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Sarracenin
Sarracenin is an iridoid found in several plant species in the carnivorous family Sarraceniaceae. It also occurs in other non-carnivorous plants such as ''Strychnos spinosa'' (Loganiaceae) and ''Patrinia heterophylla'' (Caprifoliaceae). History Sarracenin was first isolated from the roots of '' Sarracenia flava'' in 1976. Analysis of ''S. flava'' extracts was prompted by their use as a folk remedy by people of the Okefenokee swamp region Biosynthesis Sarracenin is believed to be derived from loganin, with either morronoside or secologanin serving as intermediates in the biosynthetic process. Uses Sarracenin displays antimicrobial activity against several pathogens including ''Staphylococcus aureus'', ''Streptococcus pyogenes'', ''Shigella dysenteriae'', '' Klebsiella pneumonia'', ''Candida albicans,'' ''Candida tropicalis'', ''Candida thrusei'', and ''Candida stellatoidea''. It has also demonstrated cytotoxicity against three tumor cell lines: A375 (human melanoma cell), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iridoid
Iridoids are a type of monoterpenoids in the general form of cyclopentanopyran, found in a wide variety of plants and some animals. They are biosynthetically derived from 8-oxogeranial. Iridoids are typically found in plants as glycosides, most often bound to glucose. The chemical structure is exemplified by iridomyrmecin, a defensive chemical produced by the ant genus '' Iridomyrmex'', for which iridoids are named. Structurally, they are bicyclic ''cis''-fused cyclopentane-pyrans. Cleavage of a bond in the cyclopentane ring gives rise to a subclass known as ''secoiridoids'', such as oleuropein and amarogentin. Occurrence The iridoids produced by plants act primarily as a defense against herbivores or against infection by microorganisms. The variable checkerspot butterfly also contains iridoids obtained through its diet which act as a defense against avian predators. To humans and other mammals, iridoids are often characterized by a deterrent bitter taste. Aucubin a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candida Tropicalis
''Candida tropicalis'' is a species of yeast in the genus ''Candida (fungus), Candida''. It is a common pathogen in neutropenic hosts, in whom it may spread through the bloodstream to peripheral organs. For invasive disease, treatments include amphotericin B, echinocandins, or extended-spectrum triazole antifungals. History and taxonomy In the history of fungi, the name of genus ''Candida'', derived from the family Debaryomycetaceae, comes from the Latin term "" which has the meaning of “glowing white” and also refers to as smooth and glistering. Genus ''Candida'' referred to any asexual yeast without any of the following characteristics: production of acetic acid, pigments of colours red, pink or orange, arthroconidia, unipolar or bipolar budding, enteroblastic-basipetal budding, blastoconidia formation on sympodulae, buds formation on stalks, triangular cells, needle-shaped terminal conidia, and having the ability to grow on inositol as a sole carbon source. Although there a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterocyclic Compounds With 3 Rings
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of heterocyclic chemistry focuses especially on unsaturated derivatives, and the preponderance of work and applications involves unstrained 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of pyridine, thiophene, pyrrole, and furan are quin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iridoid Glycosides
Iridoids are a type of monoterpenoids in the general form of cyclopentanopyran, found in a wide variety of plants and some animals. They are biosynthetically derived from 8-oxogeranial. Iridoids are typically found in plants as glycosides, most often bound to glucose. The chemical structure is exemplified by iridomyrmecin, a defensive chemical produced by the ant genus ''Iridomyrmex'', for which iridoids are named. Structurally, they are bicyclic ''cis''-fused cyclopentane-pyrans. Cleavage of a bond in the cyclopentane ring gives rise to a subclass known as ''secoiridoids'', such as oleuropein and amarogentin. Occurrence The iridoids produced by plants act primarily as a defense against herbivores or against infection by microorganisms. The variable checkerspot butterfly also contains iridoids obtained through its diet which act as a defense against avian predators. To humans and other mammals, iridoids are often characterized by a deterrent bitter taste. Aucubin and cata ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarracenia
''Sarracenia'' ( or ) is a genus comprising 8 to 11 species of North American pitcher plants, commonly called trumpet pitchers. The genus belongs to the family Sarraceniaceae, which also contain the closely allied genera '' Darlingtonia'' and ''Heliamphora''. ''Sarracenia'' is a genus of carnivorous plants indigenous to the eastern seaboard of the United States, Texas, the Great Lakes area and southeastern Canada, with most species occurring only in the south-east United States (only '' S. purpurea'' occurs in cold-temperate regions). The plant's leaves have evolved into a funnel or pitcher shape in order to trap insects. The plant attracts its insect prey with secretions from extrafloral nectaries on the lip of the pitcher leaves, as well as a combination of the leaves' color and scent. Slippery footing at the pitcher's rim, causes insects to fall inside, where they die and are digested by the plant with proteases and other enzymes. Description ''Sarracenia'' are herb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Darlingtonia Californica
''Darlingtonia californica'' , also called the California pitcher plant, cobra lily, or cobra plant, is a species of carnivorous plant. It is the sole member of the genus ''Darlingtonia'' in the family Sarraceniaceae. This pitcher plant is native to Northern California and Oregon, US, growing in bogs and seeps with cold running water usually on serpentine soils. This plant is designated as uncommon due to its rarity in the field. The name "cobra lily" stems from the resemblance of its tubular leaves to a rearing cobra, complete with a forked leaf – ranging from yellow to purplish-green – that resemble fangs or a serpent's tongue. The plant was discovered in 1841 by the botanist William D. Brackenridge at Mount Shasta. In 1853 it was described by John Torrey, who named the genus ''Darlingtonia'' after the Philadelphian botanist William Darlington (1782–1863). In cultivation in the UK this plant has gained the Royal Horticultural Society's Award of Garden Merit. Bio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heliamphora
The genus ''Heliamphora'' ( or ; Greek: ''helos'' " marsh" and ''amphoreus'' "amphora") contains 23 species of pitcher plants endemic to South America.McPherson, S., A. Wistuba, A. Fleischmann & J. Nerz 2011. '' Sarraceniaceae of South America''. Redfern Natural History Productions, Poole. The species are collectively known as sun pitchers, based on the mistaken notion that the ''heli'' of ''Heliamphora'' is from the Greek ''helios'', meaning "sun". In fact, the name derives from ''helos'', meaning marsh, so a more accurate translation of their scientific name would be marsh pitcher plants. Species in the genus ''Heliamphora'' are carnivorous plants that consist of a modified leaf form that is fused into a tubular shape. They have evolved mechanisms to attract, trap, and kill insects; and control the amount of water in the pitcher. At least one species ('' H. tatei'') produces its own proteolytic enzymes that allows it to digest its prey without the help of symbiotic bacte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HeLa
HeLa (; also Hela or hela) is an immortalized cell line used in scientific research. It is the oldest and most commonly used human cell line. The line is derived from cervical cancer cells taken on February 8, 1951, named after Henrietta Lacks, a 31-year-old African-American mother of five, who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which allows it to be used extensively in scientific study. The cells from Lacks's cancerous cervical tumor were taken without her knowledge or consent, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would only survive for a few days. Cells from Lacks's tumor behaved differently. History Origin In 1951, a patient named Henrietta Lacks was admitted to the Johns Hopkins Hospital with symptoms of irregular vaginal bleeding, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candida Stellatoidea
''Candida albicans'' is an opportunistic pathogenic yeast that is a common member of the human gut flora. It can also survive outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism, but it can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the genus '' Candida'' that causes the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is, for example, often observed in HIV-infected patients. ''C. albicans'' is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. ''C. albicans'', ''C. tropicalis'', ''C. parapsilosis'', and ''C. glabrata'' are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to ''C. albicans' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candida Thrusei
Candida, or Cándida (Spanish), may refer to: Biology and medicine * ''Candida'' (fungus), a genus of yeasts ** Candidiasis, an infection by ''Candida'' organisms * Malvasia Candida, a variety of grape Places * Candida, Campania, a ''comune'' in Avellino, Italy * Candida Casa, a church in Whithorn, Dumfries and Galloway, Scotland * Aguas Cándidas, a municipality in Burgos, Castile and León, Spain People * Candida (given name) * Aldoino Filangieri di Candida (died 1283), nobleman in the Kingdom of Naples * Candida Maria de Jesus (1845–1912), Spanish nun and saint * Candida, pen name of Eibhlín Ní Bhriain (1925–1986) Theatre, film and performing arts * ''Candida'' (play), by George Bernard Shaw ** ''Candida'' (1962 film), an Australian television adaptation * ''Cándida'' (1939 film), a 1939 Argentine musical film drama directed by Luis Bayon Herrera **This film was followed by several others featuring the same character played by Nini Marshall including: ** '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candida Albicans
''Candida albicans'' is an opportunistic pathogenic yeast that is a common member of the human gut flora. It can also survive outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism, but it can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the genus '' Candida'' that causes the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is, for example, often observed in HIV-infected patients. ''C. albicans'' is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. ''C. albicans'', ''C. tropicalis'', ''C. parapsilosis'', and ''C. glabrata'' are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to ''C. albicans''. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarraceniaceae
Sarraceniaceae are a family of pitcher plants, belonging to order Ericales (previously Nepenthales). The family comprises three extant genera: '' Sarracenia'' (North American pitcher plants), '' Darlingtonia'' (the cobra lily or California pitcher plant), and ''Heliamphora'' (sun pitchers). The extinct '' Archaeamphora longicervia'' may also belong to this family, although later studies question that interpretation. All three are carnivorous plants that lure insects with nectar and use their elongated, tube-shaped leaves filled with water and digestive enzymes to catch and consume them. Digestive enzymes are not always produced by the plants themselves. Digestive mutualisms are common in Sarraceniaceae: both ''Sarracenia'' and ''Darlingtonia'' rely on commensal bacteria to supplement or produce all of their enzymes. Many species also use downward-pointing hairs and waxy secretions to make it difficult for insects to escape. ''Sarracenia'' and ''Darlingtonia'' are native to No ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
