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Samandarin
Samandarin or Samandarine is the main steroidal alkaloid secreted by the fire salamander (''Salamandra salamandra''). The compound is extremely toxic ( LD50 = 70 μg/kg in mice). Poisoning can cause convulsions, respiratory paralysis, and eventual death. Samandarin is also believed to be the active ingredient in Salamander brandy, a Slovenian traditional medicinal alcoholic drink with purported hallucinogenic and aphrodisiac effects. Samandarine family Samandarin belongs to a family of toxic compounds called samandarines. Samandarines are biologically active, lipid-soluble steroidal alkaloids. They all contain a similar 7-6-6-5 fused ring system. Nine structures in this family have been characterized. Samandarines are exclusively produced and secreted by the fire salamander through their parotoid glands (20 mg/gland). Samandarin is the main component of these glandular secretions, although the precise ratio of the alkaloids can vary from species to species and ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Samandarine Family
Samandarin or Samandarine is the main steroidal alkaloid secreted by the fire salamander (''Salamandra salamandra''). The compound is extremely toxic (LD50, LD50 = 70 μg/kg in mice). Poisoning can cause convulsions, respiratory paralysis, and eventual death. Samandarin is also believed to be the active ingredient in Salamander brandy, a Slovenian traditional medicine, traditional medicinal Alcoholic beverage, alcoholic drink with purported hallucinogenic and aphrodisiac effects. Samandarine family Samandarin belongs to a family of toxic compounds called samandarines. Samandarines are biologically active, lipid-soluble steroidal alkaloids. They all contain a similar 7-6-6-5 fused ring system. Nine structures in this family have been characterized. Samandarines are exclusively produced and secreted by the fire salamander through their parotoid glands (20 mg/gland). Samandarin is the main component of these glandular secretions, although the precise ratio of the alkalo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
