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Split-brain
Split-brain or callosal syndrome is a type of disconnection syndrome when the corpus callosum connecting the two hemispheres of the brain is severed to some degree. It is an association of symptoms produced by disruption of, or interference with, the connection between the hemispheres of the brain. The surgical operation to produce this condition ( corpus callosotomy) involves transection of the corpus callosum, and is usually a last resort to treat refractory epilepsy. Initially, partial callosotomies are performed; if this operation does not succeed, a complete callosotomy is performed to mitigate the risk of accidental physical injury by reducing the severity and violence of epileptic seizures. Before using callosotomies, epilepsy is instead treated through pharmaceutical means. After surgery, neuropsychological assessments are often performed. After the right and left brain are separated, each hemisphere will have its own separate perception, concepts, and impulses to act ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Michael Gazzaniga
Michael S. Gazzaniga (born December 12, 1939) is an American Cognitive neuroscience, cognitive neuroscientist who is an emeritus professor of psychology at the University of California, Santa Barbara. He is the founder and retired director of the SAGE Center for the Study of the Mind at UCSB (2006–2023). Biography In 1961, Gazzaniga graduated from Dartmouth College with a B.A in Zoology. In 1964, he received a Ph.D. in psychobiology from the California Institute of Technology, where he carried out research on human split-brain patients for his doctoral thesis under Roger Sperry. In his subsequent work he has made important advances in our understanding of Lateralization of brain function, which functions are lateralized in the brain and how the left and right cerebral hemispheres communicate with one another. Career He has had a distinguished career in the field of cognitive neuroscience. Gazzaniga's academic career began as an assistant professor of psychology at University ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Roger Sperry
Roger Wolcott Sperry (August 20, 1913 – April 17, 1994) was an American neuropsychologist, neurobiologist, cognitive neuroscientist, and Nobel laureate who, together with David H. Hubel and Torsten Nils Wiesel, won the 1981 Nobel Prize in Medicine for his work with split-brain research. A ''Review of General Psychology'' survey, published in 2002, ranked Sperry as the 44th most cited psychologist of the 20th century. Early life and education Sperry was born in Hartford, Connecticut, to Francis Bushnell and Florence Kraemer Sperry. His father was in banking, and his mother trained in business school. He was raised in an upper middle-class environment, which stressed academic achievement. Roger had one brother, Russell Loomis. Their father died when Roger was 11. Afterwards, his mother became assistant to the principal in the local high school. Sperry went to Hall High School in West Hartford, Connecticut, where he was a star athlete in several sports, and did well enough ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Corpus Callosotomy
A corpus callosotomy () is a palliative surgical procedure for the treatment of medically refractory epilepsy. The procedure was first performed in 1940 by William P. van Wagenen. In this procedure, the corpus callosum is cut through, in an effort to limit the spread of epileptic activity between the two halves of the brain. Although the corpus callosum is the largest white matter tract connecting the hemispheres, some limited interhemispheric communication is still possible via the anterior and posterior commissures. After the operation, however, the brain often struggles to send messages between hemispheres, which can lead to side effects such as speech irregularities, disconnection syndrome, and alien hand syndrome. History The first instances of corpus callosotomy were performed in the 1940s by William P. van Wagenen, who co-founded and served as president of the American Association of Neurological Surgeons. Attempting to treat epilepsy, van Wagenen studied and publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Disconnection Syndrome
Disconnection syndrome is a general term for a collection of neurological symptoms caused – via lesions to association fiber, associational or commissural fiber, commissural nerve fibres – by damage to the white matter axons of communication pathways in the cerebrum (not to be confused with the cerebellum), independent of any lesions to the cerebral cortex, cortex. The behavioral effects of such disconnections are relatively predictable in adults. Disconnection syndromes usually reflect circumstances where regions A and B still have their functional specializations except in domains that depend on the interconnections between the two regions. split-brain, Callosal syndrome, or split-brain, is an example of a disconnection syndrome from damage to the corpus callosum between the two hemispheres of the brain. Disconnection syndrome can also lead to aphasia, left-sided apraxia, and tactile aphasia, among other symptoms. Other types of disconnection syndrome include conduction aphas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Jerre Levy
Jerre Levy (born April 7, 1938) is an American psychologist and researcher of the brain. She has studied the relationship between the cerebral hemispheres and visual-oriented versus language-oriented tasks in split-brain surgery patients. Jerre Levy was born in Birmingham, Alabama on April 7, 1938. She earned a degree in psychology from the University of Miami in 1962. She attended graduate school there for a year and a half before transferring to Caltech, where she worked in Roger Sperry's laboratory. She received her PhD in 1970. From 1972 to 1977 Levy taught at the University of Pennsylvania. She then became a professor at the University of Chicago. She has also found evidence that the left hemisphere specializes in linear reasoning, while the right brain is more involved in holistic reasoning. She claims that the two hemispheres of the brain The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate ani ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Pure Alexia
Pure alexia, also known as agnosic alexia or alexia without agraphia or pure word blindness, is one form of alexia which makes up "the peripheral dyslexia" group. Individuals who have pure alexia have severe reading problems while other language-related skills such as naming, oral repetition, auditory comprehension or writing are typically intact. Pure alexia is also known as: "alexia without agraphia", "letter-by-letter dyslexia", "spelling dyslexia", or "word-form dyslexia". Another name for it is "Dejerine syndrome", after Joseph Jules Dejerine, who described it in 1892; however, when using this name, it should not be confused with medial medullary syndrome which shares the same eponym. Classification Pure alexia results from cerebral lesions in circumscribed brain regions and therefore belongs to the group of acquired reading disorders, alexia, as opposed to developmental dyslexia found in children who have difficulties in learning to read. Causes Pure alexia almost alwa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Caltech
The California Institute of Technology (branded as Caltech) is a private university, private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of Institute of Technology (United States), institutes of technology in the United States that are devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery Hale, Arthur Amos Noyes, and Robert Andrews Millikan in the early 20th century. The vocational and preparatory schools were disbanded and spun off in 1910, and the college assumed its present name in 1920. In 1934, Caltech was elected to the Association of American Universities, and the antecedents of NASA's Jet Propulsion Laboratory, which Caltech continues to manage and operate, were established between 1936 and 1943 under ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Medicine or Physiology, Chemistry, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2024, 115 Nobel Prizes in Physiology or Medicine have been awarded to 229 laureates, 216 men and 13 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucida ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Posterior (anatomy)
Standard anatomical terms of location are used to describe unambiguously the anatomy of humans and other animals. The terms, typically derived from Latin or Greek language, Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes, axes. The meaning of terms that are used can change depending on whether a vertebrate is a biped or a quadruped, due to the difference in the neuraxis, or if an invertebrate is a non-bilaterian. A non-bilaterian has no anterior or posterior surface for example but can still have a descriptor used such as proximal or distal in relation to a body part that is nearest to, or furthest from its middle. International organisations have determined vocabularies that are often used as standards for subdisciplines of anatomy. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Pineal Gland
The pineal gland (also known as the pineal body or epiphysis cerebri) is a small endocrine gland in the brain of most vertebrates. It produces melatonin, a serotonin-derived hormone, which modulates sleep, sleep patterns following the diurnal cycles. The shape of the gland resembles a pine cone, which gives it its name. The pineal gland is located in the epithalamus, near the center of the brain, between the two cerebral hemisphere, hemispheres, tucked in a groove where the two halves of the thalamus join. It is one of the neuroendocrinology, neuroendocrine Circumventricular organs, secretory circumventricular organs in which capillaries are mostly Vascular permeability, permeable to solutes in the blood. The pineal gland is present in almost all vertebrates, but is absent in Protochordata, protochordates in which there is a simple pineal homologue. The hagfish, archaic vertebrates, lack a pineal gland. In some species of amphibians and reptiles, the gland is linked to a light-s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Pinealoma
A pinealoma is a tumor of the pineal gland, a part of the brain that produces melatonin. If a pinealoma destroys the cells of the pineal gland in a child, it can cause precocious puberty. Signs and symptoms The pineal gland produces the hormone melatonin which plays a role in regulating circadian rhythms. A pinealoma may disrupt production of this hormone, and insomnia may result. Frequently, paralysis of upward gaze along with several ocular findings such as convergence retraction nystagmus and eyelid retraction also known as Collier's sign and Light Near Dissociation (pupil accommodates but doesn't react to light) are known collectively as Parinaud's syndrome or Dorsal Mid-brain syndrome, are the only physical symptoms seen. This is caused by the compression of the vertical gaze center in the midbrain tectum at the level of the superior colliculus and cranial nerve III. Work-up usually includes Neuro-imaging as seen on the right. A pinealoma may cause interruption of hypo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Walter Dandy
Walter Edward Dandy (April 6, 1886 – April 19, 1946) was an American neurosurgeon and scientist. He is considered one of the founding fathers of neurosurgery, along with Victor Horsley and Harvey Cushing. Dandy is credited with numerous neurosurgical discoveries and innovations, including the description of the circulation of cerebrospinal fluid in the brain, surgical treatment of hydrocephalus, the invention of air ventriculography and pneumoencephalography, the description of brain endoscopy, the establishment of the first intensive care unit, and the first clipping of an intracranial aneurysm, which marked the birth of cerebrovascular neurosurgery. During his 40-year medical career, Dandy published five books and more than 160 peer-reviewed articles while conducting a full-time, ground-breaking neurosurgical practice in which he performed during his peak years about 1000 operations per year. He was recognized at the time as a remarkably fast and particularly dexterous surgeo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |