Shakuyaku-kanzo-to
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Shakuyaku-kanzo-to
or ''shao-yao-gan-cao-tang'' () is a traditional herbal medicine used in both Kampo (Japanese) and Chinese medicine. It consists of an equal combination of the roots of Chinese peony root (''Radix Paeoniae'', ''shakuyaku'') and licorice root (''Radix Glycyrrhizae'', ''kanzō''), primarily used for its antispasmodic properties in the treatment of muscle cramps and various other conditions involving smooth and skeletal muscle spasms. The formula was first described in the ''Shanghan Lun'', a classical Chinese medical textbook during the Eastern Han dynasty, and has been standardized in modern Japan for both traditional and clinical use. Its main active compounds, paeoniflorin and glycyrrhizin, are believed to act synergistically at neuromuscular junctions and on prostaglandin synthesis. While generally safe in short-term use, long-term or high-dose intake can cause side effects such as pseudohyperaldosteronism, a hormone-related disorder, due to the effects of glycyrrhizin. Hi ...
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Shakuyakukanzoto
or ''shao-yao-gan-cao-tang'' () is a traditional herbal medicine used in both Kampo (Japanese) and Chinese medicine. It consists of an equal combination of the roots of Chinese peony root (''Radix Paeoniae'', ''shakuyaku'') and licorice root (''Radix Glycyrrhizae'', ''kanzō''), primarily used for its antispasmodic properties in the treatment of muscle cramps and various other conditions involving smooth and skeletal muscle spasms. The formula was first described in the ''Shanghan Lun'', a classical Chinese medical textbook during the Eastern Han dynasty, and has been standardized in modern Japan for both traditional and clinical use. Its main active compounds, paeoniflorin and glycyrrhizin, are believed to act synergistically at neuromuscular junctions and on prostaglandin synthesis. While generally safe in short-term use, long-term or high-dose intake can cause side effects such as pseudohyperaldosteronism, a hormone-related disorder, due to the effects of glycyrrhizin. Hist ...
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Tsumura
Kampō (or Kanpō, 漢方) medicine is the Japanese study and adaptation of Traditional Chinese medicine. Today in Japan, kampo is integrated into the national health care system. In 1967, the Ministry of Health, Labour and Welfare approved 4 kampo medicines for reimbursement under the National Health Insurance (NHI) program. In 1976, 82 kampo medicines were approved by the Ministry of Health, Labour and Welfare. Currently, 148 kampo medicines are approved for reimbursement Rather than modifying formulas as in Traditional Chinese medicine, the Japanese kampo tradition uses fixed combinations of herbs in standardized proportions according to the classical literature of Chinese medicine. kampo medicines are produced by various manufacturers. However, each medicine is composed of exactly the same ingredients under the ministry's standardization methodology. The medicines are therefore prepared under strict manufacturing conditions that rival pharmaceutical companies. Extensive modern ...
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East Asia
East Asia is a geocultural region of Asia. It includes China, Japan, Mongolia, North Korea, South Korea, and Taiwan, plus two special administrative regions of China, Hong Kong and Macau. The economies of Economy of China, China, Economy of Japan, Japan, Economy of South Korea, South Korea, and Economy of Taiwan, Taiwan are among the world's largest and most prosperous. East Asia borders North Asia to the north, Southeast Asia to the south, South Asia to the southwest, and Central Asia to the west. To its east is the Pacific Ocean. East Asia, especially History of China, Chinese civilization, is regarded as one of the earliest Cradle of civilization#China, cradles of civilization. Other ancient civilizations in East Asia that still exist as independent countries in the present day include the History of Japan, Japanese, History of Korea, Korean, and History of Mongolia, Mongolian civilizations. Various other civilizations existed as independent polities in East Asia in the past ...
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Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is a medical condition in which the spinal canal narrows and compresses the nerves and blood vessels at the level of the lumbar vertebrae. Spinal stenosis may also affect the cervical or thoracic region, in which case it is known as cervical spinal stenosis or thoracic spinal stenosis. Lumbar spinal stenosis can cause pain in the low back or buttocks, abnormal sensations, and the absence of sensation (numbness) in the legs, thighs, feet, or buttocks, or loss of bladder and bowel control. The precise cause of LSS is unclear. Narrowing of spinal structures in the spinal cord such as the Spinal canal, central canal, the lateral recesses, or the intervertebral foramen (the opening where a spinal nerve root passes) must be present, but are not sufficient to cause LSS alone. Many people who undergo MRI imaging are found to have such changes but have no symptoms. These changes are commonly seen in people who have spinal degeneration that occurs with aging (e ...
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In Vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, known as clinical trials, and whole plants. Definition ''In vitro'' (Latin language, Latin for "in glass"; often not italicized in English usage) studies are conducted ...
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Cureus
''Cureus:'' ''Journal of Medical Science'' is a web-based open access general medical journal that uses an accelerated pre-publication peer-review and an optional post-publication peer review. It is also the first academic journal which provides authors with step-by-step templates for them to use to write their papers. The journal's founding editors-in-chief are John R. Adler (Stanford University) and Alexander Muacevic (University of Munich). History and publication process The journal was originally started as ''PeerEMed'' in 2009, obtaining its current name in December 2012. Under its system, after an article is published, anyone can review it, but the reviews of experts will be given a higher score. As of December 2022, the journal became part of the Springer Nature group of journals. If certain criteria are met, Cureus does not charge publication fees. Abstracting and indexing The journal has been abstracted and indexed in the Emerging Sources Citation Index. , the journal' ...
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Glycyrrhetinic Acid
Enoxolone (International Nonproprietary Name, INN, British Approved Name, BAN; also known as glycyrrhetinic acid or glycyrrhetic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. The substance has a sweet taste, so it is used in flavoring to mask the bitter taste of drugs like aloe and quinine. It may have some anti-inflammatory activities. One of its metabolites is responsible for the blood pressure-increasing effect of liquorice. Medical uses Oral topical In Turkey, enoxolone is used in a "Anzibel" lozenge in combination with benzocaine (a local anesthetic) and chlorhexidine hydrochloride (an antibacterial). It is found in an over-the-counter "Arthrodont" toothpaste. Evidence for the ingredient's usefulness for plaque and gingivitis is lacking. Skin topical In Japan, enoxolone is an active ingredient in the Salonpas brand of Transdermal analgesic patch, p ...
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Glycyrrhiza Glabra
Liquorice (Commonwealth English) or licorice (American English; see spelling differences; ) is the common name of ''Glycyrrhiza glabra'', a flowering plant of the bean family Fabaceae, from the root of which a sweet, aromatic flavouring is extracted. The liquorice plant is an herbaceous perennial legume native to West Asia, North Africa, and Southern Europe. Liquorice is used as a flavouring in confectionery, tobacco, beverages, and pharmaceuticals, and is marketed as a dietary supplement. Liquorice extracts have been used in herbalism and traditional medicine. Excessive consumption of liquorice (more than per day of pure glycyrrhizinic acid, a key component of liquorice) can lead to undesirable consequences. Clinically, it is suspected that overindulgence in liquorice may manifest as unexplained hypertension, low blood potassium levels (hypokalemia), and muscle weakness in individuals. Consuming liquorice should be avoided during pregnancy. Etymology The word ''liquor ...
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Pharmacopoeia
A pharmacopoeia, pharmacopeia, or pharmacopoea (or the typographically obsolete rendering, ''pharmacopœia''), meaning "drug-making", in its modern technical sense, is a reference work containing directions for the identification of compound medicines. These are published or sanctioned by a government or a medical or pharmaceutical society, giving the work legal authority within a specified jurisdiction. In a broader sense it is a collection of pharmaceutical drug specifications. Descriptions of the individual preparations are called monographs. Etymology The term derives from "making of (healing) medicine, drug-making", a compound of "medicine, drug, poison" (), with the verb "to make" (), and the abstract noun suffix -ία ''-ia''. In early modern editions of Latin texts, the Greek diphthong οι (''oi'') is latinized to its Latin equivalent ''oe'' which is in turn written with the ligature ''œ'', giving the spelling ''pharmacopœia''; in modern UK English, ''œ'' is ...
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European Journal Of Pain
The ''European Journal of Pain'' is the official journal of the European Pain Federation. According to the ''Journal Citation Reports'', the journal has a 2018 impact factor of 3.188.{{cite book , year=2019 , chapter=European Journal of Pain , title=2018 Journal Citation Reports , publisher=Thomson Reuters , edition=Science , series=Web of Science The Web of Science (WoS; previously known as Web of Knowledge) is a paid-access platform that provides (typically via the internet) access to multiple databases that provide reference and citation data from academic journals, conference proceedi ..., title-link=Journal Citation Reports The journal particularly welcomes clinical trials, which are published on an occasional basis. Regular sections in the journal are: * Editorials and Commentaries * Position Papers and Guidelines * Reviews * Original Articles * Letters * Bookshelf Research articles are published under the following subject headings: * Neurobiology * Neurology * Experime ...
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Medicinal Plants
Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including Plant defense against herbivory, defense and protection against insects, fungi, Plant disease resistance, diseases, against parasites and herbivorous mammals. The earliest historical records of herbs are found from the Sumerian civilization, where hundreds of medicinal plants including opium are listed on clay tablets, . The Ebers Papyrus from ancient Egypt, , describes over 850 plant medicines. The Greek physician Pedanius Dioscorides, Dioscorides, who worked in the Roman army, documented over 1000 recipes for medicines using over 600 medicinal plants in , ; this formed the basis of pharmacopoeias for some 1500 years. Drug research sometimes makes use of ethnobotany to search for pharmacologically active substances, and this approach has yielded hundreds of use ...
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Journal Of Ethnopharmacology
The ''Journal of Ethnopharmacology'' is a peer-reviewed medical journal covering the traditional medicinal use of plants and other substances. It is the official journal of the International Society for Ethnopharmacology. The journal is included in the Index Medicus (MEDLINE MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...). References External links * International Society for Ethnopharmacology Pharmacology journals Elsevier academic journals Academic journals established in 1979 English-language journals {{ethno-stub ...
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