been a Howard Hughes Medical Institute investigator since 2000. Early life Mello was born in New Haven, Connecticut on October 18, 1960. He was the third child of James and Sally Mello. His father, James Mello, was a paleontologist and his mother, Sally Mello, was an artist. His paternal grandparents immigrated to the US from the Portuguese islands of Azores. His parents met while attending Brown University and were the first children in their respective families to attend college. His grandparents on both sides withdrew from school as teenagers to work for their fam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Andrew Fire
Andrew Zachary Fire (born April 27, 1959) is an American biologist and professor of pathology and of genetics at the Stanford University School of Medicine. He was awarded the 2006 Nobel Prize in Physiology or Medicine, along with Craig C. Mello, for the discovery of RNA interference (RNAi). This research was conducted at the Carnegie Institution of Washington and published in 1998. Biography Andrew Z Fire was born in Palo Alto, California and raised in Sunnyvale, California in a Jewish family. He graduated from Fremont High School. He attended the University of California, Berkeley for his undergraduate degree, where he received a B.A. in mathematics in 1978 at the age of 19. He then proceeded to the Massachusetts Institute of Technology, where he received a Ph.D. in biology in 1983 under the mentorship of Nobel laureate geneticist Phillip Sharp. Fire moved to Cambridge, England, as a Helen Hay Whitney Postdoctoral Fellow. He became a member of the MRC Laboratory of M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MicroRNA
Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in messenger RNA (mRNA) molecules, then silence said mRNA molecules by one or more of the following processes: * Cleaving the mRNA strand into two pieces. * Destabilizing the mRNA by shortening its poly(A) tail. * Reducing translation of the mRNA into proteins. In cells of humans and other animals, miRNAs primarily act by destabilizing the mRNA. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short stem-loops (hairpins), whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode ov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
