Shruti Naik (actor)
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Shruti Naik (actor)
Shruti Naik is an Indian American scientist who is known for her interdisciplinary research in immunology and adult stem cell biology. She is an Associate Professor of Immunology and Immunotherapy, Dermatology, and Institute of Regenerative Medicine and Director of the Tissue Repair Program at Icahn School of Medicine at Mount Sinai. Her lab combines approaches from the fields of immunology, microbiology, stem cell biology, and cancer biology with cutting-edge imaging and sequencing technologies to discover new ways of treating inflammatory diseases. Naik’s discoveries have received international acclaim. Her accolades include the Regeneron Prize for Creative Innovation, L'Oréal-UNESCO For Women in Science Award, the 2018 regional Blavatnik Awards for Young Scientists, and the International Takeda Innovator in Regeneration Award. Naik was named a Packard Fellow for her research into the molecular mechanisms that underpin the function of tissue stem cells. She has also rec ...
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University Of Pennsylvania
The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of founder and first president Benjamin Franklin, who had advocated for an educational institution that trained leaders in academia, commerce, and public service. The university has four undergraduate schools and 12 graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the University of Pennsylvania School of Engineering and Applied Science, School of Engineering and Applied Science, the Wharton School, and the University of Pennsylvania School of Nursing, School of Nursing. Among its graduate schools are its University of Pennsylvania Law School, law school, whose first professor, James Wilson (Founding Father), James Wilson, helped write the Constitution of the United States, U.S. Cons ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ...
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David And Lucile Packard Foundation
The David and Lucile Packard Foundation is a private foundation that provides grants to not-for-profit organizations. It was created in 1964 by David Packard (co-founder of HP) and his wife Lucile Salter Packard. Following David Packard's death in 1996, the Foundation became the beneficiary of part of his estate. The foundation's goals, through the use of grants, are to "improve the lives of children, enable creative pursuit of science, advance reproductive health, and conserve and restore earth's natural systems." As of 2016, The David and Lucile Packard Foundation was the 20th wealthiest foundation in the United States. Financials As of December 2015, the Foundation's investment portfolio totaled $6.7 billion. General program grant awards for 2015 totaled $307 million. According to the OECD, the David and Lucile Packard Foundation provided US$122.9 million for development in 2018, all of which was related to its grant-making activities. Areas of funding The majority of ...
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The Pew Charitable Trusts
The Pew Charitable Trusts is an independent non-profit, non-governmental organization (NGO), founded in 1948. Pew's stated mission is to serve the public interest by "improving public policy, informing the public, and invigorating civic life". Pew operates projects and conducts research across five main areas: communities, conservation, finance and economy, governing, and health. In addition, the Pew Research Center is a nonpartisan public polling and think tank that operates as a subsidiary of The Pew Charitable Trusts. History 20th century Pew was established by the merging of several charitable trusts that had been established between 1948 and 1979. The original trusts were created by J. Howard Pew, Mary Ethel Pew, Joseph N. Pew Jr., and Mabel Pew Myrin, the adult sons and daughters of Sun Oil Company founder Joseph N. Pew and his wife, Mary Anderson Pew. Honoring their parents' religious conviction that good works should be done quietly, the original Pew Memorial Foundat ...
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National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ...
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Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon and the rectum. Signs and symptoms In spite of Crohn's and UC being very different diseases, both may present with any of the following symptoms: abdominal pain, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss. Anemia is the most prevalent extraintestinal complication of inflammatory bowel disease (IBD). Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS). Associations with deep vein thrombosis (DVT) and bronchiolitis obliterans organizing pneumonia (BOOP) have also been reported. ...
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Psoriasis
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small localized patches to complete body coverage. Injury to the skin can trigger psoriatic skin changes at that spot, which is known as the Koebner phenomenon. The five main types of psoriasis are plaque, guttate, inverse, pustular, and erythrodermic. Plaque psoriasis, also known as psoriasis vulgaris, makes up about 90% of cases. It typically presents as red patches with white scales on top. Areas of the body most commonly affected are the back of the forearms, shins, navel area, and scalp. Guttate psoriasis has drop-shaped lesions. Pustular psoriasis presents as small, noninfectious, pus-filled blisters. Inverse psoriasis forms red patches in skin folds. Erythrodermic psoriasis occurs when the rash becomes very widespread and can develop from any of the other types. ...
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Hypoxia (medicine)
Hypoxia is a condition in which the body or a region of the body is deprived of an adequate oxygen supply at the tissue level. Hypoxia may be classified as either '' generalized'', affecting the whole body, or ''local'', affecting a region of the body. Although hypoxia is often a pathological condition, variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise. Hypoxia differs from hypoxemia and anoxemia, in that hypoxia refers to a state in which oxygen present in a tissue or the whole body is insufficient, whereas hypoxemia and anoxemia refer specifically to states that have low or no oxygen in the blood. Hypoxia in which there is complete absence of oxygen supply is referred to as anoxia. Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised ge ...
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Regeneration (biology)
Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cell (biology), cells, organisms, and ecosystems Resilience (ecology), resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete after which the necrotic tissue becomes Fibrosis, fibrotic. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the Morphogenesis, morphogenic processes that characterize the phenotypic plasticity of Phenotypic trait, traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, rege ...
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Immune System
The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to bacteria, as well as Tumor immunology, cancer cells, Parasitic worm, parasitic worms, and also objects such as wood splinters, distinguishing them from the organism's own healthy biological tissue, tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use humoral immunity, molecules and cell-mediated immunity, cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against bacteriophage, viral infections. Other basic immune mechanisms evolved in ancien ...
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Elaine Fuchs
Elaine V. Fuchs is an American cell biologist known for her work on the biology and molecular mechanisms of mammalian skin and skin diseases, who helped lead the modernization of dermatology. Fuchs pioneered reverse genetics approaches, which assess protein function first and then assess its role in development and disease. In particular, Fuchs researches skin stem cells and their production of hair and skin. She is an investigator at the Howard Hughes Medical Institute and the Rebecca C. Lancefield Professor of Mammalian Cell Biology and Development at The Rockefeller University. Early life and education Fuchs grew up outside Chicago, in a family of scientists—her father, aunt, and sister were also scientists, and her family encouraged her to pursue higher education.Fiona Watt. "Women in Cell Science: Elaine Fuchs", Journal of Cell Science, v. 117, n. 4877-4879 (2004). She said those influences were especially important to her as a child. During an interview with Faiza E ...
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Damon Runyon Cancer Research Foundation
The Damon Runyon Cancer Research Foundation (Damon Runyon) is an American not-for-profit cancer research organization focused on "discovering the talent to discover the cure". The organization states that its goals are to: "identify the best and brightest early career scientists in cancer research, accelerate the translation of scientific discoveries into new diagnostic tools and treatments, and to enable risk-taking on bold new ideas". The organization was founded in 1946 by media personality Walter Winchell in New York City, New York, under the name Damon Runyon Cancer Memorial Fund in memory of his colleague and friend Damon Runyon, a newspaperman and author. History Almost immediately after Runyon's passing on December 10, 1946, Winchell went on the air and asked his audience for contributions to cancer research: Mr. and Mrs. United States! A very dear friend of mine a great newspaperman, a great writer, and a very great guy Damon Runyon, was killed this week by America ...
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