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Sense Of Smell
The sense of smell, or olfaction, is the special sense through which smells (or odors) are perceived. The sense of smell has many functions, including detecting desirable foods, hazards, and pheromones, and plays a role in taste. In humans, it occurs when an odor binds to a receptor within the nasal cavity, transmitting a signal through the olfactory system. Glomeruli aggregate signals from these receptors and transmit them to the olfactory bulb, where the sensory input will start to interact with parts of the brain responsible for smell identification, memory, and emotion. There are many different things which can interfere with a normal sense of smell, including damage to the nose or smell receptors, anosmia, upper respiratory infections, traumatic brain injury, and neurodegenerative disease. History of study Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other ...
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Carnation
''Dianthus caryophyllus'' ( ), commonly known as carnation or clove pink, is a species of ''Dianthus'' native to the Mediterranean Basin, Mediterranean region. Its exact natural range is uncertain due to extensive cultivation over the last 2,000 years. Carnations are prized for their vibrant colors, delicate fringed petals, and fragrance. The scent of carnations is often described as spicy, clove-like, or reminiscent of a combination of cinnamon and nutmeg, hence the common name "clove pink". This aroma has made carnations a popular choice for use in perfumes, potpourri, and scented products. They have cultural significance and are associated with love, distinction, and motherly affection. With numerous cultivars and hybrids, carnations offer a wide variety of colors and forms, making them popular for gardens, floral arrangements, and scented products. Overall, carnations are enduring symbols of beauty and grace, treasured by flower enthusiasts and used to convey heartfelt emot ...
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Anosmia
Anosmia, also known as smell blindness, is the lack of ability to detect one or more smells. Anosmia may be temporary or permanent. It differs from hyposmia, which is a decreased sensitivity to some or all smells. Anosmia can be categorized into acquired anosmia and congenital anosmia. Acquired anosmia develops later in life due to various causes, such as upper respiratory infections, head trauma, or neurodegenerative diseases. In contrast, congenital anosmia is present from birth and is typically caused by genetic factors or developmental abnormalities of the olfactory system. While acquired anosmia may have potential treatments depending on the underlying cause, such as medications or surgery, congenital anosmia currently has no known cure, and management focuses on safety precautions and coping strategies. Anosmia can be due to a number of factors, including inflammation of the nasal mucosa, blockage of nasal passages, or destruction of temporal lobular tissue. Anosmia s ...
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Olfactory Receptors
Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible for the detection of odorants (for example, compounds that have an odor) which give rise to the sense of smell. Activated olfactory receptors trigger nerve impulses which transmit information about odor to the brain. In vertebrates, these receptors are members of the class A rhodopsin-like family of G protein-coupled receptors (GPCRs). The olfactory receptors form the largest multigene family in vertebrates consisting of around 400 genes in humans and 1400 genes in mice. In insects, olfactory receptors are members of an unrelated group of ligand-gated ion channels. Expression In vertebrates, the olfactory receptors are located in both the cilia and synapses of the olfactory sensory neurons and in the epithelium of the human airway. Sperm cells also express odorant receptors, which are thought to be involved in ...
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Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ...
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Mammals
A mammal () is a vertebrate animal of the class Mammalia (). Mammals are characterised by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles and birds, from which their ancestors diverged in the Carboniferous Period over 300 million years ago. Around 6,640 extant species of mammals have been described and divided into 27 orders. The study of mammals is called mammalogy. The largest orders of mammals, by number of species, are the rodents, bats, and eulipotyphlans (including hedgehogs, moles and shrews). The next three are the primates (including humans, monkeys and lemurs), the even-toed ungulates (including pigs, camels, and whales), and the Carnivora (including cats, dogs, and seals). Mammals are the only living members of Synapsida; this clade, together with Sauropsida (reptiles and ...
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Nobel Prize
The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred Nobel, Alfred Nobel's death. The original Nobel Prizes covered five fields: Nobel Prize in Physics, physics, Nobel Prize in Chemistry, chemistry, Nobel Prize in Physiology or Medicine, physiology or medicine, Nobel Prize in Literature, literature, and Nobel Peace Prize, peace, specified in Nobel's will. A sixth prize, the Nobel Memorial Prize in Economic Sciences, Prize in Economic Sciences, was established in 1968 by Sveriges Riksbank (Sweden's central bank) in memory of Alfred Nobel. The Nobel Prizes are widely regarded as the most prestigious awards available in their respective fields.Nobel Prize#Shalev69, Shalev, p. 8. Except in extraordinary circumstances, such as war, all six prizes are given annually. Each recipient, known as a laur ...
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Richard Axel
Richard Axel (born July 2, 1946) is an American molecular biologist and university professor in the Department of Neuroscience at Columbia University and investigator at the Howard Hughes Medical Institute. His work on the olfactory system won him and Linda Buck, a former postdoctoral research scientist in his group, the Nobel Prize in Physiology or Medicine in 2004. Education and early life Born in New York City to Polish Jewish immigrants, Axel grew up in Brooklyn. He graduated from Stuyvesant High School in 1963, (along with Bruce Bueno de Mesquita, Allan Lichtman, Ron Silver, and Alexander Rosenberg), received his B.A. in 1967 from Columbia University, and his M.D. in 1971 from Johns Hopkins University. However, he was poorly suited to medicine and graduated on the promise to his department chairman that he would not practice clinically. He found his calling in research and returned to Columbia later that year, eventually becoming a full professor in 1978. Research and ...
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Linda B
Linda is an English feminine given name, derived from the Spanish word , meaning "pretty." Linda may also refer to: Names * Linda (given name), a female given name (including a list of people and fictional characters so named) * Linda (singer) (born 1977), stage name of Svetlana Geiman, a Russian singer * Miss Linda, long-time manager and wife of Welsh wrestler Adrian Street Surname * Anita Linda (born Alice Lake, 1924–2020), Filipino film actress * Bogusław Linda (born 1952), Polish actor * La Prieta Linda (1933–2021), Mexican singer and actress * Sarah Linda (born 1987), British actress and model * Solomon Linda (1909–1962), South African Zulu musician, singer and composer who wrote the song "Mbube" which later became "The Lion Sleeps Tonight" Places * Linda, Tasmania, Australia, a ghost town * Linda Valley, Tasmania * Linda, Georgia, a village in Abkhazia * Linda, Bashkortostan, Russia, a village * Linda, California, United States, a census-designated place ...
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Lucretius
Titus Lucretius Carus ( ; ;  – October 15, 55 BC) was a Roman poet and philosopher. His only known work is the philosophical poem '' De rerum natura'', a didactic work about the tenets and philosophy of Epicureanism, which usually is translated into English as ''On the Nature of Things''—and somewhat less often as ''On the Nature of the Universe''. Very little is known about Lucretius's life; the only certainty is that he was either a friend or client of Gaius Memmius, to whom the poem was addressed and dedicated. ''De rerum natura'' was a considerable influence on the Augustan poets, particularly Virgil (in his ''Aeneid'' and ''Georgics'', and to a lesser extent on the '' Eclogues'') and Horace. The work was almost lost during the Middle Ages, but was rediscovered in 1417 in a monastery in Germany by Poggio Bracciolini and it played an important role both in the development of atomism (Lucretius was an important influence on Pierre Gassendi) and the efforts of ...
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Stimulus Modality
Stimulus modality, also called sensory modality, is one aspect of a stimulus or what is perceived after a stimulus. For example, the temperature modality is registered after heat or cold stimulate a receptor. Some sensory modalities include: light, sound, temperature, taste, pressure, and smell. The type and location of the sensory receptor activated by the stimulus plays the primary role in coding the sensation. All sensory modalities work together to heighten stimuli sensation when necessary. Multimodal perception Multimodal perception is the ability of the mammalian nervous system to combine all of the different inputs of the sensory nervous system to result in an enhanced detection or identification of a particular stimulus. Combinations of all sensory modalities are done in cases where a single sensory modality results in an ambiguous and incomplete result. Integration of all sensory modalities occurs when multimodal neurons receive sensory information which overlap ...
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Eleanor Gamble
Eleanor Acheson McCulloch Gamble (March 2, 1868 – August 30, 1933) was an influential American psychologist from the late 19th century through the early 20th century. Gamble published most of her work on audition and memory influenced by Georg Elias Müller, Edward B. Titchener, Mary Whiton Calkins, and Ernst Heinrich Weber. Despite her chronic eye conditions she was successful in editing volumes of textbooks, her own papers, and directing many master's degree students. She earned her undergraduate degree from Wellesley College in 1889. She went on to obtain her doctorate from Cornell University in 1898. She held several teaching positions over the course of her career and was a member of several influential organizations including the American Psychological Association (APA). Gamble was a distinguished and well-liked professor at Wellesley College for more than two decades, and by 1930 she was the head of the Department of Philosophy and Psychology following the death of Mar ...
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