Sarolaner
Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. It is also used off-label to control sarcoptic mange and demodectic mange. Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. It is used for prevention of heartworm disease caused by ''Dirofilaria immitis''; treat and prevent flea infestations; treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick; and treat and control roundworm and adult hookworm infections. Sarolaner is also an ingredient in feline Combination drug, combination antiparasitic Revolution Plus (or Stronghold Plus), which contains sarolaner and selamectin and is used for prevention of sarcoptic mange, feline Hookworm, hookworms, feline roundworms, Ear mite, ear mites, and Dirofilaria immitis, heartworms, as well as ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not directly related to food or drugs, but involves such things as regulating lasers, cellular phones, and condoms, as well as control of disease in contexts v ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Roundworm
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega jo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Acaricides
Acaricides are pesticides that kill members of the arachnid subclass ''Acari'', which includes ticks and mites. Acaricides are used both in medicine and agriculture, although the desired selective toxicity differs between the two fields. Terminology More specific words are sometimes used, depending upon the targeted group: * "Ixodicides" are substances that kill ticks. * "Miticides" are substances that kill mites. *The term scabicide is more narrow, and refers to agents specifically targeting '' Sarcoptes''. *The term "arachnicide" is more general, and refers to agents that target arachnids. This term is used much more rarely, but occasionally appears in informal writing. As a practical matter, mites are a paraphyletic grouping, and mites and ticks are usually treated as a single group. Examples Examples include: * Permethrin can be applied as a spray. The effects are not limited to mites: lice, cockroaches, fleas, mosquitos, and other insects will be affected. * Ivermectin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Insecticides
Insecticides are substances used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. Insecticides are used in agriculture, medicine, industry and by consumers. Insecticides are claimed to be a major factor behind the increase in the 20th-century's agricultural productivity. Nearly all insecticides have the potential to significantly alter ecosystems; many are toxic to humans and/or animals; some become concentrated as they spread along the food chain. Insecticides can be classified into two major groups: systemic insecticides, which have residual or long term activity; and contact insecticides, which have no residual activity. The mode of action describes how the pesticide kills or inactivates a pest. It provides another way of classifying insecticides. Mode of action can be important in understanding whether an insecticide will be toxic to unrelated species, such as fish, birds and mammals. Insecticides may be repelle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dog Medications
The dog (''Canis familiaris'' or ''Canis lupus familiaris'') is a domesticated descendant of the wolf. Also called the domestic dog, it is derived from the extinct Pleistocene wolf, and the modern wolf is the dog's nearest living relative. Dogs were the first species to be domesticated by hunter-gatherers over 15,000 years ago before the development of agriculture. Due to their long association with humans, dogs have expanded to a large number of domestic individuals and gained the ability to thrive on a starch-rich diet that would be inadequate for other canids. The dog has been selectively bred over millennia for various behaviors, sensory capabilities, and physical attributes. Dog breeds vary widely in shape, size, and color. They perform many roles for humans, such as hunting, herding, pulling loads, protection, assisting police and the military, companionship, therapy, and aiding disabled people. Over the millennia, dogs became uniquely adapted to human behavior, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cat Medications
The cat (''Felis catus'') is a Domestication of the cat, domestic species of small carnivorous mammal. It is the only domesticated species in the family Felidae and is commonly referred to as the domestic cat or house cat to distinguish it from the wild members of the family. Cats are commonly kept as house pets but can also be farm cats or feral cats; the feral cat ranges freely and avoids human contact. Domestic cats are valued by humans for companionship and their ability to kill rodents. About 60 cat breeds are recognized by various cat registries. The cat is similar in Cat anatomy, anatomy to the other felid species: they have a strong flexible body, quick reflexes, sharp teeth, and retractable claws adapted to killing small prey. Their night vision and sense of smell are well developed. Cat communication includes Animal communication, vocalizations like meowing, purring, trilling, hissing, growling, and grunting as well as Cat body language, cat-specific body language. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tick
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are from the Cretaceous period, around 100 million years old. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families, the Ixodidae or hard ticks, and the Argasidae, or soft ticks. '' Nuttalliella,'' a genus of tick from southern Africa is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalothorax and abdomen are completely fused. In ad ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Flea
Flea, the common name for the order Siphonaptera, includes 2,500 species of small flightless insects that live as external parasites of mammals and birds. Fleas live by ingesting the blood of their hosts. Adult fleas grow to about long, are usually brown, and have bodies that are "flattened" sideways or narrow, enabling them to move through their hosts' fur or feathers. They lack wings; their hind legs are extremely well adapted for jumping. Their claws keep them from being dislodged, and their mouthparts are adapted for piercing skin and sucking blood. They can leap 50 times their body length, a feat second only to jumps made by another group of insects, the superfamily of froghoppers. Flea larvae are worm-like, with no limbs; they have chewing mouthparts and feed on organic debris left on their hosts' skin. Genetic evidence indicates that fleas are a specialised lineage of parasitic scorpionflies (Mecoptera) ''sensu lato'', most closely related to the family Nannochor ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ear Mite
Ear mites are mites that live in the ears of animals and humans. The most commonly seen species in veterinary medicine is '' Otodectes cynotis'' (Gk. ''oto''=ear, ''dectes''=biter, ''cynotis''=of the dog). This species, despite its name, is also responsible for 90% of ear mite infections in felines. In veterinary practice, ear mite infections in dogs and cats may present as a disease that causes intense itching in one or both ears, which in turn triggers scratching at the affected ear. An unusually dark colored ear wax (cerumen) may also be produced. Cats, as well as dogs with erect ears that have control over ear direction, may be seen with one or both ear pinnas held at an odd or flattened angle. The most common lesion associated with ear mites is an open or crusted ("scabbed") skin wound at the back or base of the ear, caused by abrasion of the skin by hind limb claws, as the ear has been scratched in an attempt to relieve the itching. This lesion often becomes secondarily in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Roundworms
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega journ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hookworm
Hookworms are intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases. Hookworm infection is found in many parts of the world, and is common in areas with poor access to adequate water, sanitation, and hygiene. In humans, infections are caused by two main species of roundworm, belonging to the genera ''Ancylostoma'' and '' Necator''. In other animals the main parasites are species of ''Ancylostoma''. Species The two most common types of hookworm that infect humans are ''Ancylostoma duodenale'' and '' Necator americanus''. Hookworm species that are known to infect domestic cats are '' Ancylostoma braziliense'' and '' Ancylostoma tubaeforme''. Wild cats are infected by '' Ancylostoma pluridentatum''. Dogs are commonly infected by '' Ancylostoma caninum'', but may also be infected by '' Uncinaria stenocephala'' and ''Ancylostoma braziliense''. In Asia, '' Ancylostoma ceylanicum'' is endemic among dogs and cats and infects humans. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Selamectin
Selamectin (trade names Revolution and Stronghold manufactured by Zoetis, and Revolt manufactured by Aurora Pharmaceuticals, among others) is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. It is structurally related to ivermectin and milbemycin. Selamectin is not approved for human use. Usage The drug is applied topically. It is isopropyl alcohol based, packaged according to its varying dosage sizes and applied once monthly. It is not miscible in water. Mode of action Selamectin disables parasites by activating glutamate-gated chloride channels at muscle synapses. Selamectin activates the chloride channel without desensitization, allowing chloride ions to enter the nerve cells and causing neuromuscular paralysis, impaired muscular contraction, and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |