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Synephrine
Synephrine, or, more specifically, ''p''-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its ''m''-substituted analog known as neo-synephrine. ''p''-Synephrine (or formerly Sympatol and oxedrine [British Approved Name, BAN]) and ''m''-synephrine are known for their longer acting adrenergic effects compared to epinephrine and norepinephrine. This substance is present at very low concentrations in common foodstuffs such as orange juice and other orange (''Citrus'' species) products, both of the "sweet" and "bitter" variety. The preparations used in traditional Chinese medicine (TCM), also known as Zhi Shi (枳实), are the immature and dried whole oranges from ''Citrus aurantium'' (''Fructus Aurantii Immaturus''). Extracts of the same material or purified synephrine are also marketed in the US, sometimes in combination with caffeine, as a weight-loss-promoting dietary supplement for oral consumption. While the traditi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylephrine
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository. It can also be applied to the skin. Common side effects when taken by mouth or injected include nausea, vomiting, headache, and anxiety. Use on hemorrhoids is generally well tolerated. Severe side effects may include a slow heart rate, intestinal ischemia, chest pain, kidney failure, and tissue death at the site of injection. It is unclear whether its use during pregnancy and breastfeeding is safe. Phenylephrine is a selective α1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. It causes constriction of both arteries and veins. Phenylephrine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citrus Aurantium
The bitter orange, sour orange, Seville orange, bigarade orange, or marmalade orange is the hybrid citrus tree species ''Citrus'' × ''aurantium'', and its fruit. It is native to Southeast Asia and has been spread by humans to many parts of the world. It is a cross between the pomelo, ''Citrus maxima'', and the wild type mandarin orange, ''Citrus reticulata''. The bitter orange is used to make essential oil, used in foods, drinks, and pharmaceuticals. The Seville orange is prized for making British orange marmalade. Definition In some proposed systems, the species ''Citrus'' × ''aurantium'' includes not only the bitter orange proper, but all other Hybrid (biology), hybrids between the pomelo and the wild type mandarin orange, mandarin, namely the sweet orange, the grapefruit, and all cultivated mandarin orange, mandarins. p. 69–70 This article only deals with the bitter orange proper. History The bitter orange, like many cultivated ''Citrus'' species, is a hybrid, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hay-fever
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. It is classified as a type I hypersensitivity reaction. Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of pollen exposure. Many people with allergic rhinitis also have asthma, allergic conjunctivitis, or atopic dermatitis. Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics and environmental exposures contribute to the development of allergies. Growing up on a farm and having multiple older siblings are as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patchouli
Patchouli (also spelled patchouly or pachouli; ; '' Pogostemon cablin'') is a species of flowering plant in the family Lamiaceae, commonly called the mint or deadnettle family. The plant grows as a bushy perennial herb, with erect stems reaching up to in height and bearing small, pale, pink-white flowers. It is native to the island region of Southeast Asia, including Sri Lanka, Indonesia, the Malay Peninsula, New Guinea, and the Philippines. It is also found in many parts of Nepal and North East India. Noted for its fragrant essential oil, it has many commercial uses and is now extensively cultivated in tropical climates around the world, especially in Asia, Madagascar, South America, and the Caribbean. , global demand for patchouli oil is over per year, of which over 90% is produced by Indonesia. Etymology The word derives from the Tamil ''patchai'' () or paccuḷi, meaning "green", and ''ellai'' (), meaning "leaf". Cultivation Patchouli grows well in warm to tropical clim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pogostemon Cablin
Patchouli (also spelled patchouly or pachouli; ; ''Pogostemon cablin'') is a species of flowering plant in the family Lamiaceae, commonly called the mint or deadnettle family. The plant grows as a bushy perennial herb, with erect stems reaching up to in height and bearing small, pale, pink-white flowers. It is native to the island region of Southeast Asia, including Sri Lanka, Indonesia, the Malay Peninsula, New Guinea, and the Philippines. It is also found in many parts of Nepal and North East India. Noted for its fragrant essential oil, it has many commercial uses and is now extensively cultivated in tropical climates around the world, especially in Asia, Madagascar, South America, and the Caribbean. , global demand for patchouli oil is over per year, of which over 90% is produced by Indonesia. Etymology The word derives from the Tamil ''patchai'' () or paccuḷi, meaning "green", and ''ellai'' (), meaning "leaf". Cultivation Patchouli grows well in warm to tropical clima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zanthoxylum
''Zanthoxylum'' is a genus of about 250 species of deciduous and evergreen trees, shrubs and climbers in the Family (biology), family Rutaceae that are native to warm temperate and Subtropics, subtropical areas worldwide. It is the type genus of the tribe Zanthoxyleae in the subfamily Rutoideae#Zanthoxyleae, Rutoideae. Several of the species have yellow Wood#Heartwood and sapwood, heartwood, to which their generic name alludes. Several species are cultivated for their use as spices, notably including Sichuan pepper. Description Plants in the genus ''Zanthoxylum'' are typically dioecious shrubs, trees or woody climbers armed with Trichome#Plant trichomes, trichomes. The leaves are arranged alternately and are usually Pinnation, pinnate or Glossary of leaf morphology#trifoliate, trifoliate. The flowers are usually arranged in panicles and usually function as male or female flowers with four sepals and four petals, the sepals remaining attached to the fruit. Male flowers have f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evodia
''Euodia'' is a plant genus in the family Rutaceae. ''Euodia'' is sometimes misspelled as ''Evodia''. The species now included in the genus ''Tetradium'' were previously included in ''Euodia'', and may be commonly referred to as euodia. Fossil record Fossil seeds of ''Euodia costata'' have been recovered from Eocene sediments at Hordle, Hants, southern England. A fossil species, ''Euodia lignita'', has been described from Oligocene Brandon Lignite sediments in Vermont, United States. Species * '' Euodia elleryana'' * '' Euodia hortensis'' J.R.Forst. & G.Forst. * '' Euodia hylandii'' * '' Euodia lunuankenda'' * '' Euodia macrocarpa'' * ''Euodia pubifolia'' * ''Euodia schullei Euodia may refer to: * Euodia (diatom), ''Euodia'' (diatom), a genus in the family Eunotiaceae * Euodia (plant), ''Euodia'' (plant), a plant genus in the family Rutaceae ** ''Tetradium'', related genus known in cultivation in English-speaking countr ...'' Warb. * '' Euodia simplicifolia'' * '' Euodia tieta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Product
A natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development of the field of organic chemistry by providing challenging synthetic targets). The term ''natural product'' has also been extended for commercial purposes to refer to cosmetics, dietary supplements, and foods produced from natural sources without added artificial ingredients. Within the field of organic chemistry, the definition of natural products is usually restricted to organic compounds isolated from natural sources that are produced by the pathways of primary or secondary metabolism. Within the field of medicinal chemistry, the definition is often further restricted to secondary metabolites. Secondary metabolites (or specialized meta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotransmitters
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. Some neurotransmitters are also stored in large dense core vesicles. The neurotransmitter's effect on the target cell is determined by the receptor it binds to. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available and often require a small number of biosynthetic steps for conversion. Neurotransmitters are essential to the function of complex neural systems. The exact number of unique neurotransmitters in humans is unknown, but more than 100 have been identified. Common neurotransmitters include glutamate, GABA, acetylcholine, glyci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation. Phenethylamine is sold as a dietary supplement for purported mood and weight loss-related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by mon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
